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Author Mi Sun Kim

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Inhibition of SARS-CoV 3CL protease by flavonoids.

Seri Jo, Suwon Kim, Dong Hae Shin, Mi-Sun Kim,

There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required. Coronaviruses (CoVs) have been rising targets of some flavonoids. The antiviral activity of some flavonoids against CoVs is presumed directly caused by inhibiting 3C-like protease (3CLpro). Here, ... Read more >>

J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2020, 35(1):145-151]

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Parkinson Disease-Related Pattern of Glucose Metabolism Associated With the Potential for Motor Improvement After Deep Brain Stimulation.

Eun Jung Lee, Jungsu S Oh, Hyojeong Moon, Min-Ju Kim, Mi Sun Kim, Sun Ju Chung, Jae Seung Kim, Sang Ryong Jeon,

BACKGROUND:Motor dysfunctions in Parkinson disease (PD) patients are not completely normalized by deep brain stimulation (DBS), and there is an obvious difference in the degree of symptom improvement after DBS for each patient. OBJECTIVE:To test our hypothesis that each patient has their own restoration capacity for motor improvement after DBS, ... Read more >>

Neurosurgery (Neurosurgery)
[2020, 86(4):492-499]

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Re-Irradiation and Its Contribution to Good Prognosis in Recurrent Glioblastoma Patients.

Mi Sun Kim, Jaejoon Lim, Hyun Soo Shin, Kyung Gi Cho,

BACKGROUND:Radiation therapy, one of the strongest anti-cancer treatments, is already performed to treat primary glioblastoma; however, the effect of repeated radiation therapy for recurrent tumors has not been fully explored. The aim of this study was to determine the efficacy of re-irradiation in treating recurrent glioblastoma. METHODS:The study included 36 ... Read more >>

Brain Tumor Res Treat (Brain tumor research and treatment)
[2020, 8(1):29-35]

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Age-dependent facial subcutaneous fat thickness by high-frequency medical diagnostic ultrasound system.

Mi-Sun Kim, Yong Yeon Jeong, Sun Gyoo Park, Nae-Gyu Kang,

Skin Res Technol (Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI))
[2020, :]

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Assessing the Presence of Post-Traumatic Stress and Turnover Intention Among Nurses Post-Middle East Respiratory Syndrome Outbreak: The Importance of Supervisor Support.

Heeja Jung, Sun Young Jung, Mi Hyang Lee, Mi Sun Kim,

Background: South Korea faced the Middle East Respiratory Syndrome (MERS) outbreak for the first time in 2015, which resulted in 186 infected patients and 39 deaths. This study investigated the level of post-traumatic stress disorder (PTSD) and turnover intention, the relationship between PTSD and turnover intention, and the buffering effect ... Read more >>

Workplace Health Saf (Workplace health & safety)
[2020, :2165079919897693]

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The Use of Histidine-tryptophan-ketoglutarate Solution as a New Storage Medium for the Avulsed Tooth.

Tae Jun Oh, Ok Hyung Nam, Mi Sun Kim, Hyo-Seol Lee, Yu-Shik Hwang, Sung Chul Choi,

INTRODUCTION:Histidine-tryptophan-ketoglutarate (HTK) is a preservation solution used for organ transplantation. The physiological pH and osmolality of this solution are known to facilitate cell proliferation and cell membrane stabilization. The purpose of the present study was to investigate the efficacy of several concentrations of HTK solution as a storage medium for ... Read more >>

J Endod (Journal of endodontics)
[2020, 46(1):74-80]

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GTP Preference of d-Glycero-α-d-manno-Heptose-1-Phosphate Guanylyltransferase from Yersinia pseudotuberculosis.

Suwon Kim, Mi-Sun Kim, Seri Jo, Dong Hae Shin,

d-glycero-α-d-manno-heptose-1-phosphate guanylyltransferase (HddC) is the fourth enzyme synthesizing a building component of lipopolysaccharide (LPS) of Gram-negative bacteria. Since HddC is a potential new target to develop antibiotics, the analysis of the structural and functional relationship of the complex structure will lead to a better idea to design inhibitory compounds. X-ray ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 21(1):]

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Factors influencing self-management in Parkinson's disease: A cross-sectional study.

Kyeung Eun Lim, Sung Reul Kim, Young Hee Sung, Sun-Young Oh, Mi Sun Kim, Sun Ju Chung,

This study aimed to identify factors influencing self-management in patients with Parkinson's disease (PD) based on social cognitive theory. A cross-sectional design was used; data were collected at three tertiary medical centers in Korea from a convenience sample of 356 PD patients. Higher self-management scores were associated with higher education ... Read more >>

Geriatr Nurs (Geriatric nursing (New York, N.Y.))
[2019, :]

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A Study of a Potent Inhibitor Against a GDP-6-Deoxy-α-d-Manno-Heptose Biosynthesis Pathway as Antibiotic Candidates.

Suwon Kim, Seri Jo, Mi-Sun Kim, Dong Hae Shin,

The GDP-6-deoxy-α-d-manno-heptose is a key building block molecule in constructing lipopolysaccharide of Gram-negative bacteria. Therefore, blockage of the biosynthesis pathway of GDP-6-deoxy-α-d-manno-heptose is lethal or increases antibiotics susceptibility to pathogens. In this study, we assayed d-glycero-α-d-manno-heptose-1-phosphate guanylyltransferase (HddC) from Yersinia pseudotuberculosis (Yp) using an efficient assay method supplying its natural ... Read more >>

Microb. Drug Resist. (Microbial drug resistance (Larchmont, N.Y.))
[2020, 26(4):385-390]

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In vivo evaluation of scaffolds compatible for colonoid engraftments onto injured mouse colon epithelium.

JooHyun Jee, Sang Yun Jeong, Han Kyung Kim, Seon Young Choi, Sukin Jeong, Joongwoon Lee, Ji Su Ko, Mi Sun Kim, Min-Soo Kwon, Jongman Yoo,

Colon organoids (colonoids) are known to be similar to colon tissue in structure and function, which makes them useful in the treatment of intestinal de-epithelialized disease. Matrigel, which is used as a transplantation scaffold for colonoids, cannot be used in clinical applications because of its undefined composition and tumorigenicity. This ... Read more >>

FASEB J. (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2019, 33(9):10116-10125]

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Indoleamine-2,3-Dioxygenase in Thyroid Cancer Cells Suppresses Natural Killer Cell Function by Inhibiting NKG2D and NKp46 Expression via STAT Signaling Pathways.

Arum Park, Yunjeong Yang, Yunhee Lee, Mi Sun Kim, Young-Jun Park, Haiyoung Jung, Tae-Don Kim, Hee Gu Lee, Inpyo Choi, Suk Ran Yoon,

Natural killer (NK) cells are key players in the immune system. They use receptors on their cell surface to identify target cells. However, to escape being killed by the immune system, cancer cells such as thyroid cancer cells, use various methods to suppress the function of NK cells. Thus, this ... Read more >>

J Clin Med (Journal of clinical medicine)
[2019, 8(6):]

Cited: 1 time

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Evaluation of the periodontal and pulpal healing of replanted rat molars with doxycycline root conditioning.

Ok Hyung Nam, Kyounga Cheon, Mi Sun Kim, Hyo-Seol Lee, Sung Chul Choi,

Purpose:This study aimed to evaluate periodontal and pulpal healing in replanted rat teeth, preserved under different storage conditions, with or without root conditioning using doxycycline. Methods:A total of 40 maxillary first molars extracted from 20 Sprague-Dawley rats were stored for different durations under different conditions (5 minutes in dry storage ... Read more >>

J Periodontal Implant Sci (Journal of periodontal & implant science)
[2019, 49(3):148-157]

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Massive Broad Ligament Hematoma Caused by Spontaneous Uterine Artery Rupture after Uncomplicated Vaginal Delivery.

Hyun Jung Lee, Eun Duc Na, Hyeon Chul Kim, Mi Sun Kim, Myoung Jin Moon,

J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2020, 27(2):250-253]

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Obstetrical Outcomes of Amniocentesis or Chorionic Villus Sampling in Dichorionic Twin Pregnancies.

Mi Sun Kim, Myoung Jin Moon, Sukho Kang, Sang Hee Jung, Sung Woon Chang, Hyo Jin Ki, Bohye Kim, Eunhee Ahn,

BACKGROUND:Under certain situations, women with twin pregnancies may be counseled to undergo invasive prenatal diagnostic testing. Chorionic villus sampling and amniocentesis are the two generally performed invasive prenatal diagnostic tests. Studies comparing procedure-related fetal loss between first-trimester chorionic villus sampling and second-trimester amniocentesis in twin pregnancies are limited. This study ... Read more >>

J. Korean Med. Sci. (Journal of Korean medical science)
[2019, 34(18):e142]

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Pupillary dysfunction of multiple system atrophy: Dynamic pupillometric findings and clinical correlations.

Kye Won Park, Nari Choi, Ho-Sung Ryu, Mi Sun Kim, Eun-Jae Lee, Sun Ju Chung,

INTRODUCTION:Although autonomic dysfunction is the prominent clinical feature in multiple system atrophy (MSA), little is known about the pupillary autonomic aspect of MSA. We aimed to evaluate pupillary autonomic function in MSA patients using dynamic pupillometry, which can quantify the pupillary light reflex. METHODS:Dynamic pupillometry parameters were compared in 21 ... Read more >>

Parkinsonism Relat. Disord. (Parkinsonism & related disorders)
[2019, 65:234-237]

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Real-Life Clinical Use of Symbicort® Maintenance and Reliever Therapy for Asthmatic Patients in Korea.

Sang Hoon Kim, Tae Bum Kim, Sang Heon Kim, Heung Woo Park, Sook Hee Song, Jae Won Jeong, Young Koo Jee, Sang Won Park, Mi Sun Kim, Ho Joo Yoon,

The aim of this study was to examine the daily practice patterns of Symbicort® Maintenance and Reliever Therapy (SMART) in Korean asthmatic patients and to analyze clinical signs related to overuse. This study used an observational, multicenter, noninterventional, prospective, uncontrolled design for examining asthmatic patients prescribed SMART to assess the ... Read more >>

Allergy Asthma Immunol Res (Allergy, asthma & immunology research)
[2018, 10(1):88-94]

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Obstetrical outcomes of embryo reduction and fetal reduction compared to non-reduced twin pregnancies.

Mi Sun Kim, Sukho Kang, Eun Duc Na, Jisun Im, Eunhee Ahn, Ji Eun Shin, Myoung Jin Moon,

PURPOSE:To prevent perinatal morbidity and mortality of high-order multiple pregnancy (HOMP), multifetal pregnancy reduction (MPR) is offered to some patients. In this study, we investigated whether twin pregnancies derived from MPRs carry a higher adverse obstetrical outcome compared to non-reduced control group of twins. METHODS:We retrospectively analyzed the data from ... Read more >>

Arch. Gynecol. Obstet. (Archives of gynecology and obstetrics)
[2019, 299(4):953-960]

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Three-dimensional motion capture data during repetitive overarm throwing practice.

Gizem Ozkaya, Hae Ryun Jung, In Sub Jeong, Min Ra Choi, Min Young Shin, Xue Lin, Woo Seong Heo, Mi Sun Kim, Eonho Kim, Ki-Kwang Lee,

Three-dimensional motion capture analysis is considered the gold standard for any movement research. Motion capture data were recorded for 7 healthy female participants with no prior throwing experience to investigate the learning process for overarm throwing during a selected period. Participants were monitored 3 times a week for 5 weeks. ... Read more >>

Sci Data (Scientific data)
[2018, 5:180272]

Cited: 1 time

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Leucine-rich repeat-containing G-protein coupled receptor 5 enriched organoids under chemically-defined growth conditions.

Soojung Hahn, Mi Sun Kim, Seon Young Choi, Sukin Jeong, JooHyun Jee, Han Kyung Kim, Sang Yun Jeong, Hyunsoo Shin, Hyoung Sun Kim, Joon Seong Park, Jongman Yoo,

An organoid is a complex, multi-cell three-dimensional (3D) structure that contains tissue-specific cells. Epithelial stem cells, which are marked by leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5), have the potential for self-renewal and expansion as organoids. However, in the case of intestinal organoids from Lgr5-EGFP-IRES-CreERT2 transgenic mice, in vitro expansion of ... Read more >>

Biochem. Biophys. Res. Commun. (Biochemical and biophysical research communications)
[2019, 508(2):430-439]

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Anti-melanogenic and anti-oxidant activities of ethanol extract of Kummerowia striata: Kummerowia striata regulate anti-melanogenic activity through down-regulation of TRP-1, TRP-2 and MITF expression.

Jae Yeon Lee, Young-Rak Cho, Ju Hyoung Park, Eun-Kyung Ahn, Wonsik Jeong, Hyoung Seok Shin, Mi-Sun Kim, Seung Hwan Yang, Joa Sub Oh,

Kummerowia striata (K. striata) is used as a traditional medicine for inflammation-related therapy. To determine whether it has beneficial anti-melanogenic and anti-oxidant activities, we investigated the biological activities of the ethanol extract of Kummerowia striata (EKS) using a variety of in vitro and cell culture model systems. The anti-melanogenic activity ... Read more >>

Toxicol Rep (Toxicology reports)
[2019, 6:10-17]

Cited: 2 times

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Transabdominal selective feticide in dichorionic twins: Ten years' experience at a single center.

Mi Sun Kim, Eun Duc Na, Sukho Kang, So Yeon Shin, Bo Bae Lim, Hounyoung Kim, Myoung Jin Moon,

AIM:The present study investigates the procedure-related fetal loss rate and obstetrical outcomes of selective feticide in dichorionic twins. METHODS:We retrospectively analyzed the data of 44 cases of dichorionic twins. Two different indications for selective feticide were set: (i) the presence of genetic or congenital anomaly; and (ii) an obstetrical indication ... Read more >>

J. Obstet. Gynaecol. Res. (The journal of obstetrics and gynaecology research)
[2019, 45(2):299-305]

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Thermal characteristics of non-biological vessel phantoms for treatment of varicose veins using high-intensity focused ultrasound.

Mi-Sun Kim, Ju-Young Kim, Si-Cheol Noh, Heung-Ho Choi,

The ultrasonic treatment of varicose veins uses high-intensity focused ultrasound, in which a blood vessel is contracted by converting acoustic energy into thermal energy. In this study, we propose a phantom of varicose veins that can be applied for the efficient evaluation of ultrasonic treatment in varicose veins. The proposed ... Read more >>

PLoS ONE (PloS one)
[2017, 12(4):e0174922]

Cited: 1 time

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Prostaglandin E2 Secreted by Thyroid Cancer Cells Contributes to Immune Escape Through the Suppression of Natural Killer (NK) Cell Cytotoxicity and NK Cell Differentiation.

Arum Park, Yunhee Lee, Mi Sun Kim, Young Ju Kang, Young-Jun Park, Haiyoung Jung, Tae-Don Kim, Hee Gu Lee, Inpyo Choi, Suk Ran Yoon,

Natural killer (NK) cells play important roles in immune surveillance. However, the tumor microenvironment suppresses NK cell function and allows cancer cells to evade immune detection. In this study, we investigated whether the thyroid cancer cell microenvironment has this effect on NK cells. We found that prostaglandin (PG) E2 produced ... Read more >>

Front Immunol (Frontiers in immunology)
[2018, 9:1859]

Cited: 8 times

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Radiation safety education and compliance with safety procedures-The Korea Nurses' Health Study.

Oksoo Kim, Mi Sun Kim, Hee Jung Jang, Hyangkyu Lee, Younhee Kang, Yanghee Pang, Heeja Jung,

AIMS AND OBJECTIVES:To examine the current state of radiation safety education and its influence on nurses' compliance with safety procedures. BACKGROUND:Use of radiation in therapy and diagnosis has prolonged and improved millions of lives, but it presents potential hazards for healthcare professionals. DESIGN:A cross-sectional design. METHODS:Participants included 1,672 female nurses ... Read more >>

J Clin Nurs (Journal of clinical nursing)
[2018, 27(13-14):2650-2660]

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Anti-melanogenic and Anti-oxidant Activities of an Ethanolic Extract of Kummerowia striata and its active compounds, p-coumaric acid and quercetin

Ju-Hyoung Park, Jae Yeon Lee, Young-Rak Cho, Eun-Kyung Ahn, Wonsik Jeong, Hyoung Seok Shin, Mi-Sun Kim, Joa Sub Oh,

Kummerowia striata is a traditional medicine used for the therapy of inflammation-related diseases. Herein, we investigated the anti-melanogenic and antioxidant activities of an ethanolic extract of K. striata (EKS) using a number of in vitro and cell culture model systems. The anti-melanogenic effect was assessed in B16F10 melanoma cells based ... Read more >>

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