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Author Min Liu

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Molecular-dynamics simulations on the mesophase transition induced by oscillatory shear in imidazolium-based ionic liquid crystals.

Min Liu, Hayato Shiba, Huashan Liu, Hailong Peng,

Molecular dynamics simulations were performed on a 1-dodecyl-3-methylimidazolium hexafluorophosphate ([C<sub>12</sub>mim][PF<sub>6</sub>]) ionic liquid crystal (ILC) with the application of an oscillatory shear. We found that the oscillatory shear can both accelerate and suppress mesophase formation depending on shear amplitude. A small amplitude shear can speed up the mesophase transition dynamics and ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2021, 23(11):6496-6508]

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Construction and theoretical insights into the ESIPT fluorescent probe for imaging formaldehyde in vitro and in vivo.

Anyao Bi, Min Liu, Shuai Huang, Fan Zheng, Jipeng Ding, Junyong Wu, Gao Tang, Wenbin Zeng,

We report the first ESIPT-based probe ABTB, for the highly sensitive and selective imaging of formaldehyde (FA). The various theoretical calculations have been systematically performed, and clearly unravel the lighting mechanism of the fluorescent probe for FA. Additionally, the probe was successfully applied in monitoring endogenous FA in the brain ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(28):3496-3499]

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Self-assembly of hyaluronic acid-mediated tumor-targeting theranostic nanoparticles.

Xiaoxuan Zhou, Chengbin He, Min Liu, Qingqing Chen, Lingjie Zhang, Xiaodan Xu, Hongxia Xu, Yue Qian, Feidan Yu, Yan Wu, Yuxin Han, Bing Xiao, Jianbin Tang, Hongjie Hu,

Theranostic nanoparticles (NPs) have emerged as promising candidates for cancer diagnosis and treatment. Manganese dioxide (MnO<sub>2</sub>)-based NPs are potential contrast agents with excellent paramagnetic property and biocompatibility, exhibiting satisfactory magnetic resonance imaging (MRI) effects and biological safety. Recently, hyaluronic acid (HA) has gained increasing interest due to its tumor-targeting ability, ... Read more >>

Biomater Sci (Biomaterials science)
[2021, 9(6):2221-2229]

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B-Doped core-shell [email protected] nanozymes: active site identification and bacterial inhibition.

Xingxing Jiang, Kang Liu, Qiang Li, Min Liu, Minghui Yang, Xiang Chen,

The rational design of nanozymes as new "antibiotics" for bacterial therapy is a promising area in healthcare. Herein, B-doped core-shell [email protected] nanozymes functioned with peroxidase-like activity for bacterial inhibition were studied. Experimental and theoretical results show that the BCO<sub>2</sub> site enables a much lower energy barrier than the BC<sub>2</sub>O site, ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, 57(13):1623-1626]

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Luminescent net-like inorganic scaffolds with europium-doped hydroxyapatite for enhanced bone reconstruction.

Min Liu, Mengmeng Shu, Jiaqing Yan, Xuxu Liu, Ruifeng Wang, Zhiyao Hou, Jun Lin,

Bone reconstruction is an urgent problem during clinical treatment. In the past few decades, the construction of composite scaffolds has been a hot spot in the research field of bone tissue engineering (BTE). However, the disadvantages of composite materials raise our awareness to explore the potential application of hydroxyapatite (HAp) ... Read more >>

Nanoscale (Nanoscale)
[2021, 13(2):1181-1194]

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Design, synthesis and biological evaluation of dihydro-2-quinolone platinum(iv) hybrids as antitumor agents displaying mitochondria injury and DNA damage mechanism.

Zhifang Liu, Zuojie Li, Tao Du, Yan Chen, Qingpeng Wang, Guoshuai Li, Min Liu, Ning Zhang, Dacheng Li, Jun Han,

The design of novel platinum(iv) complexes with mitochondria injury competence, besides the DNA damage mechanism, is a promising way to develop new platinum drugs. Herein, dihydro-2-quinolone (DHQLO) as a mitocan was incorporated into the platinum(iv) system for the first time to prepare a new series of DHQLO platinum(iv) compounds. Complex ... Read more >>

Dalton Trans (Dalton transactions (Cambridge, England : 2003))
[2021, 50(1):362-375]

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Enantioselective dearomative [3+2] annulation of 5-amino-isoxazoles with quinone monoimines.

Hui Liu, Yingkun Yan, Jiayan Zhang, Min Liu, Shaobing Cheng, Zhouyu Wang, Xiaomei Zhang,

The first enantioselective dearomative [3+2] annulation of 5-amino-isoxazoles with quinone monoimines was realized using a chiral phosphoric acid as catalyst. Various novel (bridged) isoxazoline fused dihydrobenzofurans bearing two continuous quaternary stereocenters were achieved in moderate to good yields (up to 94%) with moderate to good enantioselectivities (up to 98% ee). ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2020, 56(88):13591-13594]

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A zwitterionic hydrogel coated titanium surface with high-efficiency endothelial cell selectivity for rapid re-endothelialization.

Chiyu Wen, Jiamin Zhang, Yongjian Li, Weiwei Zheng, Min Liu, Yingnan Zhu, Xiaojie Sui, Xiangyu Zhang, Qiang Han, Yu Lin, Jing Yang, Lei Zhang,

Coronary stent implantation is an effective procedure for percutaneous coronary intervention treatment. However, its long-term safety and efficacy are still hindered by the in-stent restenosis and late thrombus formation. Herein, an anti-biofouling and endothelial cell selective zwitterionic hydrogel coating was developed to simultaneously enhance the nonspecific resistance and rapid re-endothelialization ... Read more >>

Biomater Sci (Biomaterials science)
[2020, 8(19):5441-5451]

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The palladium-catalyzed direct C3-cyanation of indoles using acetonitrile as the cyanide source.

Bifu Liu, Min Liu, Qiang Li, Yuanhua Li, Kejun Feng, Yongbo Zhou,

The ligand-free palladium-catalyzed C3-cyanation of indoles via direct C-H functionalization was achieved. This protocol, utilizing CH<sub>3</sub>CN as a green and readily available cyanide source, produced the desired products in moderate to good yields through transition-metal-catalyzed C-CN bond cleavage. ... Read more >>

Org Biomol Chem (Organic & biomolecular chemistry)
[2020, 18(31):6108-6114]

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CLEC14A protects against podocyte injury in mice with adriamycin nephropathy.

Zeyu Su, Yujia Li, Hang Lv, Xiaoyang Cui, Min Liu, Ziying Wang, Yan Zhang, Junhui Zhen, Wei Tang, Xiaojie Wang, Fan Yi,

Podocyte injury is a major determinant of focal segmental glomerular sclerosis (FSGS) and the identification of potential therapeutic targets for preventing podocyte injury has clinical importance for the treatment of FSGS. CLEC14A is a single-pass transmembrane glycoprotein belonging to the vascular expressed C-type lectin family. CLEC14A is found to be ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(7):e21711]

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Trefoil Factors as Screening Biomarkers for Gastric Cancer and Premalignant Lesions: A Cross-Sectional Population-Based Cohort Study

Xiangyi Zan, Zhaofeng Chen, Qinghong Guo, Yuping Wang, Zhiyi Zhang, Rui Ji, Ya Zheng, Jinhua Zhang, Zhengqi Wu, Min Li, Xiang Wang, Yuwei Ye, Xiaohua Li, Feng An, Chuanggui Xu, Linzhi Lu, Ping Fan, Jun Zhang, Quanlin Guan, Qiang Li, Min Liu, Qian Ren, Xiaobin Hu, Hong Lu, Yuling Wang, Hongling Zhang, Yue Zhao, Xi Gou, Xiaochuang Shu, Jun Wang, Zenan Hu, Rong Liu, Hao Yuan, Jiankang Liu, Liang Qiao, Yongning Zhou,

<h4>Background: </h4> The lack of effective biomarkers for screening gastric cancer (GC) and premalignant lesions (PMLs) is a significant roadblock in the prevention and early intervention of GC. We aimed to identify noninvasive biomarkers to improve the screening of high-risk populations. <h4>Methods:</h4> We evaluated 25,000 adults residing in Wuwei. We ... Read more >>

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Phosphorylation of TRIP13 at Y56 induces Radiation Resistance but Sensitizes Head and Neck Cancer to Cetuximab.

Rajat Banerjee, Min Liu, Emily Bellile, Ligia B Schmitd, Mitsuo Goto, Marsha-Kay Hutchinson, Priyanka Singh, Shuang Zhang, Dilna P V Damodaran, Mukesh K Nyati, Matthew E Spector, Brent Ward, Gregory Wolf, Keith Casper, Michelle Mierzwa, Nisha J D'Silva,

Radiation therapy, a mainstay of treatment for head and neck cancer, is not always curative due to the development of treatment resistance; additionally, multi-institutional trials have questioned the efficacy of concurrent radiation with cetuximab, the EGFR inhibitor. We unraveled a mechanism for radiation resistance; radiation induces EGFR, which phosphorylates TRIP13 ... Read more >>

Mol Ther (Molecular therapy : the journal of the American Society of Gene Therapy)
[2021, :]

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A phase I study of the safety and activity of K-001 in patients with advanced pancreatic ductal adenocarcinoma.

Jiujie Cui, Haiyan Yang, Jue Liu, Donghui Chen, Jiong Hu, Haiyan Zhang, Yu Wang, Ting Han, Tiebo Mao, Feng Jiao, Ewelina Biskup, Yaotian Pan, Min Liu, Liwei Wang,

<h4>Background</h4>Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease that lack of effective therapeutic drugs. K-001 is an oral antitumor drug made from active ingredients of marine microorganisms. The current study aimed to evaluate safety and antitumor activity of K-001 in patients with advanced PDAC.<h4>Methods</h4>In this phase I, open-label trial, patients ... Read more >>

BMC Cancer (BMC cancer)
[2021, 21(1):672]

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Dual Inorganic Sacrificial Template Synthesis of Hierarchically Porous Carbon with Specific N Sites for Efficient Oxygen Reduction.

Jiayu Hao, Yanqiu Wang, Xiaoqing Qiu, Min Liu, Wenzhang Li, Jie Li,

It is still a challenge to achieve efficiently controlled preparation of functional oxygen reduction reaction (ORR) carbon electrocatalysts with multi-preferred structures (hierarchically porous networks and specific carbon-nitrogen bonds) from carbohydrate-containing small molecules via simple one-step pyrolysis. Based on the step-by-step spontaneous gas-foaming strategy, we successfully prepare 3D hierarchically porous networks ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2021, :]

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Genomic insights into molecular adaptation to intertidal environments in the mangrove Aegiceras corniculatum.

Xiao Feng, Guohong Li, Shaohua Xu, Weihong Wu, Qipian Chen, Shao Shao, Min Liu, Nan Wang, Cairong Zhong, Ziwen He, Suhua Shi,

Mangroves have colonized extreme intertidal environments characterized by high salinity, hypoxia, and other abiotic stresses. Aegiceras corniculatum, a pioneer mangrove species that evolved two specialized adaptive traits (salt secretion and crypto-vivipary), is an attractive ecological model to investigate molecular mechanisms underlying adaptation to intertidal environments. We de novo assembled a ... Read more >>

New Phytol (The New phytologist)
[2021, :]

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A novel nomogram for predicting locoregional recurrence risk in breast cancer patients treated with neoadjuvant chemotherapy and mastectomy.

Zhou Huang, Mei Shi, Wei-Hu Wang, Liang-Fang Shen, Yu Tang, Qing-Lin Rong, Li Zhu, Xiao-Bo Huang, Jian Tie, Jia-Yi Chen, Jun Zhang, Hong-Fen Wu, Jing Cheng, Min Liu, Chang-Ying Ma, Shu-Lian Wang, Ye-Xiong Li,

<h4>Background</h4>This study aimed to establish a nomogram for predicting locoregional recurrence (LRR) in breast cancer patients treated with neoadjuvant chemotherapy (NAC) and mastectomy.<h4>Methods</h4>A total of 2368 patients who received NAC and mastectomy between 2000 and 2014 from 12 grade A tertiary hospitals in China were analyzed retrospectively. The nomogram was ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2021, :]

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Palladium-Catalyzed Decarbonylative Catellani Reaction

Huixiong Dai, Ming-Liang Han, Jun-Jie Chen, Hui Xu, Wei Huang, Yue-Wen Liu, Xing Wang, Min Liu, Zi-Qiong Guo, Zhi-Cong Huang,

<p><b>The transition metal-catalyzed Catellani reaction of aryl halides has drawn significant attentions as an efficient and practical tool for the synthesis of substituted arenes. We describe herein the palladium-catalyzed, norbornene (NBE)-mediated synthesis of polysubstituted arenes from aromatic acids via decarbonylative Catellani reaction. A variety of alkenyl, alkyl, aryl and sulfur ... Read more >>

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Enhanced Recovery After Surgery Impact on the Systemic Inflammatory Response of Patients Following Gynecological Oncology Surgery: A Prospective Randomized Study.

Jin Peng, Ruiying Dong, Jianfen Jiao, Min Liu, Xi Zhang, Hualei Bu, Ping Dong, Shasha Zhao, Naidong Xing, Shuai Feng, Xingsheng Yang, Beihua Kong,

<h4>Objective</h4>Enhanced recovery after surgery (ERAS) protocol has widely gained acceptance in gynecological surgery. Its safety and efficacy should be evaluated fully via well-designed, randomized, control trials. The main objective of our study is to compare the ERAS protocol with the conventional perioperative care program after gynecological oncology. Furthermore, the secondary ... Read more >>

Cancer Manag Res (Cancer management and research)
[2021, 13:4383-4392]

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Plasmon-enhanced nonlinear nanofocusing of gold nanoprisms driven via an ultrafast azimuthal vector beam.

Wending Zhang, Lu Zhang, Fanfan Lu, Donghui Bai, Tianyang Xue, Chao Meng, Min Liu, Dong Mao, Feng Gao, Ting Mei,

We present the plasmon-enhanced nonlinear nanofocusing of a gold (Au) nanoprism array substrate (ANAS) driven via an ultrafast azimuthal vector beam (AVB). Theoretical calculations show that the electric-field intensity of the ANAS vertically excited via the femtosecond AVB is higher than that of LPB excitation. In this experiment, the second-order ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(13):7045-7050]

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Squamous cell carcinoma subverts adjacent histologically normal epithelium to promote lateral invasion.

Priyanka Singh, Rajat Banerjee, Songlin Piao, Marcell Costa de Medeiros, Emily Bellile, Min Liu, Dilna Damodaran Puthiya Veettil, Ligia B Schmitd, Nickole Russo, Erika Danella, Ronald C Inglehart, Kyriel M Pineault, Deneen M Wellik, Greg Wolf, Nisha J D'Silva,

Recurrent and new tumors, attributed in part to lateral invasion, are frequent in squamous cell carcinomas and lead to poor survival. We identified a mechanism by which cancer subverts adjacent histologically normal epithelium to enable small clusters of cancer cells to burrow undetected under adjacent histologically normal epithelium. We show ... Read more >>

J Exp Med (The Journal of experimental medicine)
[2021, 218(6):]

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Loss of Setd2 associates with aberrant microRNA expression and contributes to inflammatory bowel disease progression in mice.

Yucan Chen, Min Liu, Weidi Wang, Wenxiang Cai, WeiChen Song, Li Li, Guan Ning Lin,

Both SETD2-mediated H3K36me3 and miRNAs play critical epigenetic roles in inflammatory bowel disease (IBD) and involve in the dysfunctional intestinal barrier. However, little is known about cross-talk between these two types of regulators in IBD progression. We performed small RNA sequencing of Setd2 epithelium-specific knockout mice (Setd2<sup>Vil-KO</sup>) and wild-type controls, ... Read more >>

Genomics (Genomics)
[2021, 113(4):2441-2454]

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LuxQ-LuxU-LuxO pathway regulates biofilm formation by Vibrio parahaemolyticus.

Min Liu, Xinyuan Zhu, Ce Zhang, Zhe Zhao,

Vibrio parahaemolyticus, a common foodborne pathogen, can form biofilms for survival in various environments and for bacterial transmission. Lux systems in Vibrio species are the typical two-component signal transduction systems, which have been demonstrated to contribute to various phenotypes; however, the functions of each homolog of the Lux system in ... Read more >>

Microbiol Res (Microbiological research)
[2021, 250:126791]

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Efficient three-phase electrocatalytic CO2 reduction to formate on superhydrophobic Bi-C interfaces.

Yifan Jiang, Xiaodong Zhang, Dafu Xu, Wenzhang Li, Min Liu, Xiaoqing Qiu,

Bi-C catalysts with the three-phase interfaces of CO2 (gas), electrolyte (liquid) and catalyst (solid) exhibit a remarkable electrocatalytic CO2 reduction (ECR) to formate selectivity (above 95% faradaic efficiency) with a high current (100 mA cm-2) in a broad potential range. ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2021, :]

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Investigation on Crystallization and Magnetic Properties of (Nd, Pr, Ce)2Fe14B/α-Fe Nanocomposite Magnets by Microwave Annealing Treatment.

Zhanyong Wang, Changping Shangguan, Zemin Wang, Tianpeng Wang, Lianbo Wang, Min Liu, Yanli Sui,

In the present work, the structures and magnetic properties of (Nd, Pr, Ce) <sub>2</sub>Fe<sub>14</sub>B/α-Fe nanocomposite magnets were thoroughly investigated. The microwave annealing was applied to achieve a uniform heating effect and uniform grains. Microwave annealing is more favorable to obtain α-Fe phase than conventional annealing, which leads to the enhanced ... Read more >>

Materials (Basel) (Materials (Basel, Switzerland))
[2021, 14(11):]

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Integrated Analyses Reveal the Multi-Omics and Prognostic Characteristics of ATP5B in Breast Cancer.

Min Liu, Yuxuan Xu, Yaoyao Zhou, Ronggang Lang, Zhenyu Shi, Jing Zhao, Yuanyuan Meng, Li Bao,

The beta subunit of F1Fo-ATP synthase (ATP5B) has been demonstrated to play an essential role in tumor progression and metastasis. However, there has been no comprehensive pan-cancer multi-omics analysis of ATP5B, while the clinical relevance of ATP5B and its potential mechanism in regulating breast cancer are still poorly understood. In ... Read more >>

Front Genet (Frontiers in genetics)
[2021, 12:652474]

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