Full Text Journal Articles by
Author Mohamed A Helal

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Discovery of 3-(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligands.

Nada Elkholy, Ahmad Abdelwaly, Karim Mohamed, Emanuele Amata, Jessica Lombino, Giuseppe Cosentino, Sebastiano Intagliata, Mohamed A Helal,

Sigma receptor is a transmembrane non-GPCR protein expressed mainly in the endoplasmic reticulum membrane associated with mitochondria. It is classified into two types: Sigma-1 (S1R) and Sigma-2 (S2R) based on their biological functions. S1R has been implicated in many neurological disorders such as anxiety, schizophrenia, and depression. Therefore, S1R ligands ... Read more >>

Chem Biol Drug Des (Chemical biology & drug design)
[2022, :]

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Evaluation of the Effect of Different Construction Techniques of CAD-CAM Milled, 3D-Printed, and Polyamide Denture Base Resins on Flexural Strength: An In Vitro Comparative Study.

Ahmed Abd El-Latif Zeidan, Ahmed Fadlallah Sherif, Yasser Baraka, Reem Abualsaud, Ramy Abdallah Abdelrahim, Mohammed M Gad, Mohamed A Helal,

To compare the flexural strength of computer-aided design and computer-aided manufacturing (CAD-CAM) milled denture base resin (DBR), 3D-printed DBR, polyamide, and conventional compression-molded DBR. Six denture base resins were used, one conventional heat-polymerized (Vertex), two milled CAD-CAM (AvaDent and Polident), two 3D-printed (Harz and NextDent), and one flexible polyamide (Polyamide). ... Read more >>

J Prosthodont (Journal of prosthodontics : official journal of the American College of Prosthodontists)
[2022, :]

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