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Qingluoyin granules protect against adjuvant-induced arthritis in rats via downregulating the CXCL12/CXCR4-NF-κB signalling pathway.

Min Si, Zheng Ma, Jie Zhang, Xinwei Li, Rui Li, Chao Wang, Huiyu Jia, Shengyong Luo,

<h4>Context</h4>Qingluoyin (QLY) is a traditional Chinese medicine (TCM) formula which has been used in treating human rheumatoid arthritis (RA) for years in China.<h4>Objective</h4>This study investigates the effect of QLY granules on adjuvant arthritis (AA) and the possible mechanism.<h4>Materials and methods</h4>Sprague-Dawley (SD) rats were injected with Complete Freund's adjuvant (CFA) to ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):1441-1451]

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Deep Learning-Based Quantification of Visceral Fat Volumes Predicts Posttransplant Diabetes Mellitus in Kidney Transplant Recipients.

Ji Eun Kim, Sang Joon Park, Yong Chul Kim, Sang-Il Min, Jongwon Ha, Yon Su Kim, Soon Ho Yoon, Seung Seok Han,

<b>Background:</b> Because obesity is associated with the risk of posttransplant diabetes mellitus (PTDM), the precise estimation of visceral fat mass before transplantation may be helpful. Herein, we addressed whether a deep-learning based volumetric fat quantification on pretransplant computed tomographic images predicted the risk of PTDM more precisely than body mass ... Read more >>

Front Med (Lausanne) (Frontiers in medicine)
[2021, 8:632097]

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Presence of a survival benefit of HLA-incompatible living donor kidney transplantation compared to waiting or HLA-compatible deceased donor kidney transplantation with a long waiting time.

Tai Yeon Koo, Ju Han Lee, Sang-Il Min, Yonggu Lee, Myung Soo Kim, Jongwon Ha, Soon Il Kim, Curie Ahn, Yu Seun Kim, Jayoun Kim, Kyu Ha Huh, Jaeseok Yang,

HLA-incompatible living donor kidney transplantation (LDKT) is one of efforts to increase kidney transplantation opportunity for sensitized patients with kidney failure. However, there are conflicting reports for outcomes of HLA-incompatible kidney transplantation compared to patients who wait for HLA-compatible deceased donor kidney transplantation (DDKT) in the United States and United ... Read more >>

Kidney Int (Kidney international)
[2021, 100(1):206-214]

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Serum Kisspeptin and AMH Levels Are Good References for Precocious Puberty Progression.

Jiang Xue, Wei Song, Min Si, Chao Sun, Kailin Li, Wei Wang, Shuang Liang, Yanfeng Xiao,

<h4>Aim</h4>The aim of this study was to evaluate the levels of kisspeptin and AMH in children with PT or CPP or controls to provide a reference for diagnosis and prognosis.<h4>Methods</h4>38 Chinese children with central precocious puberty (CPP), 38 Chinese children with premature thelarche (PT), and 75 controls were recruited.<h4>Results</h4>In CPP ... Read more >>

Int J Endocrinol (International journal of endocrinology)
[2020, 2020:3126309]

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Risk of Graft Failure in Kidney Recipients with Cured Post-Transplant Cancer.

Ji Eun Kim, Sang Il Min, Hajeong Lee, Jongwon Ha, Yon Su Kim, Seung Seok Han,

BACKGROUND:Post-transplant cancer (PTC) is a critical complication after kidney transplantation. However, whether successfully cured PTC affects the long-term graft outcome remains unclear. METHODS:We retrospectively reviewed 1,629 kidney transplant recipients from 1995 to 2017 after excluding patients with post-transplant hematologic or advanced non-curable cancers and who underwent allograft nephrectomy because of ... Read more >>

J Korean Med Sci (Journal of Korean medical science)
[2020, 35(20):e166]

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Klotho as a potential predictor of deceased donor kidney transplantation outcomes.

Suh Min Kim, Ahram Han, Sanghyun Ahn, Sang-Il Min, Seung-Kee Min, Jongwon Ha,

<h4>Purpose</h4>Klotho is an antiaging factor mainly produced by renal tubular cells. Klotho is reportedly decreased in an animal model of acute kidney injury and patients with chronic kidney disease. However, information on Klotho expression after kidney transplantation is limited. We analyzed the correlation between donor Klotho expression and clinical outcomes ... Read more >>

Ann Surg Treat Res (Annals of surgical treatment and research)
[2020, 98(6):332-339]

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Weaning Immunosuppressant in Patients with Failing Kidney Grafts and The Outcomes: A Single-Center Retrospective Cohort Study.

Hyunjin Ryu, Yong Chul Kim, Jong Joo Moon, Eun Young Song, Sang-Il Min, Jongwon Ha, Kwon Wook Joo, Yon Su Kim, Curie Ahn, Hajeong Lee,

An immunosuppressant weaning protocol in failing allografts has not yet been established. Maintaining immunosuppressants would preserve residual renal function (RRF) and prevent graft intolerance syndrome and sensitization but would increase the risks of infection and malignancy. In this study, graft failure cases after kidney transplantation in a single center were ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):6425]

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Mechanism of Ca2+-mediated NOX modulated in ROS metabolism induced by T-2 toxin in potato tuber.

Zhang Rui, Xue Huali, Si Min, Bi Yang, Nan Mina, Zong Yuanyuan, Long Haitao, Dov Prusky, Cheng Xiaoyan,

T-2 toxin at low concentrations can induce ROS accumulation and modulate host resistance in plants. NOX plays crucial roles in ROS production and is regulated by Ca2+via direct binding to EF-hand motifs. In this study, the effect of EGTA (Ca2+ chelating agent) on the expression and enzymatic activity of NOX, ... Read more >>

Food Chem (Food chemistry)
[2020, 317:126416]

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Metformin Delays the Development of Atherosclerosis in Type 1 Diabetes Mellitus via the Methylglyoxal Pathway.

Aihong Liu, Kailin Li, Linlin Xu, Min Si, Guoxin Teng, Guimei Li, Jiang Xue, Shuang Liang, Wei Song,

INTRODUCTION:The aim of our study was to determine the effect of metformin administration on juvenile type 1 diabetes mellitus and atherosclerosis in apolipoprotein E null (ApoE-/-) mice and to explore the mechanism involved. METHODS:Eighteen male ApoE-/- mice were injected with streptozotocin to induce diabetes (diabetic group) and 18 mice who ... Read more >>

Diabetes Ther (Diabetes therapy : research, treatment and education of diabetes and related disorders)
[2020, 11(3):633-642]

Cited: 2 times

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Erratum: Post-Transplant Lymphoproliferative Diseases in Pediatric Kidney Allograft Recipients with Epstein-Barr Virus Viremia.

Hyesun Hyun, Eujin Park, Myunghyun Cho, Sang Il Min, Jongwon Ha, Hyoung Jin Kang, Hee Young Shin, Il Soo Ha, Hae Il Cheong, Yo Han Ahn, Hee Gyung Kang,

This corrects the article on e203 in vol. 34, PMID: 31373185. ... Read more >>

J Korean Med Sci (Journal of Korean medical science)
[2020, 35:e29]

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Fetal outcomes after intentional ingestion of paraquat: A case report.

Jianshi Chen, Xiangdong Jian, Guangcai Yu, Min Si, Baotian Kan,

<h4>Rationale</h4>Despite the fact that treatment of paraquat poisoning in pregnant women and their fetuses is challenging and raises ethical issues, it is rarely reported in the literature. We report the case of a pregnant woman who took paraquat intentionally.<h4>Patient concerns</h4>A 36-year-old woman at 38 weeks gestational age, in an apparent ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(1):e18136]

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Nationwide Epidemiologic Study of Abdominal Aortic Aneurysms in Korea: A Cross-Sectional Study Using National Health Insurance Review and Assessment Service Data.

Chanjoong Choi, Sanghyun Ahn, Sang-Il Min, Moonsang Ahn, Jongwon Ha, Hyung-Jin Yoon, Rina So, Sung Hyouk Choi, Seung-Kee Min,

Purpose:The prevalence and treatment patterns of abdominal aortic aneurysm (AAA) vary according to ethnicity and region. This study analyzed nationwide data on the epidemiology, practice patterns, and mortality rates of AAA in Korea. Materials and Methods:Data from patients treated for AAA from 2012 to 2016 were extracted from the Korean ... Read more >>

Vasc Specialist Int (Vascular specialist international)
[2019, 35(4):193-201]

Cited: 2 times

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Noncoding RNA miR-205-5p mediates osteoporosis pathogenesis and osteoblast differentiation by regulating RUNX2.

Mingwei Huang, Xiaowen Li, Can Zhou, Min Si, Haiyan Zheng, Lianhua Chen, Hongcheng Ding,

As a kind of noncoding RNAs, microRNAs (miRNAs) play important roles in disease pathogenesis by regulating gene expression. However, the molecular mechanism of miRNAs in osteoporosis remains largely unknown. In the present study, we aim to explore the genome-wide miRNAs expression profile and the regulatory mechanism of miR-205-5p in osteoporosis. ... Read more >>

J Cell Biochem (Journal of cellular biochemistry)
[2020, 121(10):4196-4203]

Cited: 1 time

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Author Correction: Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients.

Minji Sohn, Myeong Gyu Kim, Nayoung Han, In-Wha Kim, Jungsoo Gim, Sang-Il Min, Eun Young Song, Yon Su Kim, Hun Soon Jung, Young Kee Shin, Jongwon Ha, Jung Mi Oh,

An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):2486]

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Long-term Mortality Risks Among Living Kidney Donors in Korea.

Yaerim Kim, Mi-Yeon Yu, Kyung Don Yoo, Chang Wook Jeong, Hyeon Hoe Kim, Sang-Il Min, Jongwon Ha, Yunhee Choi, Ah Ryoung Ko, Jae Moon Yun, Sang Min Park, Seung Hee Yang, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Curie Ahn, Yon Su Kim, Hajeong Lee,

<h4>Rationale & objective</h4>Living kidney donors may have a higher risk for death and kidney failure. This study aimed to investigate the long-term mortality experience of living kidney donors compared with members of the general public in Korea who underwent voluntary health examinations.<h4>Study design</h4>Cohort study.<h4>Setting & participants</h4>We first calculated standardized mortality ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2020, 75(6):919-925]

Cited: 2 times

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Mobile medication manager application to improve adherence with immunosuppressive therapy in renal transplant recipients: A randomized controlled trial.

Ahram Han, Sang-Il Min, Sanghyun Ahn, Seung-Kee Min, Hye-Jin Hong, Nayoung Han, Yon Su Kim, Curie Ahn, Jongwon Ha,

BACKGROUND:Nonadherence to immunosuppressive therapy after renal transplantation is associated with poor graft outcomes. We aimed to evaluate whether the use of the Adhere4U mobile medication manager application could improve adherence among renal transplant recipients ≥1 year posttransplantation. Adhere4U can provide medication reminders, monitor medication use, and provide information on immunosuppressants. ... Read more >>

PLoS One (PloS one)
[2019, 14(11):e0224595]

Cited: 5 times

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Post-Transplant Lymphoproliferative Diseases in Pediatric Kidney Allograft Recipients with Epstein-Barr Virus Viremia.

Hyesun Hyun, Eujin Park, Myunghyun Cho, Sang Il Min, Jongwon Ha, Hyoung Jin Kang, Hee Young Shin, Il Soo Ha, Hae Il Cheong, Yo Han Ahn, Hee Gyung Kang,

<h4>Background</h4>Post-transplant lymphoproliferative disease (PTLD) is one of the major complications of organ transplantation, especially in children with Epstein-Barr virus (EBV) viremia (EV). We performed a retrospective study to evaluate risk factors for PTLD in children with EV.<h4>Methods</h4>Among 199 pediatric kidney transplantation (KT) recipients at our center from January 2001 to ... Read more >>

J Korean Med Sci (Journal of Korean medical science)
[2019, 34(30):e203]

Cited: 1 time

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Possible beneficial association between renin-angiotensin-aldosterone-system blockade usage and graft prognosis in allograft IgA nephropathy: a retrospective cohort study.

Sehoon Park, Chung Hee Baek, Heounjeong Go, Young Hoon Kim, Sang-Il Min, Jongwon Ha, Yong Chul Kim, Jung Pyo Lee, Yon Su Kim, Kyung Chul Moon, Su-Kil Park, Hajeong Lee,

<h4>Background</h4>Although immunoglobulin A nephropathy (IgAN) is associated with an increased risk of renal allograft failure, evidences for its treatment, including renin-angiotensin-aldosterone system blockade (RAASB) usage, remain limited.<h4>Methods</h4>In this bi-center retrospective cohort study, we included patients who were recently diagnosed with IgAN through allograft biopsies. We identified their 6-month antihypertensive medication ... Read more >>

BMC Nephrol (BMC nephrology)
[2019, 20(1):354]

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2,4‐D‐induced parthenocarpy in pear is mediated by enhancement of GA4 biosynthesis

Liu Cong, Rongrong Yue, Huibin Wang, Jianlong Liu, Rui Zhai, Jie Yang, Meng Wu, Min Si, Haiqi Zhang, Chengquan Yang, Lingfei Xu, Zhigang Wang,

Parthenocarpy, the productions of seedless fruit without pollination or fertilization, is a potentially desirable trait in many commercially grown fruits, especially in pear, which is self‐incompatible. Phytohormones play important roles in fruit set, a process crucial for parthenocarpy. In this study, 2,4‐dichlorophenoxyacetic acid (2,4‐D), an artificially synthesized plant growth regulator ... Read more >>

Physiol Plant (Physiologia plantarum)
[2019, 166(3):812-820]

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The Use of Antithrombotics Is Not Beneficial for Conservative Management of Spontaneous Isolated Dissection of the Superior Mesenteric Artery: A Meta-analysis.

Sanghyun Ahn, Hyejin Mo, Ahram Han, Sang-Il Min, Seung-Kee Min, Jongwon Ha, Chang-Hyun Lee, Myoung-Jin Jang, In Mok Jung,

<h4>Background</h4>Conservative treatment is feasible in most patients with spontaneous isolated dissection of the superior mesenteric artery (SID-SMA). However, the role of antiplatelet agents and anticoagulants is not well defined in either symptomatic or asymptomatic SID-SMA. This study aimed to conduct a meta-analysis, including a single-arm study, comparing the resolution rate ... Read more >>

Ann Vasc Surg (Annals of vascular surgery)
[2019, 60:415-423.e4]

Cited: 4 times

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Baseline characteristics of arm vessels by preoperative duplex ultrasonography in Korean patients for hemodialysis vascular access.

Minji Cho, Jung Sun Kim, Sungsin Cho, Won Pyo Cho, Chanjoong Choi, Sanghyun Ahn, Sang-Il Min, Jongwon Ha, Seung-Kee Min,

BACKGROUND:Preoperative mapping with duplex ultrasonography is crucial for successful vascular access creation for hemodialysis. The aims of this study are to assess the baseline characteristics of arm vessels by preoperative duplex ultrasonography in Korean patients, to find out a preoperative duplex ultrasonography parameter precluding distal arteriovenous fistula creation, to assess ... Read more >>

J Vasc Access (The journal of vascular access)
[2019, 20(6):646-651]

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Clinical importance of the updated Oxford classification in allograft IgA nephropathy.

Sehoon Park, Heounjeong Go, Chung Hee Baek, Young Hoon Kim, Yong Chul Kim, Seung Hee Yang, Jung Pyo Lee, Sang-Il Min, Jongwon Ha, Eun Young Song, Yon Su Kim, Su-Kil Park, Hajeong Lee, Kyung Chul Moon,

With the recent update to the Oxford classification for allograft IgA nephropathy (IgAN), additional investigations on the clinical significance of the updated components are warranted. We performed a retrospective cohort study at two tertiary hospitals. Kidney transplant recipients diagnosed with allograft IgAN were included in the study after additional review ... Read more >>

Am J Transplant (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons)
[2019, 19(10):2855-2864]

Cited: 3 times

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Timing of referral for vascular access for hemodialysis: Analysis of the current status and the barriers to timely referral.

Suh Min Kim, Ahram Han, Sanghyun Ahn, Sang-Il Min, Jongwon Ha, Kwon-Wook Joo, Seung-Kee Min,

<h4>Introduction</h4>Current guidelines recommend the placement of vascular access 6 months before the anticipated start of hemodialysis therapy; however, many patients start hemodialysis using a central venous catheter. We investigated the timing of referral for vascular access, the vascular access type at hemodialysis initiation, and the barriers to a timely referral.<h4>Methods</h4>The study ... Read more >>

J Vasc Access (The journal of vascular access)
[2019, 20(6):659-665]

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Physical Illnesses and Medically Serious Suicide Attempts in Rural China.

Shenghua Jin, Yanzheng Liu, Dwight A Hennessy, Long Sun, Yuli Zang, Min Si, Jie Zhang,

Background: Physical illness is a strong correlate of suicidal behavior. However, its impact on attempted suicide in rural China is under-studied. Aims: This study was designed to assess the influence of physical illness on risk of suicide attempts and to identify distinguishing characteristics among medically serious suicide attempters with physical ... Read more >>

Crisis (Crisis)
[2020, 41(1):15-23]

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Development of a novel linear model for predicting recipient's post-transplant serum creatinine level after living donor kidney transplantation: A multicenter cross-validation study.

Jinsoo Rhu, Sung Joo Kim, Kyo Won Lee, Jae Berm Park, Kyunga Kim, Heejin Yoo, Hyejin Mo, Chanjoong Choi, Sang-Il Min, Jongwon Ha,

<h4>Background</h4>This study was designed to develop and cross-validate a statistical model for predicting post-transplant serum creatinine of living donor kidney transplantation.<h4>Materials and methods</h4>Adult recipients of living donor kidney transplantation from August 2012 to October 2017 at Samsung Medical Center (SMC) and Seoul National University Hospital (SNUH) with normal post-transplant protocol ... Read more >>

PLoS One (PloS one)
[2019, 14(4):e0214247]

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