Full Text Journal Articles by
Author Mudar Zand Irani

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Prevalence, symptoms and risk factor profile of rumination syndrome and functional dyspepsia: a population-based study.

Mudar Zand Irani, Michael P Jones, Magnus Halland, Linda Herrick, Rok Seon Choung, Yuri A Saito Loftus, Marjorie M Walker, Joseph A Murray, Nicholas J Talley,

<h4>Background</h4>Rumination syndrome is a functional gastroduodenal disorder characterised by effortless regurgitation of recently ingested food. Emerging evidence reports duodenal eosinophilic inflammation in a subset, suggesting a shared pathophysiology with functional dyspepsia (FD).<h4>Aim</h4>To assess the clinical features of rumination syndrome and FD in a community-based study.<h4>Methods</h4>We mailed a survey assessing gastrointestinal ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, :]

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Neutrophils, eosinophils, and intraepithelial lymphocytes in the squamous esophagus in subjects with and without gastroesophageal reflux symptoms.

Mudar Zand Irani, Nicholas J Talley, Jukka Ronkainen, Pertti Aro, Anna Andreasson, Lars Agreus, Michael Vieth, Mike P Jones, Marjorie M Walker,

Whilst intraepithelial lymphocytes (IELs) are considered normal within the distal esophageal mucosa, they have an increasingly recognised role in the pathogenesis of reflux esophagitis, and IEL quantification establishes the diagnosis of lymphocytic esophagitis. Knowledge regarding the upper limit of a normal IEL count in health is lacking. We studied 117 ... Read more >>

Hum Pathol (Human pathology)
[2021, 115:112-122]

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