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Author Ozlem Demirpence

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High mobility group box-1 levels in schizophrenia: Potential biomarker of remission phase.

Nuryil Yilmaz, Zekeriya Yelboga, Yavuz Yilmaz, Ozlem Demirpence,

<b>Background:</b> Schizophrenia is a chronic mental disorder, characterized byacute exacerbation and remission phases. Immune system has a role in the pathophysiology of schizophrenia. High mobility group box-1 (HMGB-1) is a macrophage secreted protein activating immune cells to produce cytokines. The aim of this study was to evaluate HMGB-1 levels among ... Read more >>

J Med Biochem (Journal of medical biochemistry)
[2021, 40(3):295-301]

Cited: 0 times

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High-sensitivity C-reactive protein and high mobility group box-1 levels in Parkinson's disease.

Aslıhan Baran, Mahmut Bulut, Mehmet Cemal Kaya, Özlem Demirpençe, Bünyamin Sevim, Eşref Akıl, Sefer Varol,

Various immunologic and inflammatory factors are contributed to pathogenesis of Parkinson's disease (PD). High mobility group box-1 (HMGB1) is a protein that plays certain roles in inflammation, DNA repair, transcription, somatic recombination, cell differentiation, cell migration, neuronal development, and neurodegeneration. The aim of the present study was to evaluate the ... Read more >>

Neurol Sci (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2019, 40(1):167-173]

Cited: 4 times

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İbrahim Gül, Oğuzhan Yücel, Abdullah Zararsız, Özlem Demirpençe, Hasan Yücel, Ali Zorlu, Mehmet Birhan Yılmaz,

Anatol J Cardiol (Anatolian journal of cardiology)
[2018, 19(3):228-229]

Cited: 0 times

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Prognostic role of soluble suppression of tumorigenicity-2 on cardiovascular mortality in outpatients with heart failure.

İbrahim Gül, Oğuzhan Yücel, Abdullah Zararsız, Özlem Demirpençe, Hasan Yücel, Ali Zorlu, Mehmet Birhan Yılmaz,

<h4>Objective</h4>Soluble suppression of tumorigenicity-2 (sST2), a member of the interleukin 1 receptor family, is increased in mechanical stress conditions and is produced by cardiomyocytes and cardiac fibroblasts. Elevated sST2 level is associated with the prognosis of acute coronary syndrome, pulmonary arterial hypertension, and acute and chronic heart failure (HF). In ... Read more >>

Anatol J Cardiol (Anatolian journal of cardiology)
[2017, 18(3):200-205]

Cited: 6 times

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Decreased Chitotriosidase Activity and Levels in Familial Mediterranean Fever.

Halef Okan Doğan, Ahmet Omma, Turan Turhan, Nihal Boğdaycıoğlu, Yaşar Karaaslan, Hayrettin Yavuz, Özlem Demirpençe, Hüseyin Aydın, Sevtap Bakır,

Different studies have demonstrated changes in chitotriosidase (ChT) activity and concentrations in multiple diseases. However, changes in ChT activity and concentrations have not been concurrently evaluated in patients with Familial Mediterranean Fever (FMF). In this study, we analyzed the changes in serum ChT activity and concentrations in patients with FMF. ... Read more >>

J Korean Med Sci (Journal of Korean medical science)
[2016, 31(12):1902-1906]

Cited: 3 times

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Examination of the Relationship between Umbilical Cord Blood Gas Values and Hearing Function in Neonates.

Kasım Durmuş, Çağlar Yıldız, Özlem Demirpençe, Ömer Tamer Doğan, Ali Çetin, Emine Elif Altuntaş,

Objective:The aim of the present study was to examine the relationship between the results of the transient otoacoustic emission (TEOAE) test used in neonatal hearing screening and the results of the umbilical cord blood (UCB) analysis in neonates. Methods:This retrospective study included 209 neonates born in the obstetric unit at ... Read more >>

Turk Arch Otorhinolaryngol (Turkish archives of otorhinolaryngology)
[2017, 55(2):72-76]

Cited: 0 times

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Presepsin Levels of Patients with Crimean-Congo Hemorrhagic Fever.

Özlem Demirpençe, Halef Okan Doğan, Serpil Erşan, Mehtap Şahin, Hasan Şahin, Mehmet Bakır,

Levels of presepsin (a soluble cluster of differentiation subtype 14 [CD14]) are thought to increase in cases of bacterial infection. CD14 has also been found to play a role in the pathogenesis of various viral diseases. Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic arboviral infection. Our study focuses on presepsin ... Read more >>

Jpn J Infect Dis (Japanese journal of infectious diseases)
[2016, 69(6):505-509]

Cited: 1 time

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Ovarian Reserve Assessment in Celiac Patients of Reproductive Age.

Erol Cakmak, Savas Karakus, Ozlem Demirpence, Banu Demet Coskun,

BACKGROUND This study aimed to investigate ovarian reserve in patients of reproductive age with Celiac disease (CD) using anti-Müllerian hormone (AMH) levels, antral follicle counts (AFCs), and ovarian volume. MATERIAL AND METHODS We included into this study 46 CD female patients and 40 healthy female subjects of reproductive age, ages ... Read more >>

Med Sci Monit (Medical science monitor : international medical journal of experimental and clinical research)
[2018, 24:1152-1157]

Cited: 1 time

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Serum levels of HMGB1 have a diagnostic role in metastatic renal cell cancer.

Ayşegül Kargı, Özlem Demirpençe, Şeyda Gündüz, Sevil Göktaş, Arsenal Sezgin Alikanoǧlu, Mustafa Yıldırım,

RCC constitutes approximately 90% of all renal malignancies and 2-3% of all malignant tumours in adults. In spite of the improvement in radiologic methods, nearly 30% of the early metastatic RCC patients are incidentally diagnosed. HMGB1 is an extracellular signalling molecule that plays a role both in inflammation and carcinogenesis. ... Read more >>

Cancer Biomark (Cancer biomarkers : section A of Disease markers)
[2016, 17(1):17-20]

Cited: 3 times

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Neutrophil-lymphocyte ratio in patients with major depressive disorder undergoing no pharmacological therapy.

Süleyman Demir, Abdullah Atli, Mahmut Bulut, Aslıhan Okan İbiloğlu, Mehmet Güneş, Mehmet Cemal Kaya, Özlem Demirpençe, Aytekin Sır,

Studies attempting to clarify the relationship between major depressive disorder (MDD) and the immune system have been increasing in recent years. It was reported that increased production of the main proinflammatory cytokines, such as interleukin-1, interleukin-6, and tumor necrosis factor-alpha, and that of acute phase reactants may play a role ... Read more >>

Neuropsychiatr Dis Treat (Neuropsychiatric disease and treatment)
[2015, 11:2253-2258]

Cited: 28 times

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The role of gender in patients with diffuse large B cell lymphoma treated with rituximab-containing regimens: a meta-analysis.

Mustafa Yıldırım, Vildan Kaya, Özlem Demirpençe, Semra Paydaş,

INTRODUCTION:Diffuse large B cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL). Although gender has not been included in prognostic systems, male gender has been found as a bad prognostic indicator in Hodgkin lymphoma, follicular lymphoma and chronic lymphocytic leukemia. The relationship between gender and prognosis is ... Read more >>

Arch Med Sci (Archives of medical science : AMS)
[2015, 11(4):708-714]

Cited: 6 times

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The role of high mobility group box 1 (HMGB1) in colorectal cancer.

Dinç Süren, Mustafa Yıldırım, Özlem Demirpençe, Vildan Kaya, Arsenal Sezgin Alikanoğlu, Nurullah Bülbüller, Mustafa Yıldız, Cem Sezer,

<h4>Background</h4>HMGB1, the most important member of the high mobility group box protein family, is a nuclear protein with different functions in the cell; it has a role in cancer progression, angiogenesis, invasion, and metastasis development. We studied the expression of HMGB1 and whether it is a prognostic factor in colorectal ... Read more >>

Med Sci Monit (Medical science monitor : international medical journal of experimental and clinical research)
[2014, 20:530-537]

Cited: 40 times

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Elevated Serum CD95/FAS and HIF-1α Levels, but Not Tie-2 Levels, May Be Biomarkers in Patients With Severe Endometriosis: A Preliminary Report.

Savas Karakus, Enver Sancakdar, Ozlem Akkar, Caglar Yildiz, Ozlem Demirpence, Ali Cetin,

<h4>Study objective</h4>To evaluate serum values of cluster of differentiation 95 (CD95/FAS), hypoxia-inducible factor 1-alpha (HIF-1α), and tyrosine kinase receptor 2 (Tie-2) as possible biomarkers of disease presence and severity in women with endometriosis, and to characterize the changes in these values in women with stage I/II and stage III/IV endometriosis.<h4>Design</h4>Prospective ... Read more >>

J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2016, 23(4):573-577]

Cited: 2 times

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Serum paraoxonase, TAS, TOS and ceruloplasmin in brucellosis.

Ozlem Demirpençe, Bünyamin Sevim, Mustafa Yıldırım, Nilhan Ayan Nurlu, Duygu Mert, Osman Evliyaoğlu,

<h4>Unlabelled</h4>It is possible that brucellosis may be related to increase free radical production and antioxidant depletion. Thus, in the present study we aimed to evaluate the oxidative status in patient with brucellosis and healthy controls.<h4>Methods</h4>This study includes the patients with brucellosis diagnosed by clinical findings and positive agglutination titer. The ... Read more >>

Int J Clin Exp Med (International journal of clinical and experimental medicine)
[2014, 7(6):1592-1597]

Cited: 11 times

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Lack of Any Role of Systemic Inflammatory Responses in Predicting Muscle Invasion by Bladder Cancer.

Mehmet Solakhan, Ozlem Demirpence, Nuri Orhan, Omer Aydin Yildirim, Ebru Guzel, Mustafa Yildirim,

<h4>Background</h4>The purpose of this study is to evaluate if there is a relation between platelet:lymphocyte ratio (PLR) and neutrophil lymphocyte ratio (NLR) values and tumour histology and spread in bladder cancer cases.<h4>Materials and methods</h4>Bladder cancer patients undergoing TUR-M operation, with histopathologically verified diagnosis, followed-up and treated at the Private Medical ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2016, 17(8):3737-3739]

Cited: 0 times

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Expression pattern and prognostic significance of claudin 1, 4 and 7 in pancreatic cancer.

Arsenal Sezgin Alikanoglu, Seyda Gunduz, Ozlem Demirpence, Dinc Suren, Umut Riza Gunduz, Cem Sezer, Mustafa Yildiz, Mustafa Yildirim,

<h4>Background</h4>Tight junctions (TJs) organise paracellular permeability and they have an important role in epithelial and endothelial cell polarity and permanence of barrier function. It has been demonstrated that the Claudin family constitutes an important component of them. In this study, we assessed expression patterns of of Claudin1, 4 and 7 ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2015, 16(10):4387-4392]

Cited: 6 times

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Prognostic significance of p53 in gastric cancer: a meta- analysis.

Mustafa Yildirim, Vildan Kaya, Ozlem Demirpence, Seyda Gunduz, Hakan Bozcuk,

<h4>Background</h4>Gastric cancer is one of the frequently seen cancers in the world and it is the second most common reason for death due to cancer. The prognostic role of expression of p53 detected by immunohistochemistry in gastric cancer remains controversial. This meta-analysis aimed to explore any association between overexpression and ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2015, 16(1):327-332]

Cited: 19 times

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A multicenter nationwide reference intervals study for common biochemical analytes in Turkey using Abbott analyzers.

Yesim Ozarda, Kiyoshi Ichihara, Diler Aslan, Hulya Aybek, Zeki Ari, Fatma Taneli, Canan Coker, Pinar Akan, Ali Riza Sisman, Onur Bahceci, Nurzen Sezgin, Meltem Demir, Gultekin Yucel, Halide Akbas, Sebahat Ozdem, Gurbuz Polat, Ayse Binnur Erbagci, Mustafa Orkmez, Nuriye Mete, Osman Evliyaoglu, Aysel Kiyici, Husamettin Vatansev, Bahadir Ozturk, Dogan Yucel, Damla Kayaalp, Kubra Dogan, Asli Pinar, Mehmet Gurbilek, Cigdem Damla Cetinkaya, Okhan Akin, Muhittin Serdar, Ismail Kurt, Selda Erdinc, Ozgur Kadicesme, Necip Ilhan, Dilek Sadak Atali, Ebubekir Bakan, Harun Polat, Tevfik Noyan, Murat Can, Abdulkerim Bedir, Ali Okuyucu, Orhan Deger, Suret Agac, Evin Ademoglu, Ayşem Kaya, Turkan Nogay, Nezaket Eren, Melahat Dirican, GulOzlem Tuncer, Mehmet Aykus, Yeliz Gunes, Sevda Unalli Ozmen, Reo Kawano, Sehavet Tezcan, Ozlem Demirpence, Elif Degirmen,

<h4>Background</h4>A nationwide multicenter study was organized to establish reference intervals (RIs) in the Turkish population for 25 commonly tested biochemical analytes and to explore sources of variation in reference values, including regionality.<h4>Methods</h4>Blood samples were collected nationwide in 28 laboratories from the seven regions (≥400 samples/region, 3066 in all). The sera ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2014, 52(12):1823-1833]

Cited: 15 times

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Non-Hodgkin lymphoma and pesticide exposure in Turkey.

Mustafa Yildirim, Hulya Karakilinc, Mustafa Yildiz, Erdal Kurtoglu, Utku Donem Dilli, Sevil Goktas, Ozlem Demirpence, Vildan Kaya,

<h4>Background</h4>Non-Hodgkin lymphoma (NHL) is a solid tumour of lymphocytes, important elements in the immune system. According to 2006 data, in Turkey the incidence was 6.5 per 100,000 in males, and 4.4 in females. The relationship between the use of pesticides and development of NHL has been extensively investigated in many ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2013, 14(6):3461-3463]

Cited: 0 times

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Roles for paraoxonase but not ceruloplasmin in peritoneal washing fluid in differential diagnosis of gynecologic pathologies.

Mustafa Yildirim, Ozlem Demirpence, Vildan Kaya, Dinc Suren, Mehmet Karaca, Osman Evliyaoglu, Necat Yilmaz, Seyda Gunduz,

<h4>Background</h4>Intraperitoneal spread of gynecologic cancers is a major cause of mortality and morbidity and often presents with malignant ascites. Microscopic tumor spread can be demonstrated by a peritoneal wash cytology and help assess the prognosis of the disease. In our study, the roles of paraoxonase and ceruloplasmin, measured in peritoneal ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2014, 15(15):6233-6237]

Cited: 0 times

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Esophageal cancer, gastric cancer and the use of pesticides in the southwestern of Turkey.

Mustafa Yildirim, Vildan Kaya, Mustafa Yildiz, Ozlem Demirpence, Seyda Gunduz, Utku Donem Dilli,

<h4>Background</h4>Esophageal and gastric cancer generally have a poor prognosis and may share common risk factors. It has been demonstrated that the pesticide usage may contribute to development of many cancer types. In this study, the relation between amount of pesticides used in agriculture and esophageal and gastric cancer incidence was ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2014, 15(6):2821-2823]

Cited: 2 times

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Prognostic significance of basic laboratory methods in non- small-cell-lung cancer.

Vildan Kaya, Mustafa Yildirim, Ozlem Demirpence, Mustafa Yildiz, Aysen Yesim Yalcin,

<h4>Background</h4>In our study, the LDH, albumin, hemoglobin, neutrophile, thrombocyte, lymphocyte counts and prognostic significance of neutrophile-lymphocyte and thrombocyte-lymphocyte ratios in NSCLC derived from these counts obtained during regular examinations of patients were examined.<h4>Materials and methods</h4>Histopathologically diagnosed non-small-cell-lung cancer patients between 2008 and 2010 were included in the study. Before the ... Read more >>

Asian Pac J Cancer Prev (Asian Pacific journal of cancer prevention : APJCP)
[2013, 14(9):5473-5476]

Cited: 12 times

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