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Author O Morel

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[Training in fetal ultrasound biometry: prospective assesment of Objective Structured Assessment of Ultrasound Skills (OSAUS) efficiency.]

G Ambroise Grandjean, P Gabriel, G Hossu, S Zuily, O Morel, P Berveiller,

BACKGROUND:Fetal biometry quality directly influences obstetrical care relevance. However, obstetrician proficiencies are heterogeneous in particular during initial training. OBJECTIVES:to assess the predictive value of OSAUS scale to identify operators with enough command to perform a valid estimation of fetal weight (EFW) (I). This study also assesses OSAUS intra-operator inter-exams variability ... Read more >>

Gynecol Obstet Fertil Senol (Gynecologie, obstetrique, fertilite & senologie)
[2020, :]

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Experiences of fathers having faced with termination of pregnancy for foetal abnormality.

Kahina Aliouat Kecir, Sophie Rothenburger, Olivier Morel, Eliane Albuisson, Fabienne Ligier,

The development of medical ultrasound techniques and progress in prenatal diagnosis allows foetus malformations to be discovered during pregnancy. These outcomes may force parents to be faced with the decision of termination of pregnancy for foetal abnormality (TOP). According to the literature, some parents will develop somatic or psychological troubles ... Read more >>

J Gynecol Obstet Hum Reprod (Journal of gynecology obstetrics and human reproduction)
[2020, :101818]

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Relationship between stent expansion and post-PCI fractional flow reserve: a DOCTORS sub study.

Salim Belguidoum, Nicolas Meneveau, Pascal Motreff, Patrick Ohlman, Mehdi Boussaada, Johanne Silvain, Benoit Guillon, Vincent Descotes-Genon, Yohann Lefrançois, Olivier Morel, Nicolas Amabile,

AIMS:To analyse the relationship between stent expansion criteria using optical coherence tomography (OCT) analysis and the final PCI functional result. METHODS AND RESULTS:This post-hoc analysis of the DOCTORS study included non-ST elevation segment ACS patients undergoing OCT-guided PCI. The procedure functional result was assessed by the measurement of fractional flow ... Read more >>

EuroIntervention (EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology)
[2020, :]

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Impact of COVID-19 on the Cardiovascular System: A Review.

Kensuke Matsushita, Benjamin Marchandot, Laurence Jesel, Patrick Ohlmann, Olivier Morel,

The recent outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has been declared a public health emergency of international concern. COVID-19 may present as acute respiratory distress syndrome in severe cases, and patients with pre-existing cardiovascular comorbidities are reported to be the most vulnerable. ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(5):]

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Inappropriate shock due to quadruple counting in a patient with subcutaneous implantable cardioverter-defibrillator and a dual-chamber pacemaker.

Halim Marzak, Olivier Morel, Laurence Jesel,

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2020, :]

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[INFECTIVE ENDOCARDITIS DURING PREGNANCY].

Rémi Pillot, Émilie Gauchotte, Olivier Morel, Matthieu Chamagne,

Gynecol Obstet Fertil Senol (Gynecologie, obstetrique, fertilite & senologie)
[2020, :]

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Prospective assessment of reproducibility of three-dimensional ultrasound for fetal biometry.

G Ambroise Grandjean, P Berveiller, G Hossu, P Noble, M Chamagne, O Morel,

To compare fetal ultrasound measurements performed by two observers with different levels of experience and evaluate the potential contribution of the use of three-dimensional (3D) ultrasound on repeatability, reproducibility and agreement of two-dimensional (2D) and 3D-derived measurements. Two observers (one senior and one junior) measured head circumference (HC), abdominal circumference ... Read more >>

Diagn Interv Imaging (Diagnostic and interventional imaging)
[2020, :]

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Bedside Renal Doppler Ultrasonography and Acute Kidney Injury after TAVR.

Marilou Peillex, Benjamin Marchandot, Sophie Bayer, Eric Prinz, Kensuke Matsushita, Adrien Carmona, Joe Heger, Antonin Trimaille, Hélène Petit-Eisenmann, Laurence Jesel, Patrick Ohlmann, Olivier Morel,

Acute kidney injury (AKI) following transcatheter aortic valve replacement (TAVR) is associated with a dismal prognosis. Elevated renal resistive index (RRI), through renal Doppler ultrasound (RDU) evaluation, has been associated with AKI development and increased systemic arterial stiffness. Our pilot study aimed to investigate the performance of Doppler based RRI ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(4):]

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Systemic Inflammatory Response Syndrome Is a Major Determinant of Cardiovascular Outcome in Takotsubo Syndrome.

Lucie Lachmet-Thébaud, Benjamin Marchandot, Kensuke Matsushita, Charlotte Dagrenat, Marilou Peillex, Chisato Sato, Antonin Trimaille, Antje Reydel, Annie Trinh, Patrick Ohlmann, Laurence Jesel, Olivier Morel,

BACKGROUND:Recent insights have emphasized the importance of inflammatory response in takotsubo syndrome (TTS). We sought to evaluate the predictors of systemic inflammatory response syndrome (SIRS) and its impact on cardiovascular mortality after TTS.Methods and Results:The 215 TTS patients were retrospectively included between September 2008 and January 2018. SIRS was diagnosed in 96 ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, 84(4):592-600]

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[Cystic fibrosis and pregnancy: Outcome, prognostic factors and obstetrical management].

A-L Fijean, M Chamagne, Y Billon, O Morel, S Dahlhoff,

As a result of improvements in life expectancy and therapies, increasing numbers of patients with cystic fibrosis become pregnant. The first studies were pessimistic and report adverse outcomes on the fetus and the mother. In the recent publications, long-term outcome for women with cystic fibrosis does not appear to be ... Read more >>

Gynecol Obstet Fertil Senol (Gynecologie, obstetrique, fertilite & senologie)
[2020, 48(5):428-435]

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[Intrauterine tamponade: Practices and training assessment].

L Pouypoudat, L Tomczyk, E Gauchotte, O Morel, C Bertholdt,

OBJECTIVES:The main objective was to describe the practices of a French center regarding the use of intrauterine tamponade. The secondary objective was to describe the training of residents in the use of intrauterine tamponade (IUT). METHODS:This was a practice survey conducted through an anonymous quiz sent to residents in France ... Read more >>

Gynecol Obstet Fertil Senol (Gynecologie, obstetrique, fertilite & senologie)
[2020, 48(5):409-413]

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Empagliflozin improved systolic blood pressure, endothelial dysfunction and heart remodeling in the metabolic syndrome ZSF1 rat.

Sin-Hee Park, Muhammad Akmal Farooq, Sébastien Gaertner, Christophe Bruckert, Abdul Wahid Qureshi, Hyun-Ho Lee, Djamel Benrahla, Brigitte Pollet, Dominique Stephan, Patrick Ohlmann, Jean-Marc Lessinger, Eric Mayoux, Cyril Auger, Olivier Morel, Valérie B Schini-Kerth,

BACKGROUND:Empagliflozin (empa), a selective sodium-glucose cotransporter (SGLT)2 inhibitor, reduced cardiovascular mortality and hospitalization for heart failure in patients with type 2 diabetes at high cardiovascular risk independent of glycemic control. The cardiovascular protective effect of empa was evaluated in an experimental model of metabolic syndrome, the obese ZSF1 rat, and ... Read more >>

Cardiovasc Diabetol (Cardiovascular diabetology)
[2020, 19(1):19]

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The difficult balance between thrombosis and bleeding after transcatheter aortic valve replacement: A translational review.

Antonin Trimaille, Benjamin Marchandot, Sin-Hee Park, Valérie Schini-Kerth, Olivier Morel,

Transcatheter aortic valve replacement (TAVR) has emerged as the treatment of choice for patients with severe aortic stenosis deemed at high or intermediate risk for cardiac surgery. In light of the latest literature advances, TAVR will undoubtedly concern a growing number of patients because of the progressive extension of its ... Read more >>

Arch Cardiovasc Dis (Archives of cardiovascular diseases)
[2020, 113(4):263-275]

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Hypermetabolism of the spleen or bone marrow is an additional albeit indirect sign of infective endocarditis at FDG-PET.

Caroline Boursier, Xavier Duval, Besma Mahida, Bruno Hoen, François Goehringer, Christine Selton-Suty, Elodie Chevalier, Véronique Roch, Zohra Lamiral, Aurélie Bourdon, Nicolas Piriou, Amandine Pallardy, Olivier Morel, François Rouzet, Pierre-Yves Marie, ,

PURPOSE:This study aimed at determining the diagnostic implications of indirect signs of infection at FDG-PET-i.e., hypermetabolisms of the spleen and/or bone marrow (HSBM)-when documented in patients with known or suspected infective endocarditis (IE). METHODS:HSBM were defined by higher mean standardized uptake values comparatively to that of the liver on FDG-PET ... Read more >>

J Nucl Cardiol (Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology)
[2020, :]

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TRAAP2 - TRAnexamic Acid for Preventing postpartum hemorrhage after cesarean delivery: a multicenter randomized, doubleblind, placebo- controlled trial - a study protocol.

Loïc Sentilhes, Valérie Daniel, Catherine Deneux-Tharaux, ,

BACKGROUND:An antifibrinolytic agent that blocks lysine-binding sites on plasminogen molecules, tranexamic acid reduces bleeding-related mortality in women with postpartum hemorrhage (PPH), especially administered fairly soon after delivery. According to the randomized controlled trials thus far reported for PPH prevention after cesarean deliveries (n = 16), women who received tranexamic acid had significantly ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2020, 20(1):63]

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Atrial Fibrillation Progression Is Associated with Cell Senescence Burden as Determined by p53 and p16 Expression.

Laurence Jesel, Malak Abbas, Sin-Hee Park, Kensuke Matsushita, Michel Kindo, Hira Hasan, Cyril Auger, Chisato Sato, Patrick Ohlmann, Jean-Philippe Mazzucotelli, Florence Toti, Gilles Kauffenstein, Valérie Schini-Kerth, Olivier Morel,

BACKGROUND:Whilst the link between aging and thrombogenicity in atrial fibrillation (AF) is well established, the cellular underlying mechanisms are unknown. In AF, the role of senescence in tissue remodeling and prothrombotic state remains unclear. AIMS:We investigated the link between AF and senescence by comparing the expression of senescence markers (p53 ... Read more >>

J Clin Med (Journal of clinical medicine)
[2019, 9(1):]

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Optimization of Fetal Biometry With 3D Ultrasound and Image Recognition (EPICEA): protocol for a prospective cross-sectional study.

Gaëlle Ambroise Grandjean, Gabriela Hossu, Claire Banasiak, Cybele Ciofolo-Veit, Caroline Raynaud, Laurence Rouet, Olivier Morel, Marine Beaumont,

CONTEXT:Variability in 2D ultrasound (US) is related to the acquisition of planes of reference and the positioning of callipers and could be reduced in combining US volume acquisitions and anatomical structures recognition. OBJECTIVES:The primary objective is to assess the consistency between 3D measurements (automated and manual) extracted from a fetal ... Read more >>

BMJ Open (BMJ open)
[2019, 9(12):e031777]

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Percutaneous repair or medical treatment for secondary mitral regurgitation: outcomes at 2 years.

Bernard Iung, Xavier Armoiry, Alec Vahanian, Florent Boutitie, Nathan Mewton, Jean-Noël Trochu, Thierry Lefèvre, David Messika-Zeitoun, Patrice Guerin, Bertrand Cormier, Eric Brochet, Hélène Thibault, Dominique Himbert, Sophie Thivolet, Guillaume Leurent, Guillaume Bonnet, Erwan Donal, Nicolas Piriou, Christophe Piot, Gilbert Habib, Frédéric Rouleau, Didier Carrié, Mohammed Nejjari, Patrick Ohlmann, Christophe Saint Etienne, Lionel Leroux, Martine Gilard, Géraldine Samson, Gilles Rioufol, Delphine Maucort-Boulch, Jean François Obadia, ,

AIMS:The MITRA-FR trial showed that among symptomatic patients with severe secondary mitral regurgitation, percutaneous repair did not reduce the risk of death or hospitalization for heart failure at 12 months compared with guideline-directed medical treatment alone. We report the 24-month outcome from this trial. METHODS AND RESULTS:At 37 centres, we randomly ... Read more >>

Eur. J. Heart Fail. (European journal of heart failure)
[2019, 21(12):1619-1627]

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[Postnatal outcome from polyhydramnios without sonographic abnormalities].

C Bertholdt, A-L Fijean, O Morel, C Zuily-Lamy,

OBJECTIVES:To assess adverse outcome of polyhydramnios without morphological abnormalities and to determine the factors associated with an adverse outcome. METHODS:This is a retrospective observational cohort study conducted in a French tertiary care unit between 2008 and 2018 including all women with singleton pregnancy complicated by polyhydramnios. Presence of morphological abnormality ... Read more >>

Gynecol Obstet Fertil Senol (Gynecologie, obstetrique, fertilite & senologie)
[2020, 48(2):162-166]

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P2Y12 Inhibition by Clopidogrel Increases Periprocedural Bleeds in Patients Undergoing Transcatheter Aortic Valve Replacement.

Kensuke Matsushita, Benjamin Marchandot, Marion Kibler, Antonin Trimaille, Sebastien Hess, Lelia Grunebaum, Antje Reydel, Laurence Jesel, Patrick Ohlmann, Olivier Morel,

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, 74(21):2707-2708]

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Effect of the addition of osmotic dilators to medical induction of labor abortion: A before-and-after study.

Charline Bertholdt, Manuel Gomes David, Priscillia Gabriel, Olivier Morel, E Perdriolle-Galet,

OBJECTIVES:The main objective of this study was to assess the induction-to-delivery interval with or without the use of osmotic dilators for induced abortion. As secondary objectives, women outcomes were assessed. STUDY DESIGN:This retrospective single-center observational before and after study reviewed records from a university hospital maternity unit from 2002 through ... Read more >>

Eur. J. Obstet. Gynecol. Reprod. Biol. (European journal of obstetrics, gynecology, and reproductive biology)
[2020, 244:185-189]

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Progression of left anterior descending artery dissection due to stent implantation for spontaneous coronary artery dissection of left circumflex artery: a case report.

Kensuke Matsushita, Jessica Ristorto, Olivier Morel, Patrick Ohlmann,

Background:Spontaneous coronary artery dissection (SCAD) is a rare disease that predominantly affects woman. Percutaneous coronary intervention (PCI) is recommended only in patients with ongoing ischaemia because it carries a high risk of procedural complications in SCAD patients. Case summary:A 51-year-old woman was admitted to our institution owing to severe chest ... Read more >>

Eur Heart J Case Rep (European Heart Journal: Case Reports)
[2019, 3(4):1-6]

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Acute Cardiac Failure Due to Takotsubo Cardiomyopathy Secondary to a Phone Call for Lung Transplantation: A Case Report.

L Kassegne, T Degot, O Morel, J Reeb, A Carmona, A Schuller, S Hirschi, M Porzio, G Martin, M Riou, R Kessler, B Renaud-Picard,

Lung transplantation is a therapeutic option for certain end-stage lung diseases. The phone call for lung transplantation is a major event in the life of these patients; as a result, it can generate significant stress. We herein present the case of a 58-year-old female patient with end-stage chronic obstructive pulmonary ... Read more >>

Transplant. Proc. (Transplantation proceedings)
[2019, 51(9):3167-3170]

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[Common femoral artery bailout stenting with covered stent graft due to TAVR vascular complication: Clinical long term follow-up].

E Drouelle, F De Poli, P Couppie, S Uhry, H Heyer, O Morel, P Ohlmann, S Hess, M Kibler, P Leddet,

BACKGROUND:Vascular complications are frequent in the context of transcatheter aortic valve replacement and may require the implantation of a covered stent graft in the common femforal artery. However, common femoral artery is considered to be at high risk of stent fracture or occlusion due to high mobility of the hip ... Read more >>

Ann Cardiol Angeiol (Paris) (Annales de cardiologie et d'angeiologie)
[2019, 68(5):316-324]

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Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns.

Hira Hasan, Sin-Hee Park, Cyril Auger, Eugenia Belcastro, Kensuke Matsushita, Benjamin Marchandot, Hyun-Ho Lee, Abdul Wahid Qureshi, Gilles Kauffenstein, Patrick Ohlmann, Valérie B Schini-Kerth, Laurence Jesel, Olivier Morel,

BACKGROUND:Besides its well-known functions in hemostasis, thrombin plays a role in various non-hemostatic biological and pathophysiologic processes. We examined the potential of thrombin to promote premature atrial endothelial cells (ECs) senescence. METHODS AND RESULTS:Primary ECs were isolated from porcine atrial tissue. Endothelial senescence was assessed by measuring beta-galactosidase (SA-β-gal) activity ... Read more >>

J Clin Med (Journal of clinical medicine)
[2019, 8(10):]

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