Full Text Journal Articles by
Author Muhammad Ajmal

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Editorial: Management of cardiovascular risk factors and other comorbidities in chronic kidney disease.

Sehrish Ali, Muhammad S Ajmal, Sankar D Navaneethan,

Curr. Opin. Nephrol. Hypertens. (Current opinion in nephrology and hypertension)
[2020, 29(5):453-456]

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Modeling smallholder livestock herders' intentions to adopt climate smart practices: An extended theory of planned behavior.

Muhammad Faisal, Xia Chunping, Shoaib Akhtar, Muhammad Haseeb Raza, Muhammad Tariq Iqbal Khan, Muhammad Arslan Ajmal,

Climate change is persistently causing adverse effects to the agriculture sector of developing countries, specifically in Asia. Pakistan is no exception to this effect and is ranked among the top 10 countries, which are most vulnerable to climate change. A huge upcoming challenge is to sustain an equilibrium among production ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2020, 27(31):39105-39122]

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Targeted drug delivery systems: synthesis and in-vitro bioactivity and apoptosis studies of gemcitabine-carbon dots conjugates.

Uzma Yunus, Muhammad Ahsan Zulfiqar, Muhammad Ajmal, Moazzam Hussain Bhatti, Gul-E-Saba Chaudhry, Tengku Sifzizul Tengku Muhammad, Yeong Yik Sung,

Gemcitabine is used to treat various cancers like breast, pancreatic, non-small lung carcinoma, ovarian, bladder and cervical cancers. Gemcitabine (GEM), however, has the problems of non-selectivity. Water-soluble, fluorescent and mono-dispersed carbon dots (CDs) were fabricated using sucrose by ultrasonic method. CDs were further conjugated with GEM through amide linkage. The ... Read more >>

Biomed Mater (Biomedical materials (Bristol, England))
[2020, :]

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Chronic Kidney Disease and Acute Kidney Injury Outcomes Post Left Ventricular Assist Device Implant.

Muhammad S Ajmal, Umang M Parikh, Harveen Lamba, Carl Walther,

Introduction Left ventricular assist devices (LVAD) are used as a bridge to heart transplant or destination therapy for patients with the New York Heart Association (NYHA) class 3 or 4 heart failure. Acute kidney injury (AKI) or need for renal replacement therapy (RRT) post-LVAD implant can lead to poor outcomes. ... Read more >>

Cureus (Cureus)
[2020, 12(4):e7725]

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Excitation-Emission Synchronization-Mediated Directional Fluorescence: Insight into Plasmon-Coupled Emission at Vibrational Resolution.

Yan Zhao, Yi-Hong Liu, Shuo-Hui Cao, Muhammad Ajmal, Yan-Yun Zhai, Xiao-Hui Pan, Min Chen, Yao-Qun Li,

Light-matter interactions have always been a fundamentally significant topic that has attracted much attention. It is important to reveal a fluorophore-plasmon interaction on the nanoscale. However, as a powerful investigative tool, fluorescence spectroscopy still suffers from a limited spectral resolution and the susceptibility to interfering substances. In this work, excitation-emission ... Read more >>

J Phys Chem Lett (The journal of physical chemistry letters)
[2020, 11(7):2701-2707]

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Atrial Septal Defect with Eisenmenger Syndrome: A Rare Presentation.

Arnold Nongmoh Forlemu, Muhammad Ajmal, Mehrdad Saririan,

Atrial septal defects (ASDs) are common congenital heart defects (CHD). The clinical course in patients without closure of the ASD is associated with significant morbidity and mortality in advanced age. A small percentage of patients may develop pulmonary arterial hypertension (PAH) due to left to right shunting that impacts morbidity ... Read more >>

Case Rep Cardiol (Case reports in cardiology)
[2020, 2020:8681761]

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Left Atrial Appendage Closure in Patients With Intracranial Hemorrhage and Nonvalvular Atrial Fibrillation.

Muhammad Ajmal, Hursh Naik, Abraham Kocheril,

BACKGROUND:Left atrial appendage (LAA) closure is primarily performed in patients who have contraindications to anticoagulants. However, anticoagulants are recommended for the first few weeks after LAA closure to prevent the device related thrombus. Purpose of this study was to evaluate if short term use of anticoagulant is safe and effective ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2020, 29(4):104685]

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Traditional Medications Mixed with Ethylene Glycol in a Nigerian Patient on Hemodialysis.

Muhammad S Ajmal, Adebowale Awosika-Olumo, Rajeev Raghavan,

Unregulated traditional medications and their solvents are nephrotoxic. We present a case of a 49-year-old Nigerian male with a 10-year history of diabetes mellitus and hypertension who was ingesting a traditional, herbal medication as an aphrodisiac for erectile dysfunction. He had a rapid decline in kidney function over a period of one ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6950]

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Design, Synthesis, and Targeted Delivery of Fluorescent 1,2,4-Triazole-Peptide Conjugates to Pediatric Brain Tumor Cells.

Muhammad Ajmal, Uzma Yunus, Regina M Graham, Roger M Leblanc,

Most of the chemotherapeutics and drug-delivery models pose serious health problems and several undesirable side effects due to nonspecificity, lack of proper targeting system, and their large sizes. The rational design and synthesis of target-specific chemotherapeutics are highly important. This research work is focused on the rational design, synthesis, and ... Read more >>

ACS Omega (ACS omega)
[2019, 4(27):22280-22291]

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Synthesis and molecular characterization of chitosan/starch blends based polyurethanes.

Muhammad Asif Javaid, Khalid Mahmood Zia, Kashif Zafar, Muhammad Kaleem Khosa, Nadia Akram, Muhammad Ajmal, Muhammad Imran, Muhammad Naeem Iqbal,

Starch/chitosan modified polyurethanes (PUs) were synthesized by step growth polymerization reaction between -NCO terminated prepolymer and chain extenders (1,4-Butanediol/starch/chitosan). Isophorone diisocyanate (IPDI) was reacted with hydroxyl-terminated polybutadiene (HTPB) to synthesize prepolymer and was further reacted with different moles ratio of starch/chitosan to produced five samples of polyurethane (PU). These samples ... Read more >>

Int. J. Biol. Macromol. (International journal of biological macromolecules)
[2020, 146:243-252]

Cited: 1 time

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Changes in fatty acids composition, antioxidant potential and induction period of UHT-treated tea whitener, milk and dairy drink.

Muhammad Ajmal, Muhammad Nadeem, Muhammad Imran, Zarina Mushtaq, Muhammad Haseeb Ahmad, Muhammad Tayyab, Muhammad Kamran Khan, Nabila Gulzar,

BACKGROUND:In developing and developed countries, several versions of safe and shelf-stable Ultra High Temperature, UHT-treated products are manufactured. Terminologies and formulations of UHT-treated tea whitener, milk and dairy drink considerably vary. Comprehensive studies have been performed on UHT-treated milk; however, fatty acids compositional changes and oxidation status of UHT-treated tea ... Read more >>

Lipids Health Dis (Lipids in health and disease)
[2019, 18(1):213]

Cited: 1 time

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Publisher Correction: Combining Biomarkers with EMR Data to Identify Patients in Different Phases of Sepsis.

Ishan Taneja, Bobby Reddy, Gregory Damhorst, Sihai Dave Zhao, Umer Hassan, Zachary Price, Tor Jensen, Tanmay Ghonge, Manish Patel, Samuel Wachspress, Jackson Winter, Michael Rappleye, Gillian Smith, Ryan Healey, Muhammad Ajmal, Muhammad Khan, Jay Patel, Harsh Rawal, Raiya Sarwar, Sumeet Soni, Syed Anwaruddin, Benjamin Davis, James Kumar, Karen White, Rashid Bashir, Ruoqing Zhu,

An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):17419]

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Acute Device-Related Thrombus after Watchman Device Implant.

Muhammad Ajmal, Vijendra Swarup,

Atrial fibrillation is characterized by irregularly irregular heart rhythm with an increased morbidity and mortality. It is associated with an increased risk of thromboembolism due to formation of blood clot in the left atrium. Most of these blood clots are formed in the left atrial appendage. The risk of blood ... Read more >>

(Case reports in cardiology)
[2019, 2019:8397561]

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Advancements in electrochemical sensing of hydrogen peroxide, glucose and dopamine by using 2D nanoarchitectures of layered double hydroxides or metal dichalcogenides. A review.

Ayesha Aziz, Muhammad Asif, Ghazala Ashraf, Muhammad Azeem, Irfan Majeed, Muhammad Ajmal, Junlei Wang, Hongfang Liu,

This review (with 105 references) describes the progress that has been made in the past few years in the use of 2D nanoarchitectures in electrochemical sensors for the clinically highly significant parameters hydrogen peroxide, glucose and dopamine. Following an introduction into the field, we summarize the improvements in electrochemical sensors that ... Read more >>

Mikrochim Acta (Mikrochimica acta)
[2019, 186(10):671]

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Association of IGF1 and VEGFA polymorphisms with diabetic retinopathy in Pakistani population.

Netasha Khan, Andrew D Paterson, Delnaz Roshandel, Ali Raza, Muhammad Ajmal, Nadia K Waheed, Maleeha Azam, Raheel Qamar,

AIMS:The incidence of microvascular complications, including diabetic retinopathy (DR), increases with duration of type 2 diabetes (T2D). Meta-GWAS have reported numerous single-nucleotide polymorphisms (SNPs) associated with T2D; however, no loci, achieving genome-wide significance has been reported for DR. Vascular endothelial growth factor A (VEGFA) and insulin-like growth factor 1 (IGF1) ... Read more >>

Acta Diabetol (Acta diabetologica)
[2020, 57(2):237-245]

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Design, synthesis, in-silico study and anticancer potential of novel n-4- piperazinyl-ciprofloxacin-aniline hybrids.

Rabia Akhtar, Ameer Fawad Zahoor, Azhar Rasul, Matloob Ahmad, Muhammad Naveed Anjum, Muhammad Ajmal, Zohaib Raza,

Synthesis and characterization of novel structural hybrids of ciprofloxacin linked with a variety of anilides have been described in this paper. Antitumor activity of these derivatives was assessed against liver cell line (Huh-7) using MTT assay. Among the synthesized derivatives, compound 6a inhibited the growth of tumor cells by displaying ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2019, 32(5(Supplementary)):2215-2222]

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Genetic and Molecular Control of Floral Organ Identity in Cereals.

Zulfiqar Ali, Qasim Raza, Rana Muhammad Atif, Usman Aslam, Muhammad Ajmal, Gyuhwa Chung,

Grasses represent a major family of monocots comprising mostly cereals. When compared to their eudicot counterparts, cereals show a remarkable morphological diversity. Understanding the molecular basis of floral organ identity and inflorescence development is crucial to gain insight into the grain development for yield improvement purposes in cereals, however, the ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 20(11):]

Cited: 1 time

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Implementation of public health genomics in Pakistan.

Moeen Riaz, Jane Tiller, Muhammad Ajmal, Maleeha Azam, Raheel Qamar, Paul Lacaze,

There has been considerable recent progress in the implementation of public health genomics policy throughout the developed world. However, in the developing world, genetic services still remain limited, or unavailable to most. Here, we discuss challenges and opportunities related to the implementation of public health genomics in developing countries. We ... Read more >>

Eur J Hum Genet (European journal of human genetics : EJHG)
[2019, 27(10):1485-1492]

Cited: 1 time

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Reversing current rectification to improve DNA-sensing sensitivity in conical nanopores.

Xiu-Hong Cai, Shuo-Hui Cao, Sheng-Lin Cai, Yuan-Yi Wu, Muhammad Ajmal, Yao-Qun Li,

Herein, we report the ultrasensitive DNA detection through designing an elegant nanopore biosensor as the first case to realize the reversal of current rectification direction for sensing. Attributed to the unique asymmetric structure, the glass conical nanopore exhibits the sensitive response to the surface charge, which can be facilely monitored ... Read more >>

Electrophoresis (Electrophoresis)
[2019, 40(16-17):2098-2103]

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Antioxidant properties of Milk and dairy products: a comprehensive review of the current knowledge.

Imran Taj Khan, Muhammad Nadeem, Muhammad Imran, Rahman Ullah, Muhammad Ajmal, Muhammad Hayat Jaspal,

Milk and dairy products are integral part of human nutrition and they are considered as the carriers of higher biological value proteins, calcium, essential fatty acids, amino acids, fat, water soluble vitamins and several bioactive compounds that are highly significant for several biochemical and physiological functions. In recent years, foods ... Read more >>

Lipids Health Dis (Lipids in health and disease)
[2019, 18(1):41]

Cited: 9 times

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Superlattice stacking by hybridizing layered double hydroxide nanosheets with layers of reduced graphene oxide for electrochemical simultaneous determination of dopamine, uric acid and ascorbic acid.

Muhammad Asif, Ayesha Aziz, Haitao Wang, Zhengyun Wang, Wei Wang, Muhammad Ajmal, Fei Xiao, Xuedong Chen, Hongfang Liu,

A self-assembled periodic superlattice material was obtained by integrating positively charged semiconductive sheets of a Zn-NiAl layered double hydroxide (LDH) and negatively charged layers of reduced graphene oxide (rGO). The material was used to modify a glassy carbon electrode which then is shown to be a viable sensor for the ... Read more >>

Mikrochim Acta (Mikrochimica acta)
[2019, 186(2):61]

Cited: 6 times

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Facile synthesis of graphene oxide-silver nanocomposite for decontamination of water from multiple pollutants by adsorption, catalysis and antibacterial activity.

Hina Naeem, Muhammad Ajmal, Raheela Beenish Qureshi, Sedra Tul Muntha, Muhammad Farooq, Muhammad Siddiq,

Here in, we presented a facile one-step method for the synthesis of Graphene oxide-silver (GO-Ag) nanocomposite and its applications as a sorbent for the elimination of some toxic pollutants from aqueous medium, as an efficient catalyst in the individual as well as simultaneous reduction reactions of multiple compounds, and as ... Read more >>

J. Environ. Manage. (Journal of environmental management)
[2019, 230:199-211]

Cited: 3 times

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Lipid compositional changes and oxidation status of ultra-high temperature treated Milk.

Muhammad Ajmal, Muhammad Nadeem, Muhammad Imran, Muhammad Junaid,

BACKGROUND:Milk fat is one of the complex fat and most sensitive biochemical compounds towards auto-oxidation. To enhance the shelf life, milk is subjected to Ultra-high Temperature (UHT) treatment followed by aseptic packaging. During the storage, several chemical and biochemical changes take place in lipid fraction of UHT milk. In current ... Read more >>

Lipids Health Dis (Lipids in health and disease)
[2018, 17(1):227]

Cited: 3 times

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Impact of immediate and delayed chilling of raw milk on chemical changes in lipid fraction of pasteurized milk.

Muhammad Ajmal, Muhammad Nadeem, Muhammad Imran, Muhammad Abid, Maryam Batool, Imran Taj Khan, Nabila Gulzar, Muhammad Tayyab,

BACKGROUND:In many developing countries, milk chilling facilities are not available on the farm where milk is produced, rather these are located at the distance of 10-12 km. After milking, it takes about 2-3 h to reach milk to the chilling facilities. The milk is then chilled and transported to the milk processing ... Read more >>

Lipids Health Dis (Lipids in health and disease)
[2018, 17(1):190]

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Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene.

Muhammad Idrees, Abdul Rauf Siddiq, Muhammad Ajmal, Muhammad Akram, Rana Rehan Khalid, Alamdar Hussain, Raheel Qamar, Habib Bokhari,

Paraoxonase 1 (PON1) is a serum enzyme associated with high density lipoprotein (HDL) regulation through its paraoxonase and arylesterase activity. PON1 inhibits the oxidation of HDL and low density lipoprotein (LDL), and is involved in the pathogenesis of a variety of diseases including atherosclerosis. Conversely, mutations in the low density ... Read more >>

(Genetics and molecular biology)
[2018, 41(3):570-577]

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