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Author Pasquale Comberiati

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Reply to Russo et al.

Daniel Munblit, Nikita A Nekliudov, Polina Bugaeva, Oleg Blyuss, Peter Timashev, John O Warner, Pasquale Comberiati, Christian Apfelbacher, Mikhail E Politov, Andrey Yavorovskiy, Sergey Avdeev, Valentina A Kapustina, Victor Fomin, Andrey A Svistunov, Denis Butnaru, Petr Glybochko,

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Current transition management of adolescents and young adults with allergy and asthma: a European survey.

Ekaterina Khaleva, Marta Vazquez-Ortiz, Pasquale Comberiati, Audrey DunnGalvin, Helena Pite, Katharina Blumchen, Teresa Garriga-Baraut, Valerie Hox, Alexandra F Santos, Claudia Gore, Rebecca C Knibb, Cherry Alviani, Charlotte G Mortz, Elizabeth Angier, Bettina Duca, Britt Jensen, Silvia Sanchez-Garcia, M Hazel Gowland, Frans Timmermans, Oliver Pfaar, Graham Roberts,

Background:Transition from parent-delivered to self-management is a vulnerable time for adolescents and young adults (AYA) with allergy and asthma. There is currently no European guideline available for healthcare professionals (HCPs) on transition of these patients and local/national protocols are also mostly lacking. Methods:European HCPs working with AYA with allergy and ... Read more >>

Clin Transl Allergy (Clinical and translational allergy)
[2020, 10:40]

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StopCOVID cohort: An observational study of 3,480 patients admitted to the Sechenov University hospital network in Moscow city for suspected COVID-19 infection.

Daniel Munblit, Nikita A Nekliudov, Polina Bugaeva, Oleg Blyuss, Maria Kislova, Ekaterina Listovskaya, Aysylu Gamirova, Anastasia Shikhaleva, Vladimir Belyaev, Petr Timashev, John O Warner, Pasquale Comberiati, Christian Apfelbacher, Evgenii Bezrukov, Mikhail E Politov, Andrey Yavorovskiy, Ekaterina Bulanova, Natalya Tsareva, Sergey Avdeev, Valentina A Kapustina, Yuri I Pigolkin, Emmanuelle A Dankwa, Christiana Kartsonaki, Mark G Pritchard, Fomin Victor, Andrey A Svistunov, Denis Butnaru, Petr Glybochko,

BACKGROUND:The epidemiology, clinical course, and outcomes of COVID-19 patients in the Russian population are unknown. Information on the differences between laboratory-confirmed and clinically-diagnosed COVID-19 in real-life settings is lacking. METHODS:We extracted data from the medical records of adult patients who were consecutively admitted for suspected COVID-19 infection in Moscow, between ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Excessive Media Consumption About COVID-19 is Associated With Increased State Anxiety: Outcomes of a Large Online Survey in Russia.

Nikita A Nekliudov, Oleg Blyuss, Ka Yan Cheung, Loukia Petrou, Jon Genuneit, Nikita Sushentsev, Anna Levadnaya, Pasquale Comberiati, John O Warner, Gareth Tudor-Williams, Martin Teufel, Matthew Greenhawt, Audrey DunnGalvin, Daniel Munblit,

BACKGROUND:The COVID-19 pandemic has potentially had a negative impact on the mental health and well-being of individuals and families. Anxiety levels and risk factors within particular populations are poorly described. OBJECTIVE:This study aims to evaluate confidence, understanding, trust, concerns, and levels of anxiety during the COVID-19 pandemic in the general ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2020, 22(9):e20955]

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Dietary Interventions and Nutritional Factors in the Prevention of Pediatric Asthma.

Irene Trambusti, Giulia Nuzzi, Giorgio Costagliola, Elvira Verduci, Enza D'Auria, Diego G Peroni, Pasquale Comberiati,

Asthma is the most frequent chronic disease in children, and its pathogenesis involves genetic, epigenetic, and environmental factors. The rapid rise in the prevalence of asthma registered over the last few decades has stressed the need to identify the environmental and modifiable factors associated with the development of the disease. ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:480]

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The effectiveness of interventions to improve self-management for adolescents and young adults with allergic conditions: A systematic review.

Rebecca C Knibb, Cherry Alviani, Teresa Garriga-Baraut, Charlotte G Mortz, Marta Vazquez-Ortiz, Elizabeth Angier, Katerina Blumchen, Pasquale Comberiati, Bettina Duca, Audrey DunnGalvin, Claudia Gore, Valerie Hox, Britt Jensen, Helena Pite, Alexandra F Santos, Silvia Sanchez-Garcia, M Hazel Gowland, Frans Timmermans, Graham Roberts,

BACKGROUND:This systematic review aimed to review the literature on interventions for improving self-management and well-being in adolescents and young adults (11-25 years) with asthma and allergic conditions. METHODS:A systematic literature search was undertaken across eight databases. References were checked by two reviewers for inclusion. Study data were extracted, and their quality ... Read more >>

Allergy (Allergy)
[2020, 75(8):1881-1898]

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Understanding the challenges faced by adolescents and young adults with allergic conditions: A systematic review.

Marta Vazquez-Ortiz, Elizabeth Angier, Katharina Blumchen, Pasquale Comberiati, Bettina Duca, Audrey DunnGalvin, Claudia Gore, Valérie Hox, Britt Jensen, Helena Pite, Alexandra F Santos, Silvia Sanchez, Cherry Alviani, Teresa Garriga-Baraut, Rebecca Knibb, Charlotte G Mortz, M Hazel Gowland, Frans Timmermans, Graham Roberts,

BACKGROUND:Adolescence represents a vulnerable time for individuals with asthma and allergic conditions. They suffer an unexpected degree of morbidity. This systematic review aimed to understand the challenges faced by adolescents and young adults with these conditions. METHODS:A systematic literature search was undertaken across eight databases. References were checked by two ... Read more >>

Allergy (Allergy)
[2020, 75(8):1850-1880]

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EAACI Guidelines on the effective transition of adolescents and young adults with allergy and asthma.

Graham Roberts, Marta Vazquez-Ortiz, Rebecca Knibb, Ekaterina Khaleva, Cherry Alviani, Elizabeth Angier, Katharina Blumchen, Pasquale Comberiati, Bettina Duca, Audrey DunnGalvin, Teresa Garriga-Baraut, Claudia Gore, M Hazel Gowland, Valérie Hox, Britt Jensen, Charlotte G Mortz, Oliver Pfaar, Helena Pite, Alexandra F Santos, Silvia Sanchez-Garcia, Frans Timmermans,

Adolescent and young adult (AYA) patients need additional support, while they experience the challenges associated with their age. They need specific training to learn the knowledge and skills required to confidently self-manage their allergies and/or asthma. Transitional care is a complex process, which should address the psychological, medical, educational and ... Read more >>

Allergy (Allergy)
[2020, 75(11):2734-2752]

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Fractional exhaled nitric oxide response to oral corticosteroids in children with mild-to-moderate asthma: Influence of race.

Pasquale Comberiati, Diego Peroni, Jonathan Malka-Rais, Riccardo Morganti, Joseph D Spahn,

BACKGROUND:Fractional exhaled nitric oxide (FeNO) is a noninvasive biomarker of type 2 asthma that can predict response to inhaled corticosteroid therapy. Little is known regarding the magnitude of FeNO reduction after an oral corticosteroid (OCS) course, and less is known whether there are differential responses based on race in children ... Read more >>

Ann Allergy Asthma Immunol (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology)
[2020, 125(4):440-446.e1]

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Potential effects of E-cigarettes and vaping in pediatric asthma.

Maria Di Cicco, Margherita Sepich, Vincenzo Ragazzo, Diego G Peroni, Pasquale Comberiati,

INTRODUCTION:Asthma is the most common chronic disease in childhood and exposure to tobacco smoke has been long recognized as a risk factor for its onset as well as for exacerbations and poor disease control. Since the early 2000s, electronic cigarettes have been marketed worldwide as a non-harmful electronic alternative to ... Read more >>

Minerva Pediatr (Minerva pediatrica)
[2020, :]

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Go With Your Gut: The Shaping of T-Cell Response by Gut Microbiota in Allergic Asthma.

Alessandro Di Gangi, Maria Elisa Di Cicco, Pasquale Comberiati, Diego G Peroni,

Novel methods in immunological research and microbiome evaluation have dramatically changed several paradigms associated with the pathogenesis of allergic asthma (AAS). Ovalbumin and house dust mite-induced AAS in germ-free or specific pathogen-free mice are the two leading experimental platforms that significantly contribute to elucidate the relationship between AAS and gut ... Read more >>

Front Immunol (Frontiers in immunology)
[2020, 11:1485]

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Hyaluronic acid for the treatment of airway diseases in children: Little evidence for few indications.

Maria Di Cicco, Diego Peroni, Margherita Sepich, Maria Giulia Tozzi, Pasquale Comberiati, Renato Cutrera,

BACKGROUND:Hyaluronic acid (HA) is major physiological component of the extracellular matrix, which, in its high molecular weight form (HMW-HA) has anti-inflammatory properties. The diffusion of many different medical devices for inhalation therapy containing HA has led to an increase in their prescription, also in children. Here, we systematically review the ... Read more >>

Pediatr Pulmonol (Pediatric pulmonology)
[2020, 55(8):2156-2169]

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Vitamin D supplementation in pregnancy does not prevent school-age asthma.

Pasquale Comberiati, Diego G Peroni,

Allergy (Allergy)
[2020, 75(8):2143-2144]

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Current Transition Management of Adolescents and Young Adults with Allergy and Asthma: A European Survey.

Ekaterina Khaleva, Marta Vazquez-Ortiz, Pasquale Comberiati, Audrey DunnGalvin, Helena Pite, Katharina Blumchen, Teresa Garriga-Baraut, Valerie Hox, Alexandra Santos, Claudia Gore, Rebecca Knibb, Cherry Alviani, Charlotte Mortz, Elizabeth Angier, Bettina Duca, Britt Jensen, Silvia Sanchez-Garcia, Hazel Gowland, Frans Timmermans, Oliver Pfaar, Graham Roberts,

Abstract Background: Transition from parent-delivered to self-management is a vulnerable time for adolescents and young adults (AYA) with allergy and asthma. There is currently no European guideline available for healthcare professionals (HCPs) on transition of these patients and local/national protocols are also mostly lacking. Methods: European HCPs working with AYA ... Read more >>

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Topical corticosteroids for pediatric atopic dermatitis: Thoughtful tips for practice.

Andrea Chiricozzi, Pasquale Comberiati, Enza D'Auria, GianVincenzo Zuccotti, Diego G Peroni,

Atopic dermatitis (AD) is one of the most common chronic inflammatory skin disease, affecting up to 25% of children. Topical corticosteroids (TCS) are currently used as first-line antiinflammatory treatment for AD, due to their overall therapeutic efficacy, and the availability of different potency classes and a wide array of formulations. ... Read more >>

Pharmacol Res (Pharmacological research)
[2020, 158:104878]

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Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020.

Silvia Garazzino, Carlotta Montagnani, Daniele Donà, Antonella Meini, Enrico Felici, Gianluca Vergine, Stefania Bernardi, Roberta Giacchero, Andrea Lo Vecchio, Paola Marchisio, Giangiacomo Nicolini, Luca Pierantoni, Ivana Rabbone, Giuseppe Banderali, Marco Denina, Elisabetta Venturini, Andrzej Krzysztofiak, Raffaele Badolato, Sonia Bianchini, Luisa Galli, Alberto Villani, Guido Castelli-Gattinara, , ,

Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day-17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever ... Read more >>

Euro Surveill (Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin)
[2020, 25(18):]

Cited: 13 times

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Microbiome Composition and Its Impact on the Development of Allergic Diseases.

Diego G Peroni, Giulia Nuzzi, Irene Trambusti, Maria Elisa Di Cicco, Pasquale Comberiati,

Allergic diseases, such as food allergy (FA), atopic dermatitis (AD), and asthma, are heterogeneous inflammatory immune-mediated disorders that currently constitute a public health issue in many developed countries worldwide. The significant increase in the prevalence of allergic diseases reported over the last few years has closely paralleled substantial environmental changes ... Read more >>

Front Immunol (Frontiers in immunology)
[2020, 11:700]

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The role of atopy in asthma development and persistence.

Maria Di Cicco, Sofia D'Elios, Diego G Peroni, Pasquale Comberiati,

PURPOSE OF REVIEW:Asthma is the most common chronic disease in pediatric age. Childhood-onset asthma, as opposed to adult-onset asthma, is typically characterized by a personal and often a family history of atopy and related markers of type 2-mediated inflammation. However, the interplay between atopy and asthma development is more complex ... Read more >>

Curr Opin Allergy Clin Immunol (Current opinion in allergy and clinical immunology)
[2020, 20(2):131-137]

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Lung mechanical properties distinguish children with asthma with normal and diminished lung function.

Pasquale Comberiati, Joseph D Spahn, Keith Paull, Anna Faino, Reuben Cherniack, Ronina A Covar,

BACKGROUND:Children with asthma, even those with severe persistent disease, can have forced expiratory volume in 1 second (FEV1 ) values ≥100% of predicted, while others have diminished FEV1 . OBJECTIVE:We sought to characterize the lung mechanical properties underlying these two asthma phenotypes and the mechanisms explaining the paradox of severe asthmatic ... Read more >>

Clin Exp Allergy (Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology)
[2020, 50(4):453-462]

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The need for clean air: The way air pollution and climate change affect allergic rhinitis and asthma.

Ibon Eguiluz-Gracia, Alexander G Mathioudakis, Sabine Bartel, Susanne J H Vijverberg, Elaine Fuertes, Pasquale Comberiati, Yutong Samuel Cai, Peter Valentin Tomazic, Zuzana Diamant, Jørgen Vestbo, Carmen Galan, Barbara Hoffmann,

Air pollution and climate change have a significant impact on human health and well-being and contribute to the onset and aggravation of allergic rhinitis and asthma among other chronic respiratory diseases. In Westernized countries, households have experienced a process of increasing insulation and individuals tend to spend most of their ... Read more >>

Allergy (Allergy)
[2020, 75(9):2170-2184]

Cited: 3 times

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Current transition management of adolescents and young adults with allergy and asthma: a European survey

Ekaterina Khaleva, Marta Vazquez-Ortiz, Pasquale Comberiati, Audrey DunnGalvin, Helena Pite, Katharina Blumchen, Teresa Garriga-Baraut, Valerie Hox, Alexandra F. Santos, Claudia Gore, Rebecca C. Knibb, Cherry Alviani, Charlotte G. Mortz, Elizabeth Angier, Bettina Duca, Britt Jensen, Silvia Sanchez-Garcia, M. Hazel Gowland, Frans Timmermans, Oliver Pfaar, Graham Roberts,

Background Transition from parent-delivered to self-management is a vulnerable time for adolescents and young adults (AYA) with allergy and asthma. There is currently no European guideline available for healthcare professionals (HCPs) on transition of these patients and local/national protocols are also mostly lacking. Methods European HCPs working with AYA with ... Read more >>

Clin Transl Allergy (Clinical and translational allergy)
[2020, 10:]

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Practical Approach to Children Presenting with Eosinophila and Hypereosinophilia.

Giorgio Costagliola, Serena Di Marco, Pasquale Comberiati, Sofia D'Elios, Nino Petashvili, Maria Elisa Di Cicco, Diego Peroni,

Eosinophilia is not a rare finding in clinical practice, and often poses problems in terms of etiologic research and differential diagnosis. Peripheral eosinophilia is defined by a blood eosinophil count > 500 cells/μL. It is classified into mild (500-1500 cells/μl), moderate (1500-5000 cells/μl) and severe for an eosinophil count > ... Read more >>

Curr Pediatr Rev (Current pediatric reviews)
[2020, 16(2):81-88]

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Dietary Interventions and Nutritional Factors in the Prevention of Pediatric Asthma

Irene Trambusti, Giulia Nuzzi, Giorgio Costagliola, Elvira Verduci, Enza D'Auria, Diego G. Peroni, Pasquale Comberiati,

Asthma is the most frequent chronic disease in children, and its pathogenesis involves genetic, epigenetic, and environmental factors. The rapid rise in the prevalence of asthma registered over the last few decades has stressed the need to identify the environmental and modifiable factors associated with the development of the disease. ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:]

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Wet Cough and Nasal Symptoms in Children: Can We Do Better?

Fernando M de Benedictis, Ines Carloni, Pasquale Comberiati, Michael D Shields, Andrew Bush, Anne B Chang,

The causes of chronic cough in children are mainly dependent on the setting and age of the child. Protracted bacterial bronchitis is a frequent cause of morbidity in childhood, and antibiotic treatment is beneficial. Prompt recognition and early treatment is important both to prevent inappropriate use of asthma medications and ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:459]

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Anaphylaxis in adolescents.

Pasquale Comberiati, Joseph Spahn, Diego G Peroni,

PURPOSE OF REVIEW:The frequency of hospitalization for anaphylaxis has increased over the last 20 years across Europe, Australia, and North America, particularly, for food and medication triggers. Adolescents show the highest risk for morbidity and fatality from food-induced anaphylaxis, yet there is little high-quality evidence addressing the reasons for this ... Read more >>

Curr Opin Allergy Clin Immunol (Current opinion in allergy and clinical immunology)
[2019, 19(5):425-431]

Cited: 1 time

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