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Delayed greening in phosphorus-efficient Hakea prostrata (Proteaceae) is a photoprotective and nutrient-saving strategy.

Thirumurugen Kuppusamy, Dorothee Hahne, Kosala Ranathunge, Hans Lambers, Patrick M Finnegan,

Hakea prostrata R.Br. (Proteaceae) shows a 'delayed greening' strategy of leaf development characterised by reddish young leaves that become green as they mature. This trait may contribute to efficient use of phosphorus (P) during leaf development by first investing P in the development of leaf structure followed by maturation of ... Read more >>

Funct Plant Biol (Functional plant biology : FPB)
[2021, 48(2):218-230]

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Metabolic acclimation supports higher aluminium-induced secretion of citrate and malate in an aluminium-tolerant hybrid clone of Eucalyptus.

Wannian Li, Patrick M Finnegan, Qin Dai, Dongqiang Guo, Mei Yang,

<h4>Background</h4>Eucalyptus is the main plantation wood species, mostly grown in aluminized acid soils. To understand the response of Eucalyptus clones to aluminum (Al) toxicity, the Al-tolerant Eucalyptus grandis × E. urophylla clone GL-9 (designated "G9") and the Al-sensitive E. urophylla clone GL-4 (designated "W4") were employed to investigate the production ... Read more >>

BMC Plant Biol (BMC plant biology)
[2021, 21(1):14]

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Metabolic acclimation supports higher aluminium-induced secretion of citrate and malate in an aluminium-tolerant hybrid clone of Eucalyptus

Wannian Li, Patrick Finnegan, Qin Dai, Dongqiang Guo, Mei Yang,

<h4>Background: </h4> Eucalyptus is the main plantation wood species, mostly grown in aluminized acid soils. To understand the response of Eucalyptus clones to aluminum (Al) toxicity, the Al-tolerant Eucalyptus grandis × E. urophylla clone GL-9 (designated “G9”) and the Al-sensitive E. urophylla clone GL-4 (designated “W4”) were employed to investigate ... Read more >>

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Comparison of Soaking Corms with Moringa Leaf Extract Alone or in Combination with Synthetic Plant Growth Regulators on the Growth, Physiology and Vase Life of Sword Lily.

Faisal Zulfiqar, Adnan Younis, Patrick M Finnegan, Antonio Ferrante,

Gladiolus is in demand worldwide as a cut-flower or landscaping plant, because of its superior commercial and ornamental value. Application of plant-based biostimulants has gained interest in the horticulture industry as an innovative and promising approach to ensure enhanced and sustainable yields along with better product quality. The influence of ... Read more >>

Plants (Basel) (Plants (Basel, Switzerland))
[2020, 9(11):]

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Spontaneous Urinoma Without Trauma or Obstruction in a 64-Year-Old Female.

Patrick S Finnegan, Thomas Proctor, Brian Pennington,

A 64-year-old female presented to the ED with severe abdominal pain. Initially it was suspected to be spontaneous aortic rupture or dissection. Contrasted CT imaging studies did not identify aneurysm and dissection, but did identify a concerning, confounding, and curious collection of fluid in the upper right quadrant. Angiography imaging ... Read more >>

Cureus (Cureus)
[2020, 12(7):e9241]

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Direct to Consumer Telemedicine: Is Healthcare From Home Best?

Suzanne G Bollmeier, Emily Stevenson, Patrick Finnegan, Scott K Griggs,

Direct-to-consumer (DTC) telemedicine is increasingly popular and enables patients to obtain medical advice and treatment via electronic media (e.g., computer, telephone, or smartphone) without a prior doctor-patient relationship. Convenience, accessibility, and home delivery make DTC telemedicine attractive to patients. Concerns about DTC telemedicine include: a lack of regulation, transparency, and ... Read more >>

Mo Med (Missouri medicine)
[2020, 117(4):303-309]

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1447. Ex Vivo Human Bladder Tissue Model to Evaluate Lactobacillus-Containing Formulations as Preventative Treatment Against Common Urogenital Pathogens

Danielle Nicklas, Patrick Finnegan, Zach Siler, Marnie Peterson, Shantha Sarangapani,

Abstract Background Urinary tract infections (UTIs) are common bacterial infections in adults, and catheter-associated UTIs are the most common nosocomial infection. The rise of multidrug-resistant organisms and an increased focus on antibiotic stewardship has influenced the development of novel treatments against such infections, and there is growing interest in the ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S528-S528]

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One thousand plant transcriptomes and the phylogenomics of green plants.

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Green plants (Viridiplantae) include around 450,000-500,000 species<sup>1,2</sup> of great diversity and have important roles in terrestrial and aquatic ecosystems. Here, as part of the One Thousand Plant Transcriptomes Initiative, we sequenced the vegetative transcriptomes of 1,124 species that span the diversity of plants in a broad sense (Archaeplastida), including green ... Read more >>

Nature (Nature)
[2019, 574(7780):679-685]

Cited: 43 times

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The contrasting leaf functional traits between a karst forest and a nearby non-karst forest in south-west China.

Pei-Li Fu, Shi-Dan Zhu, Jiao-Lin Zhang, Patrick M Finnegan, Yan-Juan Jiang, Hua Lin, Ze-Xin Fan, Kun-Fang Cao,

Karst and non-karst forests occur in the same region in south-west China, but the soil water and mineral nutrients availability are different between the forests. Our hypothesis was that the leaves of karst trees would be better adapted to dry, nutrient-poor conditions than those of trees in a nearby non-karst ... Read more >>

Funct Plant Biol (Functional plant biology : FPB)
[2019, 46(10):907-915]

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Mechanisms underlying enhanced Cd translocation and tolerance in roots of Populus euramericana in response to nitrogen fertilization.

Junyu Song, Patrick M Finnegan, Wenhui Liu, Xiang Li, Jean W H Yong, Jiuting Xu, Qi Zhang, Yuxin Wen, Kexin Qin, Jinze Guo, Ting Li, Chang Zhao, Yi Zhang,

A pot experiment was conducted to evaluate how nitrogen (N) availability influences cadmium (Cd) absorption, translocation and stress tolerance in roots of Populus euramericana. Seedling growth was sensitive to N deficiency, but it was unaltered by Cd exposure. Cadmium absorption by roots was promoted by N deficiency, resulting in a ... Read more >>

Plant Sci (Plant science : an international journal of experimental plant biology)
[2019, 287:110206]

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Responses of foliar phosphorus fractions to soil age are diverse along a 2 Myr dune chronosequence.

Li Yan, Xinhou Zhang, Zhongming Han, Jiayin Pang, Hans Lambers, Patrick M Finnegan,

Plants respond to soil phosphorus (P) availability by adjusting leaf P among inorganic P (Pi) and organic P fractions (nucleic acids, phospholipids, small metabolites and a residual fraction). We tested whether phylogenetically divergent plants in a biodiversity hotspot similarly adjust leaf P allocation in response to P limitation by sampling ... Read more >>

New Phytol (The New phytologist)
[2019, 223(3):1621-1633]

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Mechanisms underlying enhanced Cd translocation and tolerance in roots of Populus euramericana in response to nitrogen fertilization

Junyu Song, Patrick M Finnegan, Wenhui Liu, Xiang Li, Jean W H Yong, Jiuting Xu, Qi Zhang, Yuxin Wen, Kexin Qin, Ting Li, Chang Zhao, Yi Zhang,

A pot experiment was conducted to evaluate how nitrogen (N) availability influences cadmium (Cd) absorption, translocation and stress tolerance in roots of Populus euramericana. Seedling growth was sensitive to N deficiency, but it was unaltered by Cd exposure. Cadmium absorption by roots was promoted by N deficiency, resulting in a ... Read more >>

Plant Sci (Plant science : an international journal of experimental plant biology)
[2019, :Not Available]

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Cross-Platform Comparison of Computer-assisted Image Analysis Quantification of In Situ mRNA Hybridization in Investigative Pathology.

Timothy R Holzer, Jeffrey C Hanson, Erin M Wray, Jason A Bailey, Kim R Kennedy, Patrick R Finnegan, Aejaz Nasir, Kelly M Credille,

Although availability of automated platforms has proliferated, there is no standard practice for computer-assisted generation of scores for mRNA in situ hybridization (ISH) visualized by brightfield microscopic imaging on tissue sections. To address this systematically, an ISH for peptidylprolyl isomerase B (PPIB) (cyclophilin B) mRNA was optimized and applied to ... Read more >>

Appl Immunohistochem Mol Morphol (Applied immunohistochemistry & molecular morphology : AIMM)
[2019, 27(1):15-26]

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How Does Evolution in Phosphorus-Impoverished Landscapes Impact Plant Nitrogen and Sulfur Assimilation?

M Asaduzzaman Prodhan, Patrick M Finnegan, Hans Lambers,

Phosphorus (P) fertilisers, made from rock phosphate, are used to attain high crop yields. However, rock phosphate is a finite resource and excessive P fertilisers pollute our environment, stressing the need for more P-efficient crops. Some Proteaceae have evolved in extremely P-impoverished environments. One of their adaptations is to curtail ... Read more >>

Trends Plant Sci (Trends in plant science)
[2019, 24(1):69-82]

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Video-tube thoracostomy in trauma resuscitation: A pilot study.

P Finnegan, M Fitzgerald, D Smit, K Martin, J Mathew, D Varma, A Lim, S Scott, K Williams, Y Kim, B Mitra,

BACKGROUND:Complications related to incorrect positioning of tube thoracostomy (TT) have been reported to be as high as 30%. The aim of this study was to assess the feasibility of flexible videoscope guided placement of a pre-loaded chest tube, permitting direct intrapleural visualization and placement (Video-Tube Thoracostomy [V-TT]). METHODS:A prospective, single ... Read more >>

Injury (Injury)
[2019, 50(1):90-95]

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Attitudes and Uptake of Seasonal Influenza Vaccination for Health Service Executive (HSE) Staff.

K I Quintyne, E Daly, E Brabazon, P Finnegan, P Kavanagh,

Aims Annual seasonal influenza (flu) vaccination is recommended for all healthcare workers (HCW) in the Health Service Executive (HSE) in Ireland. This is to reduce the risk of HCW contracting the flu and onward transmission to their patients. HCW uptake remains less than ideal, despite extensive seasonal influenza campaigns and vaccination ... Read more >>

Ir Med J (Irish medical journal)
[2018, 111(5):749]

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Ceragenins are active against drug-resistant Candida auris clinical isolates in planktonic and biofilm forms.

Marjan M Hashemi, John Rovig, Brett S Holden, Maddison F Taylor, Scott Weber, John Wilson, Brian Hilton, Aaron L Zaugg, Samuel W Ellis, Connor D Yost, Patrick M Finnegan, Charles K Kistler, Elizabeth L Berkow, Shenglou Deng, Shawn R Lockhart, Marnie Peterson, Paul B Savage,

Background:Candida auris has emerged as a serious threat to human health. Of particular concern are the resistance profiles of many clinical isolates, with some being resistant to multiple classes of antifungals. Objectives:Measure susceptibilities of C. auris isolates, in planktonic and biofilm forms, to ceragenins (CSAs). Determine the effectiveness of selected ... Read more >>

J Antimicrob Chemother (The Journal of antimicrobial chemotherapy)
[2018, 73(6):1537-1545]

Cited: 6 times

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Plant functional group controls litter decomposition rate and its temperature sensitivity: An incubation experiment on litters from a boreal peatland in northeast China.

Rong Mao, Xinhou Zhang, Changchun Song, Xianwei Wang, Patrick M Finnegan,

In boreal peatlands, litter decomposition plays an important role in modulating ecosystem carbon (C) cycling and nutrient turnover. However, how climate warming and plant functional group interact to affect litter decomposition is still unclear in these ecosystems. Here, we collected fresh litters of six plant functional groups (nitrogen (N)-fixing species, ... Read more >>

Sci Total Environ (The Science of the total environment)
[2018, 626:678-683]

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Straight leg elevation to rule out pelvic injury.

Caroline Bolt, Francis O'Keeffe, Pete Finnegan, Kristofer Dickson, De Villiers Smit, Mark C Fitzgerald, Biswadev Mitra,

<h4>Objective</h4>Pelvic x-ray is frequently used as a screening tool during initial assessment of injured patients. However routine use in the awake and alert blunt trauma patient may be questioned due to low yield. We propose a clinical tool that may avoid unnecessary imaging by examining whether the ability to straight ... Read more >>

Injury (Injury)
[2018, 49(2):279-283]

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Tight control of sulfur assimilation: an adaptive mechanism for a plant from a severely phosphorus-impoverished habitat.

M Asaduzzaman Prodhan, Ricarda Jost, Mutsumi Watanabe, Rainer Hoefgen, Hans Lambers, Patrick M Finnegan,

Hakea prostrata (Proteaceae) has evolved in extremely phosphorus (P)-impoverished habitats. Unlike species that evolved in P-richer environments, it tightly controls its nitrogen (N) acquisition, matching its low protein concentration, and thus limiting its P requirement for ribosomal RNA (rRNA). Protein is a major sink for sulfur (S), but the link ... Read more >>

New Phytol (The New phytologist)
[2017, 215(3):1068-1079]

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Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa.

Aaron N Gillman, Laura M Breshears, Charles K Kistler, Patrick M Finnegan, Victor J Torres, Patrick M Schlievert, Marnie L Peterson,

<i>Staphylococcus aureus</i> (<i>S. aureus</i>) produces many different exotoxins including the gamma-toxins, HlgAB and HlgCB. Gamma-toxins form pores in both leukocyte and erythrocyte membranes, resulting in cell lysis. The genes encoding gamma-toxins are present in most strains of <i>S. aureus,</i> and are commonly expressed in clinical isolates recovered from menstrual Toxic ... Read more >>

Toxins (Basel) (Toxins)
[2017, 9(7):]

Cited: 3 times

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Tight control of nitrate acquisition in a plant species that evolved in an extremely phosphorus-impoverished environment.

M Asaduzzaman Prodhan, Ricarda Jost, Mutsumi Watanabe, Rainer Hoefgen, Hans Lambers, Patrick M Finnegan,

Hakea prostrata (Proteaceae) has evolved in an extremely phosphorus (P)-limited environment. This species exhibits an exceptionally low ribosomal RNA (rRNA) and low protein and nitrogen (N) concentration in its leaves. Little is known about the N requirement of this species and its link to P metabolism, despite this being the ... Read more >>

Plant Cell Environ (Plant, cell & environment)
[2016, 39(12):2754-2761]

Cited: 5 times

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Single objective light-sheet microscopy for high-speed whole-cell 3D super-resolution.

Marjolein B M Meddens, Sheng Liu, Patrick S Finnegan, Thayne L Edwards, Conrad D James, Keith A Lidke,

We have developed a method for performing light-sheet microscopy with a single high numerical aperture lens by integrating reflective side walls into a microfluidic chip. These 45° side walls generate light-sheet illumination by reflecting a vertical light-sheet into the focal plane of the objective. Light-sheet illumination of cells loaded in ... Read more >>

Biomed Opt Express (Biomedical optics express)
[2016, 7(6):2219-2236]

Cited: 18 times

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Sensitivity of jarrah (Eucalyptus marginata) to phosphate, phosphite, and arsenate pulses as influenced by fungal symbiotic associations.

Khalil Kariman, Susan J Barker, Ricarda Jost, Patrick M Finnegan, Mark Tibbett,

Many plant species adapted to P-impoverished soils, including jarrah (Eucalyptus marginata), develop toxicity symptoms when exposed to high doses of phosphate (Pi) and its analogs such as phosphite (Phi) and arsenate (AsV). The present study was undertaken to investigate the effects of fungal symbionts Scutellospora calospora, Scleroderma sp., and Austroboletus ... Read more >>

Mycorrhiza (Mycorrhiza)
[2016, 26(5):401-415]

Cited: 4 times

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Heartwood-specific transcriptome and metabolite signatures of tropical sandalwood (Santalum album) reveal the final step of (Z)-santalol fragrance biosynthesis.

Jose M Celedon, Angela Chiang, Macaire M S Yuen, Maria L Diaz-Chavez, Lufiani L Madilao, Patrick M Finnegan, Elizabeth L Barbour, Jörg Bohlmann,

Tropical sandalwood (Santalum album) produces one of the world's most highly prized fragrances, which is extracted from mature heartwood. However, in some places such as southern India, natural populations of this slow-growing tree are threatened by over-exploitation. Sandalwood oil contains four major and fragrance-defining sesquiterpenols: (Z)-α-santalol, (Z)-β-santalol, (Z)-epi-β-santalol and (Z)-α-exo-bergamotol. ... Read more >>

Plant J (The Plant journal : for cell and molecular biology)
[2016, 86(4):289-299]

Cited: 16 times

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