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Author Muhammad Bilal

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Pharmacokinetics of remdesivir in a COVID-19 patient with end-stage renal disease on intermittent haemodialysis.

Fritz Sörgel, Jakob J Malin, Henning Hagmann, Martina Kinzig, Muhammad Bilal, Dennis A Eichenauer, Oliver Scherf-Clavel, Alexander Simonis, Lobna El Tabei, Uwe Fuhr, Jan Rybniker,

J Antimicrob Chemother (The Journal of antimicrobial chemotherapy)
[2020, :]

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Armoring bio-catalysis via structural and functional coordination between nanostructured materials and lipases for tailored applications.

Muhammad Bilal, Hafiz M N Iqbal,

Nanostructured materials represent an interesting and novel class of support matrices for the immobilization of different enzymes. Owing to the high surface area, robust mechanical stability, outstanding optical, thermal, and electrical properties, nanomaterials have been rightly perceived as desired immobilization matrices for lipases immobilization with a wide array of biotechnological ... Read more >>

Int J Biol Macromol (International journal of biological macromolecules)
[2020, :]

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Prevalence of posttraumatic stress symptoms in health care workers after exposure to patients with COVID-19.

Hao Chen, Bin Wang, Yanbo Cheng, Bilal Muhammad, Shengli Li, Zhigang Miao, Bo Wan, Mannan Abdul, Zhong Zhao, Deqin Geng, Xingshun Xu,

Objective:To investigate the prevalence of posttraumatic stress symptoms (PTSS) of health care workers (HCWs) who were potentially or directly exposed to patients with coronavirus disease 2019 (COVID-19) in a non-core epidemic area of China. Methods:Psychological conditions were evaluated by the multiple psychological evaluation scales in HCWs at the Affiliated Hospital ... Read more >>

Neurobiol Stress (Neurobiology of stress)
[2020, 13:100261]

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Harnessing the biocatalytic attributes and applied perspectives of nanoengineered laccases-A review.

Muhammad Bilal, S Salman Ashraf, Jiandong Cui, Wen-Yong Lou, Marcelo Franco, Sikandar I Mulla, Hafiz M N Iqbal,

In the recent past, numerous new types of nanostructured carriers, as support matrices, have been engineered to advance the traditional enzyme immobilization strategies. The current research aimed to develop a robust enzyme-based biocatalytic platform and its effective deployment in the industrial biotechnology sectors at large and catalysis area, in particular, ... Read more >>

Int J Biol Macromol (International journal of biological macromolecules)
[2020, :]

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Pharmacokinetics of remdesivir in a COVID-19 patient with end-stage renal disease on intermittent hemodialysis

Fritz Sörgel, Jakob Malin, Henning Hagmann, Martina Kinzig, Muhammad Bilal, Dennis Eichenauer, Oliver Scherf-Clavel, Alexander Simonis, Lobna El Tabei, Uwe Fuhr, Jan Rybniker,

Abstract Remdesivir, a drug with provisional approval for the treatment of COVID-19, is not recommended in patients with an estimated glomerular filtration rate ≤ 30 mL/min. Here we provide a first detailed pharmacokinetic assessment of remdesivir and its major metabolites in a patient with end stage renal disease on hemodialysis. ... Read more >>

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The non-Newtonian maxwell nanofluid flow between two parallel rotating disks under the effects of magnetic field.

Ali Ahmadian, Muhammad Bilal, Muhammad Altaf Khan, Muhammad Imran Asjad,

The main feature of the present numerical model is to explore the behavior of Maxwell nanoliquid moving within two horizontal rotating disks. The disks are stretchable and subjected to a magnetic field in axial direction. The time dependent characteristics of thermal conductivity have been considered to scrutinize the heat transfer ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):17088]

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Study of the Effect of Different Hepatitis C Virus Genotypes on Splenomegaly

Alexander Muacevic, John R Adler, Muhammad Junaid Azhar, Noor Khalid, Shanza Azhar, Umer Irshad, Hassaan Ahmed, Tayyab Mumtaz Khan, Samat Habib, Zuha Ali, Yumnah Anwar, Muhammad Bilal,

Background Several recent studies have shown that the hepatitis C virus (HCV) and its different genotypes are a predominant and leading cause of cirrhosis and splenomegaly in different regions of the world. Advanced stage of cirrhosis leads to portal hypertension that causes splenomegaly. This complication may have many other manifestations ... Read more >>

Cureus (Cureus)
[0, 12(8):]

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L-Xylo-3-hexulose, a new rare sugar produced by the action of acetic acid bacteria on galactitol, an exception to Bertrand Hudson's rule.

Yirong Xu, Ping Chi, Jiyang Lv, Muhammad Bilal, Hairong Cheng,

BACKGROUND:In acetic acid bacteria such as Gluconobacter oxydans or Gluconobacter cerinus, pyrroloquinoline quinone (PQQ) in the periplasm serves as the redox cofactor for several membrane-bound dehydrogenases that oxidize polyhydric alcohols to rare sugars, which can be used as a healthy alternative for traditional sugars and sweeteners. These oxidation reactions obey ... Read more >>

Biochim Biophys Acta Gen Subj (Biochimica et biophysica acta. General subjects)
[2021, 1865(1):129740]

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Automatic Classification Approach for Detecting COVID-19 using Deep Convolutional Neural Networks

Sajib Sarker, Ling Tan, Ma Wen Jie, Rong Shan Shan, Md. Arfan Ali, Muhammad Bilal, Zhongfeng Qiu, Sanjit Kumar Mondal, Pravash Tiwari,

The COVID-19 pandemic situation has created even more difficulties in the quick identification and screening of the COVID-19 patients for the medical specialists. Therefore, a significant study is necessary for detecting COVID-19 cases using an automated diagnosis method, which can aid in controlling the spreading of the virus. In this ... Read more >>

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Pseudomonas spp. as cell factories (MCFs) for value-added products: from rational design to industrial applications.

Songwei Wang, Jiajia Cui, Muhammad Bilal, Hongbo Hu, Wei Wang, Xuehong Zhang,

In recent years, there has been increasing interest in microbial biotechnology for the production of value-added compounds from renewable resources. Pseudomonas species have been proposed as a suitable workhorse for high-value secondary metabolite production because of their unique characteristics for fast growth on sustainable carbon sources, a clear inherited background, ... Read more >>

Crit Rev Biotechnol (Critical reviews in biotechnology)
[2020, 40(8):1232-1249]

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Current perspective on diagnosis, epidemiological assessment, prevention strategies, and potential therapeutic interventions for severe acute respiratory infections caused by 2019 novel coronavirus (SARS-CoV-2).

Komal Rizwan, Tahir Rasheed, Shakeel Ahmad Khan, Muhammad Bilal, Tahir Mahmood,

Coronaviruses are single-stranded RNA viruses that cause severe respiratory, enteric, and systemic infections in a vast range of hosts, including man, fish, mammals, and avian. Scientific interest has heightened on coronaviruses after the emergence of the 2019 novel Coronavirus (SARS-CoV-2). This review provides current perspectives on morphology, genetic diversity, transmission ... Read more >>

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2020, :1-10]

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Bio-based active food packaging materials: Sustainable alternative to conventional petrochemical-based packaging materials.

Muhammad Asgher, Sarmad Ahmad Qamar, Muhammad Bilal, Hafiz M N Iqbal,

In food industry, a growing concern is the use of suitable packaging material (i.e., biodegradable coatings and films) with enhanced thermal, mechanical and barrier characteristics to prevent from contamination and loss of foodstuff. Biobased polymer resources can be used for the development of biodegradable bioplastics. To achieve this goal, biopolymers ... Read more >>

Food Res Int (Food research international (Ottawa, Ont.))
[2020, 137:109625]

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Study of the Effect of Different Hepatitis C Virus Genotypes on Splenomegaly.

Muhammad Junaid Azhar, Noor Khalid, Shanza Azhar, Umer Irshad, Hassaan Ahmed, Tayyab Mumtaz Khan, Samat Habib, Zuha Ali, Yumnah Anwar, Muhammad Bilal,

Background Several recent studies have shown that the hepatitis C virus (HCV) and its different genotypes are a predominant and leading cause of cirrhosis and splenomegaly in different regions of the world. Advanced stage of cirrhosis leads to portal hypertension that causes splenomegaly. This complication may have many other manifestations ... Read more >>

Cureus (Cureus)
[2020, 12(8):e10164]

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Prevalence of Nocturnal Enuresis Among Children Dwelling in Rural Areas of Sindh.

Muhammad Bilal, Abdul Haseeb, Alina Saeed, Aena Saeed, Tooba Sarwar, Sana Ahmed, Alina Ishaque, Maryam Raza,

Introduction Nocturnal enuresis (NE) is usually a condition of childhood and refers to involuntary urinary incontinence during sleep. Due to its impact on a child's mental and social health, it is important to determine the prevalence of this condition among a population. Therefore, the aim of our study is to ... Read more >>

Cureus (Cureus)
[2020, 12(8):e9590]

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Bio-purification of sugar industry wastewater and production of high-value industrial products with a zero-waste concept.

Muhammad Zohaib Nawaz, Muhammad Bilal, Arslan Tariq, Hafiz M N Iqbal, Huda Ahmed Alghamdi, Hairong Cheng,

In recent years, biorefinery approach with a zero-waste concept has gained a lot research impetus to boost the environment and bioeconomy in a sustainable manner. The wastewater from sugar industries contains miscellaneous compounds and need to be treated chemically or biologically before being discharged into water bodies. Efficient utilization of ... Read more >>

Crit Rev Food Sci Nutr (Critical reviews in food science and nutrition)
[2020, :1-18]

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Secure and Robust Machine Learning for Healthcare: A Survey.

Adnan Qayyum, Junaid Qadir, Muhammad Bilal, Ala Al-Fuqaha,

Recent years have witnessed widespread adoption of machine learning (ML)/deep learning (DL) techniques due to their superior performance for a variety of healthcare applications ranging from the prediction of cardiac arrest from one-dimensional heart signals to computer-aided diagnosis (CADx) using multi-dimensional medical images. Notwithstanding the impressive performance of ML/DL, there ... Read more >>

IEEE Rev Biomed Eng (IEEE reviews in biomedical engineering)
[2020, PP:]

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Lead phytoextraction by Pelargonium hortorum: Comparative assessment of EDTA and DIPA for Pb mobility and toxicity.

Muhammad Arshad, Neelam Naqvi, Iram Gul, Khurram Yaqoob, Muhammad Bilal, Jean Kallerhoff,

Soil amendments like ethylene-diamine-tetraacetic-acid (EDTA) have extensively been used for enhancing lead (Pb) phytoextraction. But due to its toxic effects, environment friendly substitute is required. Therefore, the present study was conducted to investigate the effect of EDTA and Di-iso-propanol-amine (DIPA) to enhance Pb phytoavailability and uptake by Pelargonium hortorum along ... Read more >>

Sci Total Environ (The Science of the total environment)
[2020, 748:141496]

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Sequence Variants in the WNT10B and TP63 Genes Underlying Isolated Split-Hand/Split-Foot Malformation.

Muhammad Bilal, Amir Hayat, Muhammad Umair, Asmat Ullah, Sundus Khawaja, Erum Malik, Margit Burmeister, Nousheen Bibi, Umm-E-Kalsoom, Muhammad Iqbal Memon, Sulman Basit, Wasim Ahmad, Bushra Khan,

Aims: Split-hand/split-foot malformation (SHFM) is a developmental and congenital limb malformation characterized by variable degrees of medial clefting or absence of one or more digits in hands and/or feet. The aim of this study was to identify the underlying cause of three consanguineous Pakistani families showing various types of SHFM-related ... Read more >>

Genet Test Mol Biomarkers (Genetic testing and molecular biomarkers)
[2020, 24(9):600-607]

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Corrigendum to "Combined Industrial Wastewater Treatment in Anaerobic Bioreactor Post-Treated in Constructed Wetland".

Bibi Saima Zeb, Qaisar Mahmood, Saima Jadoon, Arshid Pervez, Muhammad Irshad, Muhammad Bilal, Zulfiqar Ahmad Bhatti,

[This corrects the article DOI: 10.1155/2013/957853.]. ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:6102379]

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The Importance of Serum N-Terminal Pro-Brain Natriuretic Peptide and Endogenous Hydrogen Sulfide for Predicting Coronary Artery Lesions in Pediatric Kawasaki Disease Patients: Findings From a Tertiary Care Hospital in Karachi, Pakistan.

Muhammad Bilal, Abdul Haseeb, Alina Saeed, Muhammad Ahad Sher Khan,

Introduction Kawasaki disease (KD) is an idiopathic, acute systemic vasculitis typically affecting medium-sized blood vessels with an inclination towards the coronary arteries. There is no specific diagnostic test established for it yet. Hence, our study aims to evaluate serum N-terminal pro-brain natriuretic peptide (NT-proBNP), hydrogen sulfide (H2S), and interleukin-6 (IL-6) levels as ... Read more >>

Cureus (Cureus)
[2020, 12(7):e9016]

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IL-1β/IL-1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha-synuclein pathology in the olfactory bulb, substantia nigra and striatum.

Haichen Niu, Qian Wang, Weiguang Zhao, Jianxin Liu, Deguang Wang, Bilal Muhammad, Xiaoyu Liu, Ning Quan, Haoyu Zhang, Fang Zhang, Yong Wang, Haiying Li, Rongli Yang,

Olfactory dysfunction is one of the early symptoms seen in Parkinson's disease (PD). However, the mechanisms underlying olfactory pathology that impacts PD disease progression and post-mortem appearance of alpha-synuclein (α-Syn) inclusions in and beyond olfactory bulb in PD remain unclear. It has been suggested that environmental toxins inhaled through the ... Read more >>

Brain Pathol (Brain pathology (Zurich, Switzerland))
[2020, :]

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Giant Cell Tumor After Distal Radius Open Reduction and Internal Fixation in a Pregnant Woman: A Case Report.

Craig Siesel, Bilal Muhammad, Scott Weiner,

CASE:A 32-year-old pregnant woman presented with new wrist pain after a fall. She had undergone surgical repair to the same wrist 6 years previously for a distal radius fracture. At that time, there was no evidence of a bone lesion. Current radiographs revealed a radiolucent lesion in the metaepiphyseal region. ... Read more >>

JBJS Case Connect (JBJS case connector)
[2020, 10(3):e2000165]

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Ink Classification in Hyperspectral Images

Muhammad Bilal, Haris Ahmad, Muhammad Khizer Ali,

Hyperspectral imaging provides vital information about the objects and elements present inside the image. That’s why they are very useful in satellite imagery as well as image forensics. Hyperspectral document analysis (HSDI) can be used for document authentication using ink analysis which can provide sufficient information about the composition and ... Read more >>

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Morphophysiological and Comparative Metabolic Profiling of Purslane Genotypes (Portulaca oleracea L.) under Salt Stress.

Shah Zaman, Muhammad Bilal, Hongmei Du, Shengquan Che,

Purslane, a fleshy herbaceous plant, plays a pivotal role in various preventive and therapeutic purposes. To date, no report has documented the consequence of salt stress on metabolite accumulation in purslane. Herein, we proposed an insight into the metabolic and physiological traits of purslane under saline stress environments. The gas ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:4827045]

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Effect of co-application of wastewater and freshwater on the physiological properties and trace element content in Raphanus sativus: soil contamination and human health.

Natasha, Muhammad Shahid, Aneeza Sardar, Hasnain Anwar, Sana Khalid, Sajid Hussain Shah, Ali Haidar Shah, Muhammad Bilal,

Nowadays, the use of wastewater for crop irrigation is increasing at global scale mainly due to freshwater scarcity and economic benefits. However, the presence of different types of pollutants including the trace elements (TEs) poses a serious threat to environmental and human health. This pot study evaluated the effect of ... Read more >>

Environ Geochem Health (Environmental geochemistry and health)
[2020, :]

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