Full Text Journal Articles by
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Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply.

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton,

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(9):1215-1216]

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Turning the tide on hepatitis C-related liver transplantation: the return on investment in hepatitis C treatment in Australia and New Zealand.

Jess Howell, Avik Majumdar, Michael Fink, Mandy Byrne, Geoff McCaughan, Simone I Strasser, Michael Crawford, Peter Hodgkinson, Katherine A Stuart, Caroline Tallis, John Chen, Alan Wigg, Robert Jones, Bryon Jaques, Gary Jeffrey, Leon Adams, Michael C Wallace, Stephen Munn, Ed Gane, Alex Thompson, Paul Gow,

<h4>Background</h4>Introduction of universal access to direct-acting antiviral therapy (DAAs) for hepatitis C (HCV) in Australia and New Zealand on March 31<sup>st</sup> 2016 has had a major impact on the number of people with chronic HCV infection, but the impact on liver transplantation rates is unknown.<h4>Methods</h4>We conducted a retrospective registry study ... Read more >>

Liver Transpl (Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society)
[2021, :]

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Serum fibrosis tests guide prognosis in metabolic dysfunction associated fatty liver disease patients referred from primary care.

Zhengyi Wang, Luis Calzadilla Bertot, Gary P Jeffrey, John Joseph, George Garas, Bastiaan de Boer, Yi Huang, Gerry MacQuillan, Michael Wallace, Briohny Smith, Leon A Adams,

<h4>Background and aims</h4>Metabolic dysfunction-associated fatty liver disease (MAFLD) is predominately managed in primary care, however there is uncertainty regarding how to best identify patients for specialist referral. We examined the accuracy of non-invasive tests (NITs) as screening tools for the prediction of outcomes in MAFLD patients referred from primary care.<h4>Methods</h4>Patients ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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The Great Recession Index: A Place-based Indicator for Countries, States, and Metropolitan Areas.

Michael Wallace, Angran Li, Allen Hyde,

The Great Recession (GR) of 2007-2009 marked the most devastating economic downturn since the Great Depression of the 1930s, and its consequences dramatically changed almost every aspect of social life. This research introduces the Great Recession Index (GRI), a place-based composite measure that captures the multidimensional nature of the GR. ... Read more >>

Soc Indic Res (Social indicators research)
[2021, :1-26]

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Herbicidal activity of fluoroquinolone derivatives.

Michael D Wallace, Aleksandra W Debowski, Kirill V Sukhoverkov, Joshua S Mylne, Keith A Stubbs,

Development of herbicides with novel modes of action is crucial for weed control and to hinder herbicide resistance. An attractive novel herbicidal target is plant DNA gyrase, which has been demonstrated to be effectively inhibited by the known antimicrobial ciprofloxacin. Despite this good herbicidal activity, ciprofloxacin is not suitable as ... Read more >>

Plant Direct (Plant direct)
[2021, 5(9):e348]

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Systemic anticoagulation is associated with decreased mortality and morbidity in acute pancreatitis.

Paul T Kröner, Michael B Wallace, Massimo Raimondo, Samuel O Antwi, Yaohua Ma, Zhuo Li, Baoan Ji, Yan Bi,

<h4>Background/objectives</h4>Acute pancreatitis (AP) is a procoagulant state, and markers of coagulopathy are associated with AP severity. We aimed to explore the association of systemic anticoagulation therapy before AP onset with the inpatient outcomes of patients with acute pancreatitis.<h4>Methods</h4>This case-control, retrospective study used data from the Nationwide Inpatient Sample (Jan 2014-Dec ... Read more >>

Pancreatology (Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.])
[2021, :]

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Intestinal chemosensitivity in irritable bowel syndrome associates with small intestinal TRPV channel expression.

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton,

<h4>Background</h4>Irritable bowel syndrome (IBS) patients often experience meal-associated symptoms. However, the underlying mechanisms are unclear.<h4>Aim</h4>To determine small intestinal mechanisms of lipid-induced symptoms and rectal hypersensitivity in IBS METHODS: We recruited 26 IBS patients (12 IBS-C, 14 IBS-D) and 15 healthy volunteers (HV). In vivo permeability was assessed using saccharide excretion ... Read more >>

Aliment Pharmacol Ther (Alimentary pharmacology & therapeutics)
[2021, 54(9):1179-1192]

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An educational intervention to improve quality of care in Barrett's esophagus: the AQUIRE randomized controlled trial.

Sravanthi Parasa, Michael B Wallace, Sachin Srinivasan, Suneha Sundaram, Kevin F Kennedy, J Lucas Williams, Prateek Sharma,

Gastrointest Endosc (Gastrointestinal endoscopy)
[2021, :]

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Recommendations for a More Organized and Effective Approach to the Early Detection of Pancreatic Cancer From the PRECEDE (Pancreatic Cancer Early Detection) Consortium.

Tamas A Gonda, Jessica N Everett, Michael Wallace, Diane M Simeone, ,

Gastroenterology (Gastroenterology)
[2021, :]

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Reply to Krishna and Jain.

Mohammad Al-Haddad, Michael B Wallace,

Endoscopy (Endoscopy)
[2021, 53(9):988]

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Survey Finds Gender Disparities Impact Both Women Mentors and Mentees in Gastroenterology.

Loren Galler Rabinowitz, Lauren Tal Grinspan, Haley M Zylberberg, Rebekah Dixon, Yakira N David, Olga C Aroniadis, Austin Chiang, Jennifer Christie, Nabil F Fayad, Christina Ha, Lucinda A Harris, Cynthia W Ko, Jennifer Kolb, Joann Kwah, Linda Lee, David Lieberman, Laura E Raffals, Douglas K Rex, Shailja C Shah, Uzma D Siddiqui, Michael S Smith, Michael Wallace, Renee Williams, Karen Woods, Sheila E Crowe, Nikhil A Kumta, Michelle Kang Kim, David A Greenwald,

<h4>Introduction</h4>Gastroenterologists at all levels of practice benefit from formal mentoring. Much of the current literature on mentoring in gastroenterology is based on expert opinion rather than data. In this study, we aimed to identify gender-related barriers to successful mentoring relationships from the mentor and mentee perspectives.<h4>Methods</h4>A voluntary, web-based survey was ... Read more >>

Am J Gastroenterol (The American journal of gastroenterology)
[2021, 116(9):1876-1884]

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Computer-aided detection versus advanced imaging for detection of colorectal neoplasia: a systematic review and network meta-analysis.

Marco Spadaccini, Andrea Iannone, Roberta Maselli, Matteo Badalamenti, Madhav Desai, Viveksandeep Thoguluva Chandrasekar, Harsh K Patel, Alessandro Fugazza, Gaia Pellegatta, Piera Alessia Galtieri, Gianluca Lollo, Silvia Carrara, Andrea Anderloni, Douglas K Rex, Victor Savevski, Michael B Wallace, Pradeep Bhandari, Thomas Roesch, Ian M Gralnek, Prateek Sharma, Cesare Hassan, Alessandro Repici,

<h4>Background</h4>Computer-aided detection (CADe) techniques based on artificial intelligence algorithms can assist endoscopists in detecting colorectal neoplasia. CADe has been associated with an increased adenoma detection rate, a key quality indicator, but the utility of CADe compared with existing advanced imaging techniques and distal attachment devices is unclear.<h4>Methods</h4>For this systematic review ... Read more >>

Lancet Gastroenterol Hepatol (The lancet. Gastroenterology & hepatology)
[2021, 6(10):793-802]

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Exome Sequencing of Pancreatic Acinar Carcinoma Identified Distinctive Mutation Patterns.

Yuanhang Liu, Massimo Raimondo, Michael B Wallace, Kabir Mody, John A Stauffer, Lizhi Zhang, Baoan Ji, Yan Bi,

<h4>Objectives</h4>Pancreatic acinar cell carcinoma (ACC) is a rare pancreatic cancer. The advancement of treatment is hampered because of the limited knowledge of its molecular mechanism.<h4>Methods</h4>Whole-exome sequencing was performed on DNA extracted from 11 pure ACC surgical samples. Potential germline variants were removed on the basis of polymorphic databases, alternative allele ... Read more >>

Pancreas (Pancreas)
[2021, 50(7):1007-1013]

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Artificial intelligence and colonoscopy experience: lessons from two randomised trials.

Alessandro Repici, Marco Spadaccini, Giulio Antonelli, Loredana Correale, Roberta Maselli, Piera Alessia Galtieri, Gaia Pellegatta, Antonio Capogreco, Sebastian Manuel Milluzzo, Gianluca Lollo, Dhanai Di Paolo, Matteo Badalamenti, Elisa Ferrara, Alessandro Fugazza, Silvia Carrara, Andrea Anderloni, Emanuele Rondonotti, Arnaldo Amato, Andrea De Gottardi, Cristiano Spada, Franco Radaelli, Victor Savevski, Michael B Wallace, Prateek Sharma, Thomas Rösch, Cesare Hassan,

<h4>Background and aims</h4>Artificial intelligence has been shown to increase adenoma detection rate (ADR) as the main surrogate outcome parameter of colonoscopy quality. To which extent this effect may be related to physician experience is not known. We performed a randomised trial with colonoscopists in their qualification period (AID-2) and compared ... Read more >>

Gut (Gut)
[2021, :]

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Viral transport media for COVID-19 testing.

Matthew J Mears, Michael J Wallace, Jacob S Yount, Lorri A Fowler, Penny S Jones, Peter J Mohler, Loren E Wold,

Precautionary measures of physical isolation, social distancing, and masks have all aided in controlling the spread of COVID-19. However, detection of the virus is crucial to implement isolation of infected individuals. This paper presents the innovative repurposing of lab materials, workspace, and personnel in response to the COVID-19-induced shutdown and ... Read more >>

MethodsX (MethodsX)
[2021, 8:101433]

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Pancreatic cyst dilemma: a case where genetic sequencing and immunohistochemistry impacted clinical decision making.

Megan M L Engels, Hassan M Ghoz, Jason T Lewis, Michele D Lewis, Michael B Wallace,

Gastrointest Endosc (Gastrointestinal endoscopy)
[2021, 94(4):865-866]

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Detection of Postcolonoscopy Colorectal Neoplasia by Multi-target Stool DNA.

Derek W Ebner, Jason D Eckmann, Kelli N Burger, Douglas W Mahoney, Jamie Bering, Allon Kahn, Eduardo A Rodriguez, David O Prichard, Michael B Wallace, Sunanda V Kane, Lila J Finney Rutten, Suryakanth R Gurudu, John B Kisiel,

<h4>Introduction</h4>Significant variability between colonoscopy operators contributes to postcolonoscopy colorectal cancers (CRCs). We aimed to estimate postcolonoscopy colorectal neoplasia (CRN) detection by multi-target stool DNA (mt-sDNA), which has not previously been studied for this purpose.<h4>Methods</h4>In a retrospective cohort of patients with +mt-sDNA and completed follow-up colonoscopy, positive predictive value (PPV) for ... Read more >>

Clin Transl Gastroenterol (Clinical and translational gastroenterology)
[2021, 12(6):e00375]

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Preclinical metabolism and disposition of an orally bioavailable macrocyclic FXIa inhibitor.

Silvi A Chacko, Wu Yang, Yufeng Wang, Yuan Tian, Yang Hong, Michael Wallace, Bonnie Wang, William R Ewing, Joseph M Luettgen, Yue-Zhong Shu, Lisa J Christopher,

FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species.The objectives of this study were to characterize the in vitro metabolism, determine circulating metabolites in pre-clinical species, and examine the disposition of the compound in a bile duct-cannulated rat study (BDC) study to inform ... Read more >>

Xenobiotica (Xenobiotica; the fate of foreign compounds in biological systems)
[2021, 51(8):933-948]

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Herbicidal activity of fluoroquinolone derivatives

Michael Wallace, Aleksandra Debowski, Kirill Sukhoverkov, Joshua Mylne, Keith Stubbs,

Development of herbicides with novel modes of action are crucial for weed control and to hinder herbicide resistance. An attractive novel herbicidal target is plant DNA gyrase, which has been demonstrated to be effectively inhibited by the known antimicrobial ciprofloxacin. Despite this good herbicidal activity ciprofloxacin is not suitable as ... Read more >>

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International Delphi Expert Consensus on Safe Return to Surgical and Endoscopic Practice: From the Coronavirus Global Surgical Collaborative.

Horacio J Asbun, Mohammad Abu Hilal, Filipe Kunzler, Domenech Asbun, Jaap Bonjer, Kevin Conlon, Nicolas Demartines, Liane S Feldman, Salvador Morales-Conde, Andrea Pietrabissa, Aurora D Pryor, Christopher M Schlachta, Patricia Sylla, Eduardo M Targarona, Yolanda Agra, Marc G Besselink, Mark Callery, Sean P Cleary, Luis De La Cruz, Philippe Eckert, Chad Evans, Ho-Seong Han, Daniel B Jones, Tong Joo Gan, Daniel Koch, Keith D Lillemoe, Davide Lomanto, Jeffrey Marks, Brent Matthews, John Mellinger, William Scott Melvin, Eduardo Moreno-Paquentin, Claudio Navarrete, Timothy M Pawlik, Patrick Pessaux, Walter Ricciardi, Steven Schwaitzberg, Paresh Shah, Joseph Szokol, Mark Talamini, Ricardo Torres, Alessandro Triboldi, Suthep Udomsawaengsup, Federica Valsecchi, Jean-Nicolas Vauthey, Michael Wallace, Steven D Wexner, Michael Zinner, Nader Francis,

<h4>Objective</h4>The aim of this work is to formulate recommendations based on global expert consensus to guide the surgical community on the safe resumption of surgical and endoscopic activities.<h4>Background</h4>The COVID-19 pandemic has caused marked disruptions in the delivery of surgical care worldwide. A thoughtful, structured approach to resuming surgical services is ... Read more >>

Ann Surg (Annals of surgery)
[2021, 274(1):50-56]

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Response.

Michael J Bartel, Omar Y Mousa, Michael B Wallace,

Gastrointest Endosc (Gastrointestinal endoscopy)
[2021, 93(6):1438-1439]

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Development of a Decellularized Porcine Esophageal Matrix for Potential Applications in Cancer Modeling.

Hersh Chaitin, Michael L Lu, Michael B Wallace, Yunqing Kang,

Many decellularized extracellular matrix-derived whole organs have been widely used in studies of tissue engineering and cancer models. However, decellularizing porcine esophagus to obtain decellularized esophageal matrix (DEM) for potential biomedical applications has not been widely investigated. In this study a modified decellularization protocol was employed to prepare a porcine ... Read more >>

Cells (Cells)
[2021, 10(5):]

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External validation of blue light imaging (BLI) criteria for the optical characterization of colorectal polyps by endoscopy experts.

Madhav Desai, Kevin Kennedy, Hiroyuki Aihara, Jacques Van Dam, Seth Gross, Gregory Haber, Heiko Pohl, Douglas Rex, John Saltzman, Amrita Sethi, Irving Waxman, Kenneth Wang, Michael Wallace, Alessandro Repici, Prateek Sharma,

<h4>Background and aim</h4>Recently, the BLI Adenoma Serrated International Classification (BASIC) system was developed by European experts to differentiate colorectal polyps. Our aim was to validate the BASIC classification system among the US-based endoscopy experts.<h4>Methods</h4>Participants utilized a web-based interactive learning system where the group was asked to characterize polyps using the ... Read more >>

J Gastroenterol Hepatol (Journal of gastroenterology and hepatology)
[2021, 36(10):2728-2734]

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1.3 μm wavelength tunable single-mode laser arrays based on slots.

Michael McDermott, Robert McKenna, Caolán Murphy, Dovydas Mickus, Hai-Zhong Weng, Sepideh Naimi, Qiaoyin Lu, Wei-Hua Guo, Michael Wallace, Nicolás Abadía, John F Donegan,

Two twelve-channel arrays based on surface-etched slot gratings, one with non-uniformly spaced slots and another with uniformly spaced slots are presented for laser operation in the O-band. A wavelength tuning range greater than 40 nm, with a side-mode suppression ratio (SMSR) > 40 dB over much of this range and ... Read more >>

Opt Express (Optics express)
[2021, 29(10):15802-15812]

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State of the Art: The Impact of Artificial Intelligence in Endoscopy 2020.

Jiyoung Lee, Michael B Wallace,

<h4>Purpose of review</h4>Recently numerous researchers have shown remarkable progress using convolutional neural network-based artificial intelligence (AI) for endoscopy. In this manuscript we aim to summarize recent AI impact on endoscopy.<h4>Recent findings</h4>AI for detecting colon polyps has been the most promising area for application of AI in endoscopy. Recent prospective randomized ... Read more >>

Curr Gastroenterol Rep (Current gastroenterology reports)
[2021, 23(5):7]

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