Full Text Journal Articles by
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Foliar Applied Acetylsalicylic Acid Induced Growth and Key-Biochemical Changes in Chickpea (Cicer arietinum L.) Under Drought Stress.

Iqbal Hussain, Rizwan Rasheed, Muhammad Arslan Ashraf, Muhammad Mohsin, Syed Muhammad Ali Shah, Dr Abid Rashid, Muhammad Akram, Jaweria Nisar, Muhammad Riaz,

The exogenous application of acetylsalicylic acid (ASA) is stated to increase tolerance of plants against different environmental stresses. Therefore, the present study was planned to get insight into ASA-mediated regulation of growth, secondary metabolism, and oxidative defense in 2 chickpea varieties. Ten seeds of 2 chickpea varieties (DG-89 and Bittle-98) ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2020, 18(4):1559325820956801]

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Attenuation of Spatial Memory in 5xFAD Mice by Halting Cholinesterases, Oxidative Stress and Neuroinflammation Using a Cyclopentanone Derivative.

Rahim Ullah, Gowhar Ali, Nisar Ahmad, Muhammad Akram, Geeta Kumari, Muhammad Usman Amin, Muhammad Naveed Umar,

Alzheimer's disease (AD) is an irreversible and chronic neurological disorder that gradually destroys memory and thinking skills. The research study was designed to investigate the underlying molecular signaling involved in the neuroprotective effects of cyclopentanone derivative i.e., 2-(hydroxyl-(3-nitrophenyl)methyl)cyclopentanone (3NCP) as a therapeutic agent for AD. In this study, In vivo ... Read more >>

Pharmaceuticals (Basel) (Pharmaceuticals (Basel, Switzerland))
[2020, 13(10):]

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Towards to Optimal Wavelet Denoising Scheme-A Novel Spatial and Volumetric Mapping of Wavelet-Based Biomedical Data Smoothing.

Ladislav Stanke, Jan Kubicek, Dominik Vilimek, Marek Penhaker, Martin Cerny, Martin Augustynek, Nikola Slaninova, Muhammad Usman Akram,

Wavelet transformation is one of the most frequent procedures for data denoising, smoothing, decomposition, features extraction, and further related tasks. In order to perform such tasks, we need to select appropriate wavelet settings, including particular wavelet, decomposition level and other parameters, which form the wavelet transformation outputs. Selection of such ... Read more >>

Sensors (Basel) (Sensors (Basel, Switzerland))
[2020, 20(18):]

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Therapeutic Efficacy of Urinile Against Gouty Arthritis.

Saeed Ahmad, Ejaz Mohiuddin, Syed Muhammad Ali Shah, Muhammad Akram, Muhammad Amjad, Jaweria Nisar, Muhammad Riaz, Naveed Munir, Ghulam Rasool,

Gout is arthritis caused due to Monosodium urate (MSU) crystals deposition occurring particularly in patients with associated comorbidities limiting the use of conventional therapies. This study was planned to evaluate the therapeutic efficacy of urinile (a herbal drug) for the treatment of gouty arthritis. Allopurinol was used as standard drug ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2020, 18(4):1559325820946934]

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Method for efficient soluble expression and purification of recombinant human interleukin-15.

Nadeem Ahmed, Bakht Afroze, Rabia Abbas, Mohsin Ahmed Khan, Muhammad Akram, Saad Tahir, Shehman Bakht, Ayesha Munir, Ahmad Ali Shahid,

Periplasmic expression of recombinant proteins ensures the production of biologically active proteins in a correctly folded state with several key advantages. This research focused on the in-frame cloning of rhIL-15 in pET-20 (+) vector with pelB-leader sequence to direct the protein to the bacterial periplasm. The target construct periplasmic expression ... Read more >>

Protein Expr Purif (Protein expression and purification)
[2021, 177:105746]

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The Diagnostic Utility and Clinical Implications of Bronchoalveolar Lavage in Cancer Patients With Febrile Neutropenia and Lung Infiltrates.

Usman Khalid, Muhammad J Akram, Faheem M Butt, Mohammad B Ashraf, Faheem Khan,

Introduction Febrile neutropenia (FN) is a dreaded complication of cancer chemotherapy and frequently associated with respiratory infections. Flexible bronchoscopy (FB) serves as a useful diagnostic tool in this regard. Objective To determine the diagnostic yield, safety and clinical implications of bronchoalveolar lavage (BAL) in cancer patients with FN, having lung infiltrates ... Read more >>

Cureus (Cureus)
[2020, 12(9):e10268]

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Clinically Verified Hybrid Deep Learning System for Retinal Ganglion Cells Aware Grading of Glaucomatous Progression.

Hina Raja, Taimur Hassan, Muhammad Usman Akram, Naoufel Werghi,

OBJECTIVE:Glaucoma is the second leading cause of blindness worldwide. Glaucomatous progression can be easily monitored by analyzing the degeneration of retinal ganglion cells (RGCs). Many researchers have screened glaucoma by measuring cup-to-disc ratios from fundus and optical coherence tomography scans. However, this paper presents a novel strategy that pays attention ... Read more >>

IEEE Trans Biomed Eng (IEEE transactions on bio-medical engineering)
[2020, PP:]

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Challenges for biosimilars: focus on rheumatoid arthritis.

Muhammad Safwan Akram, Neelam Pery, Lucy Butler, Muhammad Imtiaz Shafiq, Nayab Batool, Muhammad Fayyaz Ur Rehman, Luke G Grahame-Dunn, Ali K Yetisen,

Healthcare systems worldwide are struggling to find ways to fund the cost of innovative treatments such as gene therapies, regenerative medicine, and monoclonal antibodies (mAbs). As the world's best known mAbs are close to facing patent expirations, the biosimilars market is poised to grow with the hope of bringing prices ... Read more >>

Crit Rev Biotechnol (Critical reviews in biotechnology)
[2020, :1-33]

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The Diagnostic Utility and Clinical Implications of Bronchoalveolar Lavage in Cancer Patients With Febrile Neutropenia and Lung Infiltrates

Alexander Muacevic, John R Adler, Usman Khalid, Muhammad J Akram, Faheem M Butt, Mohammad B Ashraf, Faheem Khan,

Introduction Febrile neutropenia (FN) is a dreaded complication of cancer chemotherapy and frequently associated with respiratory infections. Flexible bronchoscopy (FB) serves as a useful diagnostic tool in this regard. Objective To determine the diagnostic yield, safety and clinical implications of bronchoalveolar lavage (BAL) in cancer patients with FN, having lung infiltrates ... Read more >>

Cureus (Cureus)
[0, 12(9):]

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CuO Hollow Cubic Caves Wrapped with Biogenic N-Rich Graphitic C for Simultaneous Monitoring of Uric Acid and Xanthine.

Khizer Hayat, Aqsa Munawar, Anam Zulfiqar, Mahmood Hassan Akhtar, Hafiz Badaruddin Ahmad, Zahid Shafiq, Muhammad Akram, Awais Siddique Saleemi, Naeem Akhtar,

Herein, we synthesized hollow cubic caves of CuO (HC) and wrapped it with N-rich graphitic C (NC), derived from a novel biogenic mixture composed of dopamine (DA) and purine. The synthesized NC wrapped HC ([email protected]) sensor shows enhanced electrocatalytic efficacy compared to unwrapped CuO with shapes including HC, sponge (SP), ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2020, 12(42):47320-47329]

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Indications and clinical outcomes of fully covered self-expandable metallic tracheobronchial stents in patients with malignant airway diseases.

Muhammad Junaid Akram, Usman Khalid, Muhammad Abu Bakar, Mohammad Bilal Ashraf, Faheem Mehmood Butt, Faheem Khan,

BACKGROUND:Airway stenting is an efficacious approach in management of malignant airway disease (MAD) with improvement in survival outcome. OBJECTIVE:To determine the indications and long-term clinical outcomes of tracheobronchial stenting in patients with MAD. METHODS:A cross-sectional review of 51 patients who underwent airway stenting from June 2011 to June 2019 was ... Read more >>

Expert Rev Respir Med (Expert review of respiratory medicine)
[2020, 14(11):1173-1181]

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Cross Sectional Survey of Pakistani Muslims Coping Health Anxiety through Religiosity during COVID-19 Pandemic

Qaisar Khalid Mahmood, Malik Muhammad Sohail, Muhammad Babar Akram,

Abstract This study aims to investigate the role of religiosity in coping with health anxiety during the outbreak of COVID-19, a deadliest pandemic of century which is still affecting billions of lives globally. Using online survey method, the researchers collected the data from 408 Pakistani Muslim respondents. Health anxiety and ... Read more >>

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Phytochemical constituents, biological activities, and health-promoting effects of the genus Origanum.

Mehdi Sharifi-Rad, Yakup Berkay Yılmaz, Gizem Antika, Bahare Salehi, Tugba Boyunegmez Tumer, Chidambaram Kulandaisamy Venil, Gitishree Das, Jayanta Kumar Patra, Natallia Karazhan, Muhammad Akram, Mehwish Iqbal, Muhammad Imran, Surjit Sen, Krishnendu Acharya, Abhijit Dey, Javad Sharifi-Rad,

Origanum species are mostly distributed around the Mediterranean, Euro-Siberian, and Iran-Siberian regions. Since time immemorial, the genus has popularly been used in Southern Europe, as well as on the American continent as a spice now known all over the world under the name "oregano" or "pizza-spice." Origanum plants are also ... Read more >>

Phytother Res (Phytotherapy research : PTR)
[2020, :]

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Vicia plants-A comprehensive review on chemical composition and phytopharmacology.

Bahare Salehi, Ibrahim M Abu-Reidah, Farukh Sharopov, Natallia Karazhan, Javad Sharifi-Rad, Muhammad Akram, Muhammad Daniyal, Fahad Said Khan, Wafa Abbaass, Rida Zainab, Katya Carbone, Nouran M Fahmy, Eman Al-Sayed, Mohamed El-Shazly, Massimo Lucarini, Alessandra Durazzo, Antonello Santini, Miquel Martorell, Raffaele Pezzani,

The plants belonging to the genus Vicia are of great interest as a source of many bioactive compounds and micronutrients. A snapshot of their cultivation, habitat, main components, from which essential oils can be obtained, is given. The traditional medicinal uses of Vicia plants are also reported, as well as ... Read more >>

Phytother Res (Phytotherapy research : PTR)
[2020, :]

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Hantavirus diseases pathophysiology, their diagnostic strategies and therapeutic approaches: A review.

Naveed Munir, Muhammad Jahangeer, Shoukat Hussain, Zahed Mahmood, Mehvish Ashiq, Fatima Ehsan, Muhammad Akram, Syed Muhammad Ali Shah, Muhammad Riaz, Aneezah Sana,

Hantaviruses are enveloped negative (-) single-stranded RNA viruses belongs to Hantaviridae family, hosted by small rodents and entering into the human body through inhalation, causing haemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) also known as hantavirus cardiopulmonary syndrome (HCPS). Hantaviruses infect approximately more than 200 000 people ... Read more >>

Clin Exp Pharmacol Physiol (Clinical and experimental pharmacology & physiology)
[2020, :]

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Backward and Hopf bifurcation analysis of an SEIRS COVID-19 epidemic model with saturated incidence and saturated treatment response

David Adeyemi Oluyori, Ángel Pérez, Alexander Okhuese Victor, Muhammad Akram,

In this work, we further the investigation of an SEIRS model to study the dynamics of the Coronavirus Disease 2019 pandemic. We derive the basic reproduction number R 0 and study the local stability of the disease-free and endemic states. Since the condition R 0 < 1 for our model ... Read more >>

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Knowledge, Attitude, and Practices of Community Pharmacists on Antibiotic Resistance and Antimicrobial Stewardship in Lusaka, Zambia

Steward Mudenda, Mutinta Hankombo, Zikria Saleem, Mohammad Jaffar Sadiq, Michelo Banda, Derick Munkombwe, Chiluba Mwila, Maisa Kasanga, Annie Chibwe Zulu, Jimmy Mapenzi Hangoma, Webrod Mufwambi, Lungwani Tyson Muungo, Ronald Mutati Kampamba, Andrew Munkuli Bambala, Noor Mohammed Abdulrahman, Muhammad Akram, John Bwalya Muma,

Antibiotic resistance is among the major threats to global health. Due to limited information on the subject matter in Zambia, we assessed the knowledge, attitude, and practices of community pharmacists on antibiotic resistance and antimicrobial stewardship. We conducted a descriptive cross-sectional study among 144 randomly selected community pharmacists through a ... Read more >>

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Antihypertensive and Antihyperlipidemic Activity of Aqueous Methanolic Extract of Rauwolfia Serpentina in Albino Rats.

Syed Muhammad Ali Shah, Syed Ali Raza Naqvi, Naveed Munir, Sohaib Zafar, Muhammad Akram, Jaweria Nisar,

Rauwolfia serpentina has a wide range of therapeutic effects so this study was planned to explore the antihypertensive and antihyperlipidemic therapeutic responses of R serpentina doses using albino rats by measuring the blood pressure, biochemical parameters, and histological architecture of liver and kidney tissues. Thirty albino rats were divided into ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2020, 18(3):1559325820942077]

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Convergent Variations in the Leaf Traits of Desert Plants.

Muhammad Adnan Akram, Xiaoting Wang, Weigang Hu, Junlan Xiong, Yahui Zhang, Yan Deng, Jinzhi Ran, Jianming Deng,

Convergence is commonly caused by environmental filtering, severe climatic conditions and local disturbance. The basic aim of the present study was to understand the pattern of leaf traits across diverse desert plant species in a common garden, in addition to determining the effect of plant life forms (PLF), such as ... Read more >>

Plants (Basel) (Plants (Basel, Switzerland))
[2020, 9(8):]

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Polymer matrix: A good substrate material for oxygen probes used in pressure sensitive paints.

Muhammad Akram, Mahmood Hassan Akhtar, Muhammad Irfan, Yanqing Tian,

Over the past few years, surface pressure measurement has fundamental importance in many areas, particularly, aerodynamic research. Conventional methods involve pressure taps, but due to the nature of these pressure taps, only pressure information of isolated points on model surface is available, which limit their applications in aerodynamics studies. Recently ... Read more >>

Adv Colloid Interface Sci (Advances in colloid and interface science)
[2020, 283:102240]

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Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Of Mediastinal And Hilar Lymph Nodes- Five Years Of Experience At A Cancer Setting Hospital In Pakistan.

Usman Khalid, Muhammad Junaid Akram, Faheem Mehmood Butt, Mohammad Bilal Ashraf, Faheem Khan,

BACKGROUND:Endobronchial Ultrasound (EBUS) guided Transbronchial needle aspiration (TBNA) offers a minimally invasive diagnostic tool for mediastinal lymphadenopathy (ML). This study is done with the objective to determine the diagnostic utility of EBUS TBNA for ML in cancer and non-cancer patients. METHODS:This cross-sectional study, in which data was collected retrospectively included ... Read more >>

J Ayub Med Coll Abbottabad (Journal of Ayub Medical College, Abbottabad : JAMC)
[2020, 32(3):310-317]

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Indications and clinical outcomes of indwelling pleural catheter placement in patients with malignant pleural effusion in a cancer setting hospital.

Muhammad Junaid Akram, Usman Khalid, Muhammad Abu Bakar, Faheem Mahmood Butt, Mohammad Bilal Ashraf, Faheem Khan,

BACKGROUND:The placement of indwelling pleural catheters (IPC) is an effective outpatient approach for the management of malignant pleural effusions (MPE). AIMS:The indications and outcome of IPC in patients with MPE. Risk stratifications, prevention and management of IPC-related complications. METHODS:We retrospectively reviewed the clinical data of patients with MPE who underwent ... Read more >>

Clin Respir J (The clinical respiratory journal)
[2020, :]

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Neurotransmission cognitive theory: A novel approach for non-invasive brain stimulation using mechanical vibrations for the rehabilitation of neurological patients.

Aliya A Khan, Shahbaz K Ranjha, Muhammad U Akram, Sajid G Khawaja, Arslan Shaukat,

Patients suffering from neurological disorders require not only the treatment but also the rehabilitation to have their productive role in society. With the advent of modern technology and neuroscience techniques, different treatments are proposed and tested clinically. We propose a therapeutic and interventional noninvasive brain stimulation method that applies mechanical ... Read more >>

Med Hypotheses (Medical hypotheses)
[2020, 143:110078]

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TiO2 Mesocrystals Processed at Low Temperature as the Electron-Transport Material in Perovskite Solar Cells.

Minghuang Guo, Deli Shen, Yafeng Li, Muhammad Aftab Akram, Mingdeng Wei, Mingdeng Wei,

TiO2 is the most widely used material for preparing the electron-transporting layer (ETL) in perovskite solar cells (PSCs). However, it requires a high-temperature sintering process. Moreover, the intrinsic defects and low electron mobility of TiO2 ETLs cause instability and hysteresis effects in PSCs. In this study, a mesoporous film composed ... Read more >>

ChemSusChem (ChemSusChem)
[2020, :]

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Inanimate surfaces as potential source of 2019-nCoV spread and their disinfection with biocidal agents.

Muhammad Zeeshan Akram,

The WHO has declared COVID-19 illness a global health concern which is caused by 2019-nCoV, causing severe respiratory tract infections in humans. Transmissibility among individual to individual have been reported through droplets and probably also via contaminated surfaces and hands. Human coronaviruses can persist on inanimate surfaces such as plastic, ... Read more >>

(Virusdisease)
[2020, 31(2):94-96]

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