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Author Michi M Shinohara

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Treatment of pyoderma gangrenosum: A multicenter survey-based study assessing satisfaction and quality of life.

Misty M Hobbs, Rebecca Byler, Emile Latour, Lauren Bonomo, Kerry Hennessy, Carla N Cruz-Diaz, Michi M Shinohara, Lucia Seminario-Vidal, Kanade Shinkai, Alex G Ortega-Loayza,

Pyoderma gangrenosum (PG) lacks consensus regarding treatment, and no prior studies assess treatment satisfaction in PG. The objective of this study was to determine patient-reported satisfaction in the treatment of PG, and associations with satisfaction. Methodology was a multicenter cross-sectional survey for patients who received systemic medication(s) to treat PG. ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2021, :e14736]

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Impact of clinical photographs on the accuracy and confidence in the histopathological diagnosis of mycosis fungoides.

Rouba Hadi, Timothy I Miller, Caitlin May, Julia S Lehman, Daniel D Bennett, Melissa Piliang, Oliver Chang, Michi M Shinohara,

<h4>Background</h4>The histopathological diagnosis of MF is challenging, and there is significant overlap with benign inflammatory processes. Clinical features may be relevant in the assessment of skin biopsies.<h4>Methods</h4>We provided photomicrographs to board-certified dermatopathologists and one hematopathologist with and without accompanying clinical photographs and assessed accuracy and confidence in diagnosing MF.<h4>Results</h4>We found ... Read more >>

J Cutan Pathol (Journal of cutaneous pathology)
[2020, :]

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Behçet disease (BD) and BD-like clinical phenotypes: NF-κB pathway in mucosal ulcerating diseases.

Sandro F Perazzio, Eric J Allenspach, Kari K Eklund, Markku Varjosalo, Michi M Shinohara, Troy R Torgerson, Mikko R J Seppänen,

Behçet's disease (BD) is a heterogeneous multi-organ disorder in search of a unified pathophysiological theory and classification. The disease frequently has overlapping features resembling other disease clusters, such as vasculitides, spondyloarthritides and thrombophilias with similar genetic risk variants, namely HLA-B*51, ERAP1, IL-10, IL-23R. Many of the BD manifestations, such as ... Read more >>

Scand J Immunol (Scandinavian journal of immunology)
[2020, 92(5):e12973]

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Neoadjuvant Nivolumab for Patients With Resectable Merkel Cell Carcinoma in the CheckMate 358 Trial.

Suzanne L Topalian, Shailender Bhatia, Asim Amin, Ragini R Kudchadkar, William H Sharfman, Celeste Lebbé, Jean-Pierre Delord, Lara A Dunn, Michi M Shinohara, Rima Kulikauskas, Christine H Chung, Uwe M Martens, Robert L Ferris, Julie E Stein, Elizabeth L Engle, Lot A Devriese, Christopher D Lao, Junchen Gu, Bin Li, Tian Chen, Adam Barrows, Andrea Horvath, Janis M Taube, Paul Nghiem,

<h4>Purpose</h4>Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer commonly driven by the Merkel cell polyomavirus (MCPyV). The programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) immunosuppressive pathway is often upregulated in MCC, and advanced metastatic MCC frequently responds to PD-1 blockade. We report what we believe to be the first ... Read more >>

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2020, 38(22):2476-2487]

Cited: 3 times

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Should Margin Status of Biopsies Be Included in Dermatopathology Reports? Clinician Preferences and the Importance of Unambiguous Language.

Emilie Jacobsen, Daniel S Hippe, Kristina Lachance, Marie E Perrone, Oliver H Chang, Michi M Shinohara,

Significant communication occurs between pathologists and clinicians through the dermatopathology report. Our objective was to describe clinician preference about reporting of the margin status of skin biopsies of nonmelanoma skin cancers. An anonymous survey was sent to 243 medical providers who submitted specimens to a single institution university medical center; ... Read more >>

Am J Dermatopathol (The American Journal of dermatopathology)
[2020, 42(3):186-190]

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Management of Cutaneous T-Cell Lymphoma/Mycosis Fungoides Occurring in the Setting of Solid Organ Transplantation: Report of 2 Cases.

David B Griffin, Tamar Hajar, Eric Simpson, Kevin P White, Michi M Shinohara,

Clin Lymphoma Myeloma Leuk (Clinical lymphoma, myeloma & leukemia)
[2020, 20(2):e39-e42]

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Dermatologist burnout: Contribution of gender and impact of children.

Olivia R Ware, Tyler D Coolman, Michi M Shinohara,

J Am Acad Dermatol (Journal of the American Academy of Dermatology)
[2020, 83(4):1178-1181]

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Racial limitations of fitzpatrick skin type.

Olivia R Ware, Jessica E Dawson, Michi M Shinohara, Susan C Taylor,

Fitzpatrick skin type (FST) was developed to assess the propensity of the skin to burn during phototherapy, but it also is commonly used by providers as means of describing constitutive skin color and ethnicity. We conducted an anonymous survey of dermatologists and dermatology trainees to evaluate how providers use FST ... Read more >>

Cutis (Cutis)
[2020, 105(2):77-80]

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A survey-based study of diagnostic and treatment concordance in standardized cases of cellulitis and pseudocellulitis via teledermatology.

Abraham M Korman, Daniela Kroshinsky, Adam B Raff, Arash Mostaghimi, Robert G Micheletti, Misha Rosenbach, Benjamin H Kaffenberger, ,

J Am Acad Dermatol (Journal of the American Academy of Dermatology)
[2020, 82(5):1221-1223]

Cited: 1 time

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Pralatrexate for refractory or recurrent subcutaneous panniculitis-like T-cell lymphoma with hemophagocytic syndrome.

Olivia Ware, Erica S Tarabadkar, Andrei Shustov, Michi M Shinohara,

J Am Acad Dermatol (Journal of the American Academy of Dermatology)
[2020, 82(2):489-491]

Cited: 0 times

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Characterisation and diagnosis of ulcers in inpatient dermatology consultation services: A multi-centre study.

Dylan Haynes, Phoebe Hammer, Stephen J Malachowski, Benjamin Kaffenberger, Jonathan S Yi, Nora Vera, Cody Calhoun, Michi M Shinohara, Lucia Seminario-Vidal, John C Trinidad, Jesse J Keller, Alex G Ortega-Loayza,

Accurate and prompt diagnosis of skin ulcers is critical to optimise management; however, studies in hospitalised patients are limited. This retrospective review of dermatologic consultations included 272 inpatients with skin ulcers between July 2015 and July 2018 in four U.S. academic hospitals. The median age was 54 years and 45% were ... Read more >>

Int Wound J (International wound journal)
[2019, 16(6):1440-1444]

Cited: 1 time

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Sexual harassment from patient to provider.

Eliza Notaro, Vanessa Pascoe, Michi M Shinohara, Katherine DeNiro,

Int J Womens Dermatol (International journal of women's dermatology)
[2020, 6(1):30-31]

Cited: 0 times

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Barriers and job satisfaction among dermatology hospitalists.

Jake C Robertson, Maryam Safaee, Fan Liu, Michi M Shinohara,

Dermatology hospitalists (DHs) provide consultative care to inpatients with skin conditions. In this study, we surveyed current members of the Society for Dermatology Hospitalists (SDH) regarding barriers to care, current and ideal compensation models, and overall job satisfaction to evaluate the overall job satisfaction of DHs and further describe potential ... Read more >>

Cutis (Cutis)
[2019, 104(2):103-105]

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Utility of Skin Biopsy and Culture in the Diagnosis and Classification of Chronic Ulcers: A Single-Institution, Retrospective Study.

Shiva Khoobyari, Timothy I Miller, Michi M Shinohara,

In the United States, chronic ulcers affect 6.5 million people, with a cost of ≈$20 million annually. The most common etiology of chronic ulcers in the United States is venous stasis, followed by arterial insufficiency and neuropathic ulcers. Less common causes of chronic ulcers include infection, inflammatory etiologies such as ... Read more >>

Am J Dermatopathol (The American Journal of dermatopathology)
[2019, 41(5):343-346]

Cited: 0 times

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Cutaneous manifestations of angioimmunoblastic T-cell lymphoma.

Sidney Hoskins, Natalie Moriarty, Kevin White, Andrea Kalus, Andrei Shustov, Michi M Shinohara,

Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkin lymphoma often accompanied by autoimmune and paraneoplastic phenomena. Up to 50% of patients with AITL present with skin manifestations. This case series highlights two cases of AITL presenting with unusual cutaneous findings: one with a medium-vessel vasculitis and another with ... Read more >>

Dermatol Online J (Dermatology online journal)
[2019, 25(7):]

Cited: 0 times

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How I treat primary cutaneous CD30+ lymphoproliferative disorders.

Michi M Shinohara, Andrei Shustov,

The primary cutaneous CD30<sup>+</sup> lymphoproliferative disorders are a family of extranodal lymphoid neoplasms that arise from mature postthymic T cells and localize to the skin. Current classification systems recognize lymphomatoid papulosis (LyP), primary cutaneous anaplastic large cell lymphoma, and borderline cases. In the majority of patients, the prognosis of primary ... Read more >>

Blood (Blood)
[2019, 134(6):515-524]

Cited: 1 time

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Skin Directed Therapy in Cutaneous T-Cell Lymphoma.

Erica S Tarabadkar, Michi M Shinohara,

Skin directed therapies (SDTs) serve important roles in the treatment of early stage cutaneous T-cell lymphoma (CTCL)/mycosis fungoides (MF), as well as managing symptoms and improving quality of life of all stages. There are now numerous options for topical therapies that demonstrate high response rates, particularly in early/limited MF. Phototherapy ... Read more >>

Front Oncol (Frontiers in oncology)
[2019, 9:260]

Cited: 3 times

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Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy.

Paul Nghiem, Shailender Bhatia, Evan J Lipson, William H Sharfman, Ragini R Kudchadkar, Andrew S Brohl, Phillip A Friedlander, Adil Daud, Harriet M Kluger, Sunil A Reddy, Brian C Boulmay, Adam I Riker, Melissa A Burgess, Brent A Hanks, Thomas Olencki, Kim Margolin, Lisa M Lundgren, Abha Soni, Nirasha Ramchurren, Candice Church, Song Y Park, Michi M Shinohara, Bob Salim, Janis M Taube, Steven R Bird, Nageatte Ibrahim, Steven P Fling, Blanca Homet Moreno, Elad Sharon, Martin A Cheever, Suzanne L Topalian,

PURPOSE:Merkel cell carcinoma (MCC) is an aggressive skin cancer often caused by the Merkel cell polyomavirus. Clinical trials of programmed cell death-1 pathway inhibitors for advanced MCC (aMCC) demonstrate increased progression-free survival (PFS) compared with historical chemotherapy data. However, response durability and overall survival (OS) data are limited. PATIENTS AND ... Read more >>

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2019, 37(9):693-702]

Cited: 38 times

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The management of numerous carcinomatous sequelae of human papilloma virus in an allogeneic stem cell transplant patient with chronic graft versus host disease.

Amanda Williams, Courtney Gwinn, Jayasri Iyer, Philip Fleckman, Michi M Shinohara,

JAAD Case Rep (JAAD case reports)
[2019, 5(2):162-166]

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Generalized fixed drug eruption mimicking CD8+ cutaneous T-cell lymphoma in HIV.

Emilie Jacobsen, Erica S Tarabadkar, Michi M Shinohara,

We present a case of a widespread fixed drug eruption histologically mimicking CD8 positive cutaneous T-cell lymphoma (CTCL). CTCL has several potential histological and clinical mimics, and accurate diagnosis relies on a combination of clinicopathological correlation and molecular studies. We add generalized fixed drug eruption to the list of possible ... Read more >>

J Cutan Pathol (Journal of cutaneous pathology)
[2019, 46(2):134-137]

Cited: 0 times

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Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy.

Natalie J Miller, Candice D Church, Steven P Fling, Rima Kulikauskas, Nirasha Ramchurren, Michi M Shinohara, Harriet M Kluger, Shailender Bhatia, Lisa Lundgren, Martin A Cheever, Suzanne L Topalian, Paul Nghiem,

<h4>Background</h4>Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus (MCPyV). MCPyV-specific T and B cell responses provide a unique opportunity to study cancer-specific immunity throughout PD-1 blockade therapy.<h4>Methods</h4>Immune responses were ... Read more >>

J Immunother Cancer (Journal for immunotherapy of cancer)
[2018, 6(1):131]

Cited: 3 times

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Panniculitis in a patient with pathologic complete response to talimogene laherparepvec treatment for recurrent, in-transit melanoma.

Thomas H Long, Michi M Shinohara, Zsolt B Argenyi, John A Thompson, Jennifer M Gardner,

Talimogene laherparepvec (T-VEC) is a novel intralesional oncolytic genetically modified herpes simplex virus type 1 vector for the treatment of unresectable cutaneous, subcutaneous, and nodal melanoma. Although immunological therapies such as T-VEC offer therapeutic promise, they carry a risk of immune-related adverse events (irAEs), the full spectrum of which is ... Read more >>

J Cutan Pathol (Journal of cutaneous pathology)
[2018, 45(11):864-868]

Cited: 0 times

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Optical coherence tomography angiography of normal skin and inflammatory dermatologic conditions.

Anthony J Deegan, Faezeh Talebi-Liasi, Shaozhen Song, Yuandong Li, Jingjiang Xu, Shaojie Men, Michi M Shinohara, Mary E Flowers, Stephanie J Lee, Ruikang K Wang,

BACKGROUND:In clinical dermatology, the identification of subsurface vascular and structural features known to be associated with numerous cutaneous pathologies remains challenging without the use of invasive diagnostic tools. OBJECTIVE:To present an advanced optical coherence tomography angiography (OCTA) method to directly visualize capillary-level vascular and structural features within skin in vivo. ... Read more >>

Lasers Surg Med (Lasers in surgery and medicine)
[2018, 50(3):183-193]

Cited: 12 times

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Assessment of risk and use of prophylaxis for glucocorticoidinduced-osteoporosis among dermatologists in the Pacific Northwest: a survey study.

Eliza Notaro, Nicole Fett, Michi M Shinohara,

Exposure to even physiologic doses of glucocorticoids can reduce one's bone mass and increase risk for osteoporotic fracture. There currently exists a wide variation in clinician approach to the assessment and management of glucocorticoid-induced osteoporosis (GIO). Our objectives were to characterize Pacific Northwest dermatology providers' general practices, assessment of risk ... Read more >>

Dermatol Online J (Dermatology online journal)
[2017, 23(9):]

Cited: 0 times

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Invasive Trichophyton rubrum mimicking blastomycosis in a patient with solid organ transplant.

Faezeh Talebi-Liasi, Michi M Shinohara,

We present a case of tissue invasive Trichophyton rubrum (T. rubrum) histologically mimicking blastomycosis in a patient with kidney transplant on chronic immunosuppression. Invasive dermatophyte infections are rare, and present a diagnostic challenge to the dermatopathologist due to atypical clinical and histopathological presentations. ... Read more >>

J Cutan Pathol (Journal of cutaneous pathology)
[2017, 44(9):798-800]

Cited: 1 time

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