Full Text Journal Articles by
Author Michael Nerlich

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Treatment of severely open tibial fractures, non-unions, and fracture-related infections with a gentamicin-coated tibial nail-clinical outcomes including quality of life analysis and psychological ICD-10-based symptom rating.

Nike Walter, Daniel Popp, Viola Freigang, Michael Nerlich, Volker Alt, Markus Rupp,

<h4>Background</h4>Implant-associated infections depict a major challenge in orthopedics and trauma surgery putting a high burden on the patients and health care systems, strongly requiring improvement of infection prevention and of clinical outcomes. One strategy includes the usage of antimicrobial-coated implants. We evaluated outcomes after surgical treatment using a gentamicin-coated nail on ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):270]

Cited: 1 time

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Um den halben Erdball konferieren : Besucherrekorde auf digitalen deutsch-chinesischen Tagungen

Michael Nerlich,

(Orthopädie und Unfallchirurgie)
[2021, 11(2):22-23]

Cited: 0 times

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The AO trauma CPP bone infection registry: Epidemiology and outcomes of Staphylococcus aureus bone infection.

Mario Morgenstern, Christoph Erichsen, Matthias Militz, Zhao Xie, Jiachen Peng, James Stannard, Willem-Jan Metsemakers, Dirk Schaefer, Volker Alt, Kjeld Søballe, Michael Nerlich, Richard E Buckley, Michael Blauth, Michael Suk, Frankie Leung, Jorge D Barla, Kiminori Yukata, Bi Qing, Stephen L Kates,

Bone infection represents a serious complication of orthopedic surgery and Staphylococcus aureus is the most common pathogen. To improve the understanding of host-pathogen interaction, we developed a biospecimen registry (AO Trauma CPP Bone Infection Registry) to collect clinical data, bacterial isolates, and serum from patients with S. aureus bone infection. ... Read more >>

J Orthop Res (Journal of orthopaedic research : official publication of the Orthopaedic Research Society)
[2021, 39(1):136-146]

Cited: 5 times

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The AO Trauma CPP Bone Infection Registry: epidemiology and outcomes on Staphylococcus aureus infection in long bones and joints

Mario Morgenstern, Christoph Erichsen, Matthias Militz, Zhao Xie, Peng Jiachen Peng, James Stannard, Willem-Jan Metsemakers, Dirk Schaefer, Volker Alt, Kjeld Soballe, Michael Nerlich, Richard Buckley, Michael Blauth, Michael Suk, Frankie Leung, Jorge Barla, Kiminori Yukata, Bi Qing, Edward Schwarz, Stephen Kates,

<h4>Background: </h4> Bone infection is a serious complication associated with orthopedic surgery, and Staphylococcus aureus ( S. aureus ) is a common pathogen. As the optimal treatment requires an understanding of the patient-specific host-pathogen interaction, we developed a biospecimen registry (the AO Trauma CPP Bone Infection Registry ) to collect ... Read more >>

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Prevention of severe knee injuries in men's elite football by implementing specific training modules.

Werner Krutsch, Jennifer Lehmann, Petra Jansen, Peter Angele, Birgit Fellner, Leonard Achenbach, Volker Krutsch, Michael Nerlich, Volker Alt, Oliver Loose,

<h4>Purpose</h4>Injury prevention of knee injuries by means of training and warm-up exercises has been investigated in several studies in amateur football. However, the number of investigations in elite football is limited despite the currently higher injury incidence of severe knee injuries. Therefore, the purpose of this study was to investigate ... Read more >>

Knee Surg Sports Traumatol Arthrosc (Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA)
[2020, 28(2):519-527]

Cited: 3 times

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Functional Deficits in the Wrist and Finger Joints of Goalkeepers After 20 Years of Playing Recreational Football.

Franz Hilber, Alexander Wiesenberg, Maximilian Kerschbaum, Antonio Ernstberger, Michael Worlicek, Michael Nerlich, Lukas Prantl, Matthias Koch, Volker Krutsch, Werner Krutsch,

<h4>Background</h4> Long-term damage in the hip, knee and ankle joints of football players has been thoroughly discussed in the literature. Compared with outfield players, however, goalkeepers sustain injuries to the upper extremities five times more often. There is a lack of studies on long-term functional damage to the wrist and finger ... Read more >>

Sportverletz Sportschaden (Sportverletzung Sportschaden : Organ der Gesellschaft fur Orthopadisch-Traumatologische Sportmedizin)
[2019, 33(3):142-148]

Cited: 1 time

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Risk factor analysis for delayed union after subtrochanteric femur fracture: quality of reduction and valgization are the key to success.

Viola Freigang, Franziska Gschrei, Himanshu Bhayana, Paul Schmitz, Johannes Weber, Maximilian Kerschbaum, Michael Nerlich, Florian Baumann,

<h4>Background</h4>Subtrochanteric femur fractures (SFF) are uncommon, but have a high complication rate concerning non-union and mechanical complications. There is ongoing discussion about risk factors for delayed fracture healing after SFF. The purpose of this study was to evaluate potential risk factors for delayed fracture healing after SFF.<h4>Methods</h4>This retrospective radio-morphometric case ... Read more >>

BMC Musculoskelet Disord (BMC musculoskeletal disorders)
[2019, 20(1):391]

Cited: 2 times

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Comprehensive treatment algorithm for atlanto-axial rotatory fixation (AARF) in children.

Daniel Mahr, Viola Freigang, Himanshu Bhayana, Maximilian Kerschbaum, Borys Frankewycz, Markus Loibl, Michael Nerlich, Florian Baumann,

<h4>Background</h4>Atlanto-axial rotatory fixation (AARF) is an uncommon condition in children presenting with torticollis. Many studies have elaborated on the diagnostic sequence of AARF. However, there is no consensus for the algorithm of management of AARF.<h4>Methods</h4>This study proposes to provide a comprehensive step-by-step guideline which aims to achieve and retain anatomic ... Read more >>

Eur J Trauma Emerg Surg (European journal of trauma and emergency surgery : official publication of the European Trauma Society)
[2021, 47(3):713-718]

Cited: 0 times

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Long-term outcome after surgical treatment of intra-articular tibial plateau fractures in skiers.

Martin Bäumlein, Alexander Hanke, Boyko Gueorguiev, Michael Nerlich, Emmanouil Liodakis, Thomas Perren, Paavo Rillmann, Christian Ryf, Markus Loibl,

<h4>Introduction</h4>Tibial plateau fractures occur frequently during downhill skiing. There is a lack of information about the outcome and development of posttraumatic osteoarthritis after internal fixation of such fractures at long-term follow-up in skiers.<h4>Materials and methods</h4>A population of 83 skiers was followed up in a case series after internal fixation of ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2019, 139(7):951-959]

Cited: 3 times

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Bone Marrow Aspirate Concentrate for the Treatment of Avascular Meniscus Tears in a One-Step Procedure-Evaluation of an In Vivo Model.

Matthias Koch, Selma Hammer, Julian Fuellerer, Siegmund Lang, Christian G Pfeifer, Girish Pattappa, Johannes Weber, Markus Loibl, Michael Nerlich, Peter Angele, Johannes Zellner,

Avascular meniscus tears show poor intrinsic regenerative potential. Thus, lesions within this area predispose the patient to developing knee osteoarthritis. Current research focuses on regenerative approaches using growth factors or mesenchymal stem cells (MSCs) to enhance healing capacity within the avascular meniscus zone. The use of MSCs especially as progenitor ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 20(5):]

Cited: 3 times

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TGF-β Signalling is Suppressed under Pro-Hypertrophic Conditions in MSC Chondrogenesis Due to TGF-β Receptor Downregulation.

Christian G Pfeifer, Alexandra Karl, Maximilian Kerschbaum, Arne Berner, Siegmund Lang, Rupert Schupfner, Matthias Koch, Peter Angele, Michael Nerlich, Michael B Mueller,

Background and Objectives:Mesenchymal stem cells (MSCs) become hypertrophic in long term despite chondrogenic differentiation following the pathway of growth plate chondrocytes. This terminal differentiation leads to phenotypically unstable cartilage and was mirrored in vitro by addition of hypertrophy inducing medium. We investigated how intrinsic TGF-β signaling is altered in pro-hypertrophic ... Read more >>

Int J Stem Cells (International journal of stem cells)
[2019, 12(1):139-150]

Cited: 4 times

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The Arthroscopic Loop Tenodesis Procedure: An Implant-Free Technique to Treat Long Biceps Tendon Pathologies.

Maximilian Kerschbaum, Isabella Weiss, Agnes Mayr, Christian Pfeifer, Michael Nerlich, Stefan Greiner,

Different surgical techniques are available to treat pathologies of the long biceps tendon. Although simple tenotomy of the tendon can result in distalization of the biceps muscle, implant-associated complications can occur after bony tendon fixation within a biceps tenodesis. This article describes the arthroscopic loop tenodesis procedure. The technique is ... Read more >>

Arthrosc Tech (Arthroscopy techniques)
[2019, 8(5):e503-e506]

Cited: 3 times

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Tenomodulin regulates matrix remodeling of mouse tendon stem/progenitor cells in an ex vivo collagen I gel model.

Heyong Yin, Manuel Delgado Caceres, Zexing Yan, Matthias Schieker, Michael Nerlich, Denitsa Docheva,

Tenomodulin (Tnmd) is predominantly expressed in tendon and ligament tissues. Loss of Tnmd in mice leads to a profound phenotype in vitro, characterized by reduced self-renewal but increased senescence of mouse tendon stem/progenitor cells (mTSPCs), as well as in vivo, by significantly impaired early tendon healing. Interestingly, injuried Achilles tendons from Tnmd-deficient ... Read more >>

Biochem Biophys Res Commun (Biochemical and biophysical research communications)
[2019, 512(4):691-697]

Cited: 6 times

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Early functional rehabilitation after patellar dislocation-What procedures are daily routine in orthopedic surgery?

Franz Hilber, Christian Pfeifer, Clemens Memmel, Johannes Zellner, Peter Angele, Michael Nerlich, Maximilian Kerschbaum, Daniel Popp, Florian Baumann, Werner Krutsch,

INTRODUCTION:Patellar dislocation and rupture of the medial patellofemoral ligament (MPFL) are frequently seen in daily orthopedic practice. Besides initial non-surgical treatment, surgery and subsequent rehabilitation are crucial for restoring stability in the femoropatellar joint. This study investigated current rehabilitation strategies after patellar dislocation because knowledge on this topic has been ... Read more >>

Injury (Injury)
[2019, 50(3):752-757]

Cited: 1 time

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Contact times of change-of-direction manoeuvres are influenced by age and the type of sports: a novel protocol using the SpeedCourt® system.

Leonard Achenbach, Werner Krutsch, Matthias Koch, Florian Zeman, Michael Nerlich, Peter Angele,

<h4>Purpose</h4>Side-to-side asymmetry in side-cutting manoeuvres is a known risk factor for severe knee injury. Potential leg asymmetry during ground contact times of different change-of-direction manoeuvres was evaluated in athletes by means of the recently developed SpeedCourt<sup>®</sup> system. The hypotheses were that ground contact times and the limb symmetry index are ... Read more >>

Knee Surg Sports Traumatol Arthrosc (Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA)
[2019, 27(3):991-999]

Cited: 0 times

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Injury incidence in semi-professional football claims for increased need of injury prevention in elite junior football.

Oliver Loose, Birgit Fellner, Jennifer Lehmann, Leonard Achenbach, Volker Krutsch, Stephan Gerling, Petra Jansen, Peter Angele, Michael Nerlich, Werner Krutsch,

<h4>Purpose</h4>Injuries are a common occurrence in football. Sufficient epidemiological data are available in professional football but not in salaried semi-professional football. This study investigates the injury incidence at different levels of semi-professional football with focus on junior football.<h4>Methods</h4>The data were based on injury reports provided by players and medical staff ... Read more >>

Knee Surg Sports Traumatol Arthrosc (Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA)
[2019, 27(3):978-984]

Cited: 3 times

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Kooperation der DGOU mit der ORS.

Susanne Grässel, Joachim Windolf, Werner E Siebert, Michael Nerlich, Markus Loibl,

Z Orthop Unfall (Zeitschrift fur Orthopadie und Unfallchirurgie)
[2018, 156(5):493-495]

Cited: 0 times

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Partial Anterior Cruciate Ligament Ruptures: Advantages by Intraligament Autologous Conditioned Plasma Injection and Healing Response Technique-Midterm Outcome Evaluation.

Matthias Koch, Felix Mayr, Leonard Achenbach, Werner Krutsch, Siegmund Lang, Franz Hilber, Johannes Weber, Christian G Pfeifer, Rebecca Woehl, Jürgen Eichhorn, Johannes Zellner, Michael Nerlich, Peter Angele,

The historical treatment options for partial anterior cruciate ligament (ACL) ruptures were conservative therapy or ACL reconstruction by injured bundle or entire ACL replacement. In awareness of the regenerative potential of biologic agents such as mesenchymal stem cells or platelet rich plasma (PRP), the healing response technique was developed to ... Read more >>

Biomed Res Int (BioMed research international)
[2018, 2018:3204869]

Cited: 3 times

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Clinical application of a minimally invasive cement-augmentable Schanz screw rod system to treat pelvic ring fractures.

Paul Schmitz, Florian Baumann, Yves P Acklin, Boyko Gueorguiev, Michael Nerlich, Stephan Grechenig, Michael Bernd Müller,

<h4>Purpose</h4>The purpose of this study is to analyze the results using the USS fracture MIS system (DePuy Synthes) to treat instable pelvic ring fractures. As its outstanding feature, it is the only Schanz screw and rod system at present that combines angular stability, perforation/fenestration of the screws for cement-augmentation, a ... Read more >>

Int Orthop (International orthopaedics)
[2019, 43(3):697-703]

Cited: 4 times

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Injury prevention and return to play strategies in elite football: no consent between players and team coaches.

Oliver Loose, Leonard Achenbach, Birgit Fellner, Jennifer Lehmann, Petra Jansen, Michael Nerlich, Peter Angele, Werner Krutsch,

<h4>Introduction</h4>Injuries are a common problem in football. To improve prevention strategies, the players' (p) and coaches' (c) views need to be disclosed as they have a strong impact on return to play decisions. The aim of this study is to reveal current opinions with regard to injury prevention and return ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2018, 138(7):985-992]

Cited: 8 times

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A guideline for placement of an infra-acetabular screw based on anatomic landmarks via an intra-pelvic approach.

Florian Baumann, Paul Schmitz, Daniel Mahr, Maximilian Kerschbaum, Axel Gänsslen, Michael Nerlich, Michael Worlicek,

<h4>Background</h4>Due to demographic changes, more and more fracture patterns involving anterior acetabular structures occur. The infra-acetabular screw is seen a useful tool to increase stability in fixation of the acetabular cup. However, the exact position of this screw in relation to anatomic landmarks which are intra-operatively palpable via an intra-pelvic ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2018, 13(1):77]

Cited: 6 times

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Patient-related quality of life after pelvic ring fractures in elderly.

Paul Schmitz, Stephan Lüdeck, Florian Baumann, Rainer Kretschmer, Michael Nerlich, Maximilian Kerschbaum,

<h4>Purpose</h4>Pelvic ring fractures, occurring in elderly patients are a challenging problem. Little known is about the patient-related outcome after these injuries. The primary objective of this study is to evaluate the quality of life after pelvic ring injuries in patients aged over 60 years.<h4>Methods</h4>Patients (≥ 60 years) with pelvic ring fractures treated in ... Read more >>

Int Orthop (International orthopaedics)
[2019, 43(2):261-267]

Cited: 10 times

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11.361 sports injuries in a 15-year survey of a Level I emergency trauma department reveal different severe injury types in the 6 most common team sports.

Werner Krutsch, Volker Krutsch, Franz Hilber, Christian Pfeifer, Florian Baumann, Johannes Weber, Paul Schmitz, Maximilian Kerschbaum, Michael Nerlich, Peter Angele,

<h4>Introduction</h4>Severe sports-related injuries are a common affliction treated in Level I trauma departments. Detailed knowledge on injury characteristics from different medical settings is essential to improve the development of injury prevention strategies in different team sports.<h4>Methods</h4>Team sport injuries were retrospectively analysed in a Level I trauma department registry over 15 ... Read more >>

Sportverletz Sportschaden (Sportverletzung Sportschaden : Organ der Gesellschaft fur Orthopadisch-Traumatologische Sportmedizin)
[2018, 32(2):111-119]

Cited: 4 times

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Correction to: Intra-ligamentary autologous conditioned plasma and healing response to treat partial ACL ruptures.

Matthias Koch, Berardo Di Matteo, Jürgen Eichhorn, Johannes Zellner, Felix Mayr, Werner Krutsch, Leonard Achenbach, Rebecca Woehl, Michael Nerlich, Peter Angele,

With regards to Berardo Di Matteo, second author. The author's name is incorrectly listed on Pub-Med. The first and last name have been mixed up. ... Read more >>

Arch Orthop Trauma Surg (Archives of orthopaedic and trauma surgery)
[2018, 138(5):685]

Cited: 0 times

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Biomechanical analysis of iliac crest loading following cortico-cancellous bone harvesting.

Paul Schmitz, Christoph Cornelius Neumann, Carsten Neumann, Michael Nerlich, Sebastian Dendorfer,

<h4>Background</h4>Iliac crest bone harvesting is a frequently performed surgical procedure widely used to treat bone defects. The objective of this study is to assess the biomechanical quantities related to risk for pelvic fracture after harvesting an autologous bone graft at the anterior iliac crest.<h4>Methods</h4>Finite element models with a simulated harvest ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2018, 13(1):108]

Cited: 0 times

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