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Author Mohammad Abufaraj

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Association between SARS-CoV-2 infection and disease severity among prostate cancer patients on androgen deprivation therapy: a systematic review and meta-analysis.

Reza Sari Motlagh, Mohammad Abufaraj, Pierre I Karakiewicz, Pawel Rajwa, Keiichiro Mori, Dong-Ho Mun, Shahrokh F Shariat,

<h4>Purpose</h4>Androgen-regulated enzymes such as the angiotensin-converting enzyme 2 (ACE2) and the transmembrane serine protease 2 (TMPRSS2) are involved in the SARS-CoV-2 infection process. The expression of TMPRSS2 and its fusion gene, which are increased in the epithelium of the human prostate gland during prostate carcinogenesis, are regulated by androgens. Our ... Read more >>

World J Urol (World journal of urology)
[2021, :]

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The Efficacy and Safety of Relugolix Compared with Degarelix in Advanced Prostate Cancer Patients: A Network Meta-analysis of Randomized Trials.

Reza Sari Motlagh, Mohammad Abufaraj, Keiichiro Mori, Abdulmajeed Aydh, Pawel Rajwa, Satoshi Katayama, Nico C Grossmann, Ekaterina Laukhtina, Hadi Mostafai, Benjamin Pradere, Fahad Quhal, Pierre I Karakiewicz, Dmitry V Enikeev, Shahrokh F Shariat,

<h4>Context</h4>Degarelix is associated with high rates of injection site reaction. The US Food and Drug Administration approved relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, for the treatment of advanced prostate cancer patients.<h4>Objective</h4>This systematic review and network meta-analysis aimed to compare the efficacy and safety of relugolix versus degarelix.<h4>Evidence acquisition</h4>A systematic ... Read more >>

Eur Urol Oncol (European urology oncology)
[2021, :]

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Prognostic value of the preoperative albumin-globulin ratio in patients with upper urinary tract urothelial carcinoma treated with radical nephroureterectomy: results from a large multicenter international collaboration.

Noriyoshi Miura, Keiichiro Mori, Ekaterina Laukhtina, Victor M Schuettfort, Mohammad Abufaraj, Jeremy Y C Teoh, Stefano Luzzago, Franziska Stolzenbach, Marina Deuker, Pierre I Karakiewicz, Alberto Briganti, Dmitry V Enikeev, Morgan Rouprêt, Vitaly Margulis, Piotr Chlosta, Peter Nyirady, Marek Babjuk, Shin Egawa, Takashi Saika, Shahrokh F Shariat,

<h4>Objective</h4>To assess the value of preoperative albumin to globulin ratio for predicting pathologic and oncological outcomes in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy in a large multi-institutional cohort.<h4>Materials and methods</h4>Preoperative albumin to globulin ratio was assessed in a multi-institutional cohort of 2492 patients. Logistic regression analyses ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(7):1149-1157]

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Prognostic value of the pre-operative serum albumin to globulin ratio in patients with non-metastatic prostate cancer undergoing radical prostatectomy.

Abdulmajeed Aydh, Keiichiro Mori, David D'Andrea, Reza Sari Motlagh, Mohammad Abufaraj, Benjamin Pradere, Hadi Mostafaei, Ekaterina Laukhtina, Fahad Quhal, Pierre I Karakiewicz, Stefano Luzzago, Alberto Briganti, Quoc-Dien Trinh, Mehdi Kardoust Parizi, Derya Tilki, Dmitry V Enikeev, Shahrokh F Shariat,

<h4>Purpose</h4>To evaluate the potential predictive value of the preoperative serum albumin to globulin ratio (AGR) for oncological outcomes in patients treated with radical prostatectomy (RP) for clinically non-metastatic prostate cancer (PCa).<h4>Methods</h4>Pre-operative AGR was assessed in a multi-institutional cohort of 6041 patients treated with RP. Logistic regression analyses were performed to ... Read more >>

Int J Clin Oncol (International journal of clinical oncology)
[2021, 26(9):1729-1735]

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Prognostic Impact of Preoperative Plasma Levels of Urokinase Plasminogen Activator Proteins on Disease Outcomes after Radical Cystectomy.

Victor M Schuettfort, Benjamin Pradere, David D'Andrea, Nico C Grossmann, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Michael Rink, Pierre I Karakiewicz, Reza Sari Motlagh, Satoshi Katayama, Yair Lotan, Douglas Scherr, Mohammad Abufaraj, Harun Fajkovica, Eva Compérat, Dmitry Enikeev, Shahrokh F Shariat,

<h4>Purpose</h4>We sought to validate the association of plasma levels of urokinase-type plasminogen activator (uPA), its soluble receptor (SuPAR) and its inhibitor (PAI-one) with oncologic outcomes in a large cohort of patients treated with radical cystectomy (RC) for urothelial carcinoma of the bladder (UCB).<h4>Materials and methods</h4>We collected preoperative blood samples from ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001936]

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Systemic therapies for metastatic hormone-sensitive prostate cancer: network meta-analysis.

Keiichiro Mori, Hadi Mostafaei, Reza Sari Motlagh, Benjamin Pradere, Fahad Quhal, Ekaterina Laukhtina, Victor M Schuettfort, Gero Kramer, Mohammad Abufaraj, Pierre I Karakiewicz, Takahiro Kimura, Shin Egawa, Shahrokh F Shariat,

<h4>Objectives</h4>To perform a systematic review and network meta-analysis to compare the efficacy and safety of currently available treatments for the management of metastatic hormone-sensitive prostate cancer (mHSPC), as there has been a paradigm shift with the use of next-generation androgen receptor inhibitors (ARIs) and docetaxel.<h4>Methods</h4>Multiple databases were searched for articles ... Read more >>

BJU Int (BJU international)
[2021, :]

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Novel transurethral resection technologies and training modalities in the management of nonmuscle invasive bladder cancer: a comprehensive review.

Victor M Schuettfort, Benjamin Pradere, Eva Compérat, Mohammad Abufaraj, Shahrokh F Shariat,

<h4>Purpose of review</h4>Conventional transurethral resection (TURBT) with tumor fragmentation is the primary step in the surgical treatment of nonmuscle invasive bladder cancer. Recently, new surgical techniques and training modalities have emerged with the aim to overcome short-comings of TURBT and improve oncologic outcomes. In this review, we provide a comprehensive ... Read more >>

Curr Opin Urol (Current opinion in urology)
[2021, 31(4):324-331]

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Incidence, risk factors and outcomes of urethral recurrence after radical cystectomy for bladder cancer: A systematic review and meta-analysis.

Ekaterina Laukhtina, Keiichiro Mori, David D Andrea, Marco Moschini, Mohammad Abufaraj, Francesco Soria, Andrea Mari, Wojciech Krajewski, Simone Albisinni, Jeremy Yuen-Chun Teoh, Fahad Quhal, Reza Sari Motlagh, Hadi Mostafaei, Satoshi Katayama, Nico С Grossmann, Pawel Rajwa, Dmitry Enikeev, Kristin Zimmermann, Harun Fajkovic, Petr Glybochko, Shahrokh F Shariat, Benjamin Pradere, ,

We aimed to conduct a systematic review and meta-analysis assessing the incidence and risk factors of urethral recurrence (UR) as well as summarizing data on survival outcomes in patients with UR after radical cystectomy (RC) for bladder cancer. The MEDLINE and EMBASE databases were searched in February 2021 for studies ... Read more >>

Urol Oncol (Urologic oncology)
[2021, :]

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Impact of the preoperative modified glasgow prognostic score on disease outcome after radical cystectomy for urothelial carcinoma of the bladder.

Victor M Schuettfort, Kilian Gust, David D'Andrea, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Michael Rink, Mohammad Abufaraj, Pierre I Karakiewicz, Stefano Luzzago, Morgan Rouprêt, Dmitry Enikeev, Kristin Zimmermann, Marina Deuker, Marco Moschini, Reza Sari Motlagh, Nico C Grossmann, Satoshi Katayama, Benjamin Pradere, Shahrokh F Shariat,

<h4>Background</h4>To investigate the predictive and prognostic value of the preoperative modified Glasgow Prognostic Score (mGPS) in patients with urothelial carcinoma of the bladder (UCB) treated with radical cystectomy (RC).<h4>Methods</h4>We conducted a retrospective analysis of an established multicenter database consisting of 4,335 patients who were treated with RC +/- adjuvant chemotherapy ... Read more >>

Minerva Urol Nephrol (Minerva urology and nephrology)
[2021, :]

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Accuracy of Frozen Section Analysis of Urethral and Ureteral Margins During Radical Cystectomy for Bladder Cancer: A Systematic Review and Diagnostic Meta-Analysis.

Ekaterina Laukhtina, Pawel Rajwa, Keiichiro Mori, Marco Moschini, David D'Andrea, Mohammad Abufaraj, Francesco Soria, Andrea Mari, Wojciech Krajewski, Simone Albisinni, Jeremy Yuen-Chun Teoh, Fahad Quhal, Reza Sari Motlagh, Hadi Mostafaei, Satoshi Katayama, Nico C Grossmann, Dmitry Enikeev, Kristin Zimmermann, Harun Fajkovic, Petr Glybochko, Shahrokh F Shariat, Benjamin Pradere, ,

<h4>Context</h4>The question of the ability of frozen section analysis (FSA) to accurately detect malignant pathology intraoperatively has been discussed for many decades.<h4>Objective</h4>We aimed to conduct a systematic review and meta-analysis assessing the diagnostic estimates of FSA of the urethral and ureteral margins in patients treated with radical cystectomy (RC) for ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Prognostic Impact of Different Gleason Patterns on Biopsy Within Grade Group 4 Prostate Cancer.

Keiichiro Mori, Vidit Sharma, Eva M Comperat, Shun Sato, Ekaterina Laukhtina, Victor M Schuettfort, Benjamin Pradere, Reza Sari Motlagh, Hadi Mostafaei, Fahad Quhal, Mehdi Kardoust Parizi, Mohammad Abufaraj, Pierre I Karakiewicz, Shin Egawa, Derya Tilki, Stephen A Boorjian, Shahrokh F Shariat,

<h4>Background</h4>Grade group (GG) 4 prostate cancer (PC) is considered a single entity; however, there are questions regarding prognostic heterogeneity. This study assessed the prognostic differences among various Gleason scores (GSs) classified as GG 4 PC on biopsy before radical prostatectomy (RP).<h4>Methods</h4>We conducted a multicenter retrospective study, and a total of ... Read more >>

Ann Surg Oncol (Annals of surgical oncology)
[2021, :]

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Oncologic impact of delaying radical prostatectomy in men with intermediate- and high-risk prostate cancer: a systematic review.

Ekaterina Laukhtina, Reza Sari Motlagh, Keiichiro Mori, Fahad Quhal, Victor M Schuettfort, Hadi Mostafaei, Satoshi Katayama, Nico C Grossmann, Guillaume Ploussard, Pierre I Karakiewicz, Alberto Briganti, Mohammad Abufaraj, Dmitry Enikeev, Benjamin Pradere, Shahrokh F Shariat,

<h4>Purpose</h4>To summarize the available evidence on the survival and pathologic outcomes after deferred radical prostatectomy (RP) in men with intermediate- and high-risk prostate cancer (PCa).<h4>Methods</h4>The PubMed database and Web of Science were searched in November 2020 according to the PRISMA statement. Studies were deemed eligible if they reported the survival ... Read more >>

World J Urol (World journal of urology)
[2021, :]

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Current application of the enhanced recovery after surgery protocol for patients undergoing radical cystectomy: lessons learned from European excellence centers.

Simone Albisinni, Marco Moschini, Ettore Di Trapani, Francesco Soria, Andrea Mari, Atiqullah Aziz, Jeremy Teoh, Ekaterina Laukhtina, Keiichiro Mori, David D'Andrea, Diego M Carrion, Wojciech Krajewski, Mohammad Abufaraj, Alessia Cimadamore, Wei Shen Tan, Ronan Flippot, Jonathan Khalifa, Kimberly Gonsette, Benjamin Pradere, ,

<h4>Purpose</h4>There is no consensus on which items of Enhanced Recovery After Surgery (ERAS) should and should not be implemented in radical cystectomy (RC). The aim of this study is to report current practices across European high-volume RC centers involved in ERAS.<h4>Methods</h4>Based on the recommendations of the ERAS society, we developed ... Read more >>

World J Urol (World journal of urology)
[2021, :]

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The combinatorial use of propofol-fentanyl-ketamine for sedoanalgesia in patients undergoing urological procedures.

Abdelkarim S Aloweidi, Sami A Abu-Halaweh, Ghazi M Al-Edwan, Saddam H Al Demour, Laith T Abu Mahfuz, Osama N Noubani, Mohammad M Al Rwaidi, Isam K Bsisu, Mohammad M Abufaraj,

<h4>Objectives</h4>To compare sedoanalgesia achieved using propofol-fentanyl-ketamine (PFK) combination with general anesthesia (GA) in terms of safety, hemodynamic stability, and perioperative complications.<h4>Methods</h4>Patients in the GA group were anesthetized using fentanyl (2 μg kg-1) and propofol (2 mg kg-1). The PFK group was anesthetized using a mixture of which each one ml contains ... Read more >>

Saudi Med J (Saudi medical journal)
[2021, 42(6):629-635]

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Accuracy and Clinical Utility of a Tumor Grade- and Stage-based Predictive Model in Localized Upper Tract Urothelial Carcinoma.

Satoshi Katayama, Keiichiro Mori, Victor M Schuettfort, Benjamin Pradere, Hadi Mostafaei, Fahad Quhal, Pawel Rajwa, Reza Sari Motlagh, Ekaterina Laukhtina, Marco Moschini, Nico C Grossmann, Motoo Araki, Jeremy Yuen-Chun Teoh, Morgan Rouprêt, Vitaly Margulis, Dmitry Enikeev, Pierre I Karakiewicz, Mohammad Abufaraj, Eva Compérat, Yasutomo Nasu, Shahrokh F Shariat,

<h4>Background</h4>Among various clinicopathologic factors used to identify low-risk upper tract urothelial carcinoma (UTUC), tumor grade and stage are of utmost importance. The clinical value added by inclusion of other risk factors remains unproven.<h4>Objective</h4>To assess the performance of a tumor grade- and stage-based (GS) model to identify patients with UTUC for ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Prognostic value of the systemic immune-inflammation index in non-muscle invasive bladder cancer.

Satoshi Katayama, Keiichiro Mori, Benjamin Pradere, Ekaterina Laukhtina, Victor M Schuettfort, Fahad Quhal, Reza Sari Motlagh, Hadi Mostafaei, Nico C Grossmann, Pawel Rajwa, Marco Moschini, Romain Mathieu, Mohammad Abufaraj, David D'Andrea, Eva Compérat, Martin Haydter, Shin Egawa, Yasutomo Nasu, Shahrokh F Shariat, ,

<h4>Purpose</h4>We assessed the prognostic value of systemic immune-inflammation index (SII) to refine risk stratification of the heterogeneous spectrum of patients with non-muscle-invasive bladder cancer (NMIBC) METHODS: In this multi-institutional cohort, preoperative blood-based SII was retrospectively assessed in 1117 patients with NMIBC who underwent transurethral resection of bladder (TURB) between 1996 ... Read more >>

World J Urol (World journal of urology)
[2021, :]

Cited: 1 time

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Pretreatment Risk Stratification for Endoscopic Kidney-sparing Surgery in Upper Tract Urothelial Carcinoma: An International Collaborative Study.

Beat Foerster, Mohammad Abufaraj, Surena F Matin, Mounsif Azizi, Mohit Gupta, Wei-Ming Li, Thomas Seisen, Timothy Clinton, Evanguelos Xylinas, M Carmen Mir, Donald Schweitzer, Andrea Mari, Shoji Kimura, Marco Bandini, Romain Mathieu, Ja H Ku, Gautier Marcq, Georgi Guruli, Markus Grabbert, Anna K Czech, Tim Muilwijk, Armin Pycha, David D'Andrea, Firas G Petros, Philippe E Spiess, Trinity Bivalacqua, Wen-Jeng Wu, Morgan Rouprêt, Laura-Maria Krabbe, Kees Hendricksen, Shin Egawa, Alberto Briganti, Marco Moschini, Vivien Graffeille, Wassim Kassouf, Riccardo Autorino, Axel Heidenreich, Piotr Chlosta, Steven Joniau, Francesco Soria, Phillip M Pierorazio, Shahrokh F Shariat,

<h4>Background</h4>Several groups have proposed features to identify low-risk patients who may benefit from endoscopic kidney-sparing surgery in upper tract urothelial carcinoma (UTUC).<h4>Objective</h4>To evaluate standard risk stratification features, develop an optimal model to identify ≥pT2/N+ stage at radical nephroureterectomy (RNU), and compare it with the existing unvalidated models.<h4>Design, setting, and participants</h4>This ... Read more >>

Eur Urol (European urology)
[2021, 80(4):507-515]

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Diabetic kidney disease in patients with type 2 diabetes mellitus: a cross-sectional study.

Randa I Farah, Mohammed Q Al-Sabbagh, Munther S Momani, Asma Albtoosh, Majd Arabiat, Ahmad M Abdulraheem, Husam Aljabiri, Mohammad Abufaraj,

<h4>Aim</h4>Diabetic kidney disease (DKD) is a major long-term complication of diabetes mellitus (DM). Given the paucity of data on DKD in Jordan, we aimed to evaluate the prevalence, characteristics and correlates of DKD in Jordanian patients with type 2 DM.<h4>Methods</h4>This cross-sectional study included 1398 adult patients with type 2 DM ... Read more >>

BMC Nephrol (BMC nephrology)
[2021, 22(1):223]

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Impact of preoperative plasma levels of interleukin 6 and interleukin 6 soluble receptor on disease outcomes after radical cystectomy for bladder cancer.

Victor M Schuettfort, Benjamin Pradere, Quoc-Dien Trinh, David D'Andrea, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Reza Sari Motlagh, Michael Rink, Pierre I Karakiewicz, Piotr Chlosta, Jeremy Yuen-Chun Teoh, Yair Lotan, Douglas Scherr, Mohammad Abufaraj, Marco Moschini, Shahrokh F Shariat,

<h4>Background</h4>Preoperative plasma levels of Interleukin 6 (IL6) and its soluble receptor (IL6sR) have previously been associated with oncologic outcomes in urothelial carcinoma of the bladder (UCB); however, external validation in patients treated with radical cystectomy (RC) for UCB is missing.<h4>Patients/methods</h4>We prospectively collected preoperative plasma from 1,036 consecutive patients at two ... Read more >>

Cancer Immunol Immunother (Cancer immunology, immunotherapy : CII)
[2021, :]

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Prognostic blood-based biomarkers in patients treated with neoadjuvant chemotherapy for urothelial carcinoma of the bladder: A systematic review.

Ekaterina Laukhtina, Benjamin Pradere, Keiichiro Mori, Victor M Schuettfort, Fahad Quhal, Hadi Mostafaei, Reza Sari Motlagh, Abdulmajeed Aydh, Marco Moschini, Dmitry Enikeev, Pierre I Karakiewicz, Mohammad Abufaraj, Shahrokh F Shariat, ,

<h4>Purpose</h4>The present systematic review aimed to identify prognostic values of blood-based biomarkers in patients treated with neoadjuvant chemotherapy (NAC) for urothelial carcinoma of the bladder (UCB).<h4>Material and methods</h4>The PubMed, Web of Science, and Scopus databases were searched in August 2020 according to the PRISMA statement. Studies were deemed eligible if ... Read more >>

Urol Oncol (Urologic oncology)
[2021, 39(8):471-479]

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Gender-based disparities on health indices during COVID-19 crisis: a nationwide cross-sectional study in Jordan.

Mohammad Abufaraj, Zaid Eyadat, Mohammed Qussay Al-Sabbagh, Abdullah Nimer, Immanuel Azaad Moonesar, Lin Yang, Walid Al Khatib, Ra'eda Al-Qutob,

<h4>Background</h4>COVID-19 has an inevitable burden on public health, potentially widening the gender gap in healthcare and the economy. We aimed to assess gender-based desparities during COVID-19 in Jordan in terms of health indices, mental well-being and economic burden.<h4>Methods</h4>A nationally representative sample of 1300 participants ≥18 years living in Jordan were selected ... Read more >>

Int J Equity Health (International journal for equity in health)
[2021, 20(1):91]

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Surgical intervention in patients with urothelial carcinoma of the bladder and lymph node metastasis.

Mohammad Abufaraj, Abdallah Al-Ani, Alex AlQudah, Shahrokh F Shariat,

<h4>Purpose of review</h4>To systematically review the most recent evidence on the role of surgery in patients with urothelial carcinoma of bladder and lymph node metastasis.<h4>Recent findings</h4>Patients with urothelial carcinoma of bladder and lymph node metastasis have a poor prognosis. The mainstay treatment for these patients is systemic chemotherapy. However, slowly ... Read more >>

Curr Opin Urol (Current opinion in urology)
[2021, 31(3):220-225]

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Novel Classification for Upper Tract Urothelial Carcinoma to Better Risk-stratify Patients Eligible for Kidney-sparing Strategies: An International Collaborative Study.

Gautier Marcq, Beat Foerster, Mohammad Abufaraj, Surena F Matin, Mounsif Azizi, Mohit Gupta, Wei-Ming Li, Thomas Seisen, Timothy Clinton, Evanguelos Xylinas, M Carmen Mir, Donald Schweitzer, Andrea Mari, Shoji Kimura, Marco Bandini, Romain Mathieu, Ja H Ku, Georgi Guruli, Markus Grabbert, Anna K Czech, Tim Muilwijk, Armin Pycha, David D'Andrea, Firas G Petros, Philippe E Spiess, Trinity Bivalacqua, Wen-Jeng Wu, Morgan Rouprêt, Laura-Maria Krabbe, Kees Hendricksen, Shin Egawa, Alberto Briganti, Marco Moschini, Vivien Graffeille, Riccardo Autorino, Patricia John, Axel Heidenreich, Piotr Chlosta, Steven Joniau, Francesco Soria, Phillip M Pierorazio, Shahrokh F Shariat, Wassim Kassouf,

<h4>Background</h4>The European Association of Urology risk stratification dichotomizes patients with upper tract urothelial carcinoma (UTUC) into two risk categories.<h4>Objective</h4>To evaluate the predictive value of a new classification to better risk stratify patients eligible for kidney-sparing surgery (KSS).<h4>Design, setting, and participants</h4>This was a retrospective study including 1214 patients from 21 centers ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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A panel of systemic inflammatory response biomarkers for outcome prediction in patients treated with radical cystectomy for urothelial carcinoma.

Victor M Schuettfort, David D'Andrea, Fahad Quhal, Hadi Mostafaei, Ekaterina Laukhtina, Keiichiro Mori, Frederik König, Michael Rink, Mohammad Abufaraj, Pierre I Karakiewicz, Stefano Luzzago, Morgan Rouprêt, Dmitry Enikeev, Kristin Zimmermann, Marina Deuker, Marco Moschini, Reza Sari Motlagh, Nico C Grossmann, Satoshi Katayama, Benjamin Pradere, Shahrokh F Shariat,

<h4>Objectives</h4>To determine the predictive and prognostic value of a panel of systemic inflammatory response (SIR) biomarkers relative to established clinicopathological variables in order to improve patient selection and facilitate more efficient delivery of peri-operative systemic therapy.<h4>Materials and methods</h4>The preoperative serum levels of a panel of SIR biomarkers, including albumin-globulin ratio, ... Read more >>

BJU Int (BJU international)
[2021, :]

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Intravesical Therapy in Patients with Intermediate-risk Non-muscle-invasive Bladder Cancer: A Systematic Review and Network Meta-analysis of Disease Recurrence.

Ekaterina Laukhtina, Mohammad Abufaraj, Abdallah Al-Ani, Mustafa Rami Ali, Keiichiro Mori, Marco Moschini, Fahad Quhal, Reza Sari Motlagh, Benjamin Pradere, Victor M Schuettfort, Hadi Mostafaei, Satoshi Katayama, Nico C Grossmann, Harun Fajkovic, Francesco Soria, Dmitry Enikeev, Shahrokh F Shariat, ,

<h4>Context</h4>Patients with intermediate-risk non-muscle-invasive bladder cancer (NMIBC) may pose a clinical dilemma without an agreed evidence-based decision tree for personalized treatment.<h4>Objective</h4>To perform a systematic review and network meta-analysis (NMA) to summarize available evidence on the oncologic outcomes of intravesical therapy in patients with intermediate-risk NMIBC.<h4>Evidence acquisition</h4>The MEDLINE, EMBASE, and ClinicalTrials.gov ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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