Full Text Journal Articles by
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Bioactivity of the Protein Hydrolysates Obtained from the Most Abundant Crustacean Bycatch.

Tavani R Camargo, Paulo Mantoan, Patrícia Ramos, José M Monserrat, Carlos Prentice, Célio C Fernandes, Willian F Zambuzzi, Wagner C Valenti,

The animals from bycatch of the shrimp fisheries can be a source of natural products and bioactive compounds. Thus, the present study aimed to evaluate the bioactivity of protein hydrolysates prepared from the two most abundant crabs from the bycatch of shrimp fisheries in Brazil (Callinectes ornatus and Hepatus pudibundus). ... Read more >>

Mar Biotechnol (NY) (Marine biotechnology (New York, N.Y.))
[2021, :]

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Pro-Oxidant Effect of Resveratrol on Human Breast Cancer MCF-7 Cells is Associated with CK2 Inhibition.

Paula Seixas da Costa, Patrícia Severo Ramos, Christian Ferreira, Jerson Lima Silva, Tatiana El-Bacha, Eliane Fialho,

Casein kinase 2 (CK2) plays a critical role in the proliferation and apoptosis of cancer cells. Resveratrol is a bioactive compound with anticancer and anti-inflammatory effects. This study investigated the pro-oxidant cytotoxic effects of resveratrol in association with the inhibition of CK2 activity on human breast carcinoma cells MCF-7. We ... Read more >>

Nutr Cancer (Nutrition and cancer)
[2021, :1-10]

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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

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<h4>Background</h4>Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.<h4>Methods</h4>The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an ... Read more >>

Br J Surg (The British journal of surgery)
[2021, 108(9):1056-1063]

Cited: 15 times

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SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.

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SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We ... Read more >>

Anaesthesia (Anaesthesia)
[2021, :]

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A new mutation in mgrb mediating polymyxin resistance in Klebsiella variicola.

Michael H Lenzi, Willames Mbs Martins, Mélanie Roch, Patrícia L Ramos, Kirsty Sands, Rodrigo Cayô, Timothy R Walsh, Diego O Andrey, Ana C Gales,

Polymyxin resistance is a public health concern - present in humans, animals and the environment - caused by chromosomal-encoding or plasmid-encoding mechanisms. Chromosomal alterations in MgrB are frequently detected in Klebsiella spp., but not yet reported and characterised in Klebsiella variicola (K. variicola). This study performed microbiological and genomic characterisation ... Read more >>

Int J Antimicrob Agents (International journal of antimicrobial agents)
[2021, 58(5):106424]

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Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study.

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We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave ... Read more >>

Anaesthesia (Anaesthesia)
[2021, 76(11):1454-1464]

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Enzymatic diversity of filamentous fungi isolated from forest soil incremented by sugar cane solid waste.

Lidiane M S Lima, Debora N Okamoto, Michel R Z Passarini, Sarah S Gonçalves, Gustavo H Goldman, Marghuel A V Silveira, Patrícia L Ramos, João B Cruz, Maria Juliano, Marcelo F M Marcondes, Suzan P Vasconcellos,

Fungi are natural degraders of organic matter which can produce enzymes for many industrial and biotechnological applications. In this context, crude enzymatic extracts of fungal isolates were evaluated regarding their hydrolytic and ligninolytic abilities. The fungal strains were isolated from soil samples from Atlantic Rain Forest Park incremented with sugar ... Read more >>

Environ Technol (Environmental technology)
[2021, :1-21]

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Activation of cryptic donor splice sites by non-coding and coding PAX6 variants contributes to congenital aniridia.

Maria Tarilonte, Patricia Ramos, Jennifer Moya, Guilermo Fernandez-Sanz, Fiona Blanco-Kelly, Saoud Tahsin Swafiri, Cristina Villaverde, Raquel Romero, Alejandra Tamayo, Blanca Gener, Patrick Calvas, Carmen Ayuso, Marta Corton,

<h4>Background</h4>The paired-domain transcription factor paired box gene 6 (PAX6) causes a wide spectrum of ocular developmental anomalies, including congenital aniridia, Peters anomaly and microphthalmia. Here, we aimed to functionally assess the involvement of seven potentially non-canonical splicing variants on missplicing of exon 6, which represents the main hotspot region for ... Read more >>

J Med Genet (Journal of medical genetics)
[2021, :]

Cited: 1 time

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Reference values for trace element levels in the human brain: A systematic review of the literature.

Patrícia Ramos, Edgar Pinto, Agostinho Santos, Agostinho Almeida,

Some trace elements (TE) are eminently toxic for humans (e.g., Al, Pb, Hg, Cd) and its presence in the central nervous system has been linked to the etiology of neurodegenerative diseases (ND). More recently, the focus has shifted to the potential role of the imbalances on essential TE levels (e.g., ... Read more >>

J Trace Elem Med Biol (Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS))
[2021, 66:126745]

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Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study.

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Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 ... Read more >>

Anaesthesia (Anaesthesia)
[2021, 76(6):748-758]

Cited: 37 times

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Further insights into the eco-epidemiology of American cutaneous leishmaniasis in the Belem metropolitan region, Pará State, Brazil.

Lucas Pantoja Gonçalves, Thiago Vasconcelos Dos Santos, Marliane Batista Campos, Luciana Vieira do Rêgo Lima, Edna Aoba Yassui Ishikawa, Fernando Tobias Silveira, Patrícia Karla Santos Ramos,

<h4>Introduction</h4>In the Belém Metropolitan Region (BMR), Pará State, Brazil, American cutaneous leishmaniasis (ACL) is endemic; however, very little is known regarding its causative agents. Therefore, we used our standard diagnostic approach combined with an RNA polymerase II largest subunit (RNAPOIILS)-polymerase chain reaction (PCR) followed by analysis of restriction fragment length ... Read more >>

Rev Soc Bras Med Trop (Revista da Sociedade Brasileira de Medicina Tropical)
[2020, 53:e20200255]

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Urine qPCR diagnoses over the entire clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infections in the Brazilian Amazon.

Patrícia Karla Santos Ramos, Lucas Pantoja Gonçalves, Ana Camila Oliveira Alves, Samir Mansour Casseb, Luciana Vieira do Rêgo Lima, Marliane Batista Campos, Thiago Vasconcelos Dos Santos, Fernando Tobias Silveira,

The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infections in the Brazilian Amazon has been defined using DTH/IFAT-IgG immune assays and the clinical statuses of infected individuals, revealing five profiles: three asymptomatic [Asymptomatic Infection (AI), Subclinical Resistant Infection (SRI), and Indeterminate Initial Infection (III)], and two symptomatic profiles [Subclinical Oligosymptomatic ... Read more >>

Parasitol Int (Parasitology international)
[2021, 81:102273]

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Effectiveness of virtual reality training in improving knowledge among nursing students: A systematic review, meta-analysis and meta-regression.

Adele Pei Ning Woon, Wen Qi Mok, Ying Jia Shermin Chieng, Hui Min Zhang, Patricia Ramos, Haryani Binte Mustadi, Ying Lau,

<h4>Objectives</h4>We aimed to (1) evaluate the effectiveness of virtual reality (VR) training in improving knowledge among nursing students and (2) identify the essential features of training.<h4>Design</h4>This systematic review was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines.<h4>Data sources</h4>Randomised controlled trials (RCTs) were obtained from PubMed, ... Read more >>

Nurse Educ Today (Nurse education today)
[2021, 98:104655]

Cited: 3 times

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Hypermucoviscous/hypervirulent and extensively drug-resistant QnrB2-, QnrS1-, and CTX-M-3-coproducing Klebsiella pneumoniae ST2121 isolated from an infected elephant (Loxodonta africana).

João Pedro Rueda Furlan, Ralf Lopes, Irys Hany Lima Gonzalez, Patrícia Locosque Ramos, Marcia Regina von Zeska Kress, Eliana Guedes Stehling,

The rapid dissemination of extended-spectrum β-lactamases (ESBLs)-producing Enterobacterales from different spheres worldwide over recent years has become a serious problem in both human and veterinary medicine. CTX-M-3-type ESBL has only been reported on few occasions, and in Brazil the bla<sub>CTX-M-3</sub> gene has been identified only once in clinical strains. In ... Read more >>

Vet Microbiol (Veterinary microbiology)
[2020, 251:108909]

Cited: 1 time

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Biological activities of the protein hydrolysate obtained from two fishes common in the fisheries bycatch.

Tavani Rocha Camargo, Patrícia Ramos, José M Monserrat, Carlos Prentice, Célio J C Fernandes, Willian F Zambuzzi, Wagner C Valenti,

Shrimp trawling is an important socio-economic activity; however, the bycatch can be problematic to the environment. Thus, the present study investigated potential uses of the bycatch to generate value-added products. The biological activity of the protein hydrolysates obtained from the two most abundant fish species (Micropogonias furnieri and Paralonchurus brasiliensis) ... Read more >>

Food Chem (Food chemistry)
[2021, 342:128361]

Cited: 0 times

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Mobilizing a Public Health Response: Supporting the Perinatal Needs of New Yorkers During the COVID-19 Pandemic.

Elizabeth Claudio, Julia Donahue, P Mimi Niles, Anna Pirsch, Patricia Ramos, Ilish Neely, Regina Conceiçaõ, Mary-Powel Thomas, Tayisha St Vil, Deborah Kaplan,

Matern Child Health J (Maternal and child health journal)
[2020, 24(9):1083-1088]

Cited: 0 times

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Genomic Surveillance of Yellow Fever Virus Epizootic in São Paulo, Brazil, 2016 - 2018.

Sarah C Hill, Renato de Souza, Julien Thézé, Ingra Claro, Renato S Aguiar, Leandro Abade, Fabiana C P Santos, Mariana S Cunha, Juliana S Nogueira, Flavia C S Salles, Iray M Rocco, Adriana Y Maeda, Fernanda G S Vasami, Louis du Plessis, Paola P Silveira, Jaqueline G de Jesus, Joshua Quick, Natália C C A Fernandes, Juliana M Guerra, Rodrigo A Réssio, Marta Giovanetti, Luiz C J Alcantara, Cinthya S Cirqueira, Josué Díaz-Delgado, Fernando L L Macedo, Maria do Carmo S T Timenetsky, Regiane de Paula, Roberta Spinola, Juliana Telles de Deus, Luís F Mucci, Rosa Maria Tubaki, Regiane M T de Menezes, Patrícia L Ramos, Andre L de Abreu, Laura N Cruz, Nick Loman, Simon Dellicour, Oliver G Pybus, Ester C Sabino, Nuno R Faria,

São Paulo, a densely inhabited state in southeast Brazil that contains the fourth most populated city in the world, recently experienced its largest yellow fever virus (YFV) outbreak in decades. YFV does not normally circulate extensively in São Paulo, so most people were unvaccinated when the outbreak began. Surveillance in ... Read more >>

PLoS Pathog (PLoS pathogens)
[2020, 16(8):e1008699]

Cited: 6 times

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Zootechnical performance, biochemical response, and chromaticity in Pacific white shrimp (Litopenaeus vannamei) (Boone, 1931) after the inclusion of lyophilized açaí (Euterpe oleracea) in the diet

Shadai M Silva, Patricia B Ramos, Juan R Buitrago, Thamyres V N da Silva, Cleber S Simião, Grecica M Colombo, Marcos Schmitz, Marcelo B Tesser, Carlos Prentice, Wilson Wasielesky, José M Monserrat,

Functional foods have molecules that promote health benefits beyond their nutritional qualities. In this context, the zootechnical performance, color, and biochemical responses of Pacific white shrimp (Litopenaeus vannamei) fed with different levels of açaí (Euterpe oleracea), a fruit with unique antioxidant characteristics, were observed. Four diets with different levels of ... Read more >>

Aquac Int (Aquaculture international : journal of the European Aquaculture Society)
[2020, 28(4):1563-1577]

Cited: 0 times

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International high-risk clone of multidrug-resistant CTX-M-8-producing Escherichia coli C-ST410 infecting an elephant (Loxodonta africana) in a zoo.

João Pedro Rueda Furlan, Irys Hany Lima Gonzalez, Patrícia Locosque Ramos, Eliana Guedes Stehling,

J Glob Antimicrob Resist (Journal of global antimicrobial resistance)
[2020, 22:643-645]

Cited: 0 times

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Iodine levels in different regions of the human brain.

Edgar Pinto, Patrícia Ramos, Cristiana Vital, Agostinho Santos, Agostinho Almeida,

<h4>Background</h4>Iodine is a key component of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), which are crucial for proper growth and development of the human body. In particular, a great body of literature has been published on the link between thyroid hormones and brain development and functioning. However, there is ... Read more >>

J Trace Elem Med Biol (Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS))
[2020, 62:126579]

Cited: 0 times

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Cytomegalovirus Reactivation in Patients with Sepsis in an Intensive Care Unit in Portugal.

Paulo Paixão, Patricia Ramos, Cátia Piedade, André Casado, Maria Chasqueira,

<h4>Introduction</h4>In the last few years, cytomegalovirus reactivation has been considered an aggravating factor for septic patients in Intensive Care units. The main objectives of this study were to determine cytomegalovirus reactivation in patients with a diagnosis of sepsis admitted to an intensive care unit, and whether this reactivation was related ... Read more >>

Acta Med Port (Acta medica portuguesa)
[2020, 33(9):576-582]

Cited: 0 times

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Unveiling the bioactivity of Allium triquetrum L. lipophilic fractions: chemical characterization and in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus.

Samia Rabah, Kahina Kouachi, Patrícia A B Ramos, Ana Peixoto Gomes, Adelaide Almeida, Hayate Haddadi-Guemghar, Khodir Madani, Armando J D Silvestre, Sónia A O Santos,

The lipophilic composition of Allium triquetrum L. bulbs, flowers and leaves was studied for the first time by GC-MS. Sixty compounds were firstly identified in A. triquetrum L. Fatty acids represented the major lipophilic family among the studied extracts, with (9Z,12Z,15Z)-octadeca-9,12,15-trienoic and (9Z,12Z)-octadeca-9,12-dienoic acids being the major constituents of this ... Read more >>

Food Funct (Food & function)
[2020, 11(6):5257-5265]

Cited: 1 time

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Comparative analysis of multidrug resistance plasmids and genetic background of CTX-M-producing Escherichia coli recovered from captive wild animals.

João Pedro Rueda Furlan, Ralf Lopes, Irys Hany Lima Gonzalez, Patrícia Locosque Ramos, Eliana Guedes Stehling,

Multiple interlinked factors are associated with the global resistome, whereas multidrug-resistant (MDR) pathogens have been related to increased mortality rates in humans and animals. CTX-M-type is the most prevalent extended-spectrum β-lactamase (ESBL) among Enterobacteriaceae, which raises concern worldwide. Zoological gardens have a high density of animals that live very close ... Read more >>

Appl Microbiol Biotechnol (Applied microbiology and biotechnology)
[2020, 104(15):6707-6717]

Cited: 1 time

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Modulation of nodularin toxicity in shrimp Litopenaeus vannamei (BOONE, 1931) fed with dietary açai (Euterpe oleracea) inclusion.

Marcos Josué Schmitz, Grecica Mariana Colombo, Cleber Dos Santos Simião, Chaelen Rodrigues Ortiz, Luíza Dy Fonseca Costa, Thamyres Vanessa Nascimento da Silva, Patrícia Baptista Ramos, João Sarkis Yunes, Wilson Wasielesky, Marcelo Borges Tesser, José María Monserrat,

This study evaluated the effect of dietary inclusion of lyophilized açaí Euterpe oleracea (LEO) on redox status of shrimp Litopenaeus vannamei (initial weight 1.5 ± 0.39 g) upon exposure to cyanotoxin nodularin (NOD) in bioflocs system. Three hundred juvenile shrimps were randomly divided into two groups and fed twice a day with two ... Read more >>

Fish Shellfish Immunol (Fish & shellfish immunology)
[2020, 103:464-471]

Cited: 0 times

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New record of preclinical diagnosis of American visceral leishmaniasis in Amazonian Brazil encourages optimizing disease control.

Luciana Lima, Thiago Vasconcelos-Dos-Santos, Marliane Campos, Patrícia Karla Ramos, Claudia Gomes, Marcia Laurenti, Vania da Matta, Carlos Corbett, Fernando Silveira,

The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infection in Amazonian Brazil has recently been reviewed based on the combined use of the delayed-type hypersensitivity (DTH) and indirect fluorescence antibody test (IFAT-IgG/IgM), both with homologous L. (L.) infantum chagasi-antigens, and associated with the clinical evaluation of infected individuals. This diagnostic ... Read more >>

Parasite Epidemiol Control (Parasite epidemiology and control)
[2020, 10:e00154]

Cited: 2 times

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