Full Text Journal Articles by
Author Michel Rivoire

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Fast and Selective Ablation of Liver Tumors by High-Intensity Focused Ultrasound Using a Toroidal Transducer Guided by Ultrasound Imaging: The Results of Animal Experiments.

Amélie Battais, Victor Barrère, W Apoutou N'Djin, Aurélien Dupré, Michel Rivoire, David Melodelima,

This study demonstrated that high-intensity focused ultrasound (HIFU) produced with an intra-operative toroidal-shaped transducer causes fast, selective liver tumor ablations in an animal model. The HIFU device is composed of 256 emitters working at 3 MHz. A 7.5 MHz ultrasound imaging probe centered on the HIFU transducer guided treatment. VX2 ... Read more >>

Ultrasound Med Biol (Ultrasound in medicine & biology)
[2020, :]

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20-year assessment of metastatic latency and subsequent time to death after proton therapy for uveal melanomas.

David Bellocq, Pascal Roy, Laurent Kodjikian, Thibaud Mathis, Anh-Minh Nguyen, Joël Herault, Michel Rivoire, Sylvie Négrier, Juliette Thariat, Jean-Daniel Grange,

The aim of this study was to evaluate metastatic latency and survival after the occurrence of metastases in patients with choroidal/ciliary body melanoma treated with proton therapy. This was a retrospective cohort study. All consecutive patients with choroidal/ciliary body melanoma treated with proton therapy between 1991 and 2010 were included. ... Read more >>

Melanoma Res. (Melanoma research)
[2020, 30(3):272-278]

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Two-dimensional-cultures of primary human hepatocytes allow efficient HBV infection: Old tricks still work!

Julie Lucifora, Maud Michelet, Michel Rivoire, Ulrike Protzer, David Durantel, Fabien Zoulim,

J. Hepatol. (Journal of hepatology)
[2020, 73(2):449-451]

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[French Society for Surgical Oncology (SFCO) guidelines for the management of surgical oncology in the pandemic context of COVID 19].

Jean-Marc Classe, Gilles Dolivet, Serge Evrard, Gwenael Ferron, Fabrice Lécuru, Lea Leufflen, Michel Rivoire, Olivia Sgarbura,

Bull Cancer (Bulletin du cancer)
[2020, 107(5):524-527]

Cited: 1 time

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Organ preservation with chemoradiotherapy plus local excision for rectal cancer: 5-year results of the GRECCAR 2 randomised trial.

Eric Rullier, Véronique Vendrely, Julien Asselineau, Philippe Rouanet, Jean-Jacques Tuech, Alain Valverde, Cecile de Chaisemartin, Michel Rivoire, Bertrand Trilling, Mehrdad Jafari, Guillaume Portier, Bernard Meunier, Igor Sieleznieff, Martin Bertrand, Frédéric Marchal, Anne Dubois, Marc Pocard, Anne Rullier, Denis Smith, Nora Frulio, Eric Frison, Quentin Denost,

BACKGROUND:GRECCAR 2 was the first multicentre, randomised trial to compare local excision with total mesorectal excision in downstaged low rectal cancer. Encouraging oncological results were noted at 3 years' follow-up but needed to be corroborated with longer follow-up. In this study, we aimed to report the 5-year oncological outcomes, including ... Read more >>

Lancet Gastroenterol Hepatol (The lancet. Gastroenterology & hepatology)
[2020, 5(5):465-474]

Cited: 1 time

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In vitro transformation of primary human hepatocytes: Epigenetic changes and stemness properties.

Floriane Pez, Patricia Gifu, Davide Degli-Esposti, Nadim Fares, Anaïs Lopez, Lydie Lefrançois, Maud Michelet, Michel Rivoire, Brigitte Bancel, Bakary S Sylla, Zdenko Herceg, Philippe Merle, Claude Caron de Fromentel,

Human hepatocarcinogenesis is a complex process with many unresolved issues, including the cell of origin (differentiated and/or progenitor/stem cells) and the initial steps leading to tumor development. With the aim of providing new tools for studying hepatocellular carcinoma initiation and progression, we developed an innovative model based on primary human ... Read more >>

Exp. Cell Res. (Experimental cell research)
[2019, 384(2):111643]

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Systemic chemotherapy plus cetuximab after complete surgery in the treatment of isolated colorectal peritoneal carcinoma: COCHISE phase II clinical trial.

Serge Evrard, Grégoire Desolneux, Carine Bellera, Thomas Esnaud, Yves Bécouarn, Denis Collet, Najim Chafai, Francois Marchal, Laurent Cany, Emilie Lermite, Michel Rivoire, Simone Mathoulin-Pélissier,

OBJECTIVE:The primary objective of this non-randomised phase II study was to evaluate the combination of systemic chemotherapy plus cetuximab after complete cytoreductive surgery (CCS) for treatment of isolated colorectal peritoneal carcinoma (CRPC). This multicentre, prospective phase II clinical trial was conducted in seven national cancer referral centres, however research published ... Read more >>

BMC Res Notes (BMC research notes)
[2019, 12(1):450]

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Circulating Tumor Cells and Circulating Tumor DNA Detection in Potentially Resectable Metastatic Colorectal Cancer: A Prospective Ancillary Study to the Unicancer Prodige-14 Trial.

François-Clément Bidard, Nicolas Kiavue, Marc Ychou, Luc Cabel, Marc-Henri Stern, Jordan Madic, Adrien Saliou, Aurore Rampanou, Charles Decraene, Olivier Bouché, Michel Rivoire, François Ghiringhelli, Eric Francois, Rosine Guimbaud, Laurent Mineur, Faiza Khemissa-Akouz, Thibault Mazard, Driffa Moussata, Charlotte Proudhon, Jean-Yves Pierga, Trevor Stanbury, Simon Thézenas, Pascale Mariani,

The management of patients with colorectal cancer (CRC) and potentially resectable liver metastases (LM) requires quick assessment of mutational status and of response to pre-operative systemic therapy. In a prospective phase II trial (NCT01442935), we investigated the clinical validity of circulating tumor cell (CTC) and circulating tumor DNA (ctDNA) detection. ... Read more >>

Cells (Cells)
[2019, 8(6):]

Cited: 2 times

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Building a collaboration to improve surgical research through EORTC/ESSO 1409-CLIMB study: A prospective liver metastasis database with an integrated quality assurance program.

Carmela Caballero, Susen Burock, Lucia Carrion-Alvarez, Henrik Nilsson, Theo Ruers, Perrine Senellart, Michel Rivoire, Stefan Stattner, Florian Primavesi, Roberto Troisi, Thomas Gruenberger, Jan Heil, Andreas A Schnitzbauer, Nuh N Rahbari, Rutger-Jan Swijnenburg, Hassan Malik, Mladjan Protic, Kozo Kataoka, Murielle Mauer, Michel Ducreux, Graeme Poston, Serge Evrard,

The challenges of conducting surgical oncology trials have resulted to low quantity and poor quality research [1,2]. Considering the definitive role of surgery to offer cure, immediate response to improve surgical research is needed [3]. The European Organization for Research and Treatment of Cancer (EORTC) and the European Society of ... Read more >>

Eur J Surg Oncol (European Journal of Surgical Oncology)
[2019, 45(10):1870-1875]

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Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer With Peritoneal Metastases (CYTO-CHIP study): A Propensity Score Analysis.

Pierre-Emmanuel Bonnot, Guillaume Piessen, Vahan Kepenekian, Evelyne Decullier, Marc Pocard, Bernard Meunier, Jean-Marc Bereder, Karine Abboud, Frédéric Marchal, François Quenet, Diane Goere, Simon Msika, Catherine Arvieux, Nicolas Pirro, Romuald Wernert, Patrick Rat, Johan Gagnière, Jeremie H Lefevre, Thomas Courvoisier, Reza Kianmanesh, Delphine Vaudoyer, Michel Rivoire, Pierre Meeus, Guillaume Passot, Olivier Glehen, ,

PURPOSE:Gastric cancer (GC) with peritoneal metastases (PMs) is a poor prognostic evolution. Cytoreductive surgery (CRS) yields promising results, but the impact of hyperthermic intraperitoneal chemotherapy (HIPEC) remains controversial. Here we aimed to compare outcomes between CRS-HIPEC versus CRS alone (CRSa) among patients with PMs from GC. PATIENTS AND METHODS:From prospective ... Read more >>

J. Clin. Oncol. (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2019, 37(23):2028-2040]

Cited: 9 times

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A 96-hour continuous wound infiltration with ropivacaine reduces analgesic consumption after liver resection: A randomized, double-blind, controlled trial.

Véronique Peres-Bachelot, Ellen Blanc, Nadia Oussaid, David Pérol, Anne Laure Daunizeau-Walker, Stéphanie Pouderoux, Patrice Peyrat, Michel Rivoire, Aurélien Dupré,

BACKGROUND:Continuous wound infiltration (CWI) with local anesthetics to reduce morphine consumption in postoperative pain management after open liver resection in patients with cancer. METHODS:This single-center randomized double-blind study allocated patients requiring resection of liver metastases to receive a 3.75 mg/mL ropivacaine (ROP) infiltration, followed by a 2 mg/mL ROP CWI, or placebo ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2019, 119(1):47-55]

Cited: 0 times

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Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases.

Aurélien Dupre, David Melodelima, David Perol, Yao Chen, Jérémy Vincenot, Jean-Yves Chapelon, Michel Rivoire,

Today, the only potentially curative option in patients with colorectal liver metastases is surgery. However, liver resection is feasible in less than 20% of patients. Surgery has been widely used in association with radiofrequency, cryotherapy, or microwaves to expand the number of treatments performed with a curative intent. Nevertheless, several ... Read more >>

J Vis Exp (Journal of visualized experiments : JoVE)
[2019, (143):]

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Primary Tumor Versus Liver-First Approach for Synchronous Colorectal Liver Metastases: An Association Française de Chirurgie (AFC) Multicenter-Based Study with Propensity Score Analysis.

Francesco Esposito, Chetana Lim, Antonio Sa Cunha, Patrick Pessaux, Francis Navarro, Daniel Azoulay, ,

OBJECTIVES:Multicenter studies comparing the reverse strategy (RS) with the classical strategy (CS) for the management of stage IVA liver-only colorectal cancer (CCR) are scarce. The aim of this study was to compare long-term survival and recurrence patterns following use of the CS and RS. METHOD:This retrospective multicenter review collected data ... Read more >>

World J Surg (World journal of surgery)
[2018, 42(12):4046-4053]

Cited: 2 times

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Major Hepatectomy for Colorectal Liver Metastases in Patients Aged Over 80: A Propensity Score Matching Analysis.

Vito De Blasi, Riccardo Memeo, René Adam, Diane Goéré, Daniel Cherqui, Jean Marc Regimbeau, Michel Rivoire, Laura Ornella Perotto, Francis Navarro, Antonio Sa Cunha, Patrick Pessaux, ,

BACKGROUND:The aim of this study was to evaluate the results of major hepatectomies for metastasis in elderly colorectal cancer patients, for whom limited data exist in the literature. METHODS:From January 2006 to January 2013, 3,034 patients underwent hepatectomy for colorectal liver metastasis in 32 French surgical centers. Repeat hepatectomies were ... Read more >>

Dig Surg (Digestive surgery)
[2018, 35(4):333-341]

Cited: 2 times

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Margin Status is Still an Important Prognostic Factor in Hepatectomies for Colorectal Liver Metastases: A Propensity Score Matching Analysis.

Riccardo Memeo, Vito de Blasi, Rene Adam, Diane Goéré, Tullio Piardi, Emilie Lermite, Olivier Turrini, Francis Navarro, Nicola de'Angelis, Antonio Sa Cunha, Patrick Pessaux, ,

OBJECTIVE:The width of resection margin is still a matter of debate in case of colorectal liver metastasis resection. The aim of this study was to determine the risk factors for R1 resection. Once risk factors had been identified, patients were matched according to Fong's prognostic criteria, in order to evaluate ... Read more >>

World J Surg (World journal of surgery)
[2018, 42(3):892-901]

Cited: 8 times

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HEPATOFLUO: A prospective monocentric study assessing the benefits of indocyanine green (ICG) fluorescence for hepatic surgery.

Patrice Peyrat, Ellen Blanc, Stéphanie Guillermet, Yao Chen, Céline Ferlay, David Perol, Valéria Basso, Michel Rivoire, Aurélien Dupré,

Fluorescence imaging using indocyanine green (ICG) is undergoing extensive development. This study aimed to assess the merits of ICG in regard to hepatic surgery.Patients with liver lesions that required a resection were eligible. They received an injection of ICG the day before the surgery. Step 1 allowed assessment of use ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2018, 117(5):922-927]

Cited: 2 times

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CRP Predicts Safe Patient Discharge After Colorectal Surgery.

Aurélien Dupré, Johan Gagnière, Heloïse Samba, Michel Rivoire, Karem Slim,

Ann. Surg. (Annals of surgery)
[2018, 267(2):e33]

Cited: 0 times

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Laparoscopic Compared to Open Repeat Hepatectomy for Colorectal Liver Metastases: a Multi-institutional Propensity-Matched Analysis of Short- and Long-Term Outcomes.

Julie Hallet, Antonio Sa Cunha, Daniel Cherqui, Brice Gayet, Diane Goéré, Philippe Bachellier, Alexis Laurent, David Fuks, Francis Navarro, Patrick Pessaux, ,

INTRODUCTION:While uptake of laparoscopic hepatectomy has improved, evidence on laparoscopic re-hepatectomy (LRH) for colorectal liver metastases (CRLMs) is limited and has never been compared to the open approach. We sought to define outcomes of LRH compared to open re-hepatectomy (ORH). METHODS:Patients undergoing re-hepatectomy for CRLM at 39 institutions (2006-2013) were ... Read more >>

World J Surg (World journal of surgery)
[2017, 41(12):3189-3198]

Cited: 4 times

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Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes.

Romain Barnault, Thomas Lahlali, Marie-Laure Plissonnier, Cristina Romero-López, Noémie Laverdure, Benjamin Ducarouge, Michel Rivoire, Patrick Mehlen, Fabien Zoulim, Romain Parent,

In the liver, HBV and HCV infections, exposure to toxics, genetic and metabolic disorders may induce endoplasmic reticulum (ER) stress and the unfolding protein response (UPR). The UPR allows cells to reach ER homeostasis after lumen overload, but also fosters survival of damaged cells and therefore HCC onset. Dependence receptors ... Read more >>

Biochem. Biophys. Res. Commun. (Biochemical and biophysical research communications)
[2018, 495(4):2425-2431]

Cited: 1 time

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Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial.

Eric Rullier, Philippe Rouanet, Jean-Jacques Tuech, Alain Valverde, Bernard Lelong, Michel Rivoire, Jean-Luc Faucheron, Mehrdad Jafari, Guillaume Portier, Bernard Meunier, Igor Sileznieff, Michel Prudhomme, Frédéric Marchal, Marc Pocard, Denis Pezet, Anne Rullier, Véronique Vendrely, Quentin Denost, Julien Asselineau, Adélaïde Doussau,

BACKGROUND:Organ preservation is a concept proposed for patients with rectal cancer after a good clinical response to neoadjuvant chemotherapy, to potentially avoid morbidity and side-effects of rectal excision. The objective of this study was to compare local excision and total mesorectal excision in patients with a good response after chemoradiotherapy ... Read more >>

Lancet (Lancet (London, England))
[2017, 390(10093):469-479]

Cited: 37 times

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Thermal Ablation of the Pancreas With Intraoperative High-Intensity Focused Ultrasound: Safety and Efficacy in a Porcine Model.

Aurélien Dupré, David Melodelima, Hannah Pflieger, Yao Chen, Jérémy Vincenot, Anthony Kocot, Stéphan Langonnet, Michel Rivoire,

New focal destruction technologies such as high-intensity focused ultrasound (HIFU) may improve the prognosis of pancreatic ductal adenocarcinoma. Our objectives were to demonstrate the safety and efficacy of intraoperative pancreatic HIFU ablation in a porcine model.In a porcine model (N = 12), a single HIFU ablation was performed in either ... Read more >>

Pancreas (Pancreas)
[2017, 46(2):219-224]

Cited: 2 times

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Efficacy of high-intensity focused ultrasound-assisted hepatic resection (HIFU-AR) on blood loss reduction in patients with liver metastases requiring hepatectomy: study protocol for a randomized controlled trial.

Aurélien Dupré, David Pérol, Ellen Blanc, Patrice Peyrat, Valéria Basso, Yao Chen, Jérémy Vincenot, Anthony Kocot, David Melodelima, Michel Rivoire,

Liver resection is the only potentially curative treatment for colorectal liver metastases (LM). It is considered a safe procedure, but is often associated with blood loss during liver transection. Blood transfusions are frequently needed, but they are associated with increased morbidity and risk of recurrence. Many surgical devices have been ... Read more >>

Trials (Trials)
[2017, 18(1):57]

Cited: 0 times

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Portal supply of segment IV of the liver based on CT-scan.

Roxane Maurer, Michel Rivoire, Valéria Basso, Pierre Meeus, Patrice Peyrat, Aurélien Dupré,

The portal vascularization of segment IV (S4) of the liver has not been well described. Knowledge of the portal supply to S4 is of great interest for liver surgery and for interventional radiological procedures. This study aimed to analyse the distribution of portal vein branches supplying S4.We retrospectively analysed data ... Read more >>

Surg Radiol Anat (Surgical and radiologic anatomy : SRA)
[2017, 39(5):471-476]

Cited: 1 time

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Identification of intra-hepatic communicating veins through the arch sign on CT-scan.

Alexandre Morel, Michel Rivoire, Valéria Basso, Pierre Meeus, Patrice Peyrat, Aurélien Dupré,

Knowledge of vascular outflow is essential in liver surgery. Communicating veins between the right hepatic vein (RHV) and the middle hepatic vein (MHV) have been described and allowed us to perform new surgical procedures. The aim of this study was to predict the existence of intra-hepatic venous anastomosis by identifying ... Read more >>

Surg Radiol Anat (Surgical and radiologic anatomy : SRA)
[2017, 39(6):673-677]

Cited: 0 times

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Outcomes of Rehepatectomy for Colorectal Liver Metastases: A Contemporary Multi-Institutional Analysis from the French Surgical Association Database.

Julie Hallet, Antonio Sa Cunha, Rene Adam, Diane Goéré, Daniel Azoulay, Jean-Yves Mabrut, Fabrice Muscari, Christophe Laurent, Francis Navarro, Patrick Pessaux, ,

Recurrence remains frequent after curative-intent hepatectomy for colorectal liver metastases (CRLM). We sought to define short- and long-term outcomes, and identify prehepatectomy factors associated with survival, following rehepatectomy (RH) for recurrence.We conducted a multi-institutional cohort study of hepatectomy for CRLM over 2006-2013. Second-stage resections were excluded. Primary outcomes were overall ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2016, 23(Suppl 5):894-903]

Cited: 4 times

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