Nada H El-Dershaby, Soad A El-Hawash, Shaymaa E Kassab, Hoda G Dabees, Ahmed E Abdel Moneim, Ibrahim A Abdel Wahab, Mohammad M Abd-Alhaseeb, Mostafa M M El-Miligy,
A new series of co-drugs was designed based on hybridising the dihydropteroate synthase (DHPS) inhibitor sulphonamide scaffold with the COX-2 inhibitor salicylamide pharmacophore through biodegradable linkage to achieve compounds with synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme to enhance antibacterial activity for treatment of septicaemia. Compounds <b>5 b, 5j, ... Read more >>
J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2022, 37(1):1737-1751]
Cited: 0 times
Nihal M El Newehy, Mohammad M Abd-Alhaseeb, Gamal A Omran, Fathallah M Harraz, Eman Shawky,
The different parts of pomegranate fruit are considered a powerful mixture of bioactive compounds yet the peels and pulps of the fruits are usually discarded and considered as industrial waste. In this work, ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry (UPLC-QqQ-MS) was utilized for metabolomics analysis of different ... Read more >>
J Sci Food Agric (Journal of the science of food and agriculture)
[2022, :]
Cited: 0 times