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Role of α- and β-adrenergic signaling in phenotypic targeting: significance in benign and malignant urologic disease.

M Archer, N Dogra, Z Dovey, T Ganta, H-S Jang, J A Khusid, A Lantz, M Mihalopoulos, J A Stockert, A Zahalka, L Björnebo, S Gaglani, M R Noh, S A Kaplan, R Mehrazin, K K Badani, P Wiklund, K Tsao, D J Lundon, N Mohamed, F Lucien, B Padanilam, M Gupta, A K Tewari, N Kyprianou,

The urinary tract is highly innervated by autonomic nerves which are essential in urinary tract development, the production of growth factors, and the control of homeostasis. These neural signals may become dysregulated in several genitourinary (GU) disease states, both benign and malignant. Accordingly, the autonomic nervous system is a therapeutic ... Read more >>

Cell Commun Signal (Cell communication and signaling : CCS)
[2021, 19(1):78]

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Upstaging and Survival Outcomes for Non-Muscle Invasive Bladder Cancer After Radical Cystectomy: Results from the International Robotic Cystectomy Consortium.

Umar Iqbal, Ahmed S Elsayed, Zhe Jing, Michael Stoeckle, Carl Wijburg, Peter Wiklund, Abolfazl Hosseini, Prokar Dasgupta, Muhammad Shamim Khan, Ashok Hemal, Eric H Kim, Andrew A Wagner, Franco Gaboardi, Koon Ho Rha, Thomas Maatman, Derya Balbay, Qiang Li, Ahmed Hussein, Khurshid A Guru,

<h4>Introduction</h4>We sought to describe the incidence, risk factors, and survival outcomes associated with pathological upstaging from non-muscle invasive bladder cancer (NMIBC) to muscle invasive bladder cancer (MIBC) after robot-assisted radical cystectomy (RARC).<h4>Methods</h4>We reviewed the International Robotic Cystectomy Consortium database between 2004 and 2020. Upstaging was defined as ≥pT2 or pN+ ... Read more >>

J Endourol (Journal of endourology)
[2021, :]

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Interactive effects of aging and aerobic capacity on energy metabolism-related metabolites of serum, skeletal muscle, and white adipose tissue.

Haihui Zhuang, Sira Karvinen, Timo Törmäkangas, Xiaobo Zhang, Xiaowei Ojanen, Vidya Velagapudi, Markku Alen, Steven L Britton, Lauren G Koch, Heikki Kainulainen, Sulin Cheng, Petri Wiklund,

Aerobic capacity is a strong predictor of longevity. With aging, aerobic capacity decreases concomitantly with changes in whole body metabolism leading to increased disease risk. To address the role of aerobic capacity, aging, and their interaction on metabolism, we utilized rat models selectively bred for low and high intrinsic aerobic ... Read more >>

Geroscience (GeroScience)
[2021, :]

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Clinical characteristics and oncological outcomes in negative multiparametric MRI patients undergoing robot-assisted radical prostatectomy.

Vinayak G Wagaskar, Parita Ratnani, Micah Levy, Kate Moody, Mariely Garcia, Adriana M Pedraza, Sneha Parekh, Krunal Pandav, Bhavya Shukla, Stanislaw Sobotka, Kenneth Haines, Peter Wiklund, Ash Tewari,

<h4>Background</h4>Efforts are ongoing to try and find ways to reduce the number of unnecessary prostate biopsies without missing clinically significant prostate cancers (csPCa). The utility of multiparametric magnetic resonance imaging (mpMRI) in detecting prostate cancer (PCa) shows promise to be used as triage test for systematic prostate biopsy. Our aim ... Read more >>

Prostate (The Prostate)
[2021, 81(11):772-777]

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Impact of the Implementation of the EAU Guidelines Recommendation on Reporting and Grading of Complications in Patients Undergoing Robot-assisted Radical Cystectomy: A Systematic Review.

Paolo Dell'Oglio, Iulia Andras, David Ortega, Antonio Galfano, Walter Artibani, Riccardo Autorino, Elio Mazzone, Nicolae Crisan, Aldo Massimo Bocciardi, Rafael Sanchez-Salas, Inderbir Gill, Peter Wiklund, Mihir Desai, Dionysios Mitropoulos, Alexandre Mottrie, Giovanni E Cacciamani,

In 2012, the European Association of Urology (EAU) Ad Hoc Panel proposed a standardised methodology on reporting and grading complications after urological surgical procedures. The aim of the current study was to assess the impact of this implementation on complications reporting for patients undergoing robot-assisted radical cystectomy (RARC). A systematic ... Read more >>

Eur Urol (European urology)
[2021, 80(2):129-133]

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Robotic assisted radical cystectomy versus open radical cystectomy: a review of what we do and don't know.

Zeynep G Gul, Andrew B Katims, Jared S Winoker, Peter Wiklund, Nikhil Waingankar, Reza Mehrazin,

Radical cystectomy (RC) is the gold standard treatment for muscle-invasive and high-risk, noninvasive bladder cancer. Since 2003, robot-assisted radical cystectomy (RARC) has been gaining popularity. Metanalyses show that the primary advantage of RARC is less blood loss and the primary advantage of open radical cystectomy (ORC) is shorter operative times. ... Read more >>

Transl Androl Urol (Translational andrology and urology)
[2021, 10(5):2209-2215]

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Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing.

Li Wang, John P Sfakianos, Kristin G Beaumont, Guray Akturk, Amir Horowitz, Robert P Sebra, Adam M Farkas, Sacha Gnjatic, Austin Hake, Sudeh Izadmehr, Peter Wiklund, William K Oh, Peter M Szabo, Megan Wind-Rotolo, Keziban Unsal-Kacmaz, Xin Yao, Eric Schadt, Padmanee Sharma, Nina Bhardwaj, Jun Zhu, Matthew D Galsky,

<h4>Purpose</h4>To define dominant molecular and cellular features associated with PD-1/PD-L1 blockade resistance in metastatic urothelial cancer.<h4>Experimental design</h4>We pursued an unbiased approach using bulk RNA sequencing data from two clinical trials to discover (IMvigor 210) and validate (CheckMate 275) pretreatment molecular features associated with resistance to PD-1/PD-L1 blockade in metastatic urothelial ... Read more >>

Clin Cancer Res (Clinical cancer research : an official journal of the American Association for Cancer Research)
[2021, :]

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Urinary continence recovery and oncological outcomes after surgery for prostate cancer analysed by risk category: results from the LAParoscopic prostatectomy robot and open trial.

Anna Hagman, Anna Lantz, Stefan Carlsson, Jonas Höijer, Johan Stranne, S I Tyritzis, Eva Haglind, Anders Bjartell, Jonas Hugosson, Olof Akre, Gunnar Steineck, Peter Wiklund,

<h4>Purpose</h4>To evaluate urinary continence (UC) recovery and oncological outcomes in different risk-groups after robot-assisted radical prostatectomy (RALP) and open retropubic radical prostatectomy (RRP).<h4>Patients and methods</h4>We analysed 2650 men with prostate cancer from seven open (n = 805) and seven robotic (n = 1845) Swedish centres between 2008 and 2011 in a prospective non-randomised trial, ... Read more >>

World J Urol (World journal of urology)
[2021, :]

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Management of patients who opt for radical prostatectomy during the coronavirus disease 2019 (COVID-19) pandemic: an international accelerated consensus statement.

Zafer Tandogdu, Justin Collins, Greg Shaw, Jennifer Rohn, Bela Koves, Ashwin Sachdeva, Ahmed Ghazi, Alexander Haese, Alex Mottrie, Anup Kumar, Ananthakrishnan Sivaraman, Ashutosh Tewari, Benjamin Challacombe, Bernardo Rocco, Camilo Giedelman, Christian Wagner, Craig G Rogers, Declan G Murphy, Dmitry Pushkar, Gabriel Ogaya-Pinies, James Porter, Kulthe Ramesh Seetharam, Markus Graefen, Marcelo A Orvieto, Marcio Covas Moschovas, Oscar Schatloff, Peter Wiklund, Rafael Coelho, Rair Valero, Theo M de Reijke, Thomas Ahlering, Travis Rogers, Henk G van der Poel, Vipul Patel, Walter Artibani, Florian Wagenlehner, Kris Maes, Koon H Rha, Senthil Nathan, Truls Erik Bjerklund Johansen, Peter Hawkey, John Kelly,

<h4>Objective</h4>Coronavirus disease-19 (COVID-19) pandemic caused delays in definitive treatment of patients with prostate cancer. Beyond the immediate delay a backlog for future patients is expected. The objective of this work is to develop guidance on criteria for prioritisation of surgery and reconfiguring management pathways for patients with non-metastatic prostate cancer ... Read more >>

BJU Int (BJU international)
[2021, 127(6):729-741]

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A 4K score/MRI-based nomogram for predicting prostate cancer, clinically significant prostate cancer, and unfavorable prostate cancer.

Vinayak G Wagaskar, Stanislaw Sobotka, Parita Ratnani, James Young, Anna Lantz, Sneha Parekh, Ugo Giovanni Falagario, Li Li, Sara Lewis, Kenneth Haines, Sanoj Punnen, Peter Wiklund, Ash Tewari,

<h4>Background</h4>The detection of prostate cancer requires histological confirmation in biopsy core. Currently, number of unnecessary prostate biopsies are being performed in the United States. This is due to the absence of appropriate biopsy decision-making protocol.<h4>Aim</h4>To develop and validate a 4K score/multiparametric magnetic resonance imaging (mpMRI)-based nomogram to predict prostate cancer ... Read more >>

Cancer Rep (Hoboken) (Cancer reports (Hoboken, N.J.))
[2021, :e1357]

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Implementation of a nonopioid protocol following robot-assisted radical cystectomy with intracorporeal urinary diversion.

John L Pfail, Evan B Garden, Zeynep Gul, Andrew B Katims, Shoshana J Rosenzweig, Shirin Razdan, Olamide Omidele, Sarah Nathaniel, Katherine Loftus, Alan Sim, Reza Mehrazin, Peter N Wiklund, John P Sfakianos,

<h4>Purpose</h4>The implementation of robot-assisted radical cystectomy (RARC) with intracorporeal urinary diversion (ICUD) for management of patients with muscle-invasive or high-risk noninvasive bladder cancer has increased in utilization over the last decade. Here, we seek to describe institutional opioid prescription and utilization patterns following implementation of a nonopioid (NOP) perioperative pain ... Read more >>

Urol Oncol (Urologic oncology)
[2021, 39(7):436.e9-436.e16]

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Definition of a Structured Training Curriculum for Robot-assisted Radical Cystectomy with Intracorporeal Ileal Conduit in Male Patients: A Delphi Consensus Study Led by the ERUS Educational Board.

Paolo Dell'Oglio, Filippo Turri, Alessandro Larcher, Frederiek D'Hondt, Rafael Sanchez-Salas, Bernard Bochner, Joan Palou, Robin Weston, Abolfazl Hosseini, Abdullah E Canda, Jørgen Bjerggaard, Giovanni Cacciamani, Kasper Ørding Olsen, Inderbir Gill, Thierry Piechaud, Walter Artibani, Pim J van Leeuwen, Arnulf Stenzl, John Kelly, Prokar Dasgupta, Carl Wijburg, Justin W Collins, Mihir Desai, Henk G van der Poel, Francesco Montorsi, Peter Wiklund, Alexandre Mottrie, ,

Robot-assisted radical cystectomy (RARC) continues to expand, and several surgeons start training for this complex procedure. This calls for the development of a structured training program, with the aim to improve patient safety during RARC learning curve. A modified Delphi consensus process was started to develop the curriculum structure. An ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Objective assessment of intraoperative skills for robot-assisted radical prostatectomy (RARP): results from the ERUS Scientific and Educational Working Groups Metrics Initiative.

Alexandre Mottrie, Elio Mazzone, Peter Wiklund, Markus Graefen, Justin W Collins, Ruben De Groote, Paolo Dell'Oglio, Stefano Puliatti, Anthony G Gallagher,

<h4>Objective</h4>To develop and seek consensus from procedure experts on the metrics that best characterise a reference robot-assisted radical prostatectomy (RARP) and determine if the metrics distinguished between the objectively assessed RARP performance of experienced and novice urologists, as identifying objective performance metrics for surgical training in robotic surgery is imperative ... Read more >>

BJU Int (BJU international)
[2021, 128(1):103-111]

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Predicting morbidity and mortality after radical cystectomy using risk calculators: A comprehensive review of the literature.

Shirin Razdan, Michaela Sljivich, John Pfail, Peter K Wiklund, John P Sfakianos, Nikhil Waingankar,

<h4>Introduction</h4>Radical cystectomy (RC) with urinary diversion is associated with significant perioperative morbidity and mortality, varying between 30% and 70% and between 0.3% and 10.6%, respectively. Risk calculators have been extensively studied in the general surgery literature to predict 30- and 90-day postoperative morbidity and mortality but have not been widely ... Read more >>

Urol Oncol (Urologic oncology)
[2021, 39(2):109-120]

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Corrigendum re "Best Practices in Robotic-assisted Repair of Vesicovaginal Fistula: A Consensus Report from the European Association of Urology Robotic Urology Section Scientific Working Group for Reconstructive Urology" [Eur Urol 2020;78:432-42].

Marco Randazzo, Linda Lengauer, Charles-Henry Rochat, Achilles Ploumidis, Darko Kröpfl, Jens Rassweiler, Nicolo Maria Buffi, Peter Wiklund, Alexandre Mottrie, Hubert John,

Eur Urol (European urology)
[2021, 79(2):e63]

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Morbidity and mortality after robot-assisted radical cystectomy with intracorporeal urinary diversion in octogenarians: results from the European Association of Urology Robotic Urology Section Scientific Working Group.

Ashkan Mortezavi, Alessio Crippa, Sebastian Edeling, Sasa Pokupic, Paolo Dell'Oglio, Francesco Montorsi, Frederiek D'Hondt, Alexandre Mottrie, Karel Decaestecker, Carl J Wijburg, Justin Collins, John D Kelly, Wei Shen Tan, Ashwin Sridhar, Hubert John, Abdullah Erdem Canda, Christian Schwentner, Erik Peder Rönmark, Peter Wiklund, Abolfazl Hosseini,

<h4>Objectives</h4>To evaluate the postoperative complication and mortality rate following laparoscopic radical cystectomy (RARC) with intracorporeal urinary diversion (ICUD) in octogenarians.<h4>Patients and methods</h4>We conducted a retrospective analysis comparing postoperative complication and mortality rates depending on age in a consecutive series of 1890 patients who underwent RARC with ICUD for bladder cancer ... Read more >>

BJU Int (BJU international)
[2021, 127(5):585-595]

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Hood Technique for Robotic Radical Prostatectomy-Preserving Periurethral Anatomical Structures in the Space of Retzius and Sparing the Pouch of Douglas, Enabling Early Return of Continence Without Compromising Surgical Margin Rates.

Vinayak G Wagaskar, Ankur Mittal, Stanislaw Sobotka, Parita Ratnani, Anna Lantz, Ugo Giovanni Falagario, Alberto Martini, Zach Dovey, Patrick-Julien Treacy, Prachee Pathak, Suit Nair, Berryhill Roy, Dimple Chakravarty, Sara Lewis, Kenneth Haines, Peter Wiklund, Ash Tewari,

<h4>Background</h4>A common side effect following radical prostatectomy is urinary incontinence. Here, we describe a novel surgical technique to reduce postoperative urinary incontinence and facilitate early return of continence.<h4>Objective</h4>To describe the novel "hood technique" for robotic-assisted radical prostatectomy (RARP).<h4>Design, setting, and participants</h4>This is an institutional review board-approved prospective study of 300 ... Read more >>

Eur Urol (European urology)
[2021, 80(2):213-221]

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Surgeon heterogeneity significantly affects functional and oncological outcomes after radical prostatectomy in the Swedish LAPPRO trial.

Martin Nyberg, Daniel D Sjoberg, Sigrid V Carlsson, Ulrica Wilderäng, Stefan Carlsson, Johan Stranne, Peter Wiklund, Gunnar Steineck, Eva Haglind, Jonas Hugosson, Anders Bjartell,

<h4>Objectives</h4>To evaluate how surgeon heterogeneity - the variation in outcomes between individual surgeons - influences functional and oncological outcomes after robot-assisted laparoscopic prostatectomy (RALP) and retropubic radical prostatectomy (RRP), and to assess whether surgeon heterogeneity affects the comparison between RALP and RRP.<h4>Patients and methods</h4>Laparoscopic Prostatectomy Robot Open (LAPPRO) is a ... Read more >>

BJU Int (BJU international)
[2021, 127(3):361-368]

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Can anesthetics affect bladder cancer recurrence? Total intravenous versus volatile anesthesia in patients undergoing robot-assisted radical cystectomy: A single institution retrospective analysis.

John L Pfail, Andrew B Katims, Zeynep Gul, Shoshana J Rosenzweig, Shirin Razdan, Sarah Nathaniel, Alberto Martini, Reza Mehrazin, Peter N Wiklund, Katherine Loftus, Alan Sim, Samuel DeMaria, John P Sfakianos,

<h4>Background</h4>Radical cystectomy is standard of care and part of a multidisciplinary approach for long-term survival in patients with muscle-invasive bladder cancer (MIBC) or high-grade non-MIBC. Recent data have suggested that anesthetic technique can affect long-term survival and recurrence in patients undergoing cancer related surgery.<h4>Methods</h4>The records of all patients who underwent ... Read more >>

Urol Oncol (Urologic oncology)
[2021, 39(4):233.e1-233.e8]

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Myeloid cell-associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing

Li Wang, John Sfakianos, Kristin Beaumont, Guray Akturk, Amir Horowitz, Robert Sebra, Adam Farkas, Sacha Gnjatic, Austin Hake, Sudeh Izadmehr, Peter Wiklund, William Oh, Peter Szabo, Megan Wind-Rotolo, Kezi Unsal-Kacmaz, Xin Yao, Eric Schadt, Padmanee Sharma, Nina Bhardwaj, Jun Zhu, Matthew Galsky,

Adaptive immunity and tumor-promoting inflammation exist in delicate balance in individual tumor microenvironments; however, the role of this balance in defining sensitivity and resistance to PD-1/PD-L1 blockade therapy in urothelial cancer and other malignancies is poorly understood. We pursued an unbiased systems biology approach using bulk RNA sequencing data to ... Read more >>

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Northeastern Section of the AUA 72nd Annual Meeting Abstracts

Laura Donnelly, Jackie Tang, Fei Lian, Paul J. Higgins, Rohan Samarakoon, Karen Doersch, Kadija Abston, Hannah Kim, Xin Li, Jennifer Bjazevic, Anna-Lena Spierling, Kait F. Al, Hassan Razvi, Jeremy Burton, Jennifer Bjazevic, Kait F. Al, Jeremy P. Burton, Hassan Razvi, Gabriel Lachance, Karine Robitaille, Hélène Hovington, Alain Bergeron, Yves Fradet, Vincent Fradet, Connor Policastro, Michael Hughes, Francisco Martins, Jay Simhan, Nicolaas Lumen, Krishnan Venkatesan, Erick Alejandro Ramírez Pérez, Javier Angulo, Shubham Gupta, Paul Rusilko, Kirk Redger, Brian Flynn, Stephen Blakely, Dmitriy Nikolavsky, Kelly Pekala, Valentina Grajales, Hermoon Worku, Jordan Hay, Toby Zhu, Kody Armann, Chandler Hudson, Michelle Yu, Jathin Bandari, Benjamin Davies, Bruce Jacobs, Jessica Schardein, Matthew Beamer, Dmitriy Nikolavsky, Mauro Dispagna, Connor Policastro, Sergey Kravchick, Gregg Eure, Steven Gange, Andrew Hirsh, Hugh Reeves, Thomas Mueller, Peter Walter, Douglas Grier, Daniel Rukstalis, Sohrab Naushad Ali, Nicholas Paterson, Kristen McAlpine, Tinghua Zhang, Brian Blew, Neal Rowe, Charles Welliver, Lydia Feinstein, Julia Ward, Kevin Abbott, Ziya Kirkali, Erline Martinez-Miller, Brian Matlaga, Kevin McVary, Michelle Yu, Kelly R. Pekala, Hermoon Worku, Kody M. Armann, Chandler Hudson, Toby Zhu, Jordan M. Hay, Valentina Grajales, Jathin Bandari, Benjamin J. Davies, Bruce L. Jacobs, David Miller, Avinash Maganty, Oluwaseun Orikogobo, Kelly Pekala, Paul Rusilko, Alexandr Pinkhasov, Adam Cole, Scott Wiener, Mark Arthur, David Kozminski, Kim Williams, Paul Feustel, Christopher Stark, Lawrence Keatin, Gary Siskin, Allen Herr, Charles Welliver, Hermoon Worku, Kelly Pekala, Olutiwa Akomolede, Kody Armann, Anup Shah, Valentina Grajales, Oluwaseun Orikogbo, Devin Rogers, Michelle Yu, Jathin Bandari, Benjamin Davies, Bruce Jacobs, Zafardjan Dalimov, Nicole Alavi-Dunn, Julia S. Yu, Jordan S. Levine, K. Kent Chevli, Nicole Alavi-Dunn, Zafardjan Dalimov, Ali Houjaij, Jeffrey Villanueva, Valentina Grajales, Marc Colaco, Omar Ayyash, Rajeev Chaudhry, Francis Schneck, Glenn Cannon, Janelle Fox, Jin Kyu (Justin) Kim, Armando Lorenzo, Lucshman Raveendran, Michael Chua, Jessica Ming, Walid Farhat, Martin Koyle, Daniel Pelzman, Omar Ayyash, Marc Colaco, Glenn Cannon, Lucshman Raveendran, Joana Dos Santos, Martha Pokarowski, Edyta Marcon, Reza Vali, Afsaneh Amirabadi, Dean Elterman, Richard Foty, Armando Lorenzo, Martin Koyle, Jeffrey Villanueva, Brian Kocack, Marc Colaco, Benjamin Pifer, Francis Schneck, Janelle Fox, Rajeev Chaudhry, Glenn Cannon, Valentina Grajales, Avinash Maganty, Jeffrey Villanueva, Francis Schneck, Glenn Cannon, Paul Rusilko, Rajeev Chaudhry, Jeffrey Villanueva, Benjamin Pifer, Marc Colaco, Valentina Grajales, Omar Ayyash, Rajeev Chaudhry, Francis Schneck, Glenn Cannon, Janelle Fox, Jin Kyu (Justin) Kim, Armando Lorenzo, Luschman Raveendran, Michael Chua, Jessica Ming, Walid Farhat, Martin Koyle, Alexander Koven, Fardod O’Kelly, Ali El-Ghazzaoui, Jacob Langer, David Levin, Aubie Diamond, Yisroel Goldstein, Ezriel Reichman, Martin Koyle, Marc Colaco, Jeffrey Villanueva, Francis Schneck, Glenn Cannon, Janelle Fox, Marc Peretti, Rajeev Chaudhry, Joshua White, Landan MacDonald, Matthew Lowe, Dawn MacLellan, Rodrigo Romao, Michael Ernst, Nicole Belko, Teresa Danforth, Ellen Lutnick, Kyle Waisanen, Kevin Pranikoff, Kathryn Scott, Priyanka Kancherla, Garrett Smith, Matthew Mason, Anthony Tracey, Shady Garas, David Grynspan, Trustin Domes, Melise Keays, Julia Yu, Nicole Alavi-Dunn, Zafardjan Dalimov, John Bodkin, Anup Shah, Avinash Maganty, Paul Rusilko, Laura Donnelly, Feustel Paul, Cangero Theodore, Barry Kogan, Ahmed Elsayed, Umar Iqbal, Zhe Jing, Lee Richstone, Andrew Wagner, Bertram Yuh, Juan Palou, Eric Kim, Alexandre Mottrie, Thomas Maatman, Morgan Roupret, Derya Balbay, Carl Wijburg, Koon Rha, Franco Gaboardi, Michael Stockle, Prokar Dasgupta, Muhammad Shamim Khan, Peter Wiklund, James Peabody, Jihad Kaouk, Mani Menon, Ahmed Hussein, Gurkamal Chatta, Khurshid Guru, Kevin Carnes, Ashar Ata, Theodore Cangero, Badar Mian, Ahmed Hussein, Ahmed Elsayed, Mohammad Durrani, Umar Iqbal, Eduardo Cortes Gomez, Zhe Jing, Joseph Cilento, Lucas Kanestrin, Sean Gibson, Michael Mostowy, Alexander Yunke, Bernadette Zumpano, Sena Arman, Prashant Singh, Tang Li, Liu Song, Gary Smith, Khurshid Guru, Valentina Grajales, Nathan Hale, Jonathan Yabes, Robert Turner, Mina Fam, Lindsay Sabik, Jeffrey Gingrich, Benjamin Davies, Bruce Jacobs, Jathin Bandari, Sandra Kim, Rodney Breau, Ranjeeta Mallick, Anil Kapoor, Bhindi Bimal, Alan So, Antonio Finelli, Simon Tanguay, Frederic Pouliot, Adrian Fairey, Luke Lavallée, Ranjena Maloni, Ricardo Rendon, Thomas Osinski, Timothy Campbell, Jacob Gantz, Benjamin Nelson, Changyong Feng, Edward Messing, Ahmed Elsayed, Zhe Jing, Umar Iqbal, Deniz Demirbas, Mohammad Durrani, Kristopher Atwood, Joseph Cilento, Zafardjan Dalimov, Jennifer Osei, Sean Gibson, Michael Mostowy, Amylisa Christophe, Ahmed Hussein, Khurshid Guru, Ahmed Elsayed, Sean Gibson, Umar Iqbal, Zhe Jing, Lee Richstone, Andrew Wagner, Bertram Yuh, Juan Palou, Ahmed Aboumohamed, Eric Kim, Alexandre Mottrie, Morgan Roupret, Ketan Badani, Derya Balbay, Carl Wijburg, John Kelly, Koon Rha, Franco Gaboardi, Michael Stockle, Prokar Dasgupta, Muhammad Shamim Khan, Vassilis Poulakis, Peter Wiklund, James Peabody, Jihad Kaouk, Mani Menon, Ahmed Hussein, Khurshid Guru, Michael Mostowy, Ahmed Elsayed, Sadat Ozair, Mohammad Durrani, Umar Iqbal, Jennifer Osei, Zhe Jing, Alexander Yunke, Joseph Cilento, Blanka Kozma, Shikha Shelat, Lucas Kanestrin, Ahmed Hussein, Khurshid Guru, Mofarej Al-Hogbani, Jérémie Duguay, Philippe Joubert, Ricardo Rendon, Nicolas Power, Martine Périgny, Paul Toren, Stewart Whalen, Ricardo A. Rendon, David G. Bell, Morgan Macdonald, Jon Duplisea, Ashley R. Cox, Gregory G. Bailly, Ross Mason, Zafardjan Dalimov, Ahmed Elsayed, Umar Iqbal, Ahmed Hussein, Khurshid Guru, Ahmed Elsayed, Umar Iqbal, Zhe Jing, Jennifer Osei, Lee Richstone, Andrew Wagner, Bertram Yuh, Juan Palou, Eric Kim, Alex Mottrie, Derya Balbay, Carl Wijburg, Morgan Roupret, Ketan Badani, Franco Gaboardi, Michael Stockle, Prokar Dasgupta, Muhammad Shamim Khan, Peter Wiklund, Jihad Kaouk, James Peabody, Mani Menon, Ahmed Hussein, Khurshid Guru, Ahmed Elsayed, Amir Khan, Zhe Jing, Umar Iqbal, Jennifer Osei, Lee Richstone, Andrew Wagner, Bertram Yuh, Juan Palou, Eric Kim, Alexandre Mottrie, Thomas Maatman, Morgan Roupret, Ketan Badani, Derya Balbay, Ahmed Aboumohamed, Franco Gaboardi, Michael Stockle, Prokar Dasgupta, Muhammad Shamim Khan, Peter Wiklund, Jihad Kaouk, James Peabody, Mani Menon, Ahmed Hussein, Khurshid Guru, Carl Wijburg, Jennifer Osei, Ahmed Elsayed, Umar Iqbal, Zhe Jing, Naif Aldhaam, Mohammad Durrani, Bernadette Zumpano, Melissa Hopkins, Shikha Shelat, Joseph Ci lento, Amanda Pasquini, Zafardjan Dalimov, Sena Arman, Ahmed Hussein, Khurshid Guru, Valentina Grajales, Anup Shah, Kelly Pekala, Zhaojun Sun, Kirsten Eom, Benjamin Davies, Lindsay Sabik, Bruce Jacobs, Kadeen Forrest, Kathryn Scott, Rakesh Khanna, Shreyas Gandhi, Alex Koziarz, Jason Lee, John Perna, Rakesh Khanna, Kelly Pekala, Anup Shah, Valentina Grajales, Zhaojun Sun, Kirsten Eom, Benjamin Davies, Jie Li, Bruce Jacobs, Lindsay Sabik, Stephanie Gleicher, Natasha Ginzburg, Timothy Byler, James Ross, Humberto Vigil, Conrad Maciejewski, Blayne Welk, Ranjeeta Mallik, Rodney Breau, Duane Hickling, Chloe Shenk, Fei Lian, Darren Gemoets, Gillian Wolff, Kathryn Scott, Alexandr Pinkhasov, Elizabeth Ferry, Chris Bitcon, Ashley Cox, Kyle Waisanen, Adam Russon, Kevin Pranikoff, Ronald Swerdloff, Christina Wang, Marc Gittelman, Jed Kaminetsky, David Albala, James Longstreth, Robert Dudley, David-Dan Nguyen, Maya Marchese, Eugene B. Cone, Marco Paciotti, Shehzad Basaria, Naeem Bhojani, Quoc-Dien Trinh, Matthew Beamer, J. Curtis Nickel, Sergey Kravchick, Stephanie Gleicher, Timothy Byler, David Sikule, Charles Welliver, Alessia Di Carlo, Michael Leveridge, Thomas McGregor, Mark Arthur, Charles Welliver, Alexis Steinmetz, Ronald Rabinowitz, Zafardjan Dalimov, Jordan S. Levine, Julia S. Yu, Nicole Alavi-Dunn, K. Kent Chevli, Uday Mann, Amanda Eng, Rachel Wong, Zack Li, Ruben Blachman-Braun, Premal Patel, Jordan Levine, Zafardjan Dalimov, Julia Yu, Jinwei Hu, Teresa Danforth, Zafardjan Dalimov, Julia S. Yu, Jordan S. Levine, K. Kent Chevli, Rachel Melnyk, Patrick Saba, Tyler Holler, Prabhakar Mithal, Philip Rappold, Guan Wu, Jimena Cubillos, Hani Rashid, Jean Joseph, Ahmed Ghazi, David-Dan Nguyen, Kevin C. Zorn, Dean S. Elterman, Naeem Bhojani, Somayeh Shafiei, Ahmed Elsayed, Ahmed Hussein, Khurshid Guru, David-Dan Nguyen, Marco Paciotti, Quoc-Dien Trinh, Matthew Mossanen, David-Dan Nguyen, Dean Elterman, Kevin C. Zorn, Naeem Bhojani, Michael Hughes, Dominic Labella, Scott Wiener, Thomas Sanford, Avril Lusty, Isabelle Raîche, Michael Witthaus, Patrick Saba, Rachel Melnyk, Divya Ajay, Gareth Warren, Ricardo Munarriz, Ahmed Ghazi, Thomas Osinski, Rachel Melnyk, Tyler Holler, Janis Intoy, Katherine Cameron, Susan Greenman, Patrick Saba, Richard Grinstead, David Lee, Rajat Jain, Ashwani Sharma, Michele Rucci, Ahmed Ghazi, Jeannette Johnstone, Adam Gabara, Naji Touma, David Kozminski, Barry Kogan, Uday Mann, Jasmir G. Nayak, Premal Patel, Avril Lusty, Isabelle Raîche, Gregory Hosier, Thomas McGregor, Darren Beiko, Gregory Tasian, Christopher Booth, Marlo Whitehead, D. Robert Siemens, Chinmayee Katragadda, Alexis Steinmetz, Alexander Cranwell, Rajat Jain, Avinash Maganty, Allan Wolfson, Pamela Burrows, Ziya Kirkali, Andrew Meltzer, Stephen Jackman, David-Dan Nguyen, Jack W. Luo, Xing H. Lu, Jonathan R.Z. Lim, Kymora B. Scotland, Seth K. Bechis, Roger L. Sur, Stephen Y. Nakada, Jodi A. 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Albala, Michael Donovan, Mikkel Noerholm, Vasisht Tadigotla, Sonia Kumar, Phillipp Torkler, Grannum Sant, Jason Alter, Johan Skog, Thomas Osinski, Kim Solomon, Anthony Mirabella, Jonathan Bloom, Thomas Frye, Gary Hollenberg, Eric Weinberg, Ronald Tutrone, David Albala, Michael Donovan, Phillipp Torkler, Vasisht Tadigotla, Mikkel Noerholm, Johan Skog, James McKiernan, James Mohler, Jennifer Cullen, Julie Lynch, Eric Klein, Stephen Van Den Eeden, Peter Carroll, Dejan Knezevic, Thomas Farrington, Jeffrey Lawrence, Ruixiao Lu, David M. Albala, Michael Donovan, Mikkel Noerholm, Vasisht Tadigotla, Sonia Kumar, Phillipp Torkler, Grannum Sant, Jason Alter, Johan Skog, Dominik Deniffel, Emmanuel Salinas, Marc Ientilucci, Andrew Evans, Neil Fleshner, Sangeet Ghai, Robert J. Hamilton, Ants Toi, Theodorus van der Kwast, Alexandre Zlotta, Antonio Finelli, Masoom Haider, Nathan Perlis, Judd Moul, Stuart Atkinson, Deborah Boldt-Houle, Richard Harris, Marie-Hélène Guertin, Karine Robitaille, Jean-François Pelletier, Molière Nguile Makao, Helene Hovington, Caroline Léger, Yves Fradet, Arnaud Marien, Frederic Pouliot, Louis Lacombe, Rabi Tiguert, Yves Caumartin, Thierry Dujardin, Paul Toren, Michele Lodde, Étienne Racine, Dominique Trudel, Martine Périgny, Thierry Duchesne, Josée Savard, Pierre Julien, Isabelle Bairati, Vincent Fradet, Adel Arezki, Iman Sadri, Ahmed S. Zakaria, Félix Couture, David-Dan Nguyen, Pierre Karakiewicz, Kevin C. Zorn, Adam Sharbaugh, Ronald Benoit, Ryan Smith, Christopher Houser, Sushil Beriwal, Hanane Moussa, Lamoussa Diabaté, Karine Robitaille, Laurence Bettan, Molière Nguile-Makao, Hélène Hovington, Fred Saad, Michel Carmel, Armen Aprikian, BIOCaPPE Network, Benoit Lamarche, Pierre Julien, Yves Fradet, Vincent Fradet, Samuel Fradet, Karine Robitaille, Jean-François Pelletier, Narcisse Singbo, Louis Lacombe, Frédéric Pouliot, Paul Toren, Yves Fradet, Michele Lodde, Rabi Tiguert, Thierry Dujardin, Josée Savard, Isabelle Bairati, Vincent Fradet, Roxane Tourigny, Hanane Moussa, Karine Robitaille, Fred Saad, Michel Carmel, Armen Aprikian, Yves Fradet, BIOCaPPE-GRéPEC Network, Vincent Fradet, Adam Sharbaugh, Ronald Benoit, Joshua Rodriguez-Lopez, Ankur Patel, Sushil Beriwal, Ryan Smith, David Albala, John Bennett, Tamer Aboushwareb, Natalie Lau, Melissa Stoppler, Aaron Katz, James McKiernan, David Albala, Ronald Tutrone, Michael Donovan, Phillipp Torkler, Mikkel Noerholm, Jason Alter, Johan Skog, Joshua White, Gabriela Ilie, Greg Bailly, David Bell, Robert Rutledege, Charlie Gillis, Thomas Southall, Michelle Anderson, Jennifer Young, Richard Hewitt, Matthew Andrews, Garrett Smith, Stephanie Gleicher, Joseph Jacob, Gennady Bratslavsky, Timothy Byler, Jason Alter, David Albala, Michael Donovan, Phillipp Torkler, Mikkel Noerholm, Johan Skog,

Can Urol Assoc J (Canadian Urological Association journal = Journal de l'Association des urologues du Canada)
[2020, 14(9 Suppl 3):S169-S232]

Cited: 0 times

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A Decision Aide for the Risk Stratification of GU Cancer Patients at Risk of SARS-CoV-2 Infection, COVID-19 Related Hospitalization, Intubation, and Mortality.

Dara J Lundon, Brian D Kelly, Devki Shukla, Damien M Bolton, Peter Wiklund, Ash Tewari,

Treatment decisions for both early and advanced genitourinary (GU) malignancies take into account the risk of dying from the malignancy as well as the risk of death due to other causes such as other co-morbidities. COVID-19 is a new additional and immediate risk to a patient's morbidity and mortality and ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(9):]

Cited: 1 time

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Ureteral location is associated with survival outcomes in upper tract urothelial carcinoma: A population-based analysis.

Alessandro Veccia, Alessandro Antonelli, Alberto Martini, Ugo Falagario, Giuseppe Carrieri, Mayer B Grob, Georgi Guruli, Claudio Simeone, Peter Wiklund, Francesco Porpiglia, Riccardo Autorino,

<h4>Objectives</h4>To evaluate the prognostic value of tumor location in patients with upper tract urothelial carcinoma.<h4>Methods</h4>Within the Surveillance, Epidemiology and End Results Incidence Database, 6619 upper tract urothelial carcinoma cases were identified, including 3719 confined to the renal pelvis and 2971 to the ureter. Predictors of surgical technique (kidney sparing surgery ... Read more >>

Int J Urol (International journal of urology : official journal of the Japanese Urological Association)
[2020, 27(11):966-972]

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Re-establishing the Role of Robot-assisted Radical Cystectomy After the 2020 EAU Muscle-invasive and Metastatic Bladder Cancer Guideline Panel Recommendations.

Francesco Montorsi, Marco Bandini, Alberto Briganti, Prokar Dasgupta, Andrea Gallina, Michele Gallucci, Inderbir S Gill, Khurshid A Guru, Ashok Hemal, Mani Menon, Marco Moschini, Declan G Murphy, Dipen J Parekh, Hiten D Patel, Hiten R H Patel, Michael Stöckle, Ash K Tewari, Carl J Wijburg, Peter Wiklund, Timothy G Wilson, Alexandre Mottrie, ,

The EAU guidelines panel on muscle-invasive and metastatic bladder cancer (MIBC) recently recommended open radical cystectomy (ORC) as the best surgical approach for MIBC patients. We critically re-examine the indications for considering ORC as the first choice over robot-assisted radical cystectomy. To the best of our knowledge, this is not ... Read more >>

Eur Urol (European urology)
[2020, 78(4):489-491]

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Interactive effects of aging and aerobic capacity on energy metabolism-related metabolites of serum, skeletal muscle, and white adipose tissue

Haihui Zhuang, Sira Karvinen, Xiaobo Zhang, Xiaowei Ojanen, Timo Törmakangas, Vidya Velagapudi, Markku Alen, Steven Britton, Lauren Koch, Heikki Kainulainen, Sulin Cheng, Petri Wiklund,

<h4>ABSTRACT</h4> Aerobic capacity is a strong predictor of longevity. With aging, aerobic capacity decreases concomitantly with changes in whole body metabolism leading to increased disease risk. To address the role of aerobic capacity, aging and their interaction on metabolism, we utilized rat models of low and high intrinsic aerobic capacity ... Read more >>

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