Full Text Journal Articles by
Author Moosa Khan

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Influence of single nucleotide polymorphism of LAT1 on therapeutic response to gabapentinoids in Pakistani patients with neuropathic pain.

Abida Shaheen, Syed Mahboob Alam, Fahad Azam, Moosa Khan, Salman Ahmad Saleem, Afrose Liaquat, Sana Mumtaz,

Gabapentinoids are substrate of L-type amino acid transporter1 (LAT1) for distribution across the blood-brain barrier. The present study aimed to evaluate the effect of LAT1 rs4240803 genetic polymorphism on the clinical efficacy and tolerability of gabapentinoids in Pakistani patients with neuropathic pain. Three hundred and ninety-two patients were recruited, genotyped ... Read more >>

Basic Clin Pharmacol Toxicol (Basic & clinical pharmacology & toxicology)
[2020, :]

Cited: 0 times

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Clinical efficacy and tolerability of Gabapentinoids with current prescription patterns in patients with Neuropathic pain.

Abida Shaheen, Syed Mahboob Alam, Arsalan Ahmad, Moosa Khan,

Objective:To investigate the current dosing regimens of gabapentinoids in Pakistani patients with neuropathic pain and to compare their clinical efficacy and tolerability in terms of pain relief and adverse effects using difference in pain score as a treatment outcome. Methods:This observational, prospective study was conducted in 320 patients with neuropathic ... Read more >>

Pak J Med Sci (Pakistan journal of medical sciences)
[2019, 35(6):1505-1510]

Cited: 0 times

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Clinical Efficacy and Safety of Tacrolimus in Pakistani Living Donor Liver Transplant Recipients.

Fahad Azam, Moosa Khan, Abu Bakar Hafeez Bhatti, Faisal Saud Dar, Arsalan Ahmad, Nismat Javed,

OBJECTIVE:To evaluate the association between tacrolimus trough levels and dosage in Pakistani patients undergoing live donor liver transplantation (LDLT), and the efficacy and adverse effects at different tacrolimus trough levels and dosages. STUDY DESIGN:An observational study. PLACE AND DURATION OF STUDY:Shifa International Hospital, Shifa Tameer-e-Millat University, Islamabad and Basic Medical ... Read more >>

J Coll Physicians Surg Pak (Journal of the College of Physicians and Surgeons--Pakistan : JCPSP)
[2019, 29(11):1048-1052]

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Comparison of Bioelectrical Impedance and Navy Seal Formula to Measure Body Composition in Medical Students.

Abida Shaheen, Nismat Javed, Fahad Azam, Afrose Liaquat, Moosa Khan, Syed Mahboob Alam, Sana Mumtaz,

Objectives There are many different ways to measure body composition and bioelectric impedance is one of the most popular methods to measure body ratios. The navy-seal formula is another simple way of measuring body fat ratio which takes into account simple variables such as gender, weight, height, waist, hip and ... Read more >>

Cureus (Cureus)
[2019, 11(5):e4723]

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Atorvastatin as an adjuvant with betamethasone valerate reduces disease severity and cardiovascular risks in Psoriasis.

Farah Asad, Moosa Khan, Fatima Rizvi,

Objectives:To evaluate the effect of Atorvastatin as an adjuvant with betamethasone valerate on disease severity and cardiovascular risks in chronic plaque type psoriatic patients. Methods:It is an interventional study conducted in Pharmacology Department of BMSI, JPMC with the collaboration of Dermatology Department of JPMC, Karachi. The duration of study was ... Read more >>

Pak J Med Sci (Pakistan journal of medical sciences)
[2017, 33(6):1507-1511]

Cited: 0 times

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The hepatoprotective role of Silymarin in isoniazid induced liver damage of rabbits.

Sarwat Jahan, Moosa Khan, Sana Imran, Mohammad Sair,

To evaluate the hepatoprotective role of Silymarin against isonicotinylhydrazine-induced hepatotoxicity in rabbit model.The experimental animal study was held at Jinnah Postgraduate Medical Centre, Karachi, from April to September 2013 and comprised rabbits weighing 1-1.5kgof either gender. The animals were divided randomly into equal groups: group I underwent liver function test ... Read more >>

J Pak Med Assoc (JPMA. The Journal of the Pakistan Medical Association)
[2015, 65(6):620-622]

Cited: 10 times

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The Epidemiology of Suicide Behaviors among the Countries of the Eastern Mediterranean Region of WHO: a Systematic Review.

Seyed Kazem Malakouti, Farnoush Davoudi, Saeed Khalid, Masoud Ahmadzad Asl, Murad Moosa Khan, Narges Alirezaei, Arash Mirabzadeh, Diego DeLeo,

This systematic review aimed to help better to understand the epidemiology of suicidal behaviors among Eastern Mediterranean Region (EMR) countries. The PubMed, EMR medex, Scopus, PsychInfo, ISI, and IMEMR were searched with no language limitation for papers on the epidemiology of suicidal behaviors in the general population, published up to ... Read more >>

Acta Med Iran (Acta medica Iranica)
[2015, 53(5):257-265]

Cited: 11 times

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Comparison of efficacy and safety of topiramate with gabapentin in migraine prophylaxis: randomized open label control trial.

Syeda Zain, Moosa Khan, Rafique Alam, Irfan Zafar, Shakil Ahmed,

OBJECTIVE: To compare the efficacy and safety of topiramate with gabapentin in the prophylaxis of migraine patients. METHODS: A 12-week randomised open label control trial was conducted at the Department of Pharmacology and Therapeutics, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre (JPMC), Karachi from January to March 2011 involving ... Read more >>

J Pak Med Assoc (JPMA. The Journal of the Pakistan Medical Association)
[2013, 63(1):3-7]

Cited: 9 times

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To study the efficacy of Losartan on urinary uric acid excretion in Thiazide induced hyperuricemic and hypertensive patients.

Moosa Khan, Rafeeq Alam Khan, Farida Islam, Jamil Laghari, Shah Nawaz Jamali,

The precise relationship of Hyperuricemia found in hypertensive patients is still obscure; this study is a urinary uric acid lowering intervention with Losartan in hypertensive patients induced by Thiazide diuretics. A number of pharmacological agents like loop diuretics, similarly low doses of aspirin (<3g daily) aggravate Hyperuricemia. The effect of ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2011, 24(4):583-587]

Cited: 5 times

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Assessment of efficacy and adverse effects of trazodone in the treatment of major depressive disorder.

Ali Gul Tunio, Moosa Khan, Dial Das, Ghulam Sarwar,

BACKGROUND: Major depressive disorder is a serious and disabling illness in the world and is common chronic and recurrent disorder. It is the fourth most important cause of worldwide loss in disability. METHODS: This was prospective and open-label study, study conducted in JPMC. Karachi, to evaluate the efficacy and adverse ... Read more >>

J Ayub Med Coll Abbottabad (Journal of Ayub Medical College, Abbottabad : JAMC)
[2010, 22(3):94-95]

Cited: 1 time

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Safety and efficacy of lodoxamide in vernal keratoconjunctivitis.

Dial Das, Moosa Khan, Ali Gul, Raffique Alam,

OBJECTIVE: To observe the safety and efficacy of topical Lodoxamide eye drops in patients with diagnosed vernal keratoconjunctivitis (VKC). METHODS: This study was conducted at Department of Pharmacology and Therapeutics, BMSI, JPMC, Karachi in collaboration with Department of Ophthalmology, JPMC, Karachi, from April to October, 2009. A total of forty ... Read more >>

J Pak Med Assoc (JPMA. The Journal of the Pakistan Medical Association)
[2011, 61(3):239-241]

Cited: 3 times

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Influence of sibutramine, orlistat and Ispaghula in reducing body weight and total body fat content in obese individuals.

Syed Asif J Kazmi, Moosa Khan, Ghulam Rasool Mashori, Azra Saleem, Naheed Akhtar, Ashraf Jahangeer,

BACKGROUND: The correlations between combined body fat parameters and risk factors of obesity explained a portion of the variation in the weight, BMI and waist circumference, the average number of categorical metabolic risk factors increases progressively with increasing total body fat content. There is currently no data available in which ... Read more >>

J Ayub Med Coll Abbottabad (Journal of Ayub Medical College, Abbottabad : JAMC)
[2009, 21(2):45-48]

Cited: 2 times

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