Full Text Journal Articles by
Author Miriam Rottmann

Advertisement

Find full text journal articles








Primary platinum resistance and its prognostic impact in patients with recurrent ovarian cancer: an analysis of three prospective trials from the NOGGO study group.

Fabian Trillsch, Sven Mahner, Bastian Czogalla, Miriam Rottmann, Radoslav Chekerov, Elena Ioana Braicu, Gülten Oskay-Öczelik, Pauline Wimberger, Rolf Richter, Jalid Sehouli,

<h4>Objective</h4>Patients with platinum-resistant ovarian cancer (PROC) have a high need for reliable prognostic markers. Since significance of primary platinum resistance (PPR) versus secondary platinum resistance (SPR) was identified for patients receiving anti-angiogenic therapy, it has not been confirmed for chemotherapy only.<h4>Methods</h4>PROC patients from 3 prospective trials of the NOGGO study ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(3):e37]

Cited: 0 times

View full text PDF listing >>



The G-Protein-Coupled Estrogen Receptor (GPER) Regulates Trimethylation of Histone H3 at Lysine 4 and Represses Migration and Proliferation of Ovarian Cancer Cells In Vitro.

Nan Han, Sabine Heublein, Udo Jeschke, Christina Kuhn, Anna Hester, Bastian Czogalla, Sven Mahner, Miriam Rottmann, Doris Mayr, Elisa Schmoeckel, Fabian Trillsch,

Histone H3 lysine 4 trimethylation (H3K4me3) is one of the most recognized epigenetic regulators of transcriptional activity representing, an epigenetic modification of Histone H3. Previous reports have suggested that the broad H3K4me3 domain can be considered as an epigenetic signature for tumor-suppressor genes in human cells. G-protein-coupled estrogen receptor (GPER), ... Read more >>

Cells (Cells)
[2021, 10(3):]

Cited: 0 times

View full text PDF listing >>



Advertisement

Empirical analysis of the text structure of original research articles in medical journals.

Nicole Heßler, Miriam Rottmann, Andreas Ziegler,

Successful publishing of an article depends on several factors, including the structure of the main text, the so-called introduction, methods, results and discussion structure (IMRAD). The first objective of our work is to provide recent results on the number of paragraphs (pars.) per section used in articles published in major ... Read more >>

PLoS One (PloS one)
[2020, 15(10):e0240288]

Cited: 1 time

View full text PDF listing >>



H3K4me3 Is a Potential Mediator for Antiproliferative Effects of Calcitriol (1α,25(OH)2D3) in Ovarian Cancer Biology.

Nan Han, Udo Jeschke, Christina Kuhn, Anna Hester, Bastian Czogalla, Sven Mahner, Miriam Rottmann, Doris Mayr, Elisa Schmoeckel, Fabian Trillsch,

Posttranslational histone modification plays an important role in tumorigenesis. Histone modification is a dynamic response of chromatin to various signals, such as the exposure to calcitriol (1α,25(OH)<sub>2</sub>D<sub>3</sub>). Recent studies suggested that histone modification levels could be used to predict patient outcomes in various cancers. Our study evaluated the expression level ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(6):]

Cited: 1 time

View full text PDF listing >>



PD-L1 expression and survival in p16-negative and -positive squamous cell carcinomas of the vulva.

Bastian Czogalla, Deborah Pham, Fabian Trillsch, Miriam Rottmann, Julia Gallwas, Alexander Burges, Sven Mahner, Thomas Kirchner, Udo Jeschke, Doris Mayr, Elisa Schmoeckel,

AIM:Programmed death-ligand 1 (PD-L1) has become a widely used predictive biomarker for therapy with checkpoint inhibitors in a variety of cancers. Here, we studied the expression of PD-L1 in squamous cell carcinomas of the vulva (SCCV) with regard to HPV status via its surrogate marker p16. Additionally, the status of PD-L1 ... Read more >>

J Cancer Res Clin Oncol (Journal of cancer research and clinical oncology)
[2020, 146(3):569-577]

Cited: 4 times

View full text PDF listing >>



Comprehensive analysis of PD-L1 expression, HER2 amplification, ALK/EML4 fusion, and mismatch repair deficiency as putative predictive and prognostic factors in ovarian carcinoma.

Elisa Schmoeckel, Sophie Hofmann, Daniel Fromberger, Miriam Rottmann, Beate Luthardt, Alexander Burges, Udo Jeschke, Thomas Kirchner, Sigurd F Lax, Doris Mayr,

Most ovarian carcinomas (OC) are characterized by poor prognosis, particularly the most frequent type high-grade serous carcinoma. Besides PARP inhibitors, target-based therapeutic strategies are not well established. We asked the question which other therapeutic targets could be of potential value and, therefore, analyzed a large cohort of OC for several ... Read more >>

Virchows Arch (Virchows Archiv : an international journal of pathology)
[2019, 474(5):599-608]

Cited: 2 times

View full text PDF listing >>



COMPLIANCE AND ADHERENCE OF PATIENTS WITH DIABETIC MACULAR EDEMA TO INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY IN DAILY PRACTICE.

Maximilian Weiss, Dawn A Sim, Tina Herold, Ricarda G Schumann, Raffael Liegl, Christoph Kern, Thomas Kreutzer, Johannes Schiefelbein, Miriam Rottmann, Siegfried Priglinger, Karsten Ulrich KortUEm,

<h4>Purpose</h4>We assessed differences in compliance and adherence (lateness of patients, visual acuity, reasons for abstaining) between patients with diabetic macular edema (DME) and patients with age-related macular degeneration (AMD), both under anti-vascular endothelial growth factor therapy.<h4>Methods</h4>We included 136 patients with DME (36% women, 65 years, 22 visits, 13.9 injections, and ... Read more >>

Retina (Retina (Philadelphia, Pa.))
[2018, 38(12):2293-2300]

Cited: 13 times

View full text PDF listing >>



The ARID1A, p53 and ß-Catenin statuses are strong prognosticators in clear cell and endometrioid carcinoma of the ovary and the endometrium.

Marlene Heckl, Elisa Schmoeckel, Linda Hertlein, Miriam Rottmann, Udo Jeschke, Doris Mayr,

AIM:The objective of this study was to evaluate the prognostic value of ARID1A, p53, p21, p16 and ß-Catenin in endometrioid and clear cell ovarian and endometrial carcinomas. MATERIALS AND METHODS:97 tumors were available for analysis of ARID1A, p53, p21, p16 and ß-Catenin with the techniques of tissue microarray and immunohistochemistry. ... Read more >>

PLoS One (PloS one)
[2018, 13(2):e0192881]

Cited: 8 times

View full text PDF listing >>



LEF1 is preferentially expressed in the tubal-peritoneal junctions and is a reliable marker of tubal intraepithelial lesions.

Elisa Schmoeckel, Ashley A Odai-Afotey, Michael Schleißheimer, Miriam Rottmann, Andrea Flesken-Nikitin, Lora H Ellenson, Thomas Kirchner, Doris Mayr, Alexander Yu Nikitin,

Recently it has been reported that serous tubal intraepithelial carcinoma (STIC), the likely precursor of ovarian/extra-uterine high-grade serous carcinoma, are frequently located in the vicinity of tubal-peritoneal junctions, consistent with the cancer-prone features of many epithelial transitional regions. To test if p53 (aka TP53)-signatures and secretory cell outgrowths (SCOUTs) also ... Read more >>

Mod Pathol (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2017, 30(9):1241-1250]

Cited: 7 times

View full text PDF listing >>



Cancer of the ovary, fallopian tube, and peritoneum: a population-based comparison of the prognostic factors and outcomes.

Miriam Rottmann, A Burges, S Mahner, C Anthuber, T Beck, D Grab, A Schnelzer, M Kiechle, D Mayr, M Pölcher, G Schubert-Fritschle, J Engel,

<h4>Purpose</h4>The objective was to compare the prognostic factors and outcomes among primary ovarian cancer (OC), fallopian tube cancer (FC), and peritoneal cancer (PC) patients in a population-based setting.<h4>Methods</h4>We analysed 5399 OC, 327 FC, and 416 PC patients diagnosed between 1998 and 2014 in the catchment area of the Munich Cancer ... Read more >>

J Cancer Res Clin Oncol (Journal of cancer research and clinical oncology)
[2017, 143(9):1833-1844]

Cited: 5 times

View full text PDF listing >>



Projections of cancer incidence and cancer-related deaths in Germany by 2020 and 2030.

Anne S Quante, Chang Ming, Miriam Rottmann, Jutta Engel, Stefan Boeck, Volker Heinemann, Christoph Benedikt Westphalen, Konstantin Strauch,

Past patterns of cancer disease and future changes in the demographic structure have a major influence on the projected incidences of human malignancies. In Germany, nearly a quarter of men and 20% of women die of cancer, and it is estimated that in Germany around 51% men and 43% women will ... Read more >>

Cancer Med (Cancer medicine)
[2016, 5(9):2649-2656]

Cited: 40 times

View full text PDF listing >>



Outcome of gastric cancer in the elderly: a population-based evaluation of the Munich Cancer Registry.

Anne Schlesinger-Raab, André L Mihaljevic, Silvia Egert, Rebecca Emeny, Karl-Walter Jauch, Jörg Kleeff, Alexander Novotny, Natascha C Nüssler, Miriam Rottmann, Wolfgang Schepp, Wolfgang Schmitt, Gabriele Schubert-Fritschle, Bernhard Weber, Christoph Schuhmacher, Jutta Engel,

<h4>Background</h4>Gastric cancer accounts for 5 % of cancer deaths. Proportions of older stomach cancer patients are increasing. Despite the still poor prognosis, standardised treatment has achieved improvements; nonetheless it is questionable whether all age groups have benefitted. Age and outcome need to be examined in a population-based setting.<h4>Methods</h4>Analyses included Munich Cancer ... Read more >>

Gastric Cancer (Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association)
[2016, 19(3):713-722]

Cited: 14 times

View full text PDF listing >>



Level of hospital care and outcome of gastric cancer: a population-based evaluation of the Munich Cancer Registry.

Anne Schlesinger-Raab, André L Mihaljevic, Silvia Egert, Rebecca T Emeny, Karl-Walter Jauch, Jörg Kleeff, Alexander Novotny, Natascha C Nüssler, Miriam Rottmann, Wolfgang Schepp, Wolfgang Schmitt, Gabriele Schubert-Fritschle, Bernhard Weber, Christoph Schuhmacher, Jutta Engel,

<h4>Background</h4>Gastric cancer accounts for 5 % of cancer deaths. Successful implementation of guideline-recommended treatment procedures should result in population-based outcome improvements despite the still poor prognosis. In this context, the objective of this study was to compare the outcome of gastric cancer by different levels of hospital care.<h4>Materials and methods</h4>Total ... Read more >>

J Cancer Res Clin Oncol (Journal of cancer research and clinical oncology)
[2014, 140(5):789-800]

Cited: 3 times

View full text PDF listing >>





Advertisement

Disclaimer
0.9881 s