Full Text Journal Articles by
Author Necla Benlier


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Assessment of Antioxidant Effect of Beta-Glucan on the Whole Blood Oxidative DNA Damage with the Comet Assay in Colorectal Cancer.

Necla Benlier, Nilay Uçar, Eda Öğüt, Havva Yeşil Çinkir, Mustafa Yildirim, Pınar Günel Karadeniz, Esra Küpeli Akkol, Haroon Khan, Eyüp Ilker Saygili,

<h4>Objective</h4>The present study aims to evaluate the antioxidant effect of beta glucan on oxidative DNA damage by comet assay.<h4>Methods</h4>A total of 19 adult females and males diagnosed with stage 3-4 colorectal cancer and a control group of 20 age-matched healthy subjects were enrolled in the study. Blood samples of the ... Read more >>

Curr Mol Pharmacol (Current molecular pharmacology)
[2021, :]

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Effective microRNAs in Ischemia/Reperfusion Before and After Bypass Graft Surgery in Coronary Artery Patients

Erman Kandilli, Şenay Görücü Yılmaz, Murat Yardımcı, Necla Benlier, Muradiye Nacak,

<h4>Background: </h4> Cardiovascular diseases (CVD) are among the causes of morbidity and mortality in the world. Significant advances have been made in the diagnosis, treatment and prognosis of CVD. New biomarkers and therapeutic targets are needed to reduce the incidence of this disease. Recently, there is growing evidence that circulating ... Read more >>

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The role of endothelial nitric oxide synthase gene polymorphisms in patients with lung cancer.

Canan Koçer, Necla Benlier, Sibel Oğuzkan Balci, Sacide Pehlivan, Maruf Şanli, Muradiye Nacak,

<h4>Objectives</h4>Lung cancer is a disease characterized by uncontrolled cell growth in the lung tissues. The most common causes of lung cancer include smoking, exposure to radon gas, asbestos, environmental pollutants as well as genetic factors. Nitric oxide (NO) has potential mutagenic and carcinogenic activity and may play an important role ... Read more >>

Clin Respir J (The clinical respiratory journal)
[2020, 14(10):948-955]

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A novel diagnostic tool for the detection of bladder cancer: Measurement of urinary high mobility group box-1.

Necla Benlier, Mehmet Solakhan, Zeliha Yıldırım, Vildan Kaya, Ömer Aydın Yıldırım, Nuri Orhan, Hülya Çiçek, Mustafa Yıldırım,

<h4>Objective</h4>We aimed to investigate the diagnostic value of urinary High Mobility Group Box-1 (HMGB1) level as a noninvasive tool that can be potentially used for diagnosis and during follow-up in patients with bladder cancer patients.<h4>Method</h4>The study was conducted in a total of 121 participants including 61 patients diagnosed with primary ... Read more >>

Urol Oncol (Urologic oncology)
[2020, 38(8):685.e11-685.e16]

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Childhood Obesity Risk in Relationship to Perilipin 1 (PLIN1) Gene Regulation by Circulating microRNAs.

Şenay Görücü Yılmaz, Hakan Bozkurt, Arinao Ndadza, Nicholas Ekow Thomford, Murat Karaoğlan, Mehmet Keskin, Necla Benlier, Collet Dandara,

Childhood obesity is a growing public health burden in many countries. The lipid perilipin 1 (<i>PLIN1</i>) gene is involved in regulation of lipolysis, and thus represents a viable candidate mechanism for obesity genetics research in children. In addition, the regulation of candidate gene expression by circulating microRNAs (miRNAs) offers a ... Read more >>

OMICS (Omics : a journal of integrative biology)
[2020, 24(1):43-50]

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Neck pain: is it part of a migraine attack or a trigger before a migraine attack?

Gökhan Özer, Necla Benlier,

<h4>Background</h4>A migraine is a primary headache disorder characterized by recurrent headaches that are moderate to severe. Neck pain may actually be the most common migraine symptom despite the fact that it is rarely listed among usual symptoms such as nausea and light sensitivity. The aim of this study is to ... Read more >>

Acta Neurol Belg (Acta neurologica Belgica)
[2020, 120(2):289-293]

Cited: 1 time

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Association of high mobility group box 1 protein with coronary artery disease.

Necla Benlier, Mustafa Bilge Erdoğan, Serdar Keçioğlu, Nuri Orhan, Hülya Çiçek,

<h4>Background</h4>Recently, the role of inflammation in coronary artery disease and the association of inflammatory biomarkers with adverse outcomes have been investigated in many studies. We investigated the relationship between high serum mobility group box 1 protein levels and established risk factors for coronary artery disease.<h4>Methods</h4>Fifty-five patients who presented to our ... Read more >>

Asian Cardiovasc Thorac Ann (Asian cardiovascular & thoracic annals)
[2019, 27(4):251-255]

Cited: 3 times

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Childhood obesity and the role of dopamine D2 receptor and cannabinoid receptor-1 gene polymorphisms.

Nilgun Col Araz, Muradiye Nacak, Sibel Oguzkan Balci, Necla Benlier, Mustafa Araz, Sacide Pehlivan, Ayse Balat, A Sukru Aynacioglu,

<h4>Aims</h4>The dopaminergic and endocannabinoid systems are involved in regulation of feeding behavior. The aim of the study is to examine the possible relation between polymorphisms of the dopamine D2 receptor (DRD2) and cannabinoid receptor-1 (CNR1) genes and childhood obesity.<h4>Methods</h4>A hundred obese children and 100 healthy controls were analyzed for DRD2 ... Read more >>

Genet Test Mol Biomarkers (Genetic testing and molecular biomarkers)
[2012, 16(12):1408-1412]

Cited: 5 times

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Analysis of dopamine D2 receptor (DRD2) gene polymorphisms in cannabinoid addicts.

Muradiye Nacak, Aysun B Isir, Sibel O Balci, Sacide Pehlivan, Necla Benlier, Sukru Aynacioglu,

The gene encoding the dopamine D2 receptor (DRD2) has been suggested as a candidate gene for substance dependence. In this study, the possible association between Taq1A and Taq1B DRD2 polymorphisms and cannabinoid dependence was investigated. One hundred and twelve cannabinoid addicted and 130 healthy control subjects were included in this ... Read more >>

J Forensic Sci (Journal of forensic sciences)
[2012, 57(6):1621-1624]

Cited: 8 times

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