Full Text Journal Articles by
Author Nuttada Panpradist

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Urine Biomarker Assessment of Infant Adherence to Isoniazid Prophylaxis.

Sylvia M LaCourse, Daniel Leon, Nuttada Panpradist, Barbra A Richardson, Elizabeth Maleche-Obimbo, Jerphason Mecha, Daniel Matemo, Jaclyn N Escudero, John Kinuthia, Barry Lutz, Grace John-Stewart,

We assessed adherence in an infant tuberculosis prevention trial in Kenya with a urine isoniazid metabolite-detecting dipstick. Ninety-seven infants had 155 assays performed; 77 (49.7%) were found to be positive despite caregiver-reported adherence. Positive assays were associated with maternal secondary education, HIV suppression and no reported missed doses in past ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(1):e43-e45]

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Near point-of-care, point-mutation test to detect drug resistance in HIV-1: a validation study in a Mexican cohort.

Nuttada Panpradist, Ingrid A Beck, Parker S Ruth, Santiago Ávila-Ríos, Claudia García-Morales, Maribel Soto-Nava, Daniela Tapia-Trejo, Margarita Matías-Florentino, Hector E Paz-Juarez, Silvia Del Arenal-Sanchez, Gustavo Reyes-Terán, Barry R Lutz, Lisa M Frenkel,

OBJECTIVE:Pretreatment HIV-drug resistance (PDR, HIVDR) to non-nucleoside reverse transcriptase inhibitors (NNRTIs) is increasing globally. NNRTIs continue to be used as first-line antiretroviral therapy (ART) in some communities due to the cost of dolutegravir-based ART or dolutegravir-associated adverse events. A simplified version of the oligonucleotide ligation assay (OLA) - 'OLA-Simple' - ... Read more >>

AIDS (AIDS (London, England))
[2020, 34(9):1331-1338]

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The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection

Zhiyuan Yao, Fabio Zanini, Sathish Kumar, Nuttada Panpradist, Avery Muniz, Stephen Quake, Shirit Einav,

Venezuelan Equine Encephalitis Virus (VEEV) is a major biothreat agent that naturally causes outbreaks in humans and horses particularly in tropical areas of the western hemisphere, for which no antiviral therapy is currently available. The host response to VEEV and the cellular factors this alphavirus hijacks to support its effective ... Read more >>

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OLA-Simple: A software-guided HIV-1 drug resistance test for low-resource laboratories.

Nuttada Panpradist, Ingrid A Beck, Justin Vrana, Nikki Higa, David McIntyre, Parker S Ruth, Isaac So, Enos C Kline, Ruth Kanthula, Annie Wong-On-Wing, Jonathan Lim, Daisy Ko, Ross Milne, Theresa Rossouw, Ute D Feucht, Michael Chung, Gonzague Jourdain, Nicole Ngo-Giang-Huong, Laddawan Laomanit, Jaime Soria, James Lai, Eric D Klavins, Lisa M Frenkel, Barry R Lutz,

<h4>Background</h4>HIV drug resistance (HIVDR) testing can assist clinicians in selecting treatments. However, high complexity and cost of genotyping assays limit routine testing in settings where HIVDR prevalence has reached high levels.<h4>Methods</h4>The oligonucleotide ligation assay (OLA)-Simple kit was developed for detection of HIVDR against first-line non-nucleoside/nucleoside reverse transcriptase inhibitors and validated ... Read more >>

EBioMedicine (EBioMedicine)
[2019, 50:34-44]

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Analytical Comparison of Methods for Extraction of Short Cell-Free DNA from Urine.

Amy Oreskovic, Norman D Brault, Nuttada Panpradist, James J Lai, Barry R Lutz,

Urine cell-free DNA (cfDNA) is a valuable noninvasive biomarker for cancer mutation detection, infectious disease diagnosis (eg, tuberculosis), organ transplantation monitoring, and prenatal screening. Conventional silica DNA extraction does not efficiently capture urine cfDNA, which is dilute (ng/mL) and highly fragmented [30 to 100 nucleotides (nt)]. The clinical sensitivity of ... Read more >>

J Mol Diagn (The Journal of molecular diagnostics : JMD)
[2019, 21(6):1067-1078]

Cited: 2 times

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Simplified Paper Format for Detecting HIV Drug Resistance in Clinical Specimens by Oligonucleotide Ligation.

Nuttada Panpradist, Ingrid A Beck, Michael H Chung, James N Kiarie, Lisa M Frenkel, Barry R Lutz,

Human immunodeficiency virus (HIV) is a chronic infection that can be managed by antiretroviral treatment (ART). However, periods of suboptimal viral suppression during lifelong ART can select for HIV drug resistant (DR) variants. Transmission of drug resistant virus can lessen or abrogate ART efficacy. Therefore, testing of individuals for drug ... Read more >>

PLoS One (PloS one)
[2016, 11(1):e0145962]

Cited: 8 times

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Swab sample transfer for point-of-care diagnostics: characterization of swab types and manual agitation methods.

Nuttada Panpradist, Bhushan J Toley, Xiaohong Zhang, Samantha Byrnes, Joshua R Buser, Janet A Englund, Barry R Lutz,

<h4>Background</h4>The global need for disease detection and control has increased effort to engineer point-of-care (POC) tests that are simple, robust, affordable, and non-instrumented. In many POC tests, sample collection involves swabbing the site (e.g., nose, skin), agitating the swab in a fluid to release the sample, and transferring the fluid ... Read more >>

PLoS One (PloS one)
[2014, 9(9):e105786]

Cited: 9 times

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