Full Text Journal Articles by
Author Mitchell M Levy

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Temporal Trends in ICU Survival for Coronavirus Disease 2019: A Bumpy Road.

Hallie C Prescott, Mitchell M Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):1986-1988]

Cited: 0 times

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BMI and pneumonia outcomes in critically ill covid-19 patients: An international multicenter study.

Mikael Chetboun, Violeta Raverdy, Julien Labreuche, Arthur Simonnet, Florent Wallet, Cyrielle Caussy, Massimo Antonelli, Antonio Artigas, Gemma Goma, Ferhat Meziani, Julie Helms, Eleftherios Mylonakis, Mitchell M Levy, Markos Kalligeros, Nicola Latronico, Simone Piva, Charles Cerf, Mathilde Neuville, Kada Klouche, Romaric Larcher, Fabienne Tamion, Emilie Occhiali, Morgane Snacken, Jean-Charles Preiser, Loay Kontar, Antoine Riviere, Stein Silva, Benjamine Sarton, Raphael Krouchi, Victoria Dubar, Leonidas Palaiodimos, Dimitrios Karamanis, Juliette Perche, Erwan L'Her, Luca Busetto, Dror Dicker, Shaul Lev, Alain Duhamel, Mercè Jourdain, François Pattou,

<h4>Objective</h4>Previous studies have unveiled a relationship between the severity of coronavirus disease 2019 (COVID-19) pneumonia and obesity. The aims of this multicenter retrospective cohort study were to disentangle the association of BMI and associated metabolic risk factors (diabetes, hypertension, hyperlipidemia, and current smoking status) in critically ill patients with COVID-19.<h4>Methods</h4>Patients ... Read more >>

Obesity (Silver Spring) (Obesity (Silver Spring, Md.))
[2021, 29(9):1477-1486]

Cited: 1 time

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Fluid Therapy and Acute Respiratory Distress Syndrome.

Jisoo Lee, Keith Corl, Mitchell M Levy,

The optimal fluid management for acute respiratory distress syndrome (ARDS) remains unknown. Liberal fluid management may improve cardiac function and end-organ perfusion, but may lead to increased pulmonary edema and inhibit gas exchange. Trials suggest that conservative fluid management leads to better clinical outcomes, although prospective randomized, controlled trials have ... Read more >>

Crit Care Clin (Critical care clinics)
[2021, 37(4):867-875]

Cited: 0 times

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50 Years of Sepsis Investigation/Enlightenment Among Adults-The Long and Winding Road.

R Phillip Dellinger, Mitchell M Levy, Christa A Schorr, Sean R Townsend,

Crit Care Med (Critical care medicine)
[2021, 49(10):1606-1625]

Cited: 0 times

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Effects of Compliance With the Early Management Bundle (SEP-1) on Mortality Changes Among Medicare Beneficiaries With Sepsis: A Propensity Score Matched Cohort Study.

Sean R Townsend, Gary S Phillips, Reena Duseja, Lemeneh Tefera, Derek Cruikshank, Robert Dickerson, H Bryant Nguyen, Christa A Schorr, Mitchell M Levy, R Phillip Dellinger, William A Conway, Warren S Browner, Emanuel P Rivers,

<h4>Background</h4>US hospitals have reported compliance with the SEP-1 quality measure to Medicare since 2015. Finding an association between compliance and outcomes is essential to gauge measure effectiveness.<h4>Research question</h4>What is the association between compliance with SEP-1 and 30-day mortality among Medicare beneficiaries?<h4>Study design and methods</h4>Studying patient-level data reported to Medicare by ... Read more >>

Chest (Chest)
[2021, :]

Cited: 0 times

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The Surviving Sepsis Campaign: research priorities for the administration, epidemiology, scoring and identification of sepsis.

Mark E Nunnally, Ricard Ferrer, Greg S Martin, Ignacio Martin-Loeches, Flavia R Machado, Daniel De Backer, Craig M Coopersmith, Clifford S Deutschman, ,

<h4>Objective</h4>To identify priorities for administrative, epidemiologic and diagnostic research in sepsis.<h4>Design</h4>As a follow-up to a previous consensus statement about sepsis research, members of the Surviving Sepsis Campaign Research Committee, representing the European Society of Intensive Care Medicine and the Society of Critical Care Medicine addressed six questions regarding care delivery, ... Read more >>

Intensive Care Med Exp (Intensive care medicine experimental)
[2021, 9(1):34]

Cited: 1 time

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Using Readmission Rates as a Quality Indicator in Sepsis-Addressing the Problem or Adding to It?

Mitchell M Levy,

JAMA Netw Open (JAMA network open)
[2021, 4(6):e2112873]

Cited: 0 times

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Developing Treatment Guidelines During a Pandemic Health Crisis: Lessons Learned From COVID-19.

Safia Kuriakose, Kanal Singh, Alice K Pau, Eric Daar, Rajesh Gandhi, Pablo Tebas, Laura Evans, Roy M Gulick, H Clifford Lane, Henry Masur, , Judith A Aberg, Adaora A Adimora, Jason Baker, Lisa Baumann Kreuziger, Roger Bedimo, Pamela S Belperio, Stephen V Cantrill, Craig M Coopersmith, Susan L Davis, Amy L Dzierba, John J Gallagher, David V Glidden, Birgit Grund, Erica J Hardy, Carl Hinkson, Brenna L Hughes, Steven Johnson, Marla J Keller, Arthur Y Kim, Jeffrey L Lennox, Mitchell M Levy, Jonathan Z Li, Greg S Martin, Susanna Naggie, Andrew T Pavia, Nitin Seam, Steven Q Simpson, Susan Swindells, Phyllis Tien, Alpana A Waghmare, Kevin C Wilson, Jinoos Yazdany, Philip Zachariah, Danielle M Campbell, Carly Harrison, Timothy Burgess, Joseph Francis, Virginia Sheikh, Timothy M Uyeki, Robert Walker, John T Brooks, Laura Bosque Ortiz, Richard T Davey, Laurie K Doepel, Robert W Eisinger, Alison Han, Elizabeth S Higgs, Martha C Nason, Page Crew, Andrea M Lerner, Claire Lund, Christopher Worthington,

The development of the National Institutes of Health (NIH) COVID-19 Treatment Guidelines began in March 2020 in response to a request from the White House Coronavirus Task Force. Within 4 days of the request, the NIH COVID-19 Treatment Guidelines Panel was established and the first meeting took place (virtually-as did ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2021, 174(8):1151-1158]

Cited: 1 time

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Differences in Family Involvement in the Bedside Care of Patients in the ICU Based on Self-Identified Race.

Eduardo R Nunez, Gianluca Villa, Rory McFadden, Amy Palmisciano, Iacopo Lanini, Sean O'Mahony, J Randall Curtis, Mitchell M Levy, Timothy Amass,

<h4>Objectives</h4>Being a caregiver for a patient in the ICU can place emotional burden on families and engaging families in caregiving can reduce psychological distress. Our goal was to observe support methods used by families in the ICU and identify differences between race/ethnicity.<h4>Design</h4>A secondary analysis of a multicenter before-and-after clinical trial.<h4>Setting</h4>Three ... Read more >>

Crit Care Explor (Critical care explorations)
[2021, 3(3):e0365]

Cited: 0 times

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Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update.

Waleed Alhazzani, Laura Evans, Fayez Alshamsi, Morten Hylander Møller, Marlies Ostermann, Hallie C Prescott, Yaseen M Arabi, Mark Loeb, Michelle Ng Gong, Eddy Fan, Simon Oczkowski, Mitchell M Levy, Lennie Derde, Amy Dzierba, Bin Du, Flavia Machado, Hannah Wunsch, Mark Crowther, Maurizio Cecconi, Younsuck Koh, Lisa Burry, Daniel S Chertow, Wojciech Szczeklik, Emilie Belley-Cote, Massimiliano Greco, Malgorzata Bala, Ryan Zarychanski, Jozef Kesecioglu, Allison McGeer, Leonard Mermel, Manoj J Mammen, Sheila Nainan Myatra, Amy Arrington, Ruth Kleinpell, Giuseppe Citerio, Kimberley Lewis, Elizabeth Bridges, Ziad A Memish, Naomi Hammond, Frederick G Hayden, Muhammed Alshahrani, Zainab Al Duhailib, Greg S Martin, Lewis J Kaplan, Craig M Coopersmith, Massimo Antonelli, Andrew Rhodes,

<h4>Background</h4>The coronavirus disease 2019 pandemic continues to affect millions worldwide. Given the rapidly growing evidence base, we implemented a living guideline model to provide guidance on the management of patients with severe or critical coronavirus disease 2019 in the ICU.<h4>Methods</h4>The Surviving Sepsis Campaign Coronavirus Disease 2019 panel has expanded to ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(3):e219-e234]

Cited: 37 times

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Survival From Severe Coronavirus Disease 2019: Is It Changing?

Hallie C Prescott, Mitchell M Levy,

Crit Care Med (Critical care medicine)
[2021, 49(2):351-353]

Cited: 2 times

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The authors reply.

Keith A Corl, Mitchell M Levy, Aisling R Caffrey, Kerry L LaPlante,

Crit Care Med (Critical care medicine)
[2020, 48(12):e1371-e1372]

Cited: 0 times

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Correlation Between Restraint Use and Engaging Family Members in the Care of ICU Patients.

Sarah J Hochendoner, Gianluca Villa, Emily Sokol, Mitchell M Levy, Jason M Aliotta, Sarah J Timothy H Amass,

Crit Care Explor (Critical care explorations)
[2020, 2(11):e0255]

Cited: 0 times

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Increasing Quality, Not Costs.

Mitchell M Levy,

Crit Care Med (Critical care medicine)
[2020, 48(10):1528-1529]

Cited: 0 times

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Convalescent Plasma for the Treatment of COVID-19: Perspectives of the National Institutes of Health COVID-19 Treatment Guidelines Panel.

Alice K Pau, Judith Aberg, Jason Baker, Pamela S Belperio, Craig Coopersmith, Page Crew, Birgit Grund, Roy M Gulick, Carly Harrison, Arthur Kim, H Clifford Lane, Henry Masur, Virginia Sheikh, Kanal Singh, Jinoos Yazdany, Pablo Tebas, ,

Ann Intern Med (Annals of internal medicine)
[2021, 174(1):93-95]

Cited: 14 times

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Change in Carotid Blood Flow and Carotid Corrected Flow Time Assessed by Novice Sonologists Fails to Determine Fluid Responsiveness in Spontaneously Breathing Intensive Care Unit Patients.

Adeel Abbasi, Nader Azab, Mohammed Nayeemuddin, Alexandra Schick, Thomas Lopardo, Gary S Phillips, Roland C Merchant, Mitchell M Levy, Michael Blaivas, Keith A Corl,

Measurement of carotid blood flow (CBF) and corrected carotid flow time (ccFT) has been proposed as a non-invasive means of determining fluid responsiveness. We evaluated the ability of CBF and ccFT as assessed by novice sonologists to determine fluid responsiveness in intensive care unit patients. Three novice physician sonologists performed ... Read more >>

Ultrasound Med Biol (Ultrasound in medicine & biology)
[2020, 46(10):2659-2666]

Cited: 0 times

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The authors reply.

Timothy Amass, Mitchell M Levy,

Crit Care Med (Critical care medicine)
[2020, 48(9):e841-e842]

Cited: 0 times

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Respiratory Variation in Carotid Artery Peak Systolic Velocity Is Unable to Predict Fluid Responsiveness in Spontaneously Breathing Critically Ill Patients When Assessed by Novice Physician Sonologists.

Adeel Abbasi, Mohammed Nayeemuddin, Nader Azab, Alexandra Schick, Thomas Lopardo, Gary S Phillips, Roland C Merchant, Mitchell M Levy, Michael Blaivas, Keith A Corl,

<h4>Background</h4>Respiratory variation in carotid artery peak systolic velocity (ΔVpeak) assessed by point-of-care ultrasound (POCUS) has been proposed as a noninvasive means to predict fluid responsiveness. We aimed to evaluate the ability of carotid ΔVpeak as assessed by novice physician sonologists to predict fluid responsiveness.<h4>Methods</h4>This study was conducted in 2 intensive ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2021, 36(8):885-892]

Cited: 0 times

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The surviving sepsis campaign: basic/translational science research priorities.

Clifford S Deutschman, Judith Hellman, Ricard Ferrer Roca, Daniel De Backer, Craig M Coopersmith, ,

<h4>Objectives</h4>Expound upon priorities for basic/translational science identified in a recent paper by a group of experts assigned by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine.<h4>Data sources</h4>Original paper, search of the literature.<h4>Study selection</h4>This study is selected by several members of the original task force ... Read more >>

Intensive Care Med Exp (Intensive care medicine experimental)
[2020, 8(1):31]

Cited: 2 times

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Recombinant Human Proteoglycan-4 Mediates Interleukin-6 Response in Both Human and Mouse Endothelial Cells Induced Into a Sepsis Phenotype.

Holly A Richendrfer, Mitchell M Levy, Khaled A Elsaid, Tannin A Schmidt, Ling Zhang, Ralph Cabezas, Gregory D Jay,

<h4>Objectives</h4>Sepsis is a leading cause of death in the United States. Putative targets to prevent systemic inflammatory response syndrome include antagonism of toll-like receptors 2 and 4 and CD44 receptors in vascular endothelial cells. Proteoglycan-4 is a mucinous glycoprotein that interacts with CD44 and toll-like receptor 4 resulting in a ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(6):e0126]

Cited: 1 time

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Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial.

Ivor S Douglas, Philip M Alapat, Keith A Corl, Matthew C Exline, Lui G Forni, Andre L Holder, David A Kaufman, Akram Khan, Mitchell M Levy, Gregory S Martin, Jennifer A Sahatjian, Eric Seeley, Wesley H Self, Jeremy A Weingarten, Mark Williams, Douglas M Hansell,

<h4>Background</h4>Fluid and vasopressor management in septic shock remains controversial. In this randomized controlled trial, we evaluated the efficacy of dynamic measures (stroke volume change during passive leg raise) to guide resuscitation and improve patient outcome.<h4>Research question</h4>Will resuscitation that is guided by dynamic assessments of fluid responsiveness in patients with septic ... Read more >>

Chest (Chest)
[2020, 158(4):1431-1445]

Cited: 12 times

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Identifying the Burden of Sepsis With Big Data.

Mitchell M Levy,

Crit Care Med (Critical care medicine)
[2020, 48(3):422-423]

Cited: 0 times

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Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus aureus Bacteremia.

Keith A Corl, Fatima Zeba, Aisling R Caffrey, Matthew Hermenau, Vrishali Lopes, Gary Phillips, Roland C Merchant, Mitchell M Levy, Kerry L LaPlante,

<h4>Objectives</h4>The relationship between the timing of antibiotics and mortality among septic shock patients has not been examined among patients specifically with Staphylococcus aureus bacteremia.<h4>Design</h4>Retrospective analysis of a Veterans Affairs S. aureus bacteremia database.<h4>Setting</h4>One-hundred twenty-two hospitals in the Veterans Affairs Health System.<h4>Patients</h4>Patients with septic shock and S. aureus bacteremia admitted directly ... Read more >>

Crit Care Med (Critical care medicine)
[2020, 48(4):525-532]

Cited: 4 times

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Effect of Best Practice Advisories on Sedation Protocol Compliance and Drug-Related Hazardous Condition Mitigation Among Critical Care Patients.

Rebecca A Greene, Andrew R Zullo, Craig M Mailloux, Christine Berard-Collins, Mitchell M Levy, Timothy Amass,

OBJECTIVES:To determine whether best practice advisories improved sedation protocol compliance and could mitigate potential propofol-related hazardous conditions. DESIGN:Retrospective observational cohort study. SETTING:Two adult ICUs at two academic medical centers that share the same sedation protocol. PATIENTS:Adults 18 years old or older admitted to the ICU between January 1, 2016, and ... Read more >>

Crit Care Med (Critical care medicine)
[2020, 48(2):185-191]

Cited: 0 times

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Effect of Dexmedetomidine on duration of mechanical ventilation in septic patients: a systematic review and meta-analysis.

Peifen Chen, Jihong Jiang, Yunhe Zhang, Guobao Li, Zhihui Qiu, Mitchell M Levy, Baoji Hu,

BACKGROUND:Because of its analgesic and light sedative properties, the highly selective alpha-2 adrenergic receptor agonist dexmedetomidine (DEX) has been suggested for the treatment of septic patients, but its effect on the duration of mechanical ventilation remains unclear. The present study was conducted to review the extant literature in DEX and ... Read more >>

BMC Pulm Med (BMC pulmonary medicine)
[2020, 20(1):42]

Cited: 2 times

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