Full Text Journal Articles by
Author Navneet Singh

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Complex redo surgery to treat a large thymoma invading the right atrium.

Navneet Singh, Parma Nand, Peter Alison,

BACKGROUND AND AIM:Anterior mediastinal masses which invade the great vessels and heart are rare. We report a case of a 76-year-old male presenting with a large invasive anterior mediastinal mass following recent cardiac surgery (coronary artery bypass grafting and aortic valve replacement via sternotomy). MATERIALS AND METHODS:This is a case ... Read more >>

J Card Surg (Journal of cardiac surgery)
[2020, :]

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Chest CT imaging of an early Canadian case of COVID-19 in a 28-year-old man.

Navneet Singh, Jennifer Fratesi,

CMAJ (CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne)
[2020, 192(17):E455]

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Utility and safety of maintenance chemotherapy in advanced non-small cell lung cancer across various performance status categories: real-world experience.

Kuruswamy Thurai Prasad, Valliappan Muthu, Bivas Biswas, Prabhat Singh Malik, Deepak Dabkara, Sandip Ganguly, Joydeep Ghosh, Babita Kataria, Sachin Khurana, Saurav Verma, Navneet Singh,

Maintenance chemotherapy (MC) with pemetrexed is a commonly used strategy in nonsquamous non-small cell lung cancer. However, most of the available evidence is from subjects with good performance status (PS), while data on the real-world utility and safety of this strategy in subjects with various categories of PS is limited. ... Read more >>

Curr Probl Cancer (Current problems in cancer)
[2020, :100565]

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Assessment of Bronchiectasis in HIV Patients among an Urban Population.

Veena Dronamraju, Navneet Singh, Justin Poon, Sachi Shah, Joseph Gorga, Hector Ojeda-Martinez, Samy McFarlane,

Bronchiectasis is characterized by permanent destruction of the airways that presents with productive cough, as well as bronchial wall thickening and luminal dilatation on computed tomographic (CT) scan of the chest; it is associated with high mortality. Accumulating data suggests higher rates of bronchiectasis among the HIV-positive population. This case ... Read more >>

Case Rep Pulmonol (Case reports in pulmonology)
[2020, 2020:8903809]

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Real world experience of treatment and outcome in ALK-rearranged metastatic nonsmall cell lung cancer: A multicenter study from India.

Amol Patel, Ullas Batra, Kuruswamy Thurai Prasad, Deepak Dabkara, Joydeep Ghosh, Manasi Sharma, Navneet Singh, P Suresh, Parveen Jain, Prabhat Singh Malik, Priyanshu Choudhary, Sandip Ganguly, Sachin Khurana, Shivashankara Ms, Sneha Bothra, Valliappan Muthu, Bivas Biswas,

BACKGROUND:Anaplastic lymphoma kinase (ALK) rearranged metastatic non-small cell lung cancer (NSCLC) comprises 5%-7% of all lung cancer and carries a good prognosis with available ALK-inhibitors. Majority of registration trials in ALK-inhibitors did not include Indian patients. Hence, this study was planned to analyze the outcome of Indian patients treated with ... Read more >>

Curr Probl Cancer (Current problems in cancer)
[2020, :100571]

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Herpes Simplex Virus Latency Is Noisier the Closer We Look.

Navneet Singh, David C Tscharke,

During herpes simplex virus (HSV) latency, the viral genome is harbored in peripheral neurons in the absence of infectious virus but with the potential to restart infection. Advances in epigenetics have helped explain how viral gene expression is largely inhibited during latency. Paradoxically, at the same time, the view that ... Read more >>

J. Virol. (Journal of virology)
[2020, 94(4):]

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Coagulopathy reversal in intracerebral haemorrhage.

Alexander Jacob Sweidan, Navneet Kaur Singh, Joseph Luke Conovaloff, Matthew Bower, Leonid I Groysman, Mohammad Shafie, Wengui Yu,

As intracerebral hemorrahge becomes more frequent as a result of an aging population with greater comorbidities, rapid identification and reversal of precipitators becomes increasingly paramount. The aformentioned population will ever more likely be on some form of anticoagulant therapy. Understanding the mechanisms of these agents and means by which to ... Read more >>

Stroke Vasc Neurol (Stroke and vascular neurology)
[2020, 5(1):29-33]

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Extensive-disease small cell lung cancer, multiple relapses, five lines of therapy and more than 10-year survival.

Pawan Kumar Singh, Deepa Kumari Shrestha, Navneet Singh, Nalini Gupta,

Small cell lung cancer (SCLC) accounts for nearly 18% of lung cancer cases. Most of the patients of SCLC are not surgical candidates, due to advanced stage at presentation hence only viable options are chemotherapy and radiotherapy. Long-term survival in SCLC is extremely rare due to relapses and comorbidities. Ten-year ... Read more >>

BMJ Case Rep (BMJ case reports)
[2020, 13(2):]

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Immune checkpoint inhibitors in advanced non-small cell lung cancer: A metacentric experience from India.

Santosh Kumar, Srujana Joga, Bivas Biswas, Deepak Dabkara, Kuruswamy Thurai Prasad, Navneet Singh, Prabhat Singh Malik, Sachin Khurana, Sandip Ganguly, Valliappan Muthu, Ullas Batra,

BACKGROUND:Immune check point inhibitors (ICIs) have changed the treatment paradigm of driver mutation negative non-small cell lung cancer (NSCLC) and they are increasingly incorporated in first-line treatment. Real-world experience of use of these drugs is limited. We aim to evaluate the real-world experience of use of ICIs in patients with ... Read more >>

Curr Probl Cancer (Current problems in cancer)
[2020, :100549]

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A review of the genus Cyana Walker, 1854 from India, with descriptions of five new species and three new subspecies (Lepidoptera: Erebidae: Arctiinae: Lithosiini).

Navneet Singh, Anton V Volynkin, Jagbir Singh Kirti, Harvinder Singh Datta, Maria S Ivanova,

Indian taxa of the genus Cyana Walker, 1854 are reviewed. Five new species and three new subspecies are described: C. rudloffi Volynkin N. Singh, sp. nov., C. atlanteia N. Singh et al., sp. nov., C. chrysopeleia N. Singh et al., sp. nov., C. dohertyi eirene Volynkin N. Singh, ssp. nov., ... Read more >>

Zootaxa (Zootaxa)
[2020, 4738(1):zootaxa.4738.1.1]

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Unearthing EGFR Mutations and the Rewards of Persistence in Precision Oncology: Breaching the 10-Year Survival Barrier in Metastatic NSCLC With Active Disease.

Pawan Kumar Singh, Rajender Kumar, Amanjit Bal, Nalini Gupta, Rakesh Kapoor, Kuruswamy Thurai Prasad, Navneet Singh,

JCO Glob Oncol (JCO global oncology)
[2020, 6:174-179]

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Therapy for Stage IV Non-Small-Cell Lung Cancer Without Driver Alterations: ASCO and OH (CCO) Joint Guideline Update.

Nasser H Hanna, Bryan J Schneider, Sarah Temin, Sherman Baker, Julie Brahmer, Peter M Ellis, Laurie E Gaspar, Rami Y Haddad, Paul J Hesketh, Dharamvir Jain, Ishmael Jaiyesimi, David H Johnson, Natasha B Leighl, Tanyanika Phillips, Gregory J Riely, Andrew G Robinson, Rafael Rosell, Joan H Schiller, Navneet Singh, David R Spigel, Janis O Stabler, Joan Tashbar, Gregory Masters,

PURPOSE:The aim of this work is to provide evidence-based recommendations updating the 2017 ASCO guideline on systemic therapy for patients with stage IV non-small-cell lung cancer (NSCLC) without driver alterations. A guideline update for patients with stage IV NSCLC with driver alterations will be published separately. METHODS:The American Society of ... Read more >>

J. Clin. Oncol. (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2020, 38(14):1608-1632]

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Lung Cancer Surveillance After Definitive Curative-Intent Therapy: ASCO Guideline.

Bryan J Schneider, Nofisat Ismaila, Joachim Aerts, Caroline Chiles, Megan E Daly, Frank C Detterbeck, Jason W D Hearn, Sharyn I Katz, Natasha B Leighl, Benjamin Levy, Bryan Meyers, Septimiu Murgu, Larissa Nekhlyudov, Edgardo S Santos, Navneet Singh, Joan Tashbar, David Yankelevitz, Nasser Altorki,

PURPOSE:To provide evidence-based recommendations to practicing clinicians on radiographic imaging and biomarker surveillance strategies after definitive curative-intent therapy in patients with stage I-III non-small-cell lung cancer (NSCLC) and SCLC. METHODS:ASCO convened an Expert Panel of medical oncology, thoracic surgery, radiation oncology, pulmonary, radiology, primary care, and advocacy experts to conduct ... Read more >>

J. Clin. Oncol. (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2020, 38(7):753-766]

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The IASLC Lung Cancer Staging Project: Analysis of Resection Margin Status and Proposals for Residual Tumor Descriptors for Non-Small Cell Lung Cancer.

John G Edwards, Kari Chansky, Paul Van Schil, Andrew G Nicholson, Souheil Boubia, Elisabeth Brambilla, Jessica Donington, Françoise Galateau-Sallé, Hans Hoffmann, Maurizio Infante, Mirella Marino, Edith M Marom, Jun Nakajima, Marcin Ostrowski, William D Travis, Ming-Sound Tsao, Yasushi Yatabe, Dorothy J Giroux, Lynn Shemanski, John Crowley, Marc Krasnik, Hisao Asamura, Ramón Rami-Porta, ,

OBJECTIVE:Our aim was to validate the prognostic relevance in NSCLC of potential residual tumor (R) descriptors, including the proposed International Association for the Study of Lung Cancer definition for uncertain resection, referred to as R(un). METHODS:A total of 14,712 patients undergoing resection with full R status and survival were analyzed. ... Read more >>

J Thorac Oncol (Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer)
[2020, 15(3):344-359]

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XRCC1 632 as a candidate for cancer predisposition via a complex interaction with genetic variants of base excision repair and double strand break repair genes.

Amrita Singh, Navneet Singh, Digambar Behera, Siddharth Sharma,

Aim: The DNA repair system safeguards integrity of DNA. Genetic alterations force the improper repair which in conjugation with other factors ultimately results in carcinogenesis. Materials & methods: PCR-restriction fragment length polymorphism was used for genotyping, which was followed by statistical analysis using logistic regression analysis, multifactor dimensionality reduction and classification ... Read more >>

Future Oncol (Future Oncology)
[2019, 15(33):3845-3859]

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Establishment of the new genus Parvuspina for an undescribed Lithosiini species of Asura/Miltochrista generic complex (Lepidoptera: Erebidae: Arctiinae).

Navneet Singh, Jagbir Singh Kirti, Harvinder Singh Datta,

The Asura/Miltochrista generic complex belongs to Lithosiini (Erebidae, Arctiinae). It is one of the most diverse and taxonomically unresolved groups of this tribe. At present, this generic complex includes about 25 valid genera, as well as several generic/specific taxa of unclear taxonomic status (Holloway 2001, Kirti Singh 2016, Volynkin 2017, ... Read more >>

Zootaxa (Zootaxa)
[2019, 4686(1):zootaxa.4686.1.10]

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A review of the genus Dolgoma Moore from India, with notes on the genus taxonomy and descriptions of a new genus, four new species and a new subspecies (Lepidoptera, Erebidae, Arctiinae, Lithosiini).

Navneet Singh, Jagbir Singh Kirti, Harvinder Singh Datta, Rahul Joshi, Anton V Volynkin,

In the present paper, we review the genus Dolgoma from India, establish three species-groups and describe a new species, D. xanthoma N. Singh, Kirti, Datta Volynkin, sp. nov. and a new subspecies, D. rectoides arunachala N. Singh Joshi, ssp. nov. A new genus, Teuloma Volynkin N. Singh, gen. nov. is ... Read more >>

Zootaxa (Zootaxa)
[2019, 4683(1):zootaxa.4683.1.2]

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Stability behaviour of antiretroviral drugs and their combinations. 11: Characterization of interaction products of zidovudine and efavirenz, and evaluation of their anti HIV-1 activity, and physiochemical and ADMET properties.

Moolchand Kurmi, Archana Sahu, Ankit Balhara, Inder Pal Singh, Smita Kulkarni, Navneet Kumar Singh, Prabha Garg, Saranjit Singh,

Zidovudine (ZDV) and efavirenz (EFV), which belong to two separate classes of antiretroviral drugs, viz., NRTI and NNRTI, respectively, were subjected to different stability test conditions alone and in solid mixtures to evaluate possibility of interaction among them. The exposed samples were analyzed by high performance liquid chromatography (HPLC) using ... Read more >>

J Pharm Biomed Anal (Journal of pharmaceutical and biomedical analysis)
[2020, 178:112911]

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A Murine Cell Line Based Model of Chronic CDK9 Inhibition to Study Widespread Non-Genetic Transcriptional Elongation Defects (TEdeff) in Cancers.

Vishnu Modur, Navneet Singh, Belal Muhammad,

We have previously reported that a subset of cancers is defined by global transcriptional deregulations with widespread deficiencies in mRNA transcription elongation (TE)-we call such cancers as TEdeff. Notably, TEdeff cancers are characterized by spurious transcription and faulty mRNA processing in a large set of genes, such as interferon/JAK/STAT and ... Read more >>

J Vis Exp (Journal of visualized experiments : JoVE)
[2019, (151):]

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On the taxonomy of the genus Neadeloides Klima, 1939 (Crambidae: Pyraustinae) with description of a new species from India.

Navneet Singh, Jagbir Singh Kirti, Kailash Chandra, Harsimran Singh, Rahul Ranjan,

In the present paper, the genus Neadeloides is re-diagnosed and subdivided into two species groups: the N. cinerealis species-group and the N. nubilus species-group. A new species, belonging to N. nubilus species-group is described from India: Neadeloides nubilus N. Singh, Ranjan H. Singh, sp. nov. A checklist of the genus ... Read more >>

Zootaxa (Zootaxa)
[2019, 4664(2):zootaxa.4664.2.10]

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An elderly woman with cervical lymphadenopathy and lung mass.

Parikshaa Gupta, Kuruswamy T Prasad, Navneet Singh, Radhika Srinivasan, Nalini Gupta, Ritambhara Nada, Arvind Rajwanshi,

Cytopathology (Cytopathology : official journal of the British Society for Clinical Cytology)
[2019, 30(6):679-682]

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A new species of the genus Toccolosida Walker, 1863 from India (Lepidoptera: Pyralidae: Pyralinae).

Navneet Singh, Kailash Chandra, Jagbir Singh Kirti, Rahul Ranjan,

The genus Toccolosida Walker, 1863 is a member of the Pyralini tribe of the subfamily Pyralinae in the family Pyralidae. It was described as a monotypic genus for Toccolosida rubriceps Walker, 1863 from Sikkim. Snellen (1890, 1892) described two additional species of Toccolosida, T. pallifrons Snellen, 1890 from Sikkim and ... Read more >>

Zootaxa (Zootaxa)
[2019, 4656(1):zootaxa.4656.1.12]

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Car seat survey at a children's hospital: need a booster?

Navneet Singh, Julie Chambers, James Hamill,

AIM:Child restraint practices among New Zealand children have fallen short of best practice recommendations. In 2013, New Zealand child restraint legislation was amended. The aim of the present study was to determine the child restraint practices of a cohort of children admitted to hospital and how practices have changed since ... Read more >>

N. Z. Med. J. (The New Zealand medical journal)
[2019, 132(1500):59-69]

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Longitudinal evaluation of the association between Insulin-like growth factor-1, Bone specific alkaline phosphatase and changes in mandibular length.

Tulika Tripathi, Prateek Gupta, Priyank Rai, Jitender Sharma, Vinod Kumar Gupta, Navneet Singh, Mahesh Verma,

The aim of the current longitudinal study was to assess the levels of serum Bone-specific alkaline phosphatase (BALP) and serum Insulin like growth factor-1 (IGF-1) in different cervical vertebral maturation index (CVMI) stages and observe their association with the mandibular growth. Blood samples and lateral cephalograms of 63 subjects (age ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):11582]

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Intensity and duration of lifestyle interventions for long-term weight loss and association with mortality: a meta-analysis of randomised trials.

Navneet Singh, Ralph Alan Huston Stewart, Jocelyne Rachelle Benatar,

OBJECTIVES:To evaluate the importance of the frequency and duration of lifestyle interventions for achieving weight loss over ≥1 year and associations with all-cause mortality. DESIGN:Meta-analysis of randomised trials using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and RevMan software version 5·2 (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen). ... Read more >>

BMJ Open (BMJ open)
[2019, 9(8):e029966]

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