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Author Pedro Marques Vidal

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Preoperative Clinical Factors Associated with Short-Stay Laparoscopic Appendectomy.

Aurélie Vuagniaux, Olivier Gié, Fabio Butti, Pedro Manuel Marques-Vidal, Nicolas Demartines, Styliani Mantziari,

BACKGROUND:Outpatient appendectomy for acute appendicitis is a feasible, yet not widely performed procedure, as there are no universally accepted criteria for patient selection. The aim of this study was to assess preoperative clinical factors associated with successful short-stay appendectomy (SSA) and establish a predictive score to help with patient selection. ... Read more >>

World J Surg (World journal of surgery)
[2019, :]

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The Metabolic Benefits of Menopausal Hormone Therapy Are Not Mediated by Improved Nutritional Habits. The OsteoLaus Cohort.

Georgios E Papadakis, Didier Hans, Elena Gonzalez Rodriguez, Peter Vollenweider, Gerard Waeber, Pedro Marques-Vidal, Olivier Lamy,

Menopause alters body composition by increasing fat mass. Menopausal hormone therapy (MHT) is associated with decreased total and visceral adiposity. It is unclear whether MHT favorably affects energy intake. We aimed to assess in the OsteoLaus cohort whether total energy intake (TEI) and/or diet quality (macro- and micronutrients, dietary patterns, ... Read more >>

Nutrients (Nutrients)
[2019, 11(8):]

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National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries.

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BACKGROUND:Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to compare trends in total, HDL and non-HDL cholesterol and the total-to-HDL cholesterol ratio in Asian and Western countries. METHODS:We pooled 458 population-based ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2019, :]

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The Contribution of Diet Quality to Socioeconomic Inequalities in Obesity: A Population-based Study of Swiss Adults.

Carlos de Mestral, Angeline Chatelan, Pedro Marques-Vidal, Silvia Stringhini, Murielle Bochud,

Socioeconomically disadvantaged people are disproportionally more likely to develop obesity and obesity-related diseases. However, it remains unclear to what extent diet quality contributes to socioeconomic inequalities in obesity. We aimed to assess the role of diet quality in the association between socioeconomic status (SES) and obesity. Data originated from the ... Read more >>

Nutrients (Nutrients)
[2019, 11(7):]

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Dietary Factors and Modulation of Bacteria Strains of Akkermansia muciniphila and Faecalibacterium prausnitzii: A Systematic Review.

Sanne Verhoog, Petek Eylul Taneri, Zayne M Roa Díaz, Pedro Marques-Vidal, John P Troup, Lia Bally, Oscar H Franco, Marija Glisic, Taulant Muka,

Akkermansia muciniphila and Faecalibacterium prausnitzii are highly abundant human gut microbes in healthy individuals, and reduced levels are associated with inflammation and alterations of metabolic processes involved in the development of type 2 diabetes. Dietary factors can influence the abundance of A. muciniphila and F. prausnitzii, but the evidence is ... Read more >>

Nutrients (Nutrients)
[2019, 11(7):]

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Salivary cortisol is not associated with incident insulin resistance or type 2 diabetes mellitus.

Karim Gariani, Pedro Marques-Vidal, Gérard Waeber, Peter Vollenweider, François Jornayvaz,

BACKGROUND:Excessive glucocorticoid secretion has been associated with type 2 diabetes mellitus (T2DM) and other features of the metabolic syndrome. We aimed to evaluate if basal salivary cortisol may predict occurrence of new insulin resistance (IR) or T2DM. METHOD:This was a prospective, population-based study derived from the CoLaus (Cohorte lausannoise) study ... Read more >>

Endocr Connect (Endocrine connections)
[2019, :]

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Patterns of multimorbidity in internal medicine patients in Swiss university hospitals: a multicentre cohort study.

Carole E Aubert, Niklaus Fankhauser, Pedro Marques-Vidal, Jérôme Stirnemann, Drahomir Aujesky, Andreas Limacher, Jacques Donzé,

AIMS OF THE STUDY:Despite the high prevalence of multimorbidity, we lack detailed descriptive data on the most prevalent combinations of chronic comorbidities in Switzerland. We aimed to describe and quantify the most prevalent combinations of comorbidities in internal medicine multimorbid inpatients. METHODS:We conducted a multicentre retrospective cohort study including all ... Read more >>

Swiss Med Wkly (Swiss medical weekly)
[2019, 149:w20094]

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Alcohol control policies and socioeconomic inequalities in hazardous alcohol consumption: a 22-year cross-sectional study in a Swiss urban population.

José Luis Sandoval, Teresa Leão, Jean-Marc Theler, Thierry Favrod-Coune, Barbara Broers, Jean-Michel Gaspoz, Pedro Marques-Vidal, Idris Guessous,

OBJECTIVE:Harmful use of alcohol represents a large socioeconomic and disease burden and displays a socioeconomic status (SES) gradient. Several alcohol control laws were devised and implemented, but their equity impact remains undetermined.We ascertained if an SES gradient in hazardous alcohol consumption exists in Geneva (Switzerland) and assessed the equity impact ... Read more >>

BMJ Open (BMJ open)
[2019, 9(5):e028971]

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Association of Positive Airway Pressure Prescription With Mortality in Patients With Obesity and Severe Obstructive Sleep Apnea: The Sleep Heart Health Study.

Quentin Lisan, Thomas Van Sloten, Pedro Marques Vidal, Jose Haba Rubio, Raphael Heinzer, Jean Philippe Empana,

Importance:The association of positive airway pressure (PAP) with reduced mortality in patients with obstructive sleep apnea (OSA) remains uncertain. Objective:To investigate the association between PAP prescription and mortality. Design, Setting, and Participants:This multicenter, population-based cohort study evaluated data from the Sleep Heart Health Study (SHHS), a long-term observational cohort study ... Read more >>

JAMA Otolaryngol Head Neck Surg (JAMA otolaryngology-- head & neck surgery)
[2019, 145(6):509-515]

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Patterns of multimorbidity associated with 30-day readmission: a multinational study.

Carole E Aubert, Jeffrey L Schnipper, Niklaus Fankhauser, Pedro Marques-Vidal, Jérôme Stirnemann, Andrew D Auerbach, Eyal Zimlichman, Sunil Kripalani, Eduard E Vasilevskis, Edmondo Robinson, Joshua Metlay, Grant S Fletcher, Andreas Limacher, Jacques Donzé,

BACKGROUND:Multimorbidity is associated with higher healthcare utilization; however, data exploring its association with readmission are scarce. We aimed to investigate which most important patterns of multimorbidity are associated with 30-day readmission. METHODS:We used a multinational retrospective cohort of 126,828 medical inpatients with multimorbidity defined as ≥2 chronic diseases. The primary ... Read more >>

BMC Public Health (BMC public health)
[2019, 19(1):738]

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Does sleep affect weight gain? Assessing subjective sleep and polysomnography measures in a population-based cohort study (CoLaus/HypnoLaus).

Nadine Häusler, Raphaël Heinzer, Jose Haba-Rubio, Pedro Marques-Vidal,

STUDY OBJECTIVES:Although several studies have linked short and long sleep duration to weight gain, mixed results exist. Contrarily, few studies associated objectively measured sleep characteristics with weight gain. We investigated the association between several sleep characteristics measured by questionnaire and polysomnography with prospective weight gain in a population-based, middle-aged cohort. ... Read more >>

Sleep (Sleep)
[2019, 42(6):]

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Rising rural body-mass index is the main driver of the global obesity epidemic in adults.

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Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity3-6. Here we use ... Read more >>

Nature (Nature)
[2019, 569(7755):260-264]

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Does sleep predict next-day napping or does napping influence same-day nocturnal sleep? Results of a population-based ecological momentary assessment study.

Nadine Häusler, Pedro Marques-Vidal, José Haba-Rubio, Raphael Heinzer,

STUDY OBJECTIVES:The temporal relationship between nocturnal sleep and daytime napping has only been assessed in small non-representative samples, and suggests that nocturnal sleep and napping are interdependent, although mixed results exist. In this study, we investigated the temporal relationship between nocturnal sleep and napping (and vice versa). METHODS:A population-based sample ... Read more >>

Sleep Med. (Sleep medicine)
[2019, :]

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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Nicole M Warrington, Robin N Beaumont, Momoko Horikoshi, Felix R Day, Øyvind Helgeland, Charles Laurin, Jonas Bacelis, Shouneng Peng, Ke Hao, Bjarke Feenstra, Andrew R Wood, Anubha Mahajan, Jessica Tyrrell, Neil R Robertson, N William Rayner, Zhen Qiao, Gunn-Helen Moen, Marc Vaudel, Carmen J Marsit, Jia Chen, Michael Nodzenski, Theresia M Schnurr, Mohammad H Zafarmand, Jonathan P Bradfield, Niels Grarup, Marjolein N Kooijman, Ruifang Li-Gao, Frank Geller, Tarunveer S Ahluwalia, Lavinia Paternoster, Rico Rueedi, Ville Huikari, Jouke-Jan Hottenga, Leo-Pekka Lyytikäinen, Alana Cavadino, Sarah Metrustry, Diana L Cousminer, Ying Wu, Elisabeth Thiering, Carol A Wang, Christian T Have, Natalia Vilor-Tejedor, Peter K Joshi, Jodie N Painter, Ioanna Ntalla, Ronny Myhre, Niina Pitkänen, Elisabeth M van Leeuwen, Raimo Joro, Vasiliki Lagou, Rebecca C Richmond, Ana Espinosa, Sheila J Barton, Hazel M Inskip, John W Holloway, Loreto Santa-Marina, Xavier Estivill, Wei Ang, Julie A Marsh, Christoph Reichetzeder, Letizia Marullo, Berthold Hocher, Kathryn L Lunetta, Joanne M Murabito, Caroline L Relton, Manolis Kogevinas, Leda Chatzi, Catherine Allard, Luigi Bouchard, Marie-France Hivert, Ge Zhang, Louis J Muglia, Jani Heikkinen, , Camilla S Morgen, Antoine H C van Kampen, Barbera D C van Schaik, Frank D Mentch, Claudia Langenberg, Jian'an Luan, Robert A Scott, Jing Hua Zhao, Gibran Hemani, Susan M Ring, Amanda J Bennett, Kyle J Gaulton, Juan Fernandez-Tajes, Natalie R van Zuydam, Carolina Medina-Gomez, Hugoline G de Haan, Frits R Rosendaal, Zoltán Kutalik, Pedro Marques-Vidal, Shikta Das, Gonneke Willemsen, Hamdi Mbarek, Martina Müller-Nurasyid, Marie Standl, Emil V R Appel, Cilius E Fonvig, Caecilie Trier, Catharina E M van Beijsterveldt, Mario Murcia, Mariona Bustamante, Sílvia Bonas-Guarch, David M Hougaard, Josep M Mercader, Allan Linneberg, Katharina E Schraut, Penelope A Lind, Sarah E Medland, Beverley M Shields, Bridget A Knight, Jin-Fang Chai, Kalliope Panoutsopoulou, Meike Bartels, Friman Sánchez, Jakob Stokholm, David Torrents, Rebecca K Vinding, Sara M Willems, Mustafa Atalay, Bo L Chawes, Peter Kovacs, Inga Prokopenko, Marcus A Tuke, Hanieh Yaghootkar, Katherine S Ruth, Samuel E Jones, Po-Ru Loh, Anna Murray, Michael N Weedon, Anke Tönjes, Michael Stumvoll, Kim F Michaelsen, Aino-Maija Eloranta, Timo A Lakka, Cornelia M van Duijn, Wieland Kiess, Antje Körner, Harri Niinikoski, Katja Pahkala, Olli T Raitakari, Bo Jacobsson, Eleftheria Zeggini, George V Dedoussis, Yik-Ying Teo, Seang-Mei Saw, Grant W Montgomery, Harry Campbell, James F Wilson, Tanja G M Vrijkotte, Martine Vrijheid, Eco J C N de Geus, M Geoffrey Hayes, Haja N Kadarmideen, Jens-Christian Holm, Lawrence J Beilin, Craig E Pennell, Joachim Heinrich, Linda S Adair, Judith B Borja, Karen L Mohlke, Johan G Eriksson, Elisabeth E Widén, Andrew T Hattersley, Tim D Spector, Mika Kähönen, Jorma S Viikari, Terho Lehtimäki, Dorret I Boomsma, Sylvain Sebert, Peter Vollenweider, Thorkild I A Sørensen, Hans Bisgaard, Klaus Bønnelykke, Jeffrey C Murray, Mads Melbye, Ellen A Nohr, Dennis O Mook-Kanamori, Fernando Rivadeneira, Albert Hofman, Janine F Felix, Vincent W V Jaddoe, Torben Hansen, Charlotta Pisinger, Allan A Vaag, Oluf Pedersen, André G Uitterlinden, Marjo-Riitta Järvelin, Christine Power, Elina Hyppönen, Denise M Scholtens, William L Lowe, George Davey Smith, Nicholas J Timpson, Andrew P Morris, Nicholas J Wareham, Hakon Hakonarson, Struan F A Grant, Timothy M Frayling, Debbie A Lawlor, Pål R Njølstad, Stefan Johansson, Ken K Ong, Mark I McCarthy, John R B Perry, David M Evans, Rachel M Freathy,

Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). ... Read more >>

Nat. Genet. (Nature genetics)
[2019, 51(5):804-814]

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Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour.

Samuel E Jones, Vincent T van Hees, Diego R Mazzotti, Pedro Marques-Vidal, Séverine Sabia, Ashley van der Spek, Hassan S Dashti, Jorgen Engmann, Desana Kocevska, Jessica Tyrrell, Robin N Beaumont, Melvyn Hillsdon, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Seth A Sharp, Yingjie Ji, Jamie W Harrison, Rachel M Freathy, Anna Murray, Annemarie I Luik, Najaf Amin, Jacqueline M Lane, Richa Saxena, Martin K Rutter, Henning Tiemeier, Zoltán Kutalik, Meena Kumari, Timothy M Frayling, Michael N Weedon, Philip R Gehrman, Andrew R Wood,

Sleep is an essential human function but its regulation is poorly understood. Using accelerometer data from 85,670 UK Biobank participants, we perform a genome-wide association study of 8 derived sleep traits representing sleep quality, quantity and timing, and validate our findings in 5,819 individuals. We identify 47 genetic associations at ... Read more >>

Nat Commun (Nature Communications)
[2019, 10(1):1585]

Cited: 2 times

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Nutritional epidemiology, extinction or evolution? It is all about balance and moderation.

Sanne Verhoog, Pedro Marques-Vidal, Oscar H Franco,

Eur. J. Epidemiol. (European journal of epidemiology)
[2019, 34(4):333-335]

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Cardiovascular health and sleep disturbances in two population-based cohort studies.

Nadine Hausler, Quentin Lisan, Thomas Van Sloten, Jose Haba-Rubio, Marie-Cécile Perier, Frédérique Thomas, Nicolas Danchin, Catherine Guibout, Pierre Boutouyrie, Raphael Heinzer, Xavier Jouven, Pedro Marques-Vidal, Jean-Philippe Empana,

OBJECTIVE:We aimed to investigate the association between cardiovascular health (CVH), as defined by the American Heart Association, and several sleep disturbances. METHODS:Two community-based cohorts, the Paris Prospective Study 3 (PPS3, France, n=6441) and the CoLaus study (Switzerland, n=2989) were analysed. CVH includes 7 metrics which all can be classified as ... Read more >>

Heart (Heart (British Cardiac Society))
[2019, :]

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How Are Sleep Characteristics Related to Cardiovascular Health? Results From the Population-Based HypnoLaus study.

Nadine Häusler, Pedro Marques-Vidal, Raphael Heinzer, José Haba-Rubio,

Background Although sleep characteristics have been linked to cardiovascular disease and cardiovascular risk factors, the association between sleep characteristics measured by polysomnography and cardiovascular health ( CVH ) remains unknown. Methods and Results In a population-based sample (n=1826), sleep characteristics were assessed by both sleep questionnaires and polysomnography. Global, behavioral, ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2019, 8(7):e011372]

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[Menopausal hormone therapy. Effects on bone and body composition].

Georgios Papadakis, Elena Gonzalez Rodriguez, Pedro Marques-Vidal, Didier Hans, Peter Vollenweider, Gérard Waeber, Olivier Lamy,

Changes occurring at menopause can be mitigated by prescribing menopausal hormone replacement therapy (HRT). Recent publications from the CoLaus/OsteoLaus cohorts provide important insights into the effects of HRT and after its discontinuation on bone and body composition. HRT has a beneficial effect on bone mineral density, bone microarchitecture and fracture ... Read more >>

Rev Med Suisse (Revue medicale suisse)
[2019, 15(647):836-839]

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Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry.

Kornelia Kotseva, Guy De Backer, Dirk De Bacquer, Lars Rydén, Arno Hoes, Diederick Grobbee, Aldo Maggioni, Pedro Marques-Vidal, Catriona Jennings, Ana Abreu, Carlos Aguiar, Jolita Badariene, Jan Bruthans, Almudena Castro Conde, Renata Cifkova, Jim Crowley, Kairat Davletov, Jaap Deckers, Delphine De Smedt, Johan De Sutter, Mirza Dilic, Marina Dolzhenko, Vilnis Dzerve, Andrejs Erglis, Zlatko Fras, Dan Gaita, Nina Gotcheva, Peter Heuschmann, Hosam Hasan-Ali, Piotr Jankowski, Nebojsa Lalic, Seppo Lehto, Dragan Lovic, Silvia Mancas, Linda Mellbin, Davor Milicic, Erkin Mirrakhimov, Rafael Oganov, Nana Pogosova, Zeljko Reiner, Stefan Stöerk, Lâle Tokgözoğlu, Costas Tsioufis, Dusko Vulic, David Wood, ,

AIMS:The aim of this study was to determine whether the Joint European Societies guidelines on secondary cardiovascular prevention are followed in everyday practice. DESIGN:A cross-sectional ESC-EORP survey (EUROASPIRE V) at 131 centres in 81 regions in 27 countries. METHODS:Patients (<80 years old) with verified coronary artery events or interventions were ... Read more >>

Eur J Prev Cardiol (European journal of preventive cardiology)
[2019, 26(8):824-835]

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Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity.

Olof S Dallner, Jill M Marinis, Yi-Hsueh Lu, Kivanc Birsoy, Emory Werner, Gulya Fayzikhodjaeva, Brian D Dill, Henrik Molina, Arden Moscati, Zoltán Kutalik, Pedro Marques-Vidal, Tuomas O Kilpeläinen, Niels Grarup, Allan Linneberg, Yinxin Zhang, Roger Vaughan, Ruth J F Loos, Mitchell A Lazar, Jeffrey M Friedman,

Quantitative changes in leptin concentration lead to alterations in food intake and body weight, but the regulatory mechanisms that control leptin gene expression are poorly understood. Here we report that fat-specific and quantitative leptin expression is controlled by redundant cis elements and trans factors interacting with the proximal promoter together ... Read more >>

Nat. Med. (Nature medicine)
[2019, 25(3):507-516]

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Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

Raymond Noordam, Maxime Bos, Heming Wang, Thomas Winkler, Amy Bentley, Tuomas Kilpeläinen, Paul de Vries, Yun Ju Sung, Karen Schwander, Brain Cabe, Alisa Manning, Hugues Aschard, Michael Brown, Han Chen, Nora Franceschini, Solomon Musani, Melissa Richard, Dina Vojinovic, Stella Aslibekyan, Traci Bartz, Lisa de las Fuentes, Mary Feitosa, Andrea Horimoto, Marjan Ilkov, Minjung Kho, Aldi Kraja, Changwei Li, Elise Lim, Yongmei Liu, Dennis Mook-Kanamori, Tuomo Rankinen, Salman Tajuddin, Ashley van der Spek, Zhe Wang, Jonathan Marten, Vincent Laville, Maris Alver, Evangelos Evangelou, Maria Graff, Meian He, Brigitte Kühnel, Leo-Pekka Lyytikäinen, Pedro Marques-Vidal, Ilja Notle, Nicholette Palmer, Rainer Rauramaa, Xiao-Ou Shu, Harold Snieder, Stefan Weiss, Wanqing Wen, Lisa Yanek, Correa Adolfo, Christie Ballentyne, Larry Bielak, Nienke Biermasz, Erik Boerwinkle, Niki Dimou, Gudny Eiriksdottir, Chuan Gao, Sina Gharib, Daniel Gottlieb, José Haba-Rubio, Tamara Harris, Sami Heikkinen, Raphaël Heinzer, James Hixson, Georg Homuth, Arfan Ikram, Pirjo Komulainen, Jose Krieger, Jiwon Lee, Jingmin Liu, Kurt Lohman, Annemarie Luik, Reedik Mägi, Lisa Martin, Thomas Meitinger, Andres Metspalu, Yuri Milaneschi, Mike Nalls, Jeff O'Connell, Annette Peters, Patricia Peyser, Olli Raitakari, Alex Reiner, Patrick CN Rensen, Treva Rice, Stephan Rich, Till Roenneberg, Jerome Rotter, Pamela Schreiner, James Shikany, Stephan Sidney, Mario Sims, Colleen Sitlani, Tamar Sofer, Konstantin Strauch, Morris Swertz, Kent Taylor, André Uitterlinden, Cornelia van Duijn, Henry Völzke, Melanie Waldenberger, Robert Wallance, Ko Willems van Dijk, Caizheng Yu, Alan Zonderman, Diane Becker, Paul Elliott, Tõnu Esko, Christian Gieger, Hans Grabe, Timo Lakka, Terho Lehtimäki, Kari North, Brenda WJH Penninx, Peter Vollenweider, Lynne Wagenknecht, Tangchun Wu, Yong-Bing Xiang, Wei Zheng, Donna Arnett, Claude Bouchard, Michele Evens, Vilmundur Gudnason, Sharon Kardia, Tanika Kelly, Stephen Kritchevsky, Ruth JF Loos, Alexandre Pereira, Mike Province, Bruce Psaty, Charles Rotimi, Xiaofeng Zhu, Najaf Amin, Adrienne Cupples, Myriam Fornage, Ervin Fox, Xiuqing Guo, James Gauderman, Kenneth Rice, Charles Kooperberg, Patricia Munroe, Ching-Ti Liu, Alanna Morrison, Dabeeru Rao, Diana van Heemst, Susan Redline, ,

Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To provide new insights in the biology of sleep-associated adverse lipid profile, we conducted multi-ancestry genome-wide sleep-SNP interaction analyses on three lipid traits (HDL-c, LDL-c and triglycerides). In the total study sample (discovery ... Read more >>

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Association between actigraphy-based sleep duration variability and cardiovascular risk factors - Results of a population-based study.

Nadine Häusler, Pedro Marques-Vidal, José Haba-Rubio, Raphael Heinzer,

BACKGROUND:Although a few studies suggest an adverse effect of sleep duration variability on cardiovascular risk factor, others did not and this association remains controversial. Moreover, most studies were non-representative of the general population, used different sleep duration variability measures, and relied on self-reported sleep duration. We aimed to assess the ... Read more >>

Sleep Med. (Sleep medicine)
[2019, :]

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Effect of Three Hypopnea Scoring Criteria on OSA Prevalence and Associated Comorbidities in the General Population.

Camila Hirotsu, Jose Haba-Rubio, Daniela Andries, Nadia Tobback, Pedro Marques-Vidal, Peter Vollenweider, Gérard Waeber, Raphael Heinzer,

STUDY OBJECTIVES:Apnea-hypopnea index (AHI) is the main polysomnographic measure to diagnose obstructive sleep apnea (OSA). We aimed to evaluate the effect of three standard hypopnea definitions on the prevalence of OSA and its association with cardiometabolic outcomes in the general population. METHODS:We analyzed data from the HypnoLaus study (Lausanne, Switzerland), ... Read more >>

J Clin Sleep Med (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine)
[2019, 15(2):183-194]

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The association between adherence to the Mediterranean diet and hepatic steatosis: cross-sectional analysis of two independent studies, the UK Fenland Study and the Swiss CoLaus Study.

Saman Khalatbari-Soltani, Fumiaki Imamura, Soren Brage, Emanuella De Lucia Rolfe, Simon J Griffin, Nicholas J Wareham, Pedro Marques-Vidal, Nita G Forouhi,

BACKGROUND AND AIMS:The risk of hepatic steatosis may be reduced through changes to dietary intakes, but evidence is sparse, especially for dietary patterns including the Mediterranean diet. We investigated the association between adherence to the Mediterranean diet and prevalence of hepatic steatosis. METHODS:Cross-sectional analysis of data from two population-based adult ... Read more >>

BMC Med (BMC medicine)
[2019, 17(1):19]

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