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Author On Kyun Kang

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Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus in Korea: High Rate of False Resistance to Linezolid by the VITEK 2 System.

In Young Yoo, On Kyun Kang, Hyang Jin Shim, Hee Jae Huh, Nam Yong Lee,

As various linezolid resistance mechanisms have been identified in methicillin-resistant Staphylococcus aureus (MRSA), we investigated the molecular characteristics of MRSA with elevated linezolid minimum inhibitory concentrations (MICs), using the VITEK 2 system (bioMérieux, Marcy-l'Étoile, France). Twenty-seven MRSA isolates from 14 patients exhibiting linezolid MICs ≥8 μg/mL were examined by broth ... Read more >>

Ann Lab Med (Annals of laboratory medicine)
[2020, 40(1):57-62]

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First Case of Bacteremia Caused by Coprobacillus catenaformis.

Won Young Heo, Jong Kwon Lee, Yoo Na Chung, In Young Yoo, On-Kyun Kang, Duk Hyun Sung, Sun Young Cho, Hee Jae Huh, Nam Yong Lee,

Ann Lab Med (Annals of laboratory medicine)
[2020, 40(5):421-423]

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Comparison of 16S Ribosomal RNA Targeted Sequencing and Culture for Bacterial Identification in Normally Sterile Body Fluid Samples: Report of a 10-Year Clinical Laboratory Review.

In Young Yoo, On Kyun Kang, Myoung Keun Lee, Yae Jean Kim, Sun Young Cho, Kyungmin Huh, Cheol In Kang, Doo Ryeon Chung, Kyong Ran Peck, Hee Jae Huh, Nam Yong Lee,

As 16S ribosomal RNA (rRNA)-targeted sequencing can detect DNA from non-viable bacteria, it can be used to identify pathogens from clinical samples even in patients pretreated with antibiotics. We compared the results of 16S rRNA-targeted sequencing and culture for identifying bacterial species in normally sterile body fluid (NSBF): cerebrospinal, pericardial, ... Read more >>

Ann Lab Med (Annals of laboratory medicine)
[2020, 40(1):63-67]

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Evaluation of the BioFire FilmArray Pneumonia Panel for rapid detection of respiratory bacterial pathogens and antibiotic resistance genes in sputum and endotracheal aspirate specimens.

In Young Yoo, Kyungmin Huh, Hyang Jin Shim, Sun Ae Yun, Yoo Na Chung, On Kyun Kang, Hee Jae Huh, Nam Yong Lee,

OBJECTIVES:The performance of the investigational-use-only version of the BioFire FilmArray Pneumonia Panel (FA-Pneumo), a high-order nested multiplex PCR, was evaluated for the detection of typical respiratory bacterial pathogens and antibiotic resistance genes in sputa and endotracheal aspirate (ETA) specimens. METHODS:Thirty-one sputa and 69 ETA specimens were analyzed. The diagnostic performance ... Read more >>

Int. J. Infect. Dis. (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2020, 95:326-331]

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Diagnostic Performance of the GENEDIA MTB/NTM Detection Kit for Detecting Mycobacterium tuberculosis and Nontuberculous Mycobacteria With Sputum Specimens.

Sunghwan Shin, In Young Yoo, Hyang Jin Shim, On Kyun Kang, Byung Woo Jhun, Won Jung Koh, Hee Jae Huh, Nam Yong Lee,

The GENEDIA MTB/NTM Detection Kit (GENEDIA MTB/NTM; Green Cross Medical Science Corp., Chungbuk, Korea) is a multiplex real-time PCR assay used for differential identification of Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacteria (NTM). While the importance of differential identification of MTB/NTM is recognized, there is limited data on the performance ... Read more >>

Ann Lab Med (Annals of laboratory medicine)
[2020, 40(2):169-173]

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GenoType NTM-DR Performance Evaluation for Identification of Mycobacterium avium Complex and Mycobacterium abscessus and Determination of Clarithromycin and Amikacin Resistance.

Hee Jae Huh, Su-Young Kim, Hyang Jin Shim, Dae Hun Kim, In Young Yoo, On-Kyun Kang, Chang-Seok Ki, So Youn Shin, Byung Woo Jhun, Sung Jae Shin, Charles L Daley, Won-Jung Koh, Nam Yong Lee,

We evaluated the GenoType NTM-DR (NTM-DR) line probe assay for identifying Mycobacterium avium complex (MAC) species and Mycobacterium abscessus subspecies and for determining clarithromycin and amikacin resistance. Thirty-eight reference strains and 145 clinical isolates (58 MAC and 87 M. abscessus isolates), including 54 clarithromycin- and/or amikacin-resistant strains, were involved. The ... Read more >>

J. Clin. Microbiol. (Journal of clinical microbiology)
[2019, 57(8):]

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Advantages of the AdvanSure MDR-TB GenoBlot assay containing disputed rpoB mutation-specific probes in a routine clinical laboratory setting.

In Young Yoo, Hee Jae Huh, On-Kyun Kang, Byung Woo Jhun, Won-Jung Koh, Nam Yong Lee,

BACKGROUND:The AdvanSure MDR-TB GenoBlot Assay detects isoniazid- and rifampin-resistant tuberculosis using mutation-specific probes, including probes to disputed rpoB mutations. The aim of this study was to evaluate the clinical usefulness of molecular drug susceptibility testing (DST) using the AdvanSure assay with weekly batch testing in routine clinical laboratory settings in ... Read more >>

Respir Med (Respiratory medicine)
[2019, 146:71-75]

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