Full Text Journal Articles by
Author Nikita Lakomkin

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Too frail is to fail: Frailty portends poor outcomes in the elderly with type II odontoid fractures independent of management strategy.

Lucas P Carlstrom, Ahmed Helal, Avital Perry, Nikita Lakomkin, Christopher S Graffeo, Michelle J Clarke,

Type-II odontoid fractures are common and highly morbid injuries, particularly among elderly patients. However, few risk stratification resources exist to predict outcomes and guide management decision making. Frailty indices have been increasingly utilized for these purposes in elective surgery, but have not been assessed for trauma. A single-center prospective trauma ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2021, 93:48-53]

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Lower Hounsfield Units at the Upper Instrumented Vertebrae are Significantly Associated With Proximal Junctional Kyphosis and Failure Near the Thoracolumbar Junction.

Anthony L Mikula, Jeremy L Fogelson, Nikita Lakomkin, Patrick M Flanigan, Zachariah W Pinter, Matthew K Doan, Mohamad Bydon, Ahmad Nassr, Brett Freedman, Arjun S Sebastian, Kingsley Abode-Iyamah, Paul A Anderson, Benjamin D Elder,

<h4>Background</h4>Low bone mineral density (BMD) on dual energy x-ray absorptiometry (DXA) is likely a risk factor for proximal junctional kyphosis (PJK) and proximal junctional failure (PJF). However, prior instrumentation and degenerative changes can preclude a lumbar BMD measurement. Hounsfield units (HU) represent an alternative method to estimate BMD via targeted ... Read more >>

Oper Neurosurg (Hagerstown) (Operative neurosurgery (Hagerstown, Md.))
[2021, 21(4):270-275]

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Timing of referral to peripheral nerve specialists in patients with postoperative C5 palsy.

Zach Pennington, Daniel Lubelski, Nikita Lakomkin, Benjamin D Elder, Timothy F Witham, Sheng-Fu Larry Lo, Daniel M Sciubba,

The objective of this study was to examine the association between electrophysiology data post-C5-palsy and referral to peripheral nerve surgeons (PNS) using a 15-year cohort of patients who underwent posterior cervical decompression. Endpoints included the associations of postoperative treatments employed with functional recovery and abnormal electrophysiology data. Of 77 included ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2021, 92:169-174]

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A significant association between C5 nerve sheath tumors and new postoperative weakness.

Anthony L Mikula, Brandon W Smith, Nikita Lakomkin, Matthew K Doan, Megan M Jack, Mohamad Bydon, Robert J Spinner,

<h4>Objective</h4>The objective of this study was to determine if patients with nerve sheath tumors affecting the C5 spinal nerve are at greater risk for postoperative weakness than those with similar tumors affecting other spinal nerves contributing to the brachial plexus.<h4>Methods</h4>A retrospective chart review (1998-2020)identified patients with pathologically confirmed schwannomas or ... Read more >>

J Neurosurg Spine (Journal of neurosurgery. Spine)
[2021, :1-6]

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Comparison of surgical invasiveness and morbidity of adult spinal deformity surgery to other major operations.

Nikita Lakomkin, Blaine Stannard, Jeremy L Fogelson, Anthony L Mikula, Lawrence G Lenke, Scott L Zuckerman,

<h4>Background context</h4>Adult spinal deformity (ASD) surgeries are complex, involving long operative times and surgical morbidity. It is currently unclear how the invasiveness of ASD surgery compares to other major operations.<h4>Purpose</h4>To: (1) develop a quantitative score of surgical morbidity and invasiveness, and (2) compare this score between ASD surgery and other ... Read more >>

Spine J (The spine journal : official journal of the North American Spine Society)
[2021, 21(11):1784-1792]

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Is There a Difference in Screw Accuracy, Robot Time Per Screw, Robot Abandonment, and Radiation Exposure Between the Mazor X and the Renaissance? A Propensity-Matched Analysis of 1179 Robot-Assisted Screws.

Nathan J Lee, Scott L Zuckerman, Ian A Buchanan, Venkat Boddapati, Justin Mathew, Gerard Marciano, Djani Robertson, Nikita Lakomkin, Paul J Park, Eric Leung, Joseph M Lombardi, Ronald A Lehman,

<h4>Study design</h4>Prospective single-cohort analysis.<h4>Objectives</h4>To compare the outcomes/complications of 2 robotic systems for spine surgery.<h4>Methods</h4>Adult patients (≥18-years-old) who underwent robot-assisted spine surgery from 2016-2019 were assessed. A propensity score matching (PSM) algorithm was used to match Mazor X to Renaissance cases. Preoperative CT scan for planning and an intraoperative O-arm for ... Read more >>

Global Spine J (Global spine journal)
[2021, :21925682211029867]

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In Reply: The Role of Prophylactic Intraventricular Antibiotics in Reducing the Incidence of Infection and Revision Surgery in Pediatric Patients Undergoing Shunt Placement.

Nikita Lakomkin, Constantinos G Hadjipanayis,

Neurosurgery (Neurosurgery)
[2021, 89(1):E104]

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Fenestrated pedicle screws for thoracolumbar instrumentation in patients with poor bone quality: Case series and systematic review of the literature.

Jeff Ehresman, Zach Pennington, Aladine A Elsamadicy, Andrew Hersh, Daniel Lubelski, Kurt Lehner, Ethan Cottrill, Andrew Schilling, Nikita Lakomkin, A Karim Ahmed, Sheng-Fu Lo, Daniel M Sciubba,

<h4>Objective</h4>To describe the results of a single-surgeon series and systematically review the literature on cement-augmented instrumented fusion with fenestrated pedicle screws.<h4>Methods</h4>All patients treated by the senior surgeon using fenestrated screws between 2017 and 2019 with a minimum of 6-months of clinical and radiographic follow-up were included. For the systematic review, ... Read more >>

Clin Neurol Neurosurg (Clinical neurology and neurosurgery)
[2021, 206:106675]

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Predictors of Readmission and Prolonged Length of Stay After Cervical Disc Arthroplasty.

Michelle Zeidan, Vadim Goz, Nikita Lakomkin, Nicholas Spina, Darrel S Brodke, William R Spiker,

<h4>Study design</h4>Retrospective cohort study.<h4>Objective</h4>The aim of the study was to assess which factors increase risk of readmission within 30 days of surgery or prolonged length of stay (LOS) (≥2 days) after cervical disc arthroplasty (CDA).<h4>Summary of background data</h4>Several studies have shown noninferiority at mid- and long-term outcomes after cervical disc ... Read more >>

Spine (Phila Pa 1976) (Spine)
[2021, 46(8):487-491]

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Fluorescence-Guided High-Grade Glioma Surgery More Than Four Hours After 5-Aminolevulinic Acid Administration.

Georgios A Maragkos, Alexander J Schüpper, Nikita Lakomkin, Panagiotis Sideras, Gabrielle Price, Rebecca Baron, Travis Hamilton, Sameah Haider, Ian Y Lee, Constantinos G Hadjipanayis, Adam M Robin,

<b>Background:</b> Fluorescence-guided surgery (FGS) using 5-aminolevulic acid (5-ALA) is a widely used strategy for delineating tumor tissue from surrounding brain intraoperatively during high-grade glioma (HGG) resection. 5-ALA reaches peak plasma levels ~4 h after oral administration and is currently approved by the FDA for use 2-4 h prior to induction ... Read more >>

Front Neurol (Frontiers in neurology)
[2021, 12:644804]

Cited: 2 times

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Fluorescence guided surgery for pituitary adenomas.

Nikita Lakomkin, Jamie J Van Gompel, Kalmon D Post, Steve S Cho, John Y K Lee, Constantinos G Hadjipanayis,

<h4>Purpose</h4>Resection of pituitary adenomas presents a number of unique challenges in neuro-oncology. The proximity of these lesions to key vascular and endocrine structures as well as the need to interpret neuronavigation in the context of shifting tumor position increases the complexity of the operation. More recently, substantial advances in fluorescence-guided ... Read more >>

J Neurooncol (Journal of neuro-oncology)
[2021, 151(3):403-413]

Cited: 1 time

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The Role of Prophylactic Intraventricular Antibiotics in Reducing the Incidence of Infection and Revision Surgery in Pediatric Patients Undergoing Shunt Placement.

Nikita Lakomkin, Constantinos G Hadjipanayis,

<h4>Background</h4>Ventriculoperitoneal shunt placement remains the primary treatment modality for children with hydrocephalus. However, morbidity and revision surgery secondary to infection remains high, even while using antibiotic-impregnated shunts.<h4>Objective</h4>To determine whether intraoperative injection of antibiotics is independently associated with reduced rates of infection and revision surgery in children undergoing shunt placement.<h4>Methods</h4>This is ... Read more >>

Neurosurgery (Neurosurgery)
[2021, 88(2):301-305]

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Medical Student Publications in Neurosurgery: At Which U.S. Academic Institutions Do Medical Students Publish Most?

Gabrielle Price, Nikita Lakomkin, Samir Kamat, Rebecca B Baron, Lea Scherschinski, Constantinos Hadjipanayis,

<h4>Background</h4>The neurosurgery residency match is a competitive process. While medical research offers esteemed learning opportunities, productivity is closely evaluated by residency programs. Accordingly, students work diligently to make contributions on projects within their neurosurgery departments. The present study evaluated medical student research productivity for each of the 118 U.S. neurosurgery ... Read more >>

World Neurosurg (World neurosurgery)
[2021, 147:181-189.e1]

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Identifying the Most Appropriate ACDF Patients for an Ambulatory Surgery Center: A Pilot Study Using Inpatient and Outpatient Hospital Data.

Scott L Zuckerman, Nishit Mummareddy, Nikita Lakomkin, Ahilan Sivaganesan, Anthony Asher, Clinton J Devin,

<h4>Study design</h4>Retrospective cohort analysis of prospectively collected data.<h4>Objectives</h4>Using a national cohort of patients undergoing elective anterior cervical discectomy and fusion (ACDF) in an inpatient/outpatient setting, the current objectives were to: (1) outline preoperative factors that were associated with complications, and (2) describe potentially catastrophic complications so that this data can ... Read more >>

Clin Spine Surg (Clinical spine surgery)
[2020, 33(10):418-423]

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The Utility of Preoperative Labs in Predicting Postoperative Complications Following Primary Total Hip and Knee Arthroplasty.

Nikita Lakomkin, Claudette Lajam, Ginger E. Holt, Lorraine Hutzler, Richard Iorio, Joseph A. Bosco,

<h4>Background</h4>Preoperative testing costs billions of dollars despite little evidence supporting its utility. The purpose of this study was to determine the relationship between abnormal preoperative laboratory tests and postoperative complications following total joint arthroplasty.<h4>Methods</h4>The NSQIP database was used to identify 45,936 primary total hip arthroplasty (THA) and 76,041 pri-mary total ... Read more >>

Bull Hosp Jt Dis (2013) (Bulletin of the Hospital for Joint Disease (2013))
[2020, 78(4):266-274]

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Spinal cord injury in the United States Army Special Forces.

Remi A Kessler, Ansh Bhammar, Nikita Lakomkin, Raj K Shrivastava, Jonathan J Rasouli, Jeremy Steinberger, Joshua Bederson, Constantinos G Hadjipanayis, Deborah L Benzil,

<h4>Objective</h4>Spinal cord injury (SCI) is an area of key interest in military medicine but has not been studied among the US Army Special Forces (SF), the most elite group of US soldiers. SF soldiers make up a disproportionate 60% of all Special Operations casualties. The objective of this study was ... Read more >>

J Neurosurg Spine (Journal of neurosurgery. Spine)
[2020, :1-7]

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Postoperative outcomes following glioblastoma resection using a robot-assisted digital surgical exoscope: a case series.

Rebecca B Baron, Nikita Lakomkin, Alexander J Schupper, Dominic Nistal, Kambiz Nael, Gabrielle Price, Constantinos G Hadjipanayis,

<h4>Introduction</h4>Maximal extent of resection (EOR) of glioblastoma (GBM) is associated with greater progression free survival (PFS) and improved patient outcomes. Recently, a novel surgical system has been developed that includes a 2D, robotically-controlled exoscope and brain tractography display. The purpose of this study was to assess outcomes in a series ... Read more >>

J Neurooncol (Journal of neuro-oncology)
[2020, 148(3):519-527]

Cited: 2 times

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Shaping Our Understanding of Medulloblastoma: A Bibliometric Analysis of the 100 Most Cited Articles.

Victor M Lu, Courtney Pendleton, Desmond A Brown, Nikita Lakomkin, Steve Cho, Kai J Miller, David J Daniels,

The clinical management of medulloblastoma has undergone significant transformation since the recent dawn of the molecular era. The aim of this analysis was to evaluate citation and other bibliometric characteristics of the 100 most cited medulloblastoma articles in the literature to better understand the current state of our research efforts ... Read more >>

Clin Neurol Neurosurg (Clinical neurology and neurosurgery)
[2020, 194:105895]

Cited: 1 time

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Diffusion MRI Reversibility in Ischemic Stroke Following Thrombolysis: A Meta-Analysis.

Nikita Lakomkin, Jonathan Pan, Laura Stein, Brijesh Malkani, Mandip Dhamoon, J Mocco,

<h4>Background and purpose</h4>Diffusion-weighted magnetic resonance imaging (DWI) detects early infarction in acute stroke. With the substantial progress in stroke therapies, the frequency of posttreatment DWI reversibility in modern stroke cohorts is currently unknown. The purpose of this study was to perform a systematic literature review examining the relationship between characteristics ... Read more >>

J Neuroimaging (Journal of neuroimaging : official journal of the American Society of Neuroimaging)
[2020, 30(4):471-476]

Cited: 2 times

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The Role of Imaging in Health Screening: Overview, Rationale of Screening, and Screening Economics.

David H Ballard, Kirsteen R Burton, Nikita Lakomkin, Shannon Kim, Prabhakar Rajiah, Midhir J Patel, Parisa Mazaheri, Gary J Whitman,

Imaging screening examinations are growing in their indications and volume to identify conditions at an early, treatable stage. The Radiology Research Alliance's 'Role of Imaging in Health Screening' Task Force provides a review of imaging-based screening rationale, economics, and describes established guidelines by various organizations. Various imaging modalities can be ... Read more >>

Acad Radiol (Academic radiology)
[2021, 28(4):540-547]

Cited: 1 time

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The Role of Imaging in Health Screening: Screening for Specific Conditions.

David H Ballard, Kirsteen R Burton, Nikita Lakomkin, Shannon Kim, Prabhakar Rajiah, Midhir J Patel, Parisa Mazaheri, Gary J Whitman,

There are well-established and emerging screening examinations aimed at identifying malignant and nonmalignant conditions at early, treatable stages. The Radiology Research Alliance's "Role of Imaging in Health Screening" Task Force provides a comprehensive review of specific imaging-based screening examinations. This work reviews and serves as a reference for screening examinations ... Read more >>

Acad Radiol (Academic radiology)
[2021, 28(4):548-563]

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Specific causes and predictors of readmissions following acute and chronic subdural hematoma evacuation.

Nikita Lakomkin, Christopher S Graffeo, Constantinos G Hadjipanayis,

Patients treated with craniotomy for subdural hematoma (SDH) evacuation have a higher readmission incidence when compared to other neurosurgical patients. Factors predictive of readmission following craniotomy for SDH are incompletely understood. The National Surgical Quality Improvement (NSQIP) database was queried for all patients treated by craniotomy for SDH of any ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2020, 75:35-39]

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The Relationship Between Medicaid Coverage and Outcomes Following Total Knee Arthroplasty: A Systematic Review.

Nikita Lakomkin, Lorraine Hutzler, Joseph A Bosco,

<h4>Background</h4>Access to elective total knee arthroplasty is important in the treatment of end-stage arthritis, and numerous initiatives, including Medicaid expansion, have sought to improve patients' ability to undergo this procedure. However, despite this, the role of Medicaid insurance in patient outcomes remains unclear. The purpose of this study was to ... Read more >>

JBJS Rev (JBJS reviews)
[2020, 8(4):e0085]

Cited: 2 times

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Identifying the most appropriate lumbar decompression patients for ambulatory surgery centers - A pilot study using inpatient and outpatient hospital data.

Nishit Mummareddy, Ranbir Ahluwalia, Scott L Zuckerman, Nikita Lakomkin, Anthony Asher, Clinton J Devin,

<h4>Introduction</h4>To minimize healthcare related costs, ambulatory surgery centers (ASCs) have become increasingly favored venues for outpatient spine surgery. Using a national cohort of patients undergoing elective lumbar decompression (LD) in an inpatient or outpatient hospital setting, the current objectives were to: 1) outline specific factors that were associated with complications, ... Read more >>

J Clin Neurosci (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia)
[2020, 72:206-210]

Cited: 1 time

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Comprehensive Wound Risk Stratification of Rib-Based Distraction Instrumentation Procedures.

Patrick J Cahill, Richard E Campbell, Nikita Lakomkin, John M Flynn, Michael L Nance, Oscar H Mayer, Jesse A Taylor, Keith D Baldwin, Robert M Campbell,

<h4>Study design</h4>Single-center retrospective analysis of a prospectively collected registry.<h4>Objectives</h4>Identify factors predictive of rib-based distraction (RBD) instrumentation wound complication. Create a risk stratification model for RBD instrumentation wound complication.<h4>Summary of background data</h4>RBD instrumentation procedures have a high rate of wound complications, often requiring unplanned operative treatment. Currently, there is a relative ... Read more >>

Spine Deform (Spine deformity)
[2019, 7(6):971-978]

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