Full Text Journal Articles by
Author Olga O Bochkareva

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Chlamydia pan-genomic analysis reveals balance between host adaptation and selective pressure to genome reduction.

Olga M Sigalova, Andrei V Chaplin, Olga O Bochkareva, Pavel V Shelyakin, Vsevolod A Filaretov, Evgeny E Akkuratov, Valentina Burskaia, Mikhail S Gelfand,

BACKGROUND:Chlamydia are ancient intracellular pathogens with reduced, though strikingly conserved genome. Despite their parasitic lifestyle and isolated intracellular environment, these bacteria managed to avoid accumulation of deleterious mutations leading to subsequent genome degradation characteristic for many parasitic bacteria. RESULTS:We report pan-genomic analysis of sixteen species from genus Chlamydia including identification ... Read more >>

BMC Genomics (BMC genomics)
[2019, 20(1):710]

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Micro-evolution of three Streptococcus species: selection, antigenic variation, and horizontal gene inflow.

Pavel V Shelyakin, Olga O Bochkareva, Anna A Karan, Mikhail S Gelfand,

BACKGROUND:The genus Streptococcus comprises pathogens that strongly influence the health of humans and animals. Genome sequencing of multiple Streptococcus strains demonstrated high variability in gene content and order even in closely related strains of the same species and created a newly emerged object for genomic analysis, the pan-genome. Here we ... Read more >>

BMC Evol. Biol. (BMC evolutionary biology)
[2019, 19(1):83]

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Genome rearrangements and selection in multi-chromosome bacteria Burkholderia spp.

Olga O Bochkareva, Elena V Moroz, Iakov I Davydov, Mikhail S Gelfand,

BACKGROUND:The genus Burkholderia consists of species that occupy remarkably diverse ecological niches. Its best known members are important pathogens, B. mallei and B. pseudomallei, which cause glanders and melioidosis, respectively. Burkholderia genomes are unusual due to their multichromosomal organization, generally comprised of 2-3 chromosomes. RESULTS:We performed integrated genomic analysis of ... Read more >>

BMC Genomics (BMC genomics)
[2018, 19(1):965]

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Genome rearrangements and phylogeny reconstruction in Yersinia pestis.

Olga O Bochkareva, Natalia O Dranenko, Elena S Ocheredko, German M Kanevsky, Yaroslav N Lozinsky, Vera A Khalaycheva, Irena I Artamonova, Mikhail S Gelfand,

Genome rearrangements have played an important role in the evolution of Yersinia pestis from its progenitor Yersinia pseudotuberculosis. Traditional phylogenetic trees for Y. pestis based on sequence comparison have short internal branches and low bootstrap supports as only a small number of nucleotide substitutions have occurred. On the other hand, ... Read more >>

PeerJ (PeerJ)
[2018, 6:e4545]

Cited: 1 time

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