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Author Minal Amin

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Late-onset Hearing Loss From Congenital Cytomegalovirus Infection After Newborn Period in a Highly Immune Population in China.

Chengbin Wang, Xiaolin Liu, Shiwen Wang, Wenqiang Zhang, Haiyan Wang, Wei Ma, Xiangxin Meng, Xingqu Xu, Zhan Li, Qiang Pan, Shuxia Zhang, Ping Wang, Qian Lin, Xiaofang Wang, Minal Amin, Sheila Dollard, Aiqiang Xu, Winnie Chung,

After following 141 children with likely asymptomatic congenital cytomegalovirus infection in a highly immune population in China, four children (2.8%) were found to have late-onset hearing loss. No maternal or childhood factors, except higher saliva cytomegalovirus viral load at birth (P = 0.03), were associated with increased risk of developing ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(1):70-73]

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Transmission of SARS-CoV-2 from Children and Adolescents

Victoria Chu, Anna Yousaf, Karen Chang, Noah Schwartz, Clinton McDaniel, Christine Szablewski, Marie Brown, Kathryn Winglee, Scott Lee, Zhaohui Cui, Adebola Adebayo, Tiffiany Aholou, Minal Amin, Peter Aryee, Cindy Castaneda, Trudy Chambers, Amy Fleshman, Christin Goodman, Tony Holmes, Asha Ivey-Stephenson, Emiko Kamitani, Susan Katz, Jennifer Knapp, Maureen Kolasa, Maranda Lumsden, Erin Mayweather, Asfia Mohammed, Anne Moorman, Alpa Patel-Larson, Lara Perinet, Mark Pilgard, Deirdre Pratt, Shanica Railey, Jaina Shah, Dawn Tuckey, Emilio Dirlikov, Dale Rose, Julie Villanueva, Alicia Fry, Aron Hall, Hannah Kirking, Jacqueline Tate, Cherie Drenzek, Tatiana Lanzieri, Rebekah Stewart,

A better understanding of SARS-CoV-2 transmission from children and adolescents is crucial for informing public health mitigation strategies. We conducted a retrospective cohort study among household contacts of primary cases defined as children and adolescents aged 7⍰19 years with laboratory evidence of SARS-CoV-2 infection acquired during an overnight camp outbreak. ... Read more >>

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Donor-derived human herpesvirus 8 and development of Kaposi sarcoma among 6 recipients of organs from donors with high-risk sexual and substance use behavior.

Sheila C Dollard, Pallavi Annambhotla, Phili Wong, Katherine Meneses, Minal M Amin, Ricardo M La Hoz, Erika D Lease, Maria Budev, Andrea Valeria Arrossi, Sridhar V Basavaraju, Christie P Thomas,

Kaposi sarcoma (KS) can develop following organ transplantation through reactivation of recipient human herpesvirus 8 (HHV-8) infection or through donor-derived HHV-8 transmission. We describe 6 cases of donor-derived HHV-8 infection and KS investigated from July 2018 to January 2020. Organs from 6 donors, retrospectively identified as HHV-8-positive, with a history ... Read more >>

Am J Transplant (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons)
[2020, :]

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Update: Characteristics of Patients in a National Outbreak of E-cigarette, or Vaping, Product Use-Associated Lung Injuries - United States, October 2019.

Erin D Moritz, Lauren B Zapata, Akaki Lekiachvili, Emily Glidden, Francis B Annor, Angela K Werner, Emily N Ussery, Michelle M Hughes, Anne Kimball, Carla L DeSisto, Brandon Kenemer, Mays Shamout, Macarena C Garcia, Sarah Reagan-Steiner, Emily E Petersen, Emily H Koumans, Matthew D Ritchey, Brian A King, Christopher M Jones, Peter A Briss, Lisa Delaney, Anita Patel, Kara D Polen, Katie Sives, Dana Meaney-Delman, Kevin Chatham-Stephens, , ,

CDC, the Food and Drug Administration, state and local health departments, and other public health and clinical stakeholders are investigating a national outbreak of electronic-cigarette (e-cigarette), or vaping, product use-associated lung injury (EVALI) (1). As of October 22, 2019, 49 states, the District of Columbia (DC), and the U.S. Virgin ... Read more >>

MMWR Morb Mortal Wkly Rep (MMWR. Morbidity and mortality weekly report)
[2019, 68(43):985-989]

Cited: 21 times

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Update: Interim Guidance for Health Care Providers Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use Associated Lung Injury - United States, October 2019.

David A Siegel, Tara C Jatlaoui, Emily H Koumans, Emily A Kiernan, Mark Layer, Jordan E Cates, Anne Kimball, David N Weissman, Emily E Petersen, Sarah Reagan-Steiner, Shana Godfred-Cato, Danielle Moulia, Erin Moritz, Jonathan D Lehnert, Jane Mitchko, Joel London, Sherif R Zaki, Brian A King, Christopher M Jones, Anita Patel, Dana Meaney Delman, Ram Koppaka, , ,

CDC, the Food and Drug Administration (FDA), state and local health departments, and public health and clinical partners are investigating a multistate outbreak of lung injury associated with the use of electronic cigarette (e-cigarette), or vaping, products. In late August, CDC released recommendations for health care providers regarding e-cigarette, or ... Read more >>

MMWR Morb Mortal Wkly Rep (MMWR. Morbidity and mortality weekly report)
[2019, 68(41):919-927]

Cited: 30 times

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Characteristics of a Multistate Outbreak of Lung Injury Associated with E-cigarette Use, or Vaping - United States, 2019.

Cria G Perrine, Cassandra M Pickens, Tegan K Boehmer, Brian A King, Christopher M Jones, Carla L DeSisto, Lindsey M Duca, Akaki Lekiachvili, Brandon Kenemer, Mays Shamout, Michael G Landen, Ruth Lynfield, Isaac Ghinai, Amy Heinzerling, Nathaniel Lewis, Ian W Pray, Lauren J Tanz, Anita Patel, Peter A Briss, ,

Electronic cigarettes (e-cigarettes), also called vapes, e-hookas, vape pens, tank systems, mods, and electronic nicotine delivery systems (ENDS), are electronic devices that produce an aerosol by heating a liquid typically containing nicotine, flavorings, and other additives; users inhale this aerosol into their lungs (1). E-cigarettes also can be used to ... Read more >>

MMWR Morb Mortal Wkly Rep (MMWR. Morbidity and mortality weekly report)
[2019, 68(39):860-864]

Cited: 26 times

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The impact of maternal HIV and malaria infection on the prevalence of congenital cytomegalovirus infection in Western Kenya.

Nancy A Otieno, Bryan O Nyawanda, Fredrick Otiato, Martina Oneko, Minal M Amin, Michael Otieno, Daniel Omollo, Meredith McMorrow, Sandra S Chaves, Sheila C Dollard, Tatiana M Lanzieri,

<h4>Background</h4>Data on congenital cytomegalovirus (CMV) infection in Africa are limited.<h4>Objective</h4>To describe the prevalence of congenital CMV infection in a population with high prevalence of maternal HIV and malaria infection in western Kenya.<h4>Study design</h4>We screened newborns for CMV by polymerase chain reaction assay of saliva swabs and dried blood spots (DBS), ... Read more >>

J Clin Virol (Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology)
[2019, 120:33-37]

Cited: 0 times

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CMV on surfaces in homes with young children: results of PCR and viral culture testing.

Minal M Amin, Jennifer D Stowell, William Hendley, Philip Garcia, D Scott Schmid, Michael J Cannon, Sheila C Dollard,

<h4>Background</h4>Caring for young children is a known risk factor for cytomegalovirus (CMV) infection mainly through exposure to their saliva and urine. In a previous study, 36 CMV-seropositive children 2 mo. to 4 years old were categorized as CMV shedders (n = 23) or non-shedders (n = 13) based on detection of CMV DNA in their ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2018, 18(1):391]

Cited: 0 times

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Urinary Cytomegalovirus Shedding in the United States: The National Health and Nutrition Examination Surveys, 1999-2004.

Minal M Amin, Stephanie R Bialek, Sheila C Dollard, Chengbin Wang,

<h4>Background</h4>There are no data on the prevalence of cytomegalovirus (CMV) shedding from a representative sample of the US population. This information is critical for understanding and preventing CMV.<h4>Methods</h4>We tested urine specimens from CMV immunoglobulin (Ig) G-positive participants aged 6-49 years in 3 racial/ethnic groups from the National Health and Nutrition ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2018, 67(4):587-592]

Cited: 6 times

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Viral Loads in Congenital Cytomegalovirus Infection From a Highly Immune Population.

Aiqiang Xu, Shiwen Wang, Wenqiang Zhang, Xiaofang Wang, Tongzhan Wang, Xiaolin Liu, Haiyan Wang, Wei Ma, Minal Amin, Sheila Dollard, Chengbin Wang,

Among newborns with congenital cytomegalovirus (CMV) infection from China, there was no difference in CMV viral load in saliva specimens dried and stored at room temperature compared with those kept wet and stored cold, even after longer storage time for the former than the later (74 vs 58 days, P ... Read more >>

J Pediatric Infect Dis Soc (Journal of the Pediatric Infectious Diseases Society)
[2018, 7(3):e160-e162]

Cited: 1 time

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Using theory-based messages to motivate U.S. pregnant women to prevent cytomegalovirus infection: results from formative research.

Denise M Levis, Christina L Hillard, Simani M Price, Erika Reed-Gross, Erika Bonilla, Minal Amin, Jennifer D Stowell, Rebekah Clark, Delaney Johnson, Karen Mask, Cynthia Carpentieri, Michael J Cannon,

An estimated 1 in 150 infants is born each year with congenital cytomegalovirus (CMV); nearly 1 in 750 suffers permanent disabilities. Congenital CMV is the result of a pregnant woman becoming infected with CMV. Educating pregnant women about CMV is currently the best approach to prevention. Limited research is available ... Read more >>

BMC Womens Health (BMC women's health)
[2017, 17(1):131]

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Cohort study on maternal cytomegalovirus seroprevalence and prevalence and clinical manifestations of congenital infection in China.

Shiwen Wang, Tongzhan Wang, Wenqiang Zhang, Xiaolin Liu, Xiaofang Wang, Haiyan Wang, Xiaozhou He, Shunxian Zhang, Shuhui Xu, Yang Yu, Xingbing Jia, Maolin Wang, Aiqiang Xu, Wei Ma, Minal M Amin, Stephanie R Bialek, Sheila C Dollard, Chengbin Wang,

Congenital cytomegalovirus (CMV) infection is the leading viral cause of birth defects and developmental disabilities in developed countries. However, CMV seroprevalence and burden of congenital CMV infection are not well defined in China.Cohort of newborns from 5 birthing hospitals in 2 counties of Shandong Province, China, were enrolled from March ... Read more >>

Medicine (Baltimore) (Medicine)
[2017, 96(5):e6007]

Cited: 12 times

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Cytomegalovirus IgM Seroprevalence among Women of Reproductive Age in the United States.

Chengbin Wang, Sheila C Dollard, Minal M Amin, Stephanie R Bialek,

Cytomegalovirus (CMV) IgM indicates recent active CMV infection. CMV IgM seroprevalence is a useful marker for prevalence of transmission. Using data from the National Health and Nutrition Examination Survey (NHANES) III 1988-1994, we present estimates of CMV IgM prevalence by race/ethnicity, provide a comparison of IgM seroprevalence among all women ... Read more >>

PLoS One (PloS one)
[2016, 11(3):e0151996]

Cited: 7 times

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Cytomegalovirus IgG Level and Avidity in Breastfeeding Infants of HIV-Infected Mothers in Malawi.

Athena P Kourtis, Jeffrey Wiener, Tiffany S Chang, Sheila C Dollard, Minal M Amin, Sascha Ellington, Dumbani Kayira, Charles van der Horst, Denise J Jamieson,

Cytomegalovirus (CMV) infection is common among infants of HIV-infected mothers in resource-limited settings. We examined the prevalence and timing of infant CMV infection during the first year of life using IgG antibody and avidity among HIV-exposed infants in Malawi and correlated the results with the presence of detectable CMV DNA ... Read more >>

Clin Vaccine Immunol (Clinical and vaccine immunology : CVI)
[2015, 22(12):1222-1226]

Cited: 3 times

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Effect of cytomegalovirus infection on breastfeeding transmission of HIV and on the health of infants born to HIV-infected mothers.

Tiffany S Chang, Jeffrey Wiener, Sheila C Dollard, Minal M Amin, Sascha Ellington, Charles Chasela, Dumbani Kayira, Gerald Tegha, Deborah Kamwendo, Denise J Jamieson, Charlie van der Horst, Athena P Kourtis, ,

<h4>Background</h4>Cytomegalovirus (CMV) infection can be acquired in utero or postnatally through horizontal transmission and breastfeeding. The effect of postnatal CMV infection on postnatal HIV transmission is unknown.<h4>Methods</h4>The Breastfeeding, Antiretrovirals and Nutrition study, conducted in Malawi, randomized 2369 mothers and their infants to three antiretroviral prophylaxis arms - mother (triple regimen), ... Read more >>

AIDS (AIDS (London, England))
[2015, 29(7):831-836]

Cited: 15 times

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Cytomegalovirus viral and antibody correlates in young children.

Sheila C Dollard, Harry Keyserling, Kay Radford, Minal M Amin, Jennifer Stowell, Jörn Winter, D Scott Schmid, Michael J Cannon, Terri B Hyde,

<h4>Background</h4>Young, healthy children shedding cytomegalovirus (CMV) in urine and saliva appear to be the leading source of CMV in primary infection of pregnant women.<h4>Findings</h4>We screened 48 children 6 months - 5 years old for CMV IgG and measured levels of CMV IgG, IgM and IgG avidity antibodies, frequency of CMV ... Read more >>

BMC Res Notes (BMC research notes)
[2014, 7:776]

Cited: 7 times

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Seroprevalence of cytomegalovirus among children 1 to 5 years of age in the United States from the National Health and Nutrition Examination Survey of 2011 to 2012.

Tatiana M Lanzieri, Deanna Kruszon-Moran, Minal M Amin, Stephanie R Bialek, Michael J Cannon, Margaret D Carroll, Sheila C Dollard,

Cytomegalovirus (CMV) seroprevalence among U.S. children 1 to 5 years old was assessed in the National Health and Nutrition Examination Survey of 2011 to 2012. The overall seroprevalence (95% confidence interval) of IgG was 20.7% (14.4 to 28.2%), that of IgM was 1.1% (0.4 to 2.4%), and that of low ... Read more >>

Clin Vaccine Immunol (Clinical and vaccine immunology : CVI)
[2015, 22(2):245-247]

Cited: 15 times

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1000Effect of Infection on Breastfeeding Transmission of and on the Health of Infants Born to HIV-infected Mothers.

Tiffany Chang, Jeffrey Wiener, Sheila Dollard, Minal Amin, Sascha Ellington, Dumbani Kayira, Gerald Tegha, Denise Jamieson, Charles Van Der Horst, Athena Kourtis,

Open Forum Infect Dis (Open forum infectious diseases)
[2014, 1(Suppl 1):S292-S292]

Cited: 0 times

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Measurements of human herpesvirus 8 viral load in blood before and after leukoreduction filtration.

Sheila C Dollard, John D Roback, Clifford Gunthel, Minal M Amin, Sheilagh Barclay, Ericka Patrick, Matthew J Kuehnert,

<h4>Background</h4>Human herpesvirus 8 (HHV-8) is likely transmitted through blood transfusion in high-prevalence areas. The efficacy of leukoreduction filtration for reducing HHV-8 in blood has not been reported.<h4>Study design and methods</h4>Blood was drawn from 45 human immunodeficiency virus-positive men either with Kaposi's sarcoma (KS; n=21) or without KS (n=24) and subject ... Read more >>

Transfusion (Transfusion)
[2013, 53(10):2164-2167]

Cited: 2 times

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Efficient linking of birth certificate and newborn screening databases for laboratory investigation of congenital cytomegalovirus infection and preterm birth: Florida, 2008.

John M DePasquale, Karen Freeman, Minal M Amin, Sohyun Park, Samantha Rivers, Richard Hopkins, Michael J Cannon, Bonifacio Dy, Sheila C Dollard,

The objectives of this study are (1) to design an accurate method for linking newborn screening (NBS) and state birth certificate databases to create a de-identified study database; (2) To assess maternal cytomegalovirus (CMV) seroprevalence by measuring CMV IgG in newborn dried blood spots; (3) To assess congenital CMV infection ... Read more >>

Matern Child Health J (Maternal and child health journal)
[2012, 16(2):486-494]

Cited: 4 times

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National prevalence estimates for cytomegalovirus IgM and IgG avidity and association between high IgM antibody titer and low IgG avidity.

Sheila C Dollard, Stephanie A S Staras, Minal M Amin, D Scott Schmid, Michael J Cannon,

Primary cytomegalovirus (CMV) infection of the mother during pregnancy presents risk of CMV infection of the fetus with resulting permanent disability. CMV IgM antibody is generated following primary CMV infection but also can appear during nonprimary CMV infection and is thus of limited diagnostic use by itself. In contrast, the ... Read more >>

Clin Vaccine Immunol (Clinical and vaccine immunology : CVI)
[2011, 18(11):1895-1899]

Cited: 46 times

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Cytomegalovirus (CMV) shedding is highly correlated with markers of immunosuppression in CMV-seropositive women.

Ashley L Schoenfisch, Sheila C Dollard, Minal Amin, Lytt I Gardner, Robert S Klein, Kenneth Mayer, Anne Rompalo, Jack D Sobel, Michael J Cannon,

Cytomegalovirus (CMV) enters latency following primary infection and can subsequently reactivate. Reinfection with a different viral strain can also occur. During these events, CMV is shed in bodily fluids. This study examined correlates of CMV shedding in specimens obtained from the HIV Epidemiology Research Study, a multicenter cohort study of ... Read more >>

J Med Microbiol (Journal of medical microbiology)
[2011, 60(Pt 6):768-774]

Cited: 21 times

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Relationship between salivary shedding and seropositivity for Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) among South African children and adults: insights on why EBV infection is ubiquitous and KSHV is not.

Lisa Butler, Sheila Dollard, Minal Amin, Anisa Mosam, Jeffrey Martin,

Infect Agent Cancer (Infectious agents and cancer)
[2010, 5(Suppl 1):A69-A69]

Cited: 0 times

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Sex and geographic patterns of human herpesvirus 8 infection in a nationally representative population‐based sample in Uganda.

Benon Biryahwaho, Sheila C Dollard, Ruth M Pfeiffer, Fatma M Shebl, Stella Munuo, Minal M Amin, Wolfgang Hladik, Ruth Parsons, Sam M Mbulaiteye,

<h4>Background</h4>Human herpesvirus 8 (HHV8), the infectious cause of Kaposi sarcoma, varies dramatically across Africa, suggesting that cofactors correlated with large-area geographic or environmental characteristics may influence risk of infection. Variation in HHV8 seropositivity across small-area regions within countries in Africa is unknown. We investigated this issue in Uganda, where Kaposi ... Read more >>

J Infect Dis (The Journal of infectious diseases)
[2010, 202(9):1347-1353]

Cited: 25 times

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Use of screening dried blood spots for estimation of prevalence, risk factors, and birth outcomes of congenital cytomegalovirus infection.

Martin Kharrazi, Terri Hyde, Suzanne Young, Minal M Amin, Michael J Cannon, Sheila C Dollard,

<h4>Objectives</h4>To determine the birth prevalence of cytomegalovirus (CMV) in a population-based sample of newborns by use of dried blood spots compared with previous studies that used established detection methods, and to evaluate risk factors and birth outcomes for congenital CMV infection.<h4>Study design</h4>A total of 3972 newborn dried blood spots collected ... Read more >>

J Pediatr (The Journal of pediatrics)
[2010, 157(2):191-197]

Cited: 35 times

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