Full Text Journal Articles by
Author Peter F Rebeiro

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Estimating a set of mortality risk functions with multiple contributing causes of death.

Tiffany L Breger, Jessie K Edwards, Stephen R Cole, Michael Saag, Peter F Rebeiro, Richard D Moore, Joseph J Eron,

INTRODUCTION:There are few methodologic examples of how multiple causes of death may be summarized in cause-specific mortality analyses to address limitations of attributing death to a single underlying cause. We propose a cause-of-death weighting approach to estimate the set of risk functions of specific causes of mortality using both underlying ... Read more >>

Epidemiology (Epidemiology (Cambridge, Mass.))
[2020, :]

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Knowledge and stigma of latent tuberculosis infection in Brazil: implications for tuberculosis prevention strategies.

Peter F Rebeiro, Mollie J Cohen, Heather M Ewing, Marina Cruvinel Figueiredo, Lauren Saag Peetluk, Kleydson B Andrade, Marshall Eakin, Elizabeth J Zechmeister, Timothy R Sterling,

BACKGROUND:Tuberculosis (TB) elimination requires treatment of millions of persons with latent M. tuberculosis infection (LTBI). LTBI treatment acceptance depends on population-wide TB knowledge and low stigma, but limited data are available on the relationship between stigma and knowledge. We assessed knowledge of TB disease and LTBI throughout Brazil and examined ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):897]

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The Population Impact of Late Presentation With Advanced HIV Disease and Delayed Antiretroviral Therapy in Adults Receiving HIV Care in Latin America.

Pablo F Belaunzarán-Zamudio, Yanink N Caro-Vega, Bryan E Shepherd, Peter F Rebeiro, Brenda E Crabtree-Ramírez, Claudia P Cortes, Beatriz Grinsztejn, Eduardo Gotuzzo, Fernando Mejia, Denis Padgett, Jean W Pape, Vanessa Rouzier, Valdilea Veloso, Sandra Wagner Cardoso, Catherine C McGowan, Juan G Sierra-Madero, ,

Late presentation to care and antiretroviral therapy (ART) initiation with advanced human immunodeficiency virus (HIV) disease are common in Latin America. We estimated the impact of these conditions on mortality in the region. We included adults enrolled during 2001-2014 at HIV care clinics. We estimated the adjusted attributable risk (AR) ... Read more >>

Am. J. Epidemiol. (American journal of epidemiology)
[2020, 189(6):564-572]

Cited: 1 time

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Resistance-conferring mutations on whole-genome sequencing of fluoroquinolone-resistant and -susceptible M. tuberculosis isolates: a proposed threshold for identifying resistance.

Fernanda Maruri, Yan Guo, Amondrea Blackman, Yuri F van der Heijden, Peter F Rebeiro, Timothy R Sterling,

BACKGROUND:Fluoroquinolone resistance in Mycobacterium tuberculosis is conferred by DNA gyrase mutations, but not all fluoroquinolone-resistant M. tuberculosis isolates have mutations detected. The optimal allele frequency threshold to identify resistance-conferring mutations by whole-genome sequencing is unknown. METHODS:Phenotypically ofloxacin-resistant and lineage-matched ofloxacin-susceptible M. tuberculosis isolates underwent whole-genome sequencing at an average coverage ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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RE: Role of rapid diagnostics for viral respiratory infections in antibiotic prescribing decision in the emergency department, by Li et al (2019).

Danielle A Rankin, Peter F Rebeiro, Zaid Haddadin, Natasha B Halasa, Robert A Greevy,

Infect Control Hosp Epidemiol (Infection control and hospital epidemiology)
[2020, 41(8):991-992]

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Mood Disorders and Increased Risk of Noncommunicable Disease in Adults With HIV.

Jessica L Castilho, Peter F Rebeiro, Bryan E Shepherd, Robertson Nash, Rodney S Adams, Megan Turner, Sally S Furukawa, Todd Hulgan, John R Koethe, Timothy R Sterling,

BACKGROUND:People living with HIV (PLWH) experience high rates of mood disorders (major depression and bipolar affective disorder) which in the general population have been associated with noncommunicable disease (NCD) risk. We examined whether prevalent mood disorders are associated with incident NCDs and multimorbidity (accumulation of ≥2 NCDs) in PLWH. SETTING:Adult ... Read more >>

J. Acquir. Immune Defic. Syndr. (Journal of acquired immune deficiency syndromes (1999))
[2020, 83(4):397-404]

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Lack of Weight Gain During the First 2 Months of Treatment and Human Immunodeficiency Virus Independently Predict Unsuccessful Treatment Outcomes in Tuberculosis.

Lauren S Peetluk, Peter F Rebeiro, Marcelo Cordeiro-Santos, Afranio Kritski, Bruno B Andrade, Betina Durovni, Solange Calvacante, María B Arriaga, Megan M Turner, Marina C Figueiredo, Valeria C Rolla, Timothy R Sterling,

BACKGROUND:Weight change may inform tuberculosis treatment response, but its predictive power may be confounded by human immunodeficiency virus (HIV). METHODS:We prospectively followed up adults with culture-confirmed, drug-susceptible, pulmonary tuberculosis receiving standard 4-drug therapy (isoniazid, rifampin, pyrazinamide, and ethambutol) in Brazil. We examined median weight change 2 months after treatment initiation ... Read more >>

J. Infect. Dis. (The Journal of infectious diseases)
[2020, 221(9):1416-1424]

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Weight gain among treatment-naïve persons with HIV starting integrase inhibitors compared to non-nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in the United States and Canada.

Kassem Bourgi, Cathy A Jenkins, Peter F Rebeiro, Frank Palella, Richard D Moore, Keri N Altoff, John Gill, Charles S Rabkin, Stephen J Gange, Michael A Horberg, Joseph Margolick, Jun Li, Cherise Wong, Amanda Willig, Viviane D Lima, Heidi Crane, Jennifer Thorne, Michael Silverberg, Gregory Kirk, William C Mathews, Timothy R Sterling, Jordan Lake, John R Koethe, ,

INTRODUCTION:Weight gain following antiretroviral therapy (ART) initiation is common, potentially predisposing some persons with HIV (PWH) to cardio-metabolic disease. We assessed relationships between ART drug class and weight change among treatment-naïve PWH initiating ART in the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). METHODS:Adult, treatment-naïve PWH in ... Read more >>

J Int AIDS Soc (Journal of the International AIDS Society)
[2020, 23(4):e25484]

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Greater Weight Gain in Treatment-naive Persons Starting Dolutegravir-based Antiretroviral Therapy.

Kassem Bourgi, Peter F Rebeiro, Megan Turner, Jessica L Castilho, Todd Hulgan, Stephen P Raffanti, John R Koethe, Timothy R Sterling,

BACKGROUND:Recent studies have reported weight gain in virologically suppressed persons living with human immunodeficiency virus (PLWH) switched from older antiretroviral therapy (ART) to newer integrase strand transfer inhibitor (INSTI)-based regimens. In this study, we investigated whether weight gain differs among treatment-naive PLWH starting INSTI-based regimens compared to other ART regimens. ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(7):1267-1274]

Cited: 7 times

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Characterizing the Human Immunodeficiency Virus Care Continuum Among Transgender Women and Cisgender Women and Men in Clinical Care: A Retrospective Time-series Analysis.

Tonia Poteat, David B Hanna, Peter F Rebeiro, Marina Klein, Michael J Silverberg, Joseph J Eron, Michael A Horberg, Mari M Kitahata, W C Mathews, Kristin Mattocks, Angel Mayor, Ashleigh J Rich, Sari Reisner, Jennifer Thorne, Richard D Moore, Yuezhou Jing, Keri N Althoff,

BACKGROUND:Prior studies suggest that transgender women (TW) with human immunodeficiency virus (HIV) are less likely to be virally suppressed than cisgender women (CW) and cisgender men (CM). However, prior data are limited by small sample sizes and cross-sectional designs. We sought to characterize the HIV care continuum comparing TW to ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(6):1131-1138]

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The impact of data quality and source data verification on epidemiologic inference: a practical application using HIV observational data.

Mark J Giganti, Bryan E Shepherd, Yanink Caro-Vega, Paula M Luz, Peter F Rebeiro, Marcelle Maia, Gaetane Julmiste, Claudia Cortes, Catherine C McGowan, Stephany N Duda,

BACKGROUND:Data audits are often evaluated soon after completion, even though the identification of systematic issues may lead to additional data quality improvements in the future. In this study, we assess the impact of the entire data audit process on subsequent statistical analyses. METHODS:We conducted on-site audits of datasets from nine ... Read more >>

BMC Public Health (BMC public health)
[2019, 19(1):1748]

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Temporal changes in ART initiation in adults with high CD4 counts in Latin America: a cohort study.

Brenda E Crabtree-Ramírez, Yanink Caro-Vega, Pablo F Belaunzarán-Zamudio, Bryan E Shepherd, Peter F Rebeiro, Valdilea Veloso, Claudia P Cortes, Denis Padgett, Eduardo Gotuzzo, Juan Sierra-Madero, Catherine C McGowan, Anna K Person, ,

INTRODUCTION:In 2013, the World Health Organization (WHO) recommended initiating combination ART (cART) in all adults with HIV and CD4+ lymphocyte counts (CD4) <500 cells/mm3 . In 2015, this was updated to recommend cART initiation in all patients with HIV, regardless of CD4 count. Implementation of these guidelines in real-world settings has ... Read more >>

J Int AIDS Soc (Journal of the International AIDS Society)
[2019, 22(12):e25413]

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LB9. The Effect of Initiating Integrase Inhibitor-based vs. Non-Nucleoside Reverse Transcriptase Inhibitor-based Antiretroviral Therapy on Progression to Diabetes among North American Persons in HIV Care.

Peter F Rebeiro, Peter F Rebeiro, Cathy Jenkins, Aihua Bian, Jordan Lake, Jordan Lake, Kassem Bourgi, Kassem Bourgi, Michael A Horberg, Michael A Horberg, Richard Moore, Richard Moore, Keri Altoff, Marina Klein, Joseph J Eron, Joseph J Eron, M John Gill, Mari Kitahata, Sonia Napravnik, Michael Silverberg, Angel M Mayor, Amanda Willig, Amanda Willig, Michelle Floris-Moore, Timothy Sterling, John R Koethe, John R Koethe,

AbstractBackgroundIntegrase strand transfer inhibitor (INSTI)-based antiretroviral therapy (ART) has been implicated in greater weight gain than other regimens among people with HIV, but there is little evidence about its role in serious clinical outcomes proximal to weight gain. We therefore examined the impact of initial ART regimen class/drug on incident ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S996-S997]

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Global variations in mortality in adults after initiating antiretroviral treatment: an updated analysis of the International epidemiology Databases to Evaluate AIDS cohort collaboration.

Leigh F Johnson, Nanina Anderegg, Elizabeth Zaniewski, Jeffrey W Eaton, Peter F Rebeiro, Gabriela Carriquiry, Denis Nash, Marcel Yotebieng, Didier K Ekouevi, Charles B Holmes, Jun Y Choi, Awachana Jiamsakul, Giorgos Bakoyannis, Keri N Althoff, Annette H Sohn, Constantin Yiannoutsos, Matthias Egger, ,

BACKGROUND:UNAIDS models use data from the International epidemiology Databases to Evaluate AIDS (IeDEA) collaboration in setting assumptions about mortality rates after antiretroviral treatment (ART) initiation. This study aims to update these assumptions with new data, to quantify the extent of regional variation in ART mortality and to assess trends in ... Read more >>

AIDS (AIDS (London, England))
[2019, 33 Suppl 3:S283-S294]

Cited: 2 times

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Clinic-Level Factors Associated with Retention in Care among People Living with HIV in a Multi-Site United States Cohort, 2010-2016.

Cassandra D Oliver, Peter F Rebeiro, Bryan E Shepherd, Jeanne Keruly, Kenneth H Mayer, W Christopher Mathews, Bulent Turan, Richard D Moore, Heidi M Crane, Elvin Geng, Sonia Napravnik, Mari M Kitahata, Michael J Mugavero, April C Pettit, ,

BACKGROUND:Retention in care (RIC) leads to reduced HIV transmission and mortality. Few studies have investigated the availability of clinic services and RIC among people living with HIV (PLWH) in the United States (US). We conducted a multi-site retrospective cohort study to identify clinic services associated with RIC from 2010-2016 in ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2019, :]

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Life-Expectancy Disparities Among Adults With HIV in the United States and Canada: The Impact of a Reduction in Drug- and Alcohol-Related Deaths Using the Lives Saved Simulation Model.

Keri N Althoff, Aruna Chandran, Jinbing Zhang, Wendy Miranda Arevalo, Stephen J Gange, Timothy R Sterling, M John Gill, Amy C Justice, Frank J Palella, Peter F Rebeiro, Michael J Silverberg, Angel M Mayor, Michael A Horberg, Jennifer E Thorne, Charles S Rabkin, W Christopher Mathews, Marina B Klein, Elizabeth Humes, Jennifer Lee, Robert Hogg, Richard D Moore, ,

Improvements in life expectancy among people living with human immunodeficiency virus (PLWH) receiving antiretroviral treatment in the United States and Canada might differ among key populations. Given the difference in substance use among key populations and the current opioid epidemic, drug- and alcohol-related deaths might be contributing to the disparities ... Read more >>

Am. J. Epidemiol. (American journal of epidemiology)
[2019, 188(12):2097-2109]

Cited: 0 times

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Methodologic Considerations for Small Cohort Studies.

Rany Octaria, Peter F Rebeiro, Marion A Kainer,

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2019, 69(9):1644]

Cited: 0 times

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Temporal Trends and Sociodemographic Correlates of PrEP Uptake in Tennessee, 2017.

Meredith L Brantley, Peter F Rebeiro, April C Pettit, Allison Sanders, Lyle Cooper, Shanell McGoy, Melissa Morrison,

Client-level data from two Tennessee-based PrEP navigation demonstration projects reported to the Tennessee Department of Health from January to December 2017 were evaluated to determine the proportion of clients who accepted, were linked to, and were prescribed PrEP. Disparities by age, race, transmission risk, and geographic region as well as ... Read more >>

AIDS Behav (AIDS and behavior)
[2019, 23(Suppl 3):304-312]

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Diagnosis and clinical outcomes of extrapulmonary tuberculosis in antiretroviral therapy programmes in low- and middle-income countries: a multicohort study.

Kathrin Zürcher, Marie Ballif, Sasisopin Kiertiburanakul, Henri Chenal, Marcel Yotebieng, Beatriz Grinsztejn, Denna Michael, Timothy R Sterling, Kapella M Ngonyani, Anna M Mandalakas, Matthias Egger, April C Pettit, Lukas Fenner, ,

INTRODUCTION:Extrapulmonary tuberculosis (EPTB) is difficult to confirm bacteriologically and requires specific diagnostic capacities. Diagnosis can be especially challenging in under-resourced settings. We studied diagnostic modalities and clinical outcomes of EPTB compared to pulmonary tuberculosis (PTB) among HIV-positive adults in antiretroviral therapy (ART) programmes in low- and middle-income countries (LMIC). METHODS:We ... Read more >>

J Int AIDS Soc (Journal of the International AIDS Society)
[2019, 22(9):e25392]

Cited: 3 times

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Human Immunodeficiency Virus (HIV) Viral Suppression After Transition From Having No Healthcare Coverage and Relying on Ryan White HIV/AIDS Program Support to Medicaid or Private Health Insurance.

Julia Raifman, Keri Althoff, Peter F Rebeiro, W Christopher Mathews, Laura W Cheever, Heather Hauck, Judith A Aberg, Kelly A Gebo, Richard Moore, Stephen A Berry, ,

Among 1942 persons with human immunodeficiency virus (HIV) without healthcare coverage in 2012-2015, transitioning to Medicaid (adjusted prevalence ratio, 0.95 [0.87, 1.04]) or to private health insurance (1.04 [0.95, 1.13]) was not associated with a change in consistent HIV viral suppression compared to continued reliance on the Ryan White HIV/AIDS ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2019, 69(3):538-541]

Cited: 0 times

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Trends and Disparities in Mortality and Progression to AIDS in the Highly Active Antiretroviral Therapy Era: Tennessee, 1996-2016.

Peter F Rebeiro, April C Pettit, Lindsey Sizemore, Samantha A Mathieson, Carolyn Wester, Aaron Kipp, Bryan E Shepherd, Timothy R Sterling,

Objectives. To use statewide surveillance data to examine trends and disparities in mortality and progression from HIV to AIDS comprehensively in Tennessee over the past 20 years.Methods. Individuals diagnosed with HIV in Tennessee from 1996 to 2016 were identified through the Tennessee Department of Health Enhanced HIV/AIDS Reporting System. Clinical ... Read more >>

Am J Public Health (American journal of public health)
[2019, 109(9):1266-1272]

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Changes in rapid HIV treatment initiation after national "treat all" policy adoption in 6 sub-Saharan African countries: Regression discontinuity analysis.

Olga Tymejczyk, Ellen Brazier, Constantin T Yiannoutsos, Michael Vinikoor, Monique van Lettow, Fred Nalugoda, Mark Urassa, Jean d'Amour Sinayobye, Peter F Rebeiro, Kara Wools-Kaloustian, Mary-Ann Davies, Elizabeth Zaniewski, Nanina Anderegg, Grace Liu, Nathan Ford, Denis Nash, ,

BACKGROUND:Most countries have formally adopted the World Health Organization's 2015 recommendation of universal HIV treatment ("treat all"). However, there are few rigorous assessments of the real-world impact of treat all policies on antiretroviral treatment (ART) uptake across different contexts. METHODS AND FINDINGS:We used longitudinal data for 814,603 patients enrolling in ... Read more >>

PLoS Med. (PLoS medicine)
[2019, 16(6):e1002822]

Cited: 6 times

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On the assessment of trend in CD4+ cell count and viral suppression after transition to adult care.

Cassandra Oliver, Peter F Rebeiro, April C Pettit,

AIDS (AIDS (London, England))
[2019, 33(9):1536-1537]

Cited: 0 times

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Increased vitamin D receptor expression from macrophages after stimulation with M. tuberculosis among persons who have recovered from extrapulmonary tuberculosis.

Christina T Fiske, Amondrea Blackman, Fernanda Maruri, Peter F Rebeiro, Moises Huaman, Jamie Kator, Holly M Scott Algood, Timothy R Sterling,

BACKGROUND:Independent of HIV infection, extrapulmonary TB (EPTB) risk is increased in women, persons of black race or foreign birth, and by genetic variants in vitamin D receptor (VDR), interleukin-1 beta (IL-1β), and toll-like receptor (TLR)-2; functional correlates are unclear. We evaluated macrophage expression of VDR, TLR2, cathelicidin, and TNF-α, and ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2019, 19(1):366]

Cited: 1 time

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Substance Use, Demographic and Socioeconomic Factors Are Independently Associated With Postpartum HIV Care Engagement in the Southern United States, 1999-2016.

Cassandra Oliver, Peter F Rebeiro, Mary J Hopkins, Beverly Byram, Lavenia Carpenter, Kate Clouse, Jessica L Castilho, William Rogers, Megan Turner, Sally S Bebawy, April C Pettit,

Background:Retention in care (RIC) and viral suppression (VS) are associated with reduced HIV transmission and mortality. Studies addressing postpartum engagement in HIV care have been limited by small sample size, short follow-up, and a lack of data from the Southeast United States. Methods:HIV-positive adult women with ≥1 prenatal visit at ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(2):ofz023]

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