Full Text Journal Articles by
Author Nasser M Malyar

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Feasibility and impact of carbon dioxide angiography on acute kidney injury following endovascular interventions in patients with peripheral artery disease and renal impairment.

Tim Jakobi, Matthias Meyborg, Eva Freisinger, Katrin Gebauer, Jacqueline Stella, Christiane Engelbertz, Holger Reinecke, Nasser M Malyar,

<h4>Background</h4>Post-contrast acute kidney injury (AKI) is a dreaded complication of endovascular revascularization using iodinated contrast medium in patients with peripheral artery disease and concomitant chronic kidney disease (CKD). This study sought to evaluate the incidence of AKI in patients with peripheral artery disease and CKD undergoing endovascular revascularization and using ... Read more >>

J Nephrol (Journal of nephrology)
[2021, 34(3):811-820]

Cited: 0 times

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Mortality after use of paclitaxel-based devices in peripheral arteries: a real-world safety analysis.

Eva Freisinger, Jeanette Koeppe, Joachim Gerss, Dennis Goerlich, Nasser M Malyar, Ursula Marschall, Andreas Faldum, Holger Reinecke,

<h4>Aims</h4>Drug-eluting devices (DED) represent a well-established therapy being widely used for endovascular revascularization (EVR) of peripheral vessels. Recent data indicate a two-fold increased long-term mortality in patients treated with paclitaxel-based DED. The subsequent safety concerns affected international regulatory authorities to enunciate several alerts for further application of DED.<h4>Methods and results</h4>In ... Read more >>

Eur Heart J (European heart journal)
[2020, 41(38):3732-3739]

Cited: 16 times

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Outcome of patients with chronic limb-threatening ischemia with and without revascularization.

Jacqueline Stella, Christiane Engelbertz, Katrin Gebauer, Juan Hassu, Matthias Meyborg, Eva Freisinger, Nasser M Malyar,

Background: Patients with chronic critical limb-threatening ischemia (CLTI) are at high risk of amputation and death. Despite the general recommendation for revascularization in CTLI in the guidelines, the underlying evidence for such a recommendation is limited. The aim of our study was to assess the outcome of patients with CLTI ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2020, 49(2):121-127]

Cited: 1 time

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Impact of diabetes type on treatment and outcome of patients with peripheral artery disease.

Lars Richter, Eva Freisinger, Florian Lüders, Katrin Gebauer, Matthias Meyborg, Nasser M Malyar,

<h4>Background</h4>The prevalence of diabetes mellitus and its associated complications such as peripheral artery disease is increasing worldwide. We aimed to explore the distinct impact of type 1 diabetes mellitus and type 2 diabetes mellitus on treatment and on short- and long-term outcome in patients with peripheral artery disease.<h4>Methods</h4>Retrospective analysis of ... Read more >>

Diab Vasc Dis Res (Diabetes & vascular disease research)
[2018, 15(6):504-510]

Cited: 2 times

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Nationwide Routine-Data Analysis of Sex Differences in Outcome of Acute Myocardial Infarction.

Eva Freisinger, Susanne Sehner, Nasser M Malyar, Anna Suling, Holger Reinecke, Karl Wegscheider,

Women have been reported to suffer from impaired outcome after acute myocardial infarction (AMI). The aim of our study was to determine the impact of sex and age on utilization of inpatient healthcare and outcome in patients with AMI (STEMI and NSTEMI) in a real-life setting. We performed a routine-data-based ... Read more >>

Clin Cardiol (Clinical cardiology)
[2018, 41(8):1013-1021]

Cited: 5 times

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Low rate of revascularization procedures and poor prognosis particularly in male patients with peripheral artery disease - A propensity score matched analysis.

Eva Freisinger, Nasser M Malyar, Holger Reinecke, Michael Unrath,

BACKGROUND:Few data discuss the impact of sex on diagnostic and therapeutic procedures and outcome of patients with peripheral artery disease (PAD). METHODS:We obtained data on 41,873 PAD patients between 2009 and 2011 (including a 4-year follow-up) from the largest German public health insurance (BARMER GEK). Propensity Score Matching (PSM) was ... Read more >>

Int J Cardiol (International journal of cardiology)
[2018, 255:188-194]

Cited: 1 time

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Prevalence and impact of critical limb ischaemia on in-hospital outcome in transcatheter aortic valve implantation in Germany.

Nasser M Malyar, Klaus Kaier, Eva Freisinger, Florian Lüders, Gerrit Kaleschke, Helmut Baumgartner, Lutz Frankenstein, Holger Reinecke, Jochen Reinöhl,

<h4>Aims</h4>Peripheral artery disease (PAD) is common in patients with aortic valve stenosis (AS). This study sought to assess the prevalence of critical limb ischaemia (CLI) and its impact on in-hospital outcome in patients undergoing transcatheter aortic valve implantation (TAVI) for severe AS.<h4>Methods and results</h4>All isolated TAVI procedures for AS in ... Read more >>

EuroIntervention (EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology)
[2017, 13(11):1281-1287]

Cited: 0 times

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Rationale and design of the RECording COurses of vasculaR Diseases registry (RECCORD registry).

Nasser M Malyar, Jürgen Stausberg, Wulf D Ito, Heinz Kölble, Ralf Langhoff, Holger Lawall, Michael Lichtenberg, Jens Stegemann, Marcus Treitl, Norbert Weiss, Ulrich Hoffmann,

<h4>Background</h4>The prevalence of peripheral artery disease (PAD) is increasing worldwide. Revascularization procedures constitute a cornerstone of the therapy in PAD, not only in critical limb ischaemia but increasingly also in patients with intermittent claudication. The German Society of Angiology - Society for Vascular Medicine is establishing a nationwide, prospective, multicentre ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2017, 46(4):262-267]

Cited: 1 time

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Association of CKD with Outcomes Among Patients Undergoing Transcatheter Aortic Valve Implantation.

Florian Lüders, Klaus Kaier, Gerrit Kaleschke, Katrin Gebauer, Matthias Meyborg, Nasser M Malyar, Eva Freisinger, Helmut Baumgartner, Holger Reinecke, Jochen Reinöhl,

<h4>Background and objectives</h4>Despitethe multiple depicted associations of CKD with reduced cardiovascular and overall prognoses, the association of CKD with outcome of patients undergoing transcatheter aortic valve implantation has still not been well described.<h4>Design, setting, participants, & measurements</h4>Data from all hospitalized patients who underwent transcatheter aortic valve implantation procedures between January ... Read more >>

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2017, 12(5):718-726]

Cited: 3 times

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Impact of diabetes on outcome in critical limb ischemia with tissue loss: a large-scaled routine data analysis.

Eva Freisinger, Nasser M Malyar, Holger Reinecke, Holger Lawall,

<h4>Background</h4>Patients with diabetes concomitant to critical limb ischemia (CLI) represent a sub-group at particular risk. Objective of this analysis is to evaluate the actual impact of diabetes on treatment, outcome, and costs in a real-world scenario in Germany.<h4>Methods</h4>We obtained routine-data on 15,332 patients with CLI with tissue loss from the ... Read more >>

Cardiovasc Diabetol (Cardiovascular diabetology)
[2017, 16(1):41]

Cited: 14 times

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Aging and Outcome in Patients With Peripheral Artery Disease and Critical Limb Ischemia.

Saskia Skonetzki, Florian Lüders, Christiane Engelbertz, Nasser M Malyar, Eva Freisinger, Matthias Meyborg, Holger Reinecke,

<h4>Background, objectives, design</h4>Aging of the population is one of the major challenges facing public health systems. The impact of aging on acute and long-term outcome of patients with peripheral artery disease (PAD) and critical limb ischemia (CLI) is currently not sufficiently clarified. This analysis consists of comprehensive, anonymized data obtained ... Read more >>

J Am Med Dir Assoc (Journal of the American Medical Directors Association)
[2016, 17(10):927-932]

Cited: 2 times

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The Impact of Chronic Kidney Disease on Hospitalized Patients With Peripheral Arterial Disease and Critical Limb Ischemia.

Florian Lüders, Torsten Fürstenberg, Christiane Engelbertz, Katrin Gebauer, Matthias Meyborg, Nasser M Malyar, Holger Reinecke,

Peripheral arterial disease (PAD) and chronic kidney disease (CKD) are major public health problems worldwide. Evaluations of large-scale data on morbidity, outcome, and costs in patients having PAD with CKD are essential. Cross-sectional nationwide population-based analysis of all hospitalizations for PAD during 2009 in Germany focused on the stage-related impact ... Read more >>

Angiology (Angiology)
[2017, 68(2):145-150]

Cited: 4 times

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CKD and Acute and Long-Term Outcome of Patients with Peripheral Artery Disease and Critical Limb Ischemia.

Florian Lüders, Holger Bunzemeier, Christiane Engelbertz, Nasser M Malyar, Matthias Meyborg, Norbert Roeder, Klaus Berger, Holger Reinecke,

<h4>Background and objectives</h4>Despite the many studies showing an association between CKD and a high risk of ischemic events and mortality, the association of CKD with peripheral arterial disease (PAD) still has not been well described.<h4>Design, setting, participants, & measurements</h4>This large cohort study assessed the association of CKD, even in the ... Read more >>

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2016, 11(2):216-222]

Cited: 16 times

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Amputations and mortality in in-hospital treated patients with peripheral artery disease and diabetic foot syndrome.

Nasser M Malyar, Eva Freisinger, Matthias Meyborg, Florian Lüders, Katrin Gebauer, Holger Reinecke, Holger Lawall,

<h4>Aims</h4>The prevalence of diabetes mellitus (DM) and its associated complications such as peripheral artery disease (PAD) and diabetic foot syndrome (DFS) are increasing worldwide. We aimed to determine the contemporary acute and long-term outcome of patients with PAD and DFS in Germany.<h4>Methods</h4>Nationwide, anonymized data of 40,335 patients hospitalized for PAD ... Read more >>

J Diabetes Complications (Journal of diabetes and its complications)
[2016, 30(6):1117-1122]

Cited: 14 times

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Acute and chronic anemia and short- and long-term outcome of patients with peripheral arterial disease and critical limb ischemia.

Florian Lüders, Christiane Engelbertz, Matthias Meyborg, Eva Freisinger, Nasser M Malyar, Thomas Zeller, Holger Reinecke,

<h4>Background</h4>Evident data about the additive effect of "the fifth cardiovascular risk factor" (anemia) and peripheral arterial disease (PAD) focused on morbidity and outcome of patients with PAD are currently still missing.<h4>Methods and results</h4>A total of 41,882 PAD patients were included. Of these, 5566 (13.3%) suffered from anemia. Patients with anemia ... Read more >>

Eur J Intern Med (European journal of internal medicine)
[2016, 31:62-67]

Cited: 2 times

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Long-term mortality after invasive diagnostic and endovascular revascularization in PAD patients.

Eva M Broich, Holger Reinecke, Nasser M Malyar, Matthias Meyborg, Katrin Gebauer,

<h4>Background</h4>The aim of this study was to assess the long-term, all-cause mortality among PAD patients hospitalized for invasive diagnostics and/or endovascular revascularization (ER) and the applied secondary prevention management.<h4>Methods</h4>From 2005 to 2009, at our center 582 consecutive patients underwent invasive peripheral angiography in part in combination with coronary angiography and/or ... Read more >>

Int Angiol (International angiology : a journal of the International Union of Angiology)
[2016, 35(5):516-525]

Cited: 0 times

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Low Rates of Revascularization and High In-Hospital Mortality in Patients With Ischemic Lower Limb Amputation: Morbidity and Mortality of Ischemic Amputation.

Nasser M Malyar, Eva Freisinger, Matthias Meyborg, Florian Lüders, Torsten Fürstenberg, Knut Kröger, Giovanni Torsello, Holger Reinecke,

<h4>Background</h4>To assess the nationwide contemporary burden of cardiovascular risk factors, comorbidities, and in-hospital mortality in patients with lower limb amputation (LLA) due to peripheral arterial disease and critical limb ischemia (CLI) in Germany.<h4>Methods</h4>German nationwide data for 2005 and 2009 were analyzed regarding in-hospital rates of major and minor ischemic LLA, ... Read more >>

Angiology (Angiology)
[2016, 67(9):860-869]

Cited: 13 times

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Peripheral artery disease is associated with high in-hospital mortality particularly in males with acute myocardial infarction in a nationwide real-world setting.

Eva Freisinger, Nasser M Malyar, Holger Reinecke,

<h4>Background</h4>Patients with peripheral arterial disease (PAD) are at high risk for cardiovascular morbidity and mortality. The objective of this nationwide analysis was to explore the association of PAD with in-hospital mortality in patients hospitalized for acute myocardial infarction (AMI).<h4>Patients and methods</h4>Data on all in-patient hospitalizations in Germany are continuously transferred ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2016, 45(2):169-174]

Cited: 5 times

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Outcome of patients with reduced ankle brachial index undergoing open heart surgery with cardiopulmonary bypass.

Matthias Meyborg, Zila Abdi-Tabari, Andreas Hoffmeier, Christiane Engelbertz, Florian Lüders, Eva Freisinger, Nasser M Malyar, Sven Martens, Holger Reinecke,

<h4>Objectives</h4>In open heart surgery using cardiopulmonary bypass, perfusion of the lower extremities is markedly reduced which may induce critical ischaemia in patients with pre-existing peripheral artery disease. Whether these patients have an increased risk for amputation and should better undergo peripheral revascularization prior to surgery remains unclear.<h4>Methods</h4>From 1 January 2009 ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2016, 49(5):1457-1461]

Cited: 0 times

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Restenosis after endovascular revascularization in peripheral artery disease.

Nasser M Malyar, Holger Reinecke, Eva Freisinger,

Endovascular revascularization (EVR) plays a leading role in the therapy of peripheral artery disease. The acute success rates of EVR in all anatomic territories and of all TASC lesions are excellent (> 95%). However, the occurrence of restenoses after EVR such as percutaneous transluminal angioplasty and particularly after stenting, poses ... Read more >>

Vasa (VASA. Zeitschrift fur Gefasskrankheiten)
[2015, 44(4):257-270]

Cited: 6 times

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Long-Term Mortality After Invasive Angiography and Endovascular Revascularization in Patients With PAD Having Chronic Kidney Disease.

Katrin Gebauer, Christiane Engelbertz, Nasser M Malyar, Matthias Meyborg, Florian Lüders, Eva Freisinger, Holger Reinecke,

Peripheral arterial disease (PAD) and chronic kidney disease (CKD) are associated with increased mortality rates. We assessed long-term outcomes of patients with PAD and CKD. Patients with PAD undergoing invasive angiography and/or endovascular revascularization between 2005 and 2010 were retrospectively classified into 5 CKD stages. A follow-up was performed and ... Read more >>

Angiology (Angiology)
[2016, 67(6):556-564]

Cited: 5 times

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Atrial fibrillation is a risk marker for worse in-hospital and long-term outcome in patients with peripheral artery disease.

Kristina Wasmer, Michael Unrath, Julia Köbe, Nasser M Malyar, Eva Freisinger, Matthias Meyborg, Günter Breithardt, Lars Eckardt, Holger Reinecke,

<h4>Objectives</h4>To investigate the relevance of atrial fibrillation or flutter (AF) for outcome of patients who are hospitalized for peripheral artery disease (PAD) and/or critical limb ischemia (CLI).<h4>Methods and results</h4>We compared baseline data, co-morbidities, procedural data as well as in-hospital and long-term outcome of 41,882 patients who were hospitalized with PAD ... Read more >>

Int J Cardiol (International journal of cardiology)
[2015, 199:223-228]

Cited: 8 times

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Peripheral arterial disease and critical limb ischaemia: still poor outcomes and lack of guideline adherence.

Holger Reinecke, Michael Unrath, Eva Freisinger, Holger Bunzemeier, Matthias Meyborg, Florian Lüders, Katrin Gebauer, Norbert Roeder, Klaus Berger, Nasser M Malyar,

<h4>Aims</h4>Only few and historic studies reported a bad prognosis of peripheral arterial disease (PAD) and critical limb ischaemia (CLI). The contemporary state of treatment and outcomes should be assessed.<h4>Methods and results</h4>From the largest public health insurance in Germany, all in- and outpatient diagnosis and procedural data were retrospectively obtained from ... Read more >>

Eur Heart J (European heart journal)
[2015, 36(15):932-938]

Cited: 94 times

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Autologous bone marrow mononuclear cell therapy improves symptoms in patients with end-stage peripheral arterial disease and reduces inflammation-associated parameters.

Nasser M Malyar, Stefan Radtke, Khalil Malyar, Jawed Arjumand, Peter A Horn, Knut Kröger, Eva Freisinger, Holger Reinecke, Bernd Giebel, Franz-Eduard Brock,

<h4>Background aims</h4>The purpose of this study was to evaluate the effect of autologous bone marrow mononuclear cells (BM-MNCs) on symptoms and perfusion indices in severely symptomatic patients with peripheral arterial disease (PAD) without further option for endovascular or surgical revascularization.<h4>Methods</h4>Only patients with severe symptomatic PAD (Fontaine class IIb-IV, Rutherford category ... Read more >>

Cytotherapy (Cytotherapy)
[2014, 16(9):1270-1279]

Cited: 6 times

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German nationwide data on current trends and management of acute myocardial infarction: discrepancies between trials and real-life.

Eva Freisinger, Torsten Fuerstenberg, Nasser M Malyar, Juergen Wellmann, Ulrich Keil, Guenter Breithardt, Holger Reinecke,

<h4>Aims</h4>Recent guidelines on acute myocardial infarction (AMI) are based on randomized clinical trials (RCTs) and registries with selected patients, and may therefore not represent 'real-life'. This analysis shows for the first time nationwide trends in AMI from Germany.<h4>Methods and results</h4>We were provided with data on all in-patient hospitalizations by the ... Read more >>

Eur Heart J (European heart journal)
[2014, 35(15):979-988]

Cited: 33 times

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