Full Text Journal Articles by
Author Ming Wun Wong

Advertisement

Find full text journal articles






Editorial: time to retire Rome IV and the Montreal definition? Authors' reply.

Ming-Wun Wong, Chien-Lin Chen,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(8):1083-1084]

Cited: 0 times

View full text PDF listing >>



Effects of menthol on esophageal motility in humans: Studies using high-resolution manometry.

Wei-Yi Lei, Shu-Wei Liang, Jui-Sheng Hung, Ming-Wun Wong, Tso-Tsai Liu, Chih-Hsun Yi, Lin Lin, William C Orr, Chien-Lin Chen,

<h4>Background/aim</h4>The cold receptor, transient receptor potential melastatin 8 (TRPM8), has been reported to be expressed in esophageal vagal afferents. Esophageal infusion of menthol modulates esophageal perception in reflux patients via TRPM8, but the effects of menthol on esophageal motility are not well investigated. This study aimed to test the hypothesis ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2021, :e14267]

Cited: 0 times

View full text PDF listing >>



Advertisement

Oesophageal hypervigilance and visceral anxiety relate to reflux symptom severity and psychological distress but not to acid reflux parameters.

Ming-Wun Wong, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Charles Cock, Taher Omari, Chandra Prakash Gyawali, Shu-Wei Liang, Lin Lin, Chien-Lin Chen,

<h4>Background</h4>The pathogenesis of gastro-oesophageal reflux disease (GERD) is complex and multifactorial. The oesophageal hypervigilance and anxiety scale (EHAS) is a novel cognitive-affective evaluation of visceral sensitivity.<h4>Aims</h4>To investigate the interrelationship between EHAS and reflux symptom severity, psychological stress, acid reflux burden, phenotypes, and oesophageal mucosal integrity in patients with GERD.<h4>Methods</h4>Patients with ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(7):923-930]

Cited: 0 times

View full text PDF listing >>



Effects of codeine on esophageal peristalsis in humans using high resolution manometry.

Chien-Lin Chen, Ming-Wun Wong, Jui-Sheng Hung, Shu-Wei Liang, Tso-Tsai Liu, Chih-Hsun Yi, Lin Lin, William C Orr, Wei-Yi Lei,

<h4>Background and aim</h4>Opioid receptors agonists have been demonstrated to impair lower esophageal sphincter (LES) relaxation and induce spastic esophageal dysmotility, but little was known for their impact on distension-induced secondary peristalsis. The aim of the study was to investigate the hypothesis whether acute administration of codeine can influence physiological characteristics ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Esophageal acid burden in reflux patients with normal endoscopy: Does esophageal peristalsis matter?

Ming-Wun Wong, Jui-Sheng Hung, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Shu-Wei Liang, William C Orr, Chien-Lin Chen,

<h4>Background</h4>A majority of patients with gastroesophageal reflux disease (GERD) have normal endoscopy. We aimed to investigate whether esophageal primary and secondary peristalsis influence esophageal reflux parameters in patients with normal endoscopy.<h4>Methods</h4>We enrolled consecutive patients with typical reflux symptoms and normal endoscopy. All patients underwent High resolution manometry (HRM) and 24-h ... Read more >>

J Formos Med Assoc (Journal of the Formosan Medical Association = Taiwan yi zhi)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Analysis of contractile segment impedance during straight leg raise maneuver using high-resolution impedance manometry increases diagnostic yield in reflux disease.

Ming-Wun Wong, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Taher Omari, Charles Cock, Shu-Wei Liang, Chandra Prakash Gyawali, Chien-Lin Chen,

<h4>Background</h4>Contractile segment impedance (CSI) obtained from high-resolution impedance manometry (HRIM) is a measure of mucosal integrity that predicts gastroesophageal reflux disease (GERD). While straight leg raise (SLR) maneuver augments esophageal peristaltic vigor, it remains unclear whether SLR affects CSI values. This study was aimed to evaluate whether CSI with SLR ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2021, :e14135]

Cited: 0 times

View full text PDF listing >>



An Uncommon Ectopic Duodenal Varices Hemorrhage in Cirrhotic Patient Managed With the Enteroscope.

Hsiang-Yu Hsu, Ming-Wun Wong, Chien-Lin Chen,

Am J Med Sci (The American journal of the medical sciences)
[2021, 362(3):e25]

Cited: 0 times

View full text PDF listing >>



Impact of ineffective esophageal motility on secondary peristalsis: Studies with high-resolution manometry.

Wei-Yi Lei, Tso-Tsai Liu, Jen-Hung Wang, Chih-Hsun Yi, Jui-Sheng Hung, Ming-Wun Wong, Chandra Prakash Gyawali, Chien-Lin Chen,

<h4>Background/aim</h4>The aim was to investigate whether there is a difference in secondary peristalsis on high-resolution manometry (HRM) among gastroesophageal reflux disease (GERD) patients with and without ineffective esophageal motility (IEM), and healthy individuals.<h4>Methods</h4>Twenty-eight GERD patients and seventeen healthy controls were included. Secondary peristalsis was stimulated by a rapid injection of ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2021, 33(4):e14024]

Cited: 0 times

View full text PDF listing >>



Effect of prucalopride on sildenafil-induced inhibition of esophageal peristalsis in healthy adults.

Ming-Wun Wong, Tso-Tsai Liu, Chih-Hsun Yi, Jui-Sheng Hung, Wei-Yi Lei, Shu-Wei Liang, William C Orr, Chien-Lin Chen,

<h4>Background and aim</h4>Prucalopride, a high-affinity 5-hydroxytryptamine 4 receptor agonist, promotes esophageal peristalsis, while phosphodiesterase type 5 inhibitor sildenafil inhibits esophageal peristalsis. The present study was aimed to evaluate whether prucalopride would augment esophageal peristalsis subsequent to the application of sildenafil.<h4>Methods</h4>Seventeen healthy adults underwent high-resolution manometry by a catheter with one ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2021, 36(6):1556-1561]

Cited: 0 times

View full text PDF listing >>



Application of a novel straight leg raise test during high-resolution manometry can predict esophageal contractile reserve in patients with gastroesophageal reflux disease.

Wei-Yi Lei, C Prakash Gyawali, Wei-Chuan Chang, Sabine Roman, Ming Wun Wong, Chih-Hsun Yi, Tso-Tsai Liu, Jui-Sheng Hung, Shu-Wei Liang, Chien-Lin Chen,

<h4>Background/aim</h4>Increased intra-abdominal pressure from abdominal compression augments esophageal peristalsis during high-resolution manometry (HRM), and straight leg raise (SLR) while supine increases intra-abdominal pressure. We determined if water swallows performed during SLR can mimic contraction reserve seen with multiple rapid swallows (MRS).<h4>Methods</h4>Consecutive patients evaluated for GERD symptoms completed validated GERD questionnaires, ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2021, 33(3):e13996]

Cited: 0 times

View full text PDF listing >>



Effects of phosphodiesterase-5 inhibitor sildenafil on esophageal secondary peristalsis: Studies with high-resolution manometry.

Ming-Wun Wong, Chih-Hsun Yi, Tso-Tsai Liu, Wei-Yi Lei, Jui-Sheng Hung, Chao-Zong Liu, Chien-Lin Chen,

<h4>Background and aim</h4>Secondary peristalsis contributes to the clearance of retained refluxate from the esophagus. Sildenafil, a phosphodiesterase-5 inhibitor, inhibits primary esophageal peristalsis, but its effects on secondary peristalsis remain unknown. This study sought to investigate whether sildenafil could influence physiological characteristics of secondary peristalsis by applying high-resolution manometry (HRM).<h4>Methods</h4>Seventeen healthy ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2021, 36(2):430-435]

Cited: 0 times

View full text PDF listing >>



Influence of sildenafil on esophageal motor function in humans: Studies using high-resolution manometry.

Ming-Wun Wong, Jui-Sheng Hung, Wei-Yi Lei, Chih-Hsun Yi, Tso-Tsai Liu, Chien-Lin Chen,

<h4>Background/aim</h4>Sildenafil induces smooth muscle relaxation of the esophagus by blocking type 5 phosphodiesterase that degrades cyclic guanine monophosphate. We aimed to characterize the effects of sildenafil on esophageal peristalsis and contraction reserve using high-resolution manometry (HRM).<h4>Methods</h4>Fifteen healthy adults (12 men, age 21-39, mean 27 years) participated in this study using HRM ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2020, 32(7):e13840]

Cited: 0 times

View full text PDF listing >>



Association between use of proton pump inhibitors and colorectal cancer: A nationwide population-based study.

Wei-Yi Lei, Jen-Hung Wang, Chih-Hsun Yi, Tso-Tsai Liu, Jui-Sheng Hung, Ming-Wun Wong, Ming-Jong Bair, Michael F Vaezi, William C Orr, Chien-Lin Chen,

<h4>Background</h4>Proton pump inhibitors (PPIs) use is associated with hypergastrinemia and gut microbiota alteration. Concern over the risk that these factors may increase chances of colorectal cancer (CRC) has risen. To investigate the association between PPIs use and CRC using a large population-based cohort and examine whether the PPIs may differ ... Read more >>

Clin Res Hepatol Gastroenterol (Clinics and research in hepatology and gastroenterology)
[2021, 45(1):101397]

Cited: 3 times

View full text PDF listing >>



Effects of GABA-B agonist baclofen on esophageal motility: Studies using high-resolution manometry.

Jui-Sheng Hung, Chih-Hsun Yi, Tso-Tsai Liu, Wei-Yi Lei, Ming-Wun Wong, Chien-Lin Chen,

<h4>Background/aim</h4>Baclofen inhibits transient lower esophageal sphincter (LES) relaxation. This study aimed to investigate the effect of baclofen on esophageal peristaltic function and contraction reserve in healthy adults using high-resolution manometry (HRM).<h4>Methods</h4>Fifteen subjects underwent HRM with ten water swallows and five multiple rapid swallows (MRS) 90 minutes after oral intake of either ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2019, 31(12):e13716]

Cited: 0 times

View full text PDF listing >>



An Uncommon Cause of Gastric Varix and Ascites.

Shu-Wei Liang, Ming-Wun Wong, Chien-Lin Chen,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2020, 18(10):e118]

Cited: 0 times

View full text PDF listing >>



Predicting factors of recurrence in patients with gastroesophageal reflux disease: a prospective follow-up analysis.

Wei-Yi Lei, Wei-Chuan Chang, Shu-Hui Wen, Chih-Hsun Yi, Tso-Tsai Liu, Jui-Sheng Hung, Ming-Wun Wong, Chien-Lin Chen,

<h4>Background</h4>Recurrence of gastroesophageal reflux disease (GERD) is common among patients who are no longer receiving proton pump inhibitors (PPIs). This study investigated factors associated with GERD recurrence.<h4>Methods</h4>We included 499 consecutive GERD patients who completed validated reflux and psychological questionnaires before undergoing upper endoscopy. All patients were treated with PPIs and ... Read more >>

Therap Adv Gastroenterol (Therapeutic advances in gastroenterology)
[2019, 12:1756284819864549]

Cited: 1 time

View full text PDF listing >>



Esophageal acid sensitivity in patients with gastroesophageal reflux disease: Does esophageal hypomotility matter?

Ming-Wun Wong, Jui-Sheng Hung, Wei-Yi Lei, Tso-Tsai Liu, Chih-Hsun Yi, Chien-Lin Chen,

<h4>Background/aim</h4>Esophageal acid sensitivity plays a role in symptomatic manifestation of gastroesophageal reflux disease (GERD). Esophageal hypomotility is common in patients with GERD. We aimed to determine whether esophageal acid sensitivity may differ between patients with and without esophageal hypomotility.<h4>Methods</h4>We prospectively enrolled 41 consecutive patients (10 females, mean age 53 years, range ... Read more >>

Neurogastroenterol Motil (Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society)
[2019, 31(11):e13700]

Cited: 0 times

View full text PDF listing >>



Does prucalopride reduce the dose of sodium phosphate in bowel preparation? A single-blind, randomized, and prospective study.

Jui-Sheng Hung, Chih-Hsun Yi, Tso-Tsai Liu, Wei-Yi Lei, Ming-Wun Wong, Chien-Lin Chen,

<h4>Objective</h4>Sodium phosphate solution (NaP) in oral form is well known and frequently used for good quality bowel cleansing before a colonoscopy, but it carries the potential risk of electrolyte disturbance and dehydration. Prucalopride mitigates severe constipation by promoting colon motility. We evaluated the hypothesis that prucalopride plus one single dose ... Read more >>

J Dig Dis (Journal of digestive diseases)
[2019, 20(6):294-300]

Cited: 0 times

View full text PDF listing >>



Evaluation of Baseline Impedance During Water-perfused High Resolution Impedance Manometry in Patients With Symptomatic GERD.

Jui-Sheng Hung, Ming-Wun Wong, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Chien-Lin Chen,

<h4>Goals</h4>We aimed to investigate the hypothesis whether baseline impedance measured during water-perfused high resolution impedance manometry (HRIM) can help discriminate patients with reflux symptoms from the controls and predict the response to the proton pump inhibitors (PPIs).<h4>Background/aim</h4>Baseline impedance measured during solid-state HRIM can reliably discriminate patients with gastroesophageal reflux disease ... Read more >>

J Clin Gastroenterol (Journal of clinical gastroenterology)
[2019, 53(5):350-354]

Cited: 0 times

View full text PDF listing >>



Clinical and psychological characteristics in gastroesophageal reflux disease patients overlapping with laryngopharyngeal reflux symptoms.

Ming-Wun Wong, Ming-Jong Bair, Wei-Chuan Chang, Ching-Sheng Hsu, Jui-Sheng Hung, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Michael F Vaezi, C Prakash Gyawali, Chien-Lin Chen,

<h4>Background and aim</h4>Laryngopharyngeal reflux (LPR) defined as reflux of gastric content reaching above the upper esophageal sphincter is frequently found in patients with gastroesophageal reflux disease (GERD). This study aimed to investigate clinical and psychological differences between GERD patients with or without LPR symptoms.<h4>Methods</h4>This study enrolled 303 consecutive patients with ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2019, 34(10):1720-1726]

Cited: 1 time

View full text PDF listing >>



Similarities and differences between IBS-C and FC with regards to symptomatology, sleep quality and psychological attributes.

Hung-Da Chen, Ming-Jong Bair, Wei-Chuan Chang, Ching-Sheng Hsu, Ming-Wun Wong, Jui-Sheng Hung, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Chien-Lin Chen,

<h4>Background</h4>Irritable bowel syndrome (IBS) and functional constipation (FC) are highly prevalent in the general population and have significant symptom overlap, while the clinical associations and psychological links between IBS and FC remains poorly understood. We aimed to compare the clinical, metabolic and psychological factors between patients with FC patients and ... Read more >>

J Formos Med Assoc (Journal of the Formosan Medical Association = Taiwan yi zhi)
[2020, 119(1 Pt 1):75-80]

Cited: 0 times

View full text PDF listing >>



Effects of esophageal acid infusion vs mosapride on distension-induced secondary peristalsis in humans.

Wei-Yi Lei, Jui-Sheng Hung, Chih-Hsun Yi, Tso-Tsai Liu, Ming-Wun Wong, Chien-Lin Chen,

Secondary peristalsis contributes to the clearance of the refluxate from the esophagus. Acute administration of 5-hydroxytryptamine 4 (5-HT<sub>4</sub> ) receptors agonist, mosapride or esophageal infusion of hydrochloric acid (HCl) facilitates secondary peristalsis. The aim of this study was to determine whether esophageal acid infusion and administration of mosapride had different ... Read more >>

Kaohsiung J Med Sci (The Kaohsiung journal of medical sciences)
[2019, 35(5):310-314]

Cited: 0 times

View full text PDF listing >>



Impact of concomitant dyspepsia and irritable bowel syndrome on symptom burden in patients with gastroesophageal reflux disease.

Wei-Yi Lei, Wei-Chuan Chang, Shu-Hui Wen, Ming-Wun Wong, Jui-Sheng Hung, Chih-Hsun Yi, Tso-Tsai Liu, Ching-Sheng Hsu, William C Orr, Michael F Vaezi, Fabio Pace, Tsung-Cheng Hsieh, Chien-Lin Chen,

<h4>Background</h4>Patients with gastroesophageal reflux disease (GERD) frequently report symptoms like dyspepsia or/and irritable bowel syndrome (IBS). The aim of the study was to investigate the impact of symptom overlap on GERD symptom burden. We also investigate whether GERD overlapping dyspepsia or/and IBS would have different clinical and psychological features as ... Read more >>

J Formos Med Assoc (Journal of the Formosan Medical Association = Taiwan yi zhi)
[2019, 118(4):797-806]

Cited: 2 times

View full text PDF listing >>



Impact of vegan diets on gut microbiota: An update on the clinical implications.

Ming-Wun Wong, Chih-Hsun Yi, Tso-Tsai Liu, Wei-Yi Lei, Jui-Sheng Hung, Chin-Lon Lin, Shinn-Zong Lin, Chien-Lin Chen,

Numerous studies indicate that microbiota plays an important role in human health. Diet is a factor related to microbiota which also influences human health. The relationships between diet, microbiota, and human health are complex. This review focuses on the current literature on vegan diets and their unique impact on gut ... Read more >>

Tzu Chi Med J (Tzu chi medical journal)
[2018, 30(4):200-203]

Cited: 8 times

View full text PDF listing >>



Gamma-aminobutyric acid receptor type B agonist baclofen inhibits acid-induced excitation of secondary peristalsis but not heartburn sensation.

Ming-Wun Wong, Jui-Sheng Hung, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Chien-Lin Chen,

<h4>Background and aim</h4>Acute esophageal acid infusion promotes distension-induced secondary peristalsis. The gamma-aminobutyric acid receptor type B (GABA-B) receptors activation inhibits secondary peristalsis. This study aimed to test the hypothesis whether acid excitation of secondary peristalsis can be influenced by baclofen.<h4>Methods</h4>Secondary peristalsis was performed with intra-esophageal slow and rapid air injections ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2019, 34(2):370-375]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

3.801 s