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Ethnobotanical survey of the medicinal flora of Harighal, Azad Jammu & Kashmir, Pakistan.

Muhammad Shoaib Amjad, Ujala Zahoor, Rainer W Bussmann, Muhammad Altaf, Syed Mubashar Hussain Gardazi, Arshad Mehmood Abbasi,

BACKGROUND:The present study is the first quantitative ethnobotanical evaluation of Harighal, an inaccessible and unexplored area of District Bagh Azad Jammu & Kashmir (AJK). The exploration, quantification, and comparison of ethnobotanical knowledge among different rural communities of the study area were mainly focused during field survey. METHODOLOGY:In total, 79 informants ... Read more >>

J Ethnobiol Ethnomed (Journal of ethnobiology and ethnomedicine)
[2020, 16(1):65]

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Ethno-veterinary uses of Poaceae in Punjab, Pakistan.

Muhammad Majeed, Khizar Hayat Bhatti, Muhammad Shoaib Amjad, Arshad Mehmood Abbasi, Rainer W Bussmann, Fahim Nawaz, Audil Rashid, Ansar Mehmood, Majid Mahmood, Wisal Muhammad Khan, Khawaja Shafique Ahmad,

Plant species of the Poaceae family are not only used as fodder and forage but also contribute substantially to the treatment of various health disorders, particularly in livestock. Consequently, the present study was aimed to document the therapeutic uses of Poaceae practiced by the inhabitants of the Punjab Province for ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241705]

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Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases.

Abu Hazafa, Ammara Batool, Saeed Ahmad, Muhammad Amjad, Sundas Nasir Chaudhry, Jamal Asad, Hasham Feroz Ghuman, Hafiza Madeeha Khan, Muhammad Naeem, Usman Ghani,

Humanin (HN) is a small mitochondrial-derived cytoprotective polypeptide encoded by mtDNA. HN exhibits protective effects in several cell types, including leukocytes, germ cells, neurons, tissues against cellular stress conditions and apoptosis through regulating various signaling mechanisms, such as JAK/STAT pathway and interaction of BCL-2 family of protein. HN is an ... Read more >>

Life Sci (Life sciences)
[2020, :118679]

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Therapeutic Efficacy of Urinile Against Gouty Arthritis.

Saeed Ahmad, Ejaz Mohiuddin, Syed Muhammad Ali Shah, Muhammad Akram, Muhammad Amjad, Jaweria Nisar, Muhammad Riaz, Naveed Munir, Ghulam Rasool,

Gout is arthritis caused due to Monosodium urate (MSU) crystals deposition occurring particularly in patients with associated comorbidities limiting the use of conventional therapies. This study was planned to evaluate the therapeutic efficacy of urinile (a herbal drug) for the treatment of gouty arthritis. Allopurinol was used as standard drug ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2020, 18(4):1559325820946934]

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Ethnobotanical survey of the medicinal flora of Harighal, Azad Jammu & Kashmir, Pakistan

Muhammad Shoaib Amjad, Ujala Zahoor, Rainer Bussmann, Muhammad Altaf, Syed Mubashar Hussain Gardazi, Arshad Mehmood Abbasi,

Abstract Background: The present study is the first quantitative ethnobotanical evaluation of Harighal, an inaccessible and unexplored area of District Bagh Azad Jammu and Kashmir (AJK). The exploration, quantification and comparison of ethnobotanical knowledge among different rural communities of the study area were mainly focused during field survey. Methodology: In ... Read more >>

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Fabrication of polyvinyl alcohol based fast dissolving oral strips of sumatriptan succinate and metoclopramide HCL.

Muhammad Zaman, Rabia Hassan, Sobia Razzaq, Asif Mahmood, Muhammad Wahab Amjad, Maria Abdul Ghafoor Raja, Asif Ali Qaisar, Abdul Majeed, Muhammad Hanif, Rana Azam Tahir,

Migraine is a throbbing condition, usually associated with nausea and vomiting and requires concurrent administration of anti-migraine along with anti-emetic therapy. The current study was undertaken with an aim to fabricate fast dissolving oral strips (FDOSs) containing Sumatriptan succinate (anti-migraine) and Metoclopramide HCl (anti-emetic) in combination without involving any superdisintegrant. ... Read more >>

Sci Prog (Science progress)
[2020, 103(4):36850420964302]

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Evaluation of ligustrazine based synthetic compounds for mechanism based antiproliferative effects.

Syed Nasir Abbas Bukhari, Nasser Hadal Alotaibi, Waqas Ahmad, Khalid Saad Alharbi, Mohamed A Abdelgawad, Mohammad M Al-Sanea, Muhammad Masood Ahmad, Muhammad Wahab Amjad, Maria Abdul Ghafoor Raja, Muhammad Ajaz Hussain,

BACKGROUND:Ligustrazine and chalcones have been reported previously for various biological activities including anticancer effects. OBJECTIVES:Based on the multitargeted biological activities approach of ligustrazine based chalcones, in current study 18 synthetic ligustrazine-containing α, β-unsaturated carbonyl-based 1, 3-Diphenyl-2-propen-1-one derivatives were evaluated for their inhibitory effects on growth of five different types of ... Read more >>

Med Chem (Medicinal chemistry (Shariqah (United Arab Emirates)))
[2020, :]

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Nanoparticles Based Intranasal Delivery of Drug to Treat Alzheimer's Disease: A Recent Update.

Manisha Pandey, Hira Choudhury, Rohit Kumar Verma, Viney Chawla, Subrat Kumar Bhattamisra, Bapi Gorain, Maria Abdul Ghafoor Raja, Muhammad Wahab Amjad,

Alzheimer Association Report (2019) stated that the 6th primary cause of death in the USA is Alzheimer's disease (AD) which leads to behaviour and cognitive impairment. Nearly 5.8 million peoples of all ages in the USA have suffered from this disease, including 5.6 million elderly populations. The statistics of the ... Read more >>

CNS Neurol Disord Drug Targets (CNS & neurological disorders drug targets)
[2020, :]

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The interrater reliability of dynamic leap and balance test in healthy and chronic ankle instability.

Abbis H Jaffri, Muhammad Amjad, Susan Saliba,

The primary aim of this study was to assess the interrater reliability of the Dynamic Leap and Balance Test (DLBT) in chronic ankle instability (CAI) and healthy groups. The secondary aim was to assess the differences in errors and time taken to complete the DLBT between the two groups for ... Read more >>

Scand J Med Sci Sports (Scandinavian journal of medicine & science in sports)
[2020, :]

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The use of fish and herptiles in traditional folk therapies in three districts of Chenab riverine area in Punjab, Pakistan.

Muhammad Altaf, Arshad Mehmood Abbasi, Muhammad Umair, Muhammad Shoaib Amjad, Kinza Irshad, Abdul Majid Khan,

BACKGROUND:Like botanical taxa, various species of animals are also used in traditional and modern health care systems. Present study was intended with the aim to document the traditional uses of herptile and fish species among the local communities in the vicinity of the River Chenab, Punjab Pakistan. METHOD:Data collected by ... Read more >>

J Ethnobiol Ethnomed (Journal of ethnobiology and ethnomedicine)
[2020, 16(1):38]

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Synthesis, characterization and application of novel MnO and CuO impregnated biochar composites to sequester arsenic (As) from water: Modeling, thermodynamics and reusability.

Muhammad Imran, Muhammad Mohsin Iqbal, Jibran Iqbal, Noor Samad Shah, Zia Ul Haq Khan, Behzad Murtaza, Muhammad Amjad, Shafaqat Ali, Muhammad Rizwan,

The present study aimed at enhancing the adsorption potential of novel nanocomposites of Sesbania bispinosa biochar (SBC) with copper oxide (SBC/CuO) and manganese oxide nanoparticles (SBC/MnO) for the efficient and inexpensive removal of environmentally concerned contaminant arsenic (As) from contaminated water at batch scale. The scanning electron microscopy (SEM), Fourier ... Read more >>

J Hazard Mater (Journal of hazardous materials)
[2021, 401:123338]

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Hydrogeochemical investigation of arsenic in drinking water of schools and age dependent risk assessment in Vehari District, Punjab Pakistan: a multivariate analysis.

Behzad Murtaza, Humaira Nazeer, Natasha, Muhammad Amjad, Muhammad Imran, Muhammad Shahid, Noor S Shah, Abu Bakr Umer Farooq, Muhammad Amjad, Ghulam Murtaza,

Globally, a large number of school-aged children is suffering from water-borne diseases, particularly in low-income countries. Arsenic (As) is a hazardous and potentially carcinogenic metal(loid) in drinking water. Nowadays, alarming levels of As have been reported in the groundwater of Vehari District, Punjab Pakistan. In this study, drinking water supplies ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2020, 27(24):30530-30541]

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Efficacy of Dexmedetomidine vs Morphine as an Adjunct in a Paravertebral Block with Bupivacaine in Postoperative Analgesia Following Modified Radical Mastectomy.

Malik Jamil Ahmed, Abaid Ur Rehman, Rana Muhammad Arshad, Muhammad Wasim Ali Amjad, Zeeshan Khan, Aamir Furqan,

Objective To observe the efficacy of dexmedetomidine vs morphine as an adjunct in a paravertebral block (PVB) with bupivacaine in postoperative analgesia following modified radical mastectomy. Study design This was a randomized controlled trial performed from June 2018 to August 2019 in the Department of Anesthesia, Bakhtawar Amin Medical and ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8231]

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Mechanism of Fatigue Crack Growth in Biomedical Alloy Ti-27Nb.

Muhammad Amjad, Saeed Badshah, Amer Farhan Rafique, Muhammad Adil Khattak, Rafi Ullah Khan, Wail Ismail Abdullah Harasani,

Implants are widely used in the human body for the replacement of affected bones. Fatigue failure is one of the serious concerns for implants. Therefore, understanding of the underlying mechanism leading to fatigue failure is important for the longevity of biomaterial implants. In this paper, the fracture toughness and fatigue ... Read more >>

Materials (Basel) (Materials (Basel, Switzerland))
[2020, 13(10):]

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Determinants of households' food insecurity with severity dimensions in Pakistan: Varying estimates using partial proportional odds model.

Muhammad Akbar, Rizwan Niaz, Muhammad Amjad,

This study is conducted to determine the impact of some selected socioeconomic and demographic factors on households' food insecurity in Pakistan. Data are taken from national-level survey Household Integrated Income and Consumption Survey 2015-2016. Inclusion of gender dimensions of some important factors and estimation of varying estimates at four severity ... Read more >>

Health Soc Care Community (Health & social care in the community)
[2020, 28(5):1698-1709]

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Ethno-veterinary practices of Poaceae taxa in Punjab, Pakistan

Muhammad Majeed, Khizar Hayat Bhatti, Muhammad Shoaib Amjad, Arshad Mehmood Abbasi, Audil Rashid, Fahim Nawaz, Ansar Mehmood, Majid Mahmood, Khawaja Shafique Ahmad,

Abstract Background: Plant species of Poaceae family are not only used as fodder and forage but also contribute substantially in the treatment of various health disorders, particularly in livestock. Consequently, present study was aimed to document the therapeutic uses Poaceae taxa by the inhabitants of the Punjab Province to treat ... Read more >>

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An Overview of the Molecular Methods in the Diagnosis of Gastrointestinal Infectious Diseases.

Muhammad Amjad,

Gastrointestinal infectious diseases are very common worldwide and an important cause of morbidity and mortality, particularly in infants in developing countries. Diarrhea and other intestinal infections are caused by a wide range of bacteria, viruses, protozoa, and parasites. Conventional diagnosis of these infections is performed by culture, microscopy, and antigen ... Read more >>

Int J Microbiol (International journal of microbiology)
[2020, 2020:8135724]

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Acid treated biochar enhances cadmium tolerance by restricting its uptake and improving physio-chemical attributes in quinoa (Chenopodium quinoa Willd.).

Muhammad Asif Naeem, Arslan Shabbir, Muhammad Amjad, Ghulam Abbas, Muhammad Imran, Behzad Murtaza, Muhammad Tahir, Amna Ahmad,

Heavy metals contamination of soil especially with cadmium (Cd) is a serious environmental concern in the current industrial era. Biochar serves as an excellent ameliorating agent depending upon its properties and application rates. In the pot scale study, effect of acid treated (AWSB) and untreated wheat straw biochar (WSB) was ... Read more >>

Ecotoxicol. Environ. Saf. (Ecotoxicology and environmental safety)
[2020, 191:110218]

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Comparative physiological and biochemical evaluation of salt and nickel tolerance mechanisms in two contrasting tomato genotypes

Muhammad Amjad, Nuzhat Ameen, Behzad Murtaza, Muhammad Imran, Muhammad Shahid, Ghulam Abbas, Muhammad A Naeem, Sven‐Erik Jacobsen,

Plant tolerance against a combination of abiotic stresses is a complex phenomenon, which involves various mechanisms. Physiological and biochemical analyses of salinity (NaCl) and nickel (Ni) tolerance in two contrasting tomato genotypes were performed in a hydroponics experiment. The tomato genotypes selected were proved to be tolerant (Naqeeb) and sensitive ... Read more >>

Physiol Plant (Physiologia plantarum)
[2020, 168(1):27-37]

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Experimental study on biological damage in bone in vibrational drilling.

Khurshid Alam, Muhammad Iqbal, Jamal Umer, Muhammad Amjad, Ahmed Al-Ghaithi,

BACKGROUND:Drilling is a well-known mechanical operation performed for fixing fracture at required locations in bone. The process may produce mechanical and thermal alterations in the structure of the bone and surrounding tissues leading to irreversible damage known as osteonecrosis. OBJECTIVE:The main purpose of this study was to measure the level ... Read more >>

Biomed Mater Eng (Bio-medical materials and engineering)
[2020, 31(5):269-277]

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Potential of siltstone and its composites with biochar and magnetite nanoparticles for the removal of cadmium from contaminated aqueous solutions: Batch and column scale studies.

Muhammad Imran, Zia Ul Haq Khan, Jibran Iqbal, Noor Samad Shah, Saima Muzammil, Shafaqat Ali, Nawshad Muhammad, Arwa Aziz, Behzad Murtaza, Muhammad Asif Naeem, Muhammad Amjad, Muhammad Shahid, Ali Zakir, Muhammad Rizwan,

The present study is the first attempt to evaluate the pilot and batch scale adsorption potential of siltstone (SS) and its nanocomposites with biochar (EDB/SS), magnetite nanoparticles (MNPs/SS) and MNPs/EDB/SS for Cd removal from contaminated water. The SS, EDB/SS, MNPs/SS and MNPs/EDB/SS were characterized with FTIR, XRD, BET, SEM, TEM, ... Read more >>

Environ Pollut (Environmental pollution (Barking, Essex : 1987))
[2020, 259:113938]

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A multivariate analysis of comparative effects of heavy metals on cellular biomarkers of phytoremediation using Brassica oleracea.

Natasha, Muhammad Shahid, Mazhar Saleem, Hasnain Anwar, Sana Khalid, Tasveer Zahra Tariq, Behzad Murtaza, Muhammad Amjad, Muhammad Asif Naeem,

The biochemical/physiological variations in plant responses to heavy metals stress govern plant's ability to phytoremediate/tolerate metals. So, the comparative effects of different types of heavy metals on various plant responses can better elucidate the mechanisms of metal toxicity and detoxification. This study compared the physiological modifications, photosynthetic performance and detoxification ... Read more >>

Int J Phytoremediation (International journal of phytoremediation)
[2020, 22(6):617-627]

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Magnetic resonance imaging findings in patients with initial manifestations of perianal fistulas.

Khawaja Bilal Waheed, Waseem Jan Shah, Bilal Altaf, Muhammad Amjad, Fawad Hameed, Sana Wasim, Muhammad Zia UlHassan, Zahra Mohammed Abuabdullah, Selvin Nesaraj Rajamonickam, Zechriah Jebakumar Arulanatham,

BACKGROUND:Crohn's disease (CD) is a serious cause of perianal disease and the incidence is increasing in Saudi Arabia. MR imaging may document specific features that may help to foresee Crohn's disease in patients making an initial presentation. OBJECTIVE:Present MR imaging findings of perianal fistulas in patients making an initial presentation. ... Read more >>

Ann Saudi Med (Annals of Saudi medicine)
[2020, 40(1):42-48]

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Nickel Toxicity Induced Changes in Nutrient Dynamics and Antioxidant Profiling in Two Maize (Zea mays L.) Hybrids.

Muhammad Amjad, Hasan Raza, Behzad Murtaza, Ghulam Abbas, Muhammad Imran, Muhammad Shahid, Muhammad Asif Naeem, Ali Zakir, Muhammad Mohsin Iqbal,

Abstract: Nickel (Ni) is among the essential micronutrient heavy metals utilized by plants. However, an elevated level of Ni causes serious concerns for plants' physiology and their survival. This study evaluated the mechanisms influencing the growth, physiology, and nutrient dynamics in two commercial maize hybrids (Syngenta and Pioneer) exposed to ... Read more >>

Plants (Basel) (Plants (Basel, Switzerland))
[2019, 9(1):]

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Compositional and health risk assessment of drinking water from health facilities of District Vehari, Pakistan.

Behzad Murtaza, Natasha, Muhammad Amjad, Muhammad Shahid, Muhammad Imran, Noor Samad Shah, Ghulam Abbas, Muhammad Asif Naeem, Muhammad Amjad,

Arsenic (As) is a potentially toxic and carcinogenic metalloid. It has gained considerable attention owing to its high ecotoxic nature. High As contamination of groundwater in scattered areas is the current status of Pakistan. A number of assessments exist for the As contamination of the drinking water in District Vehari, ... Read more >>

Environ Geochem Health (Environmental geochemistry and health)
[2020, 42(8):2425-2437]

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