Full Text Journal Articles by
Author Mitchell Ferguson

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High accuracy gene expression profiling of sorted cell subpopulations from breast cancer PDX model tissue.

Warren Porter, Eileen Snowden, Friedrich Hahn, Mitchell Ferguson, Frances Tong, W Shannon Dillmore, Rainer Blaesius,

Intratumor Heterogeneity (ITH) is a functionally important property of tumor tissue and may be involved in drug resistance mechanisms. Although descriptions of ITH can be traced back to very early reports about cancer tissue, mechanistic investigations are still limited by the precision of analysis methods and access to relevant tissue ... Read more >>

PLoS One (PloS one)
[2020, 15(9):e0238594]

Cited: 0 times

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Correction: Flow based single cell analysis of the immune landscape distinguishes Barrett's esophagus from adjacent normal tissue.

Moen Sen, Friedrich Hahn, Taylor A Black, Maureen DeMarshall, Warren Porter, Eileen Snowden, Stephanie S Yee, Frances Tong, Mitchell Ferguson, Emylee N Fleshman, Hiroshi Nakagawa, Gary W Falk, Gregory G Ginsberg, Michael L Kochman, Rainer Blaesius, Anil K Rustgi, Erica L Carpenter,

[This corrects the article DOI: 10.18632/oncotarget.26911.]. ... Read more >>

Oncotarget (Oncotarget)
[2019, 10(49):5119]

Cited: 0 times

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Flow based single cell analysis of the immune landscape distinguishes Barrett's esophagus from adjacent normal tissue.

Moen Sen, Friedrich Hahn, Taylor A Black, Maureen DeMarshall, Warren Porter, Eileen Snowden, Stephanie S Yee, Frances Tong, Mitchell Ferguson, Emylee N Fleshman, Hiroshi Nakagawa, Gary W Falk, Gregory G Ginsberg, Michael L Kochman, Rainer Blaesius, Anil K Rustgi, Erica L Carpenter,

Barrett's esophagus (BE) is metaplasia of the squamous epithelium to a specialized columnar epithelium. BE progresses through low- and high-grade dysplasia before developing into esophageal adenocarcinoma. The BE microenvironment is not well defined. We compare 12 human clinical BE and adjacent normal squamous epithelium biopsies using single cell immunophenotyping by ... Read more >>

Oncotarget (Oncotarget)
[2019, 10(38):3592-3604]

Cited: 3 times

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Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue.

Eileen Snowden, Warren Porter, Friedrich Hahn, Mitchell Ferguson, Frances Tong, Joel S Parker, Aaron Middlebrook, Smita Ghanekar, W Shannon Dillmore, Rainer Blaesius,

Cancer tissue functions as an ecosystem of a diverse set of cells that interact in a complex tumor microenvironment. Genomic tools applied to biopsies in bulk fail to account for this tumor heterogeneity, whereas single-cell imaging methods limit the number of cells which can be assessed or are very resource ... Read more >>

Mol Cancer Res (Molecular cancer research : MCR)
[2017, 15(4):429-438]

Cited: 4 times

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MK-7128, a novel CB1 receptor inverse agonist, improves scopolamine-induced learning and memory deficits in mice.

Gregory M Dillon, Laura S Lubbers, Mitchell T Ferguson, Julie Z Lao, Ruey-Ruey C Huang, Jing C Xiao, Tung M Fong, Jeffrey J Hale, Kathleen Rupprecht, Shouwu Miao, Blake A Rowe, Thomas J Kornecook, Jean-Cosme Dodart,

Cannabinoid receptors (CBRs) play an important role in a variety of physiological functions and have been considered drug targets for obesity and psychiatric disorders. In particular, the CB1R is highly expressed in brain regions crucial to learning and memory processes, and several lines of evidence indicate that pharmacological blockade of ... Read more >>

Behav Pharmacol (Behavioural pharmacology)
[2011, 22(2):91-100]

Cited: 5 times

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Prefrontal cortex lesions and scopolamine impair attention performance of C57BL/6 mice in a novel 2-choice visual discrimination task.

Gregory M Dillon, Delia Shelton, A P McKinney, Michael Caniga, Jacob N Marcus, Mitchell T Ferguson, Thomas J Kornecook, Jean-Cosme Dodart,

Sustained attention is defined as the ability or capacity to remain focused on the occurrence of rare events over long periods of time. We describe here the development of a novel, operant-based attention task that can be learned by mice in 8-10 days. Mice were trained on a 2-choice visual ... Read more >>

Behav. Brain Res. (Behavioural brain research)
[2009, 204(1):67-76]

Cited: 14 times

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Persistent increases in the pool of doublecortin-expressing neurons in the hippocampus following spatial navigation training.

Julian R Keith, Carolina Priester, Mitchell Ferguson, Michael Salling, Aneeka Hancock,

In addition to its role in neuronal migration during embryonic development, doublecortin (DCX) plays a role in hippocampal neurogenesis across the lifespan. Hippocampal neurons exhibit a high degree of synaptic plasticity while they are in the DCX phase. While previous studies have reported that behavioral training on hippocampus-dependent tasks can ... Read more >>

Behav Brain Res (Behavioural brain research)
[2008, 188(2):391-397]

Cited: 7 times

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