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Photovoltaic modulation of ferromagnetism within a FM metal/P-N junction Si heterostructure.

Yifan Zhao, Shishun Zhao, Lei Wang, Shiping Wang, Yujing Du, Yanan Zhao, Shengye Jin, Tai Min, Bian Tian, Zhuangde Jiang, Ziyao Zhou, Ming Liu,

Obtaining small, fast, and energy-efficient spintronic devices requires a new way of manipulating spin states in an effective manner. Here, a prototype photovoltaic spintronic device with a p-n junction Si wafer is proposed which generates photo-induced electrons and changes the ferromagnetism by interfacial charge doping. A ferromagnetic resonance field change ... Read more >>

Nanoscale (Nanoscale)
[2021, 13(1):272-279]

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Occurrence, molecular characterization, and antimicrobial susceptibility of Yersinia enterocolitica isolated from retail food samples in China

Juan Wang, Ming Liu, Huixian Wang, Qingping Wu, Yu Ding, Tianxiang Xu, Guoxiang Ma, Yueming Zhong, Jumei Zhang, Moutong Chen, Liang Xue, Qinghua Ye, Haiyan Zeng, Xiaojuan Yang, Runshi Yang,

Yersinia enterocolitica (Y. enterocolitica) is an important foodborne pathogen that causes gastrointestinal syndromes. The objectives of this study were to examine the incidence of Y. enterocolitica strains in food samples in China and determine their genotypes, in addition to assessing their antimicrobial resistance and pathogenic potential. From June 2015 to ... Read more >>

Lebensm Wiss Technol (Lebensmittel-Wissenschaft + [i.e. und] Technologie.)
[2021, 150:Not Available]

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Non-programmable cryopreservation of sperm from industrial-farmed Murray cod (Maccullochella p peelii)

Meijian Liu, Sheng Yuan, Ziming Zhao, Ming Liu, Apeng Lin, Qingli Gong,

The high price of larvae is a major constraint for the expansion of Murray cod (Maccullochella p peelii) aquaculture. Sperm cryopreservation creates a ready supply of sperm for the production of larvae, reduces the number of males required by hatcheries and contributes to preserving desirable genetic traits for breeding programmes. ... Read more >>

Aquaculture (Aquaculture (Amsterdam, Netherlands))
[2021, 541:Not Available]

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The SEED study of dorzagliatin in drug-naïve patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, phase 3 trial

Li Chen, Dalong Zhu, Xiaoying Li, Wenying Yang, Jianhua Ma, Jiao’e Zeng, Shenglian Gan, Xiaolin Dong, Jing Yang, Xiaohong Lin, Hanqing Cai, Weihong Song, Xuefeng Li, Keqin Zhang, Qiu Zhang, Yibing Lu, Ruifang Bu, Huige Shao, Guixia Wang, Guoyue Yuan, Xingwu Ran, Lin Liao, Wenjuan Zhao, Li Sun, Lixin Shi, Zhaoshun Jiang, Yaoming Xue, Hongwei Jiang, Quanmin Li, Zongbao Li, Maoxiong Fu, Zerong Liang, Lian Guo, Ming Liu, Chun Xu, Wenhui Li, Xuefeng Yu, Guijun Qin, Zhou Yang, Benli Su, Longyi Zeng, Houfa Geng, Yongquan Shi, Yu Zhao, Yi Zhang,

Improvement of glucose and insulin sensitivity remains an unmet medical need in diabetes management, in which the underlying cause of type 2 diabetes(T2D) was not well addressed by current treatment. We report the findings of a randomized, double-blind, placebo-controlled, phase 3 clinical trial (NCT03173391) to evaluate the efficacy and safety ... Read more >>

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HNRNPU-AS1 regulates cell proliferation and apoptosis via miR-205-5p/AXIN2 axis and Wnt/β-catenin signaling pathway in cervical cancer.

Zhaoyuan Niu, Fengling Wang, Shihui Lv, Yingpin Lv, Ming Liu, Lei Fu, Yushuang Yao, Lingzhi Wang, Wei Lin, Fang Yuan,

Long non-coding RNAs (lncRNAs) have key functions in modulating cervical cancer (CC) genesis and progression. This work focused on exploring lncRNA HNRNPU-AS1's function in CC and the underlying mechanism. HNRNPU-AS1, AXIN2 and miR-205-5p levels in CC cases were measured through RT-qPCR. Relationship between miR-205-5p and AXIN2 or HNRNPU-AS1 was validated ... Read more >>

Mol Cell Biol (Molecular and cellular biology)
[2021, :MCB0011521]

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Identification of a Novel Plasmid-Mediated Carbapenemase-Encoding Gene, blaVMB-2, in Vibrio diabolicus.

Ming Liu, Wenhui Zhang, Kai Peng, Zhiqiang Wang, Ruichao Li,

Here, we characterized a carbapenem-resistant Vibrio diabolicus strain of shrimp origin with various experiments and bioinformatics analysis. A novel metallo-β-lactamase (MBL) gene, <i>bla</i><sub>VMB-2</sub>, that confers resistance to β-lactams, including meropenem and cephalosporins, was identified on a plasmid-borne composite transposon, IS<i>Shfr9</i>-IS<i>CR1</i>-<i>bla</i><sub>VMB-2</sub>-<i>bla</i><sub>CARB-12</sub>-<i>aadA1-</i>IS<i>Shfr9</i>, which is capable of generating a <i>bla</i><sub>VMB-2</sub>-bearing circular intermediate. IS<i>Shfr9</i> ... Read more >>

Antimicrob Agents Chemother (Antimicrobial agents and chemotherapy)
[2021, 65(8):e0020621]

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Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.

Hong Kuang, Tianhong Wang, Lei Liu, Chunhai Tang, Tao Li, Ming Liu, Tianping Wang, Weiying Zhong, Yunyan Wang,

Post-subarachnoid hemorrhage (SAH) survivors experience severe neurological disability. Previous studies implicate that ferroptosis is involved in SAH. Ferroptosis is an iron-dependent form of regulated cell death caused by the accumulation of lipid peroxidation. However, the role and the mechanism of ferroptosis in SAH are still uncertain and need further study. ... Read more >>

Neurosci Lett (Neuroscience letters)
[2021, :136134]

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Machine learning prediction of pyrolytic gas yield and compositions with feature reduction methods: Effects of pyrolysis conditions and biomass characteristics.

Qinghui Tang, Yingquan Chen, Haiping Yang, Ming Liu, Haoyu Xiao, Shurong Wang, Hanping Chen, Salman Raza Naqvi,

This study aimed to utilize machine learning algorithems combined with feature reduction for predicting pyrolytic gas yield and compositions based on pyrolysis conditions and biomass characteristics. To this end, random forest (RF) and support vector machine (SVM) was introduced and compared. The results suggested that six features were adequate to ... Read more >>

Bioresour Technol (Bioresource technology)
[2021, 339:125581]

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Conductive Ionenes Promote Interfacial Self-Doping for Efficient Organic Solar Cells.

Ming Liu, Mengyang Li, Yufeng Jiang, Zaifei Ma, Duanzijing Liu, Zhongjie Ren, Thomas P Russell, Yao Liu,

Conductive ionenes were synthesized by integrating the electron donor dialkoxynaphthalene (DAN) with the electron acceptor naphthalene diimide (NDI) using the Menshutkin reaction. The crystallinity and morphology of the films of these polymers can be optimized by varying the DAN-to-NDI ratio. These ionenes show strong charge transfer from DAN to NDI, ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, :]

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Serum neurofilament light chain or glial fibrillary acidic protein in the diagnosis and prognosis of brain metastases.

Xinqing Lin, Tingting Lu, Haiyi Deng, Chunxin Liu, Yilin Yang, Tao Chen, Yinyin Qin, Xiaohong Xie, Zhanhong Xie, Ming Liu, Ming Ouyang, Shiyue Li, Yong Song, Nanshan Zhong, Wei Qiu, Chengzhi Zhou,

<h4>Introduction</h4>Brain metastases (BM) remains the most cumbersome disease burden in patients with lung cancer. This study aimed to investigate whether serum brain injury biomarkers can indicate BM, to further establish related diagnostic models, or to predict prognosis of BM.<h4>Materials and methods</h4>This was a prospective study of patients diagnosed with lung ... Read more >>

J Neurol (Journal of neurology)
[2021, :]

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Vasal vessel-sparing microsurgical single-armed vasoepididymostomy to epididymal obstructive azoospermia: A retrospective control study.

Peng Li, Nachuan Liu, Erlei Zhi, Chencheng Yao, Huixing Chen, Ruhui Tian, Yuhua Huang, Liangyu Zhao, Chao Yang, Jingpeng Zhao, Chenkun Shi, Ming Liu, Bo Wang, Huirong Chen, Zheng Li, Shujie Xia,

This study aimed to evaluate the efficacy and safety of vasal vessel-sparing modified single-armed 2-suture longitudinal intussusception vasoepididymostomy (SA-LIVE) to epididymal obstructive azoospermia patients. Forty consecutive epididymal obstructive azoospermia cases, who underwent microsurgical vasoepididymostomy in Shanghai General Hospital from January 2019 to October 2019, were included in this study. Twenty ... Read more >>

Andrologia (Andrologia)
[2021, :e14133]

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Distinct states of proinsulin misfolding in MIDY.

Leena Haataja, Anoop Arunagiri, Anis Hassan, Kaitlin Regan, Billy Tsai, Balamurugan Dhayalan, Michael A Weiss, Ming Liu, Peter Arvan,

A precondition for efficient proinsulin export from the endoplasmic reticulum (ER) is that proinsulin meets ER quality control folding requirements, including formation of the Cys(B19)-Cys(A20) "interchain" disulfide bond, facilitating formation of the Cys(B7)-Cys(A7) bridge. The third proinsulin disulfide, Cys(A6)-Cys(A11), is not required for anterograde trafficking, i.e., a "lose-A6/A11" mutant [Cys(A6), ... Read more >>

Cell Mol Life Sci (Cellular and molecular life sciences : CMLS)
[2021, :]

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Clinical observation and finite element analysis of cannulated screw internal fixation in the treatment of femoral neck fracture based on different reduction quality.

Gan Zhao, Ming Liu, Bin Li, Haizhong Sun, Biaofang Wei,

<h4>Objective</h4>Femoral neck fracture is one of the most common bone types. The effect of reduction quality on hip joint function and complications after screw internal fixation is not fully understood. To investigate the clinical efficacy and mechanical mechanism of positive buttress, anatomical reduction, and negative buttress in the treatment of ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):450]

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Levo-tetrahydropalmatine: A new potential medication for methamphetamine addiction and neurotoxicity.

Lian Liu, Ming Liu, Wei Zhao, Yuan-Ling Zhao, Yun Wang,

Levo-tetrahydropalmatine (l-THP) is mainly derived from the dried tuber of the Papaveraceae plant Corydalis, also called Corydalis B, which is a drug with analgesic, hypnotic, sedative and other effects. Methamphetamine (METH) belongs to the central nervous stimulant and is a highly addictive drug. It is an urgent problem to study ... Read more >>

Exp Neurol (Experimental neurology)
[2021, 344:113809]

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Genotype-phenotype correlation of CACNA1A variants in children with epilepsy.

Xueyang Niu, Ying Yang, Yi Chen, Miaomiao Cheng, Ming Liu, Changhong Ding, Xiaojuan Tian, Zhixian Yang, Yuwu Jiang, Yuehua Zhang,

<h4>Aim</h4>To explore the genotypes and phenotypes of CACNA1A variants in children with epilepsy.<h4>Method</h4>Eighteen children (six males, 12 females) with CACNA1A variants were identified using next-generation sequencing.<h4>Results</h4>There were 14 missense variants, two nonsense variants, one frameshift variant, and one splice site variant. Sixteen variants were de novo. Age at seizure onset ... Read more >>

Dev Med Child Neurol (Developmental medicine and child neurology)
[2021, :]

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Is there a Trade-off between Economy and Task Goal Variability in Transfemoral Amputee Gait?

I-Chieh Lee, Bretta Fylstra, Ming Liu, Tommaso Lenzi, He Huang,

<h4>Background: </h4> Energy cost minimization has been widely accepted to regulate gait. Optimization principles have been frequently used to explain how individuals adapt their gait pattern. However, there have been rare attempts to account for the role of variability in this optimization process. Motor redundancy can enable individuals to perform ... Read more >>

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Hydroxyphenyl Butanone Induces Cell Cycle Arrest through Inhibition of GSK3β in Colorectal Cancer.

Songyan Zhang, Yunfeng Wang, Haopeng Zhang, Chengming Sun, Shuwei Dang, Ming Liu,

<h4>Background</h4>Colorectal cancer (CRC) is among the top three gastrointestinal malignancy in morbidity and mortality. The abnormal activation of Wnt/<i>β</i>-catenin pathway is considered to be a key factor in the occurrence and development of CRC. Novel inhibitor discovery against key factor in WNT pathway is important for CRC treatment and prevention.<h4>Methods</h4>Cell ... Read more >>

Biomed Res Int (BioMed research international)
[2021, 2021:9981815]

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ALKBH5-Mediated m6A Modification of LncRNA KCNQ1OT1 Triggers the Development of LSCC via Upregulation of HOXA9

Yushan Li, Bingrui Yan, Xin Wang, Qiuying Li, Xuan Kan, Jingting Wang, Yanan Sun, Peng Wang, Linli Tian, Ming Liu,

<h4>Background: </h4> RNA epigenetic modification is the chemical basis of RNA-regulated gene expression, of which N6-methyladenosine (m6A) is one of the most common post-transcriptional modifications in mRNA. More and more studies show that m6A modification is involved in the development of complex human diseases, especially in the development of cancer. ... Read more >>

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MiR-135-5p Alleviates Bone Cancer Pain by Regulating Astrocyte-Mediated Neuroinflammation in Spinal Cord through JAK2/STAT3 Signaling Pathway.

Ming Liu, Xuefeng Cheng, Hong Yan, Jingli Chen, Caihua Liu, Zhonghui Chen,

Bone cancer pain (BCP) was associated with microRNA dysregulation. In this study, we intended to clarify the potential role of miR-135-5p in a BCP mouse model, which was established by tumor cell implantation (TCI) in the medullary cavity of the mouse femur. The BCP-related behaviors were tested, including the paw ... Read more >>

Mol Neurobiol (Molecular neurobiology)
[2021, :]

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Predictors for intraoperative heart failure in children undergoing foreign-body removal.

Xianyi Yao, Lei Zhang, Guangyu Zhao, Haifeng Pang, Tingting Li, Xiao Han, Ming Liu,

<h4>Abstract</h4>This study aimed to determine the predictors for intraoperative heart failure (HF) in children undergoing foreign-body removal. The clinical data of all children with tracheobronchial foreign-body aspiration admitted to the First, Second, and Fourth Affiliated Hospitals of Harbin Medical University between January 1996 and September 2018 were analyzed. The variables ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(28):e26626]

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Liver Fibrosis Indices Associated with Substantial Hematoma Expansion in Chinese Patients with Primary Intracerebral Hemorrhage

Huan Wang, Jiongxing Wu, Xue Yang, Junfeng Liu, Wendan Tao, Zilong Hao, Bo Wu, Ming Liu, Shihong Zhang, Deren Wang,

<h4>Background: </h4> Whether liver fibrosis is associated with increased risk for substantial hematoma expansion (HE) after intracerebral hemorrhage (ICH) is still uncertain. We evaluated the association between various liver fibrosis indices and substantial HE in a Chinese population with primary ICH. <h4>Methods: </h4> Primary ICH patients admitted to West China ... Read more >>

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TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer.

Tao Gui, Ming Liu, Bing Yao, Haiqin Jiang, Dongjun Yang, Qixiang Li, Xiangwei Zeng, Ying Wang, Jian Cao, Yexuan Deng, Xinyu Li, Peipei Xu, Liqin Zhou, Dake Li, Zhihui Wang, Ke Zen, David C S Huang, Bing Chen, Guiping Wan, Quan Zhao,

Endometrial cancer (EC) is the most common gynecological malignancy worldwide. However, the molecular mechanisms underlying EC progression are still largely unknown, and chemotherapeutic options for EC patients are currently very limited. In this study, we found that histone methyltransferase EZH2 and DNA methyltransferase DNMT3B were upregulated in EC samples from ... Read more >>

Cell Death Differ (Cell death and differentiation)
[2021, :]

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Characterization of top 100 researches on e-waste based on bibliometric analysis.

Xianghong Chen, Ming Liu, Bo Xie, Liwei Chen, Jingting Wei,

With rapid development of energy, information, and communication technology, e-waste problem has become one of the global issues to be settled urgently. The main features on publication years, journals, countries and institutions, authors, keywords, and content types of the 100 most-cited articles on e-waste had been unfolded in this research. ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2021, :]

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Developing a nomogram for predicting intravesical recurrence after radical nephroureterectomy: a retrospective cohort study of mainland Chinese patients.

Shicong Lai, Xingbo Long, Pengjie Wu, Jianyong Liu, Samuel Seery, Huimin Hou, Ming Liu, Yuan Li, Jianye Wang,

<h4>Objective</h4>To evaluate the role of Ki-67 in predicting subsequent intravesical recurrence following radical nephroureterectomy and to develop a predictive nomogram for upper tract urothelial carcinoma patients.<h4>Methods</h4>This retrospective analysis involved 489 upper tract urothelial carcinoma patients who underwent radical nephroureterectomy with bladder cuff excision. The data set was randomly split into ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(7):1132-1141]

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Prognostic and Therapeutic Value of Apolipoprotein A and a New Risk Scoring System Based on Apolipoprotein A and Adenosine Deaminase in Chronic Lymphocytic Leukemia.

Xiaoya Yun, Xiang Sun, Xinting Hu, Huimin Zhang, Zixun Yin, Xin Zhang, Ming Liu, Ya Zhang, Xin Wang,

Lipid metabolism is related to lymphomagenesis, and is a novel therapeutic target in some hematologic tumors. Apolipoprotein A (ApoA), the major protein of high-density lipoprotein (HDL), plays a crucial role in lipid transportation and protecting against cardiovascular disease, and takes effect on anti-inflammation and anti-oxidation. It is correlated with the ... Read more >>

Front Oncol (Frontiers in oncology)
[2021, 11:698572]

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