Full Text Journal Articles by
Author Peter V S Lee

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Measurement of normal and pathological mandibular and temporomandibular joint kinematics: A systematic review.

Sarah C Woodford, Dale L Robinson, Albert Mehl, Peter V S Lee, David C Ackland,

Motion of the mandible and temporomandibular joint (TMJ) plays a pivotal role in the function of the dentition and associated hard and soft tissue structures, and facilitates mastication, oral communication and access to respiratory and digestive systems. Quantification of TMJ kinematics is clinically relevant in cases of prosthetic rehabilitations, TMJ ... Read more >>

J Biomech (Journal of biomechanics)
[2020, 111:109994]

Cited: 1 time

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Surface area-to-volume ratio, not cellular viscoelasticity, is the major determinant of red blood cell traversal through small channels.

Arman Namvar, Adam J Blanch, Matthew W Dixon, Olivia M S Carmo, Boyin Liu, Snigdha Tiash, Oliver Looker, Dean Andrew, Li-Jin Chan, Wai-Hong Tham, Peter V S Lee, Vijay Rajagopal, Leann Tilley,

The remarkable deformability of red blood cells (RBCs) depends on the viscoelasticity of the plasma membrane and cell contents and the surface area to volume (SA:V) ratio; however, it remains unclear which of these factors is the key determinant for passage through small capillaries. We used a microfluidic device to ... Read more >>

Cell Microbiol (Cellular microbiology)
[2021, 23(1):e13270]

Cited: 2 times

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Bone Measures by Dual-Energy X-Ray Absorptiometry and Peripheral Quantitative Computed Tomography in Young Women With Type 1 Diabetes Mellitus.

Hongyuan Jiang, Dale L Robinson, Alison Nankervis, Suzanne M Garland, Emma T Callegari, Sarah Price, Peter V S Lee, John D Wark,

Understanding bone fragility in young adult females with type 1 diabetes mellitus (T1DM) is of great clinical importance since the high fracture risk in this population remains unexplained. This study aimed to investigate bone health in young adult T1DM females by comparing relevant variables determined by dual-energy X-ray absorptiometry (DXA), ... Read more >>

J Clin Densitom (Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry)
[2021, 24(2):259-267]

Cited: 0 times

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A novel rat model of heterotopic ossification after polytrauma with traumatic brain injury.

Rhys D Brady, Michael Z Zhao, Ker R Wong, Pablo M Casilla-Espinosa, Glenn R Yamakawa, Ryan C Wortman, Mujun Sun, Brian L Grills, Richelle Mychasiuk, Terence J O'Brien, Denes V Agoston, Peter V S Lee, Stuart J McDonald, Dale L Robinson, Sandy R Shultz,

Neurological heterotopic ossification (NHO) is characterized by abnormal bone growth in soft tissue and joints in response to injury to the central nervous system. The ectopic bone frequently causes pain, restricts mobility, and decreases the quality of life for those affected. NHO commonly develops in severe traumatic brain injury (TBI) ... Read more >>

Bone (Bone)
[2020, 133:115263]

Cited: 2 times

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Predicting experimentally-derived failure load at the distal radius using finite element modelling based on peripheral quantitative computed tomography cross-sections (pQCT-FE): A validation study.

Hongyuan Jiang, Dale L Robinson, Matthew McDonald, Peter V S Lee, Saija A Kontulainen, James D Johnston, Christopher J Yates, John D Wark,

Dual energy X-ray absorptiometry, the current clinical criterion method for osteoporosis diagnosis, has limitations in identifying individuals with increased fracture risk, especially at the distal radius. Peripheral quantitative computed tomography (pQCT) can provide volumetric bone density data, as well as information on bone geometry, which makes it possible to establish ... Read more >>

Bone (Bone)
[2019, 129:115051]

Cited: 1 time

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The relationship between microstructure, stiffness and compressive fatigue life of equine subchondral bone.

Sandra Martig, Peta L Hitchens, Peter V S Lee, R Chris Whitton,

Subchondral bone injuries often precede articular cartilage damage in osteoarthritis and are common in thoroughbred racehorses due to the accumulation of fatigue damage from high speed racing and training. Thus, racehorses provide a model to investigate the role of subchondral bone in joint disease. We assessed the association of horse ... Read more >>

J Mech Behav Biomed Mater (Journal of the mechanical behavior of biomedical materials)
[2020, 101:103439]

Cited: 2 times

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Shock absorbing ability in healthy and damaged cartilage-bone under high-rate compression.

Shaktivesh, Fatemeh Malekipour, Peter V S Lee,

Articular cartilage is a soft tissue that distributes the loads in joints and transfers the compressive load to the underlying bone. At high rate and magnitudes of mechanical loading, cartilage and subchondral bone together are susceptible to damage. In addition, any disruption to the cartilage's structure, caused by injury, trauma ... Read more >>

J Mech Behav Biomed Mater (Journal of the mechanical behavior of biomedical materials)
[2019, 90:388-394]

Cited: 2 times

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The functional, spatio-temporal and satisfaction outcomes of transtibial amputees with a hydrocast socket following an extended usage period in an under-resourced environment.

Sheridan Laing, Peter V S Lee, Jim Lavranos, Noel Lythgo,

<h4>Background</h4>Transtibial hydrocast sockets have been shown to be a potential alternative to hand-cast patella-tendon bearing sockets, the use of which would have particular benefits in under-resourced environments. However, data concerning wearer outcomes of hard hydrocast sockets (i.e. those without silicone liners), especially over long-term usage periods, is scarce in the ... Read more >>

Gait Posture (Gait & posture)
[2018, 66:88-93]

Cited: 2 times

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Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis.

Christine R Keenan, Shenna Y Langenbach, Fernando Jativa, Trudi Harris, Meina Li, Qianyu Chen, Yuxiu Xia, Bryan Gao, Michael J Schuliga, Jade Jaffar, Danica Prodanovic, Yan Tu, Asres Berhan, Peter V S Lee, Glen P Westall, Alastair G Stewart,

Transforming growth factor-beta (TGF-β) is a major mediator of fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). However, therapeutic global inhibition of TGF-β is limited by unwanted immunosuppression and mitral valve defects. We performed an extensive literature search to uncover a little-known connection between TGF-β signaling and casein kinase (CK) activity. ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2018, 9:738]

Cited: 9 times

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A novel computational method to determine subject-specific bite force and occlusal loading during mastication.

Oliver Röhrle, Harnoor Saini, Peter V S Lee, David C Ackland,

The evaluation of three-dimensional occlusal loading during biting and chewing may assist in development of new dental materials, in designing effective and long-lasting restorations such as crowns and bridges, and for evaluating functional performance of prosthodontic components such as dental and/or maxillofacial implants. At present, little is known about the ... Read more >>

Comput Methods Biomech Biomed Engin (Computer methods in biomechanics and biomedical engineering)
[2018, 21(6):453-460]

Cited: 3 times

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Modulation of shoulder muscle and joint function using a powered upper-limb exoskeleton.

Wen Wu, Justin Fong, Vincent Crocher, Peter V S Lee, Denny Oetomo, Ying Tan, David C Ackland,

Robotic-assistive exoskeletons can enable frequent repetitive movements without the presence of a full-time therapist; however, human-machine interaction and the capacity of powered exoskeletons to attenuate shoulder muscle and joint loading is poorly understood. This study aimed to quantify shoulder muscle and joint force during assisted activities of daily living using ... Read more >>

J Biomech (Journal of biomechanics)
[2018, 72:7-16]

Cited: 1 time

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Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.

Michael Schuliga, Jade Jaffar, Asres Berhan, Shenna Langenbach, Trudi Harris, David Waters, Peter V S Lee, Christopher Grainge, Glen Westall, Darryl Knight, Alastair G Stewart,

In lung injury and disease, including idiopathic pulmonary fibrosis (IPF), extravascular factor X is converted into factor Xa (FXa), a coagulant protease with fibrogenic actions. Extracellular annexin A2 binds to FXa, augmenting activation of the protease-activated receptor-1 (PAR-1). In this study, the contribution of annexin A2 in lung injury and ... Read more >>

Am J Physiol Lung Cell Mol Physiol (American journal of physiology. Lung cellular and molecular physiology)
[2017, 312(5):L772-L782]

Cited: 6 times

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Microstructure Variations in the Soft-Hard Tissue Junction of the Human Anterior Cruciate Ligament.

Lei Zhao, Peter V S Lee, David C Ackland, Neil D Broom, Ashvin Thambyah,

The role of the sub-bundles in the anterior cruciate ligament (ACL) has been defined, such that the anterior-medial bundle directly resists anterior tibial translation while the posterior lateral bundle is involved in rotational stability. With regards to this biomechanical function, much of the previous work on bundle-specific morphology has been ... Read more >>

Anat Rec (Hoboken) (Anatomical record (Hoboken, N.J. : 2007))
[2017, 300(9):1547-1559]

Cited: 0 times

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Subject-specific musculoskeletal modeling in the evaluation of shoulder muscle and joint function.

Wen Wu, Peter V S Lee, Adam L Bryant, Mary Galea, David C Ackland,

Upper limb muscle force estimation using Hill-type muscle models depends on musculotendon parameter values, which cannot be readily measured non-invasively. Generic and scaled-generic parameters may be quickly and easily employed, but these approaches do not account for an individual subject's joint torque capacity. The objective of the present study was ... Read more >>

J Biomech (Journal of biomechanics)
[2016, 49(15):3626-3634]

Cited: 7 times

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Prophylactic knee bracing alters lower-limb muscle forces during a double-leg drop landing.

Katie A Ewing, Justin W Fernandez, Rezaul K Begg, Mary P Galea, Peter V S Lee,

Anterior cruciate ligament (ACL) injury can be a painful, debilitating and costly consequence of participating in sporting activities. Prophylactic knee bracing aims to reduce the number and severity of ACL injury, which commonly occurs during landing maneuvers and is more prevalent in female athletes, but a consensus on the effectiveness ... Read more >>

J Biomech (Journal of biomechanics)
[2016, 49(14):3347-3354]

Cited: 5 times

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Effects of Prophylactic Knee Bracing on Lower Limb Kinematics, Kinetics, and Energetics During Double-Leg Drop Landing at 2 Heights.

Katie A Ewing, Rezaul K Begg, Mary P Galea, Peter V S Lee,

<h4>Background</h4>Anterior cruciate ligament (ACL) injuries commonly occur during landing maneuvers. Prophylactic knee braces were introduced to reduce the risk of ACL injuries, but their effectiveness is debated.<h4>Hypotheses</h4>We hypothesized that bracing would improve biomechanical factors previously related to the risk of ACL injuries, such as increased hip and knee flexion angles ... Read more >>

Am J Sports Med (The American journal of sports medicine)
[2016, 44(7):1753-1761]

Cited: 5 times

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A cruciate suture technique for rotator cuff repair.

Jonathon Caldow, Martin Richardson, Subash Balakrishnan, Tony Sobol, Peter V S Lee, David C Ackland,

<h4>Purpose</h4>Re-establishment of the native footprint during rotator cuff repair is important for maximizing healing potential and fixation strength. The purpose of this study was to evaluate the contact area, contact pressure, stiffness and tensile strength of a new single-row cruciate suture repair and to compare these results to those of ... Read more >>

Knee Surg Sports Traumatol Arthrosc (Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA)
[2015, 23(2):619-626]

Cited: 2 times

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Compressive fatigue life of subchondral bone of the metacarpal condyle in thoroughbred racehorses.

Sandra Martig, Peter V S Lee, Garry A Anderson, R Chris Whitton,

In racehorses, fatigue related subchondral bone injury leads to overt fracture or articular surface collapse and subsequent articular cartilage degeneration. We hypothesised that the fatigue behaviour of equine subchondral bone in compression follows a power law function similar to that observed in cortical and trabecular bone. We determined the fatigue ... Read more >>

Bone (Bone)
[2013, 57(2):392-398]

Cited: 4 times

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Transforming growth factor-β-induced differentiation of airway smooth muscle cells is inhibited by fibroblast growth factor-2.

Michael Schuliga, Aqeel Javeed, Trudi Harris, Yuxiu Xia, Chengxue Qin, Zhexing Wang, Xuehua Zhang, Peter V S Lee, Blanca Camoretti-Mercado, Alastair G Stewart,

In asthma, basic fibroblast growth factor (FGF-2) plays an important (patho)physiological role. This study examines the effects of FGF-2 on the transforming growth factor-β (TGF-β)-stimulated differentiation of airway smooth muscle (ASM) cells in vitro. The differentiation of human ASM cells after incubation with TGF-β (100 pM) and/or FGF-2 (300 pM) ... Read more >>

Am J Respir Cell Mol Biol (American journal of respiratory cell and molecular biology)
[2013, 48(3):346-353]

Cited: 29 times

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Inhibition of anterior tibial translation or axial tibial rotation prevents anterior cruciate ligament failure during impact compression.

Chen Hua Yeow, Shahbaz Khan Rubab, Peter V S Lee, James C H Goh,

<h4>Background</h4>Anterior cruciate ligament injury is prevalent in activities involving large and rapid landing impact loads.<h4>Hypothesis</h4>Inhibition of anterior tibial translation/axial tibial rotation forestalls the ligament from failing at the range of peak compressive load that can induce ligament failure when both factors are unrestrained.<h4>Study design</h4>Controlled laboratory study.<h4>Methods</h4>Sixteen porcine knee specimens were ... Read more >>

Am J Sports Med (The American journal of sports medicine)
[2009, 37(4):813-821]

Cited: 6 times

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Regression relationships of landing height with ground reaction forces, knee flexion angles, angular velocities and joint powers during double-leg landing.

C H Yeow, Peter V S Lee, James C H Goh,

Ground reaction forces (GRF), knee flexion angles, angular velocities and joint powers are unknown at large landing heights, which are infeasible for laboratory testing. However, this information is important for understanding lower extremity injury mechanisms. We sought to determine regression relationships of landing height with these parameters during landing so ... Read more >>

Knee (The Knee)
[2009, 16(5):381-386]

Cited: 20 times

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