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New insights into atypical Alzheimer's disease in the era of biomarkers.

Jonathan Graff-Radford, Keir X X Yong, Liana G Apostolova, Femke H Bouwman, Maria Carrillo, Bradford C Dickerson, Gil D Rabinovici, Jonathan M Schott, David T Jones, Melissa E Murray,

Most patients with Alzheimer's disease present with amnestic problems; however, a substantial proportion, over-represented in young-onset cases, have atypical phenotypes including predominant visual, language, executive, behavioural, or motor dysfunction. In the past, these individuals often received a late diagnosis; however, availability of CSF and PET biomarkers of Alzheimer's disease pathologies ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2021, 20(3):222-234]

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TAR DNA-Binding Protein 43 Is Associated with Rate of Memory and Functional and Global Cognitive Decline in the Decade Prior to Death.

Marina Buciuc, Nirubol Tosakulwong, Mary M Machulda, Jennifer L Whitwell, Stephen D Weigand, Melissa E Murray, R Ross Reichard, Joseph E Parisi, Dennis W Dickson, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs,

<h4>Background</h4>Transactive response DNA-binding protein of 43 kDa (TDP-43) is associated with memory impairment and overall cognitive decline. It is unclear how TDP-43 contributes to the rate of clinical decline.<h4>Objective</h4>To determine whether cross-sectional and longitudinal cognitive and functional decline are associated with anatomical distribution of TDP-43 in the brain.<h4>Methods</h4>Longitudinal clinical-neuropathologic autopsy cohort ... Read more >>

J Alzheimers Dis (Journal of Alzheimer's disease : JAD)
[2021, :]

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The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer's disease.

Billie J Matchett, Lea T Grinberg, Panos Theofilas, Melissa E Murray,

Alzheimer's disease (AD) is neuropathologically characterized by the intracellular accumulation of hyperphosphorylated tau and the extracellular deposition of amyloid-β plaques, which affect certain brain regions in a progressive manner. The locus coeruleus (LC), a small nucleus in the pons of the brainstem, is widely recognized as one of the earliest ... Read more >>

Acta Neuropathol (Acta neuropathologica)
[2021, :]

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Protein contributions to brain atrophy acceleration in Alzheimer's disease and primary age-related tauopathy.

Keith A Josephs, Peter R Martin, Stephen D Weigand, Nirubol Tosakulwong, Marina Buciuc, Melissa E Murray, Leonard Petrucelli, Matthew L Senjem, Anthony J Spychalla, David S Knopman, Bradley F Boeve, Ronald C Petersen, Joseph E Parisi, Dennis W Dickson, Clifford R Jack, Jennifer L Whitwell,

Alzheimer's disease is characterized by the presence of amyloid-β and tau deposition in the brain, hippocampal atrophy and increased rates of hippocampal atrophy over time. Another protein, TAR DNA binding protein 43 (TDP-43) has been identified in up to 75% of cases of Alzheimer's disease. TDP-43, tau and amyloid-β have ... Read more >>

Brain (Brain : a journal of neurology)
[2020, 143(11):3463-3476]

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MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features.

Rebecca R Valentino, Shunsuke Koga, Ronald L Walton, Alexandra I Soto-Beasley, Naomi Kouri, Michael A DeTure, Melissa E Murray, Patrick W Johnson, Ronald C Petersen, Bradley F Boeve, Ryan J Uitti, Zbigniew K Wszolek, Dennis W Dickson, Owen A Ross, Michael G Heckman,

The microtubule-associated protein tau (MAPT) H1 haplotype is the strongest genetic risk factor for corticobasal degeneration (CBD). However, the specific H1 subhaplotype association is not well defined, and it is not clear whether any MAPT haplotypes influence severity of tau pathology or clinical presentation in CBD. Therefore, in the current ... Read more >>

Acta Neuropathol Commun (Acta neuropathologica communications)
[2020, 8(1):218]

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Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology.

Xu Hou, Jens O Watzlawik, Casey Cook, Chia-Chen Liu, Silvia S Kang, Wen-Lang Lin, Michael DeTure, Michael G Heckman, Nancy N Diehl, Fadi S Hanna Al-Shaikh, Ronald L Walton, Owen A Ross, Heather L Melrose, Nilüfer Ertekin-Taner, Guojun Bu, Leonard Petrucelli, John D Fryer, Melissa E Murray, Dennis W Dickson, Fabienne C Fiesel, Wolfdieter Springer,

<h4>Introduction</h4>The cytoprotective PTEN-induced kinase 1 (PINK1)-parkin RBR E3 ubiquitin protein ligase (PRKN) pathway selectively labels damaged mitochondria with phosphorylated ubiquitin (pS65-Ub) for their autophagic removal (mitophagy). Because dysfunctions of mitochondria and degradation pathways are early features of Alzheimer's disease (AD), mitophagy impairments may contribute to the pathogenesis.<h4>Methods</h4>Morphology, levels, and distribution ... Read more >>

Alzheimers Dement (Alzheimer's & dementia : the journal of the Alzheimer's Association)
[2020, :]

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Association of ABI3 and PLCG2 missense variants with disease risk and neuropathology in Lewy body disease and progressive supranuclear palsy.

Samantha L Strickland, Hélène Morel, Christian Prusinski, Mariet Allen, Tulsi A Patel, Minerva M Carrasquillo, Olivia J Conway, Sarah J Lincoln, Joseph S Reddy, Thuy Nguyen, Kimberly G Malphrus, Alexandra I Soto, Ronald L Walton, Julia E Crook, Melissa E Murray, Bradley F Boeve, Ronald C Petersen, John A Lucas, Tanis J Ferman, Ryan J Uitti, Zbigniew K Wszolek, Owen A Ross, Neill R Graff-Radford, Dennis W Dickson, Nilüfer Ertekin-Taner,

Missense variants ABI3_rs616338-T and PLCG2_rs72824905-G were previously associated with elevated or reduced risk of Alzheimer's disease (AD), respectively. Despite reports of associations with other neurodegenerative diseases, there are few studies of these variants in purely neuropathologically diagnosed cohorts. Further, the effect of these mutations on neurodegenerative disease pathologies is unknown. ... Read more >>

Acta Neuropathol Commun (Acta neuropathologica communications)
[2020, 8(1):172]

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Sensitivity-Specificity of Tau and Amyloid β Positron Emission Tomography in Frontotemporal Lobar Degeneration.

Alma Ghirelli, Nirubol Tosakulwong, Stephen D Weigand, Heather M Clark, Farwa Ali, Hugo Botha, Joseph R Duffy, Rene L Utianski, Marina Buciuc, Melissa E Murray, Sydney A Labuzan, Anthony J Spychalla, Nha Trang Thu Pham, Christopher G Schwarz, Matthew L Senjem, Mary M Machulda, Matthew Baker, Rosa Rademakers, Massimo Filippi, Clifford R Jack, Val J Lowe, Joseph E Parisi, Dennis W Dickson, Keith A Josephs, Jennifer L Whitwell,

<h4>Objective</h4>To examine associations between tau and amyloid β (Aβ) molecular positron emission tomography (PET) and both Alzheimer-related pathology and 4-repeat tau pathology in autopsy-confirmed frontotemporal lobar degeneration (FTLD).<h4>Methods</h4>Twenty-four patients had [<sup>18</sup> F]-flortaucipir-PET and died with FTLD (progressive supranuclear palsy [PSP], n = 10; corticobasal degeneration [CBD], n = 10; FTLD-TDP, ... Read more >>

Ann Neurol (Annals of neurology)
[2020, 88(5):1009-1022]

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Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease.

Chia-Chen Liu, Yu Yamazaki, Michael G Heckman, Yuka A Martens, Lin Jia, Akari Yamazaki, Nancy N Diehl, Jing Zhao, Na Zhao, Michael DeTure, Mary D Davis, Lindsey M Felton, Wenhui Qiao, Yonghe Li, Hongmei Li, Yuan Fu, Na Wang, Melissa Wren, Tomonori Aikawa, Marie-Louise Holm, Hiroshi Oue, Cynthia Linares, Mariet Allen, Minerva M Carrasquillo, Melissa E Murray, Ronald C Petersen, Nilüfer Ertekin-Taner, Dennis W Dickson, Takahisa Kanekiyo, Guojun Bu,

<h4>Introduction</h4>Cerebrovascular pathologies including cerebral amyloid angiopathy (CAA) and blood-brain barrier (BBB) dysregulation are prominent features in the majority of Alzheimer's disease (AD) cases.<h4>Methods</h4>We performed neuropathologic and biochemical studies on a large, neuropathologically confirmed human AD cohort (N = 469). Amounts of endothelial tight junction proteins claudin-5 (CLDN5) and occludin (OCLN), ... Read more >>

Alzheimers Dement (Alzheimer's & dementia : the journal of the Alzheimer's Association)
[2020, 16(10):1372-1383]

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Subtypes of dementia with Lewy bodies are associated with α-synuclein and tau distribution.

Tanis J Ferman, Naoya Aoki, Bradley F Boeve, Jeremiah A Aakre, Kejal Kantarci, Jonathan Graff-Radford, Joseph E Parisi, Jay A Van Gerpen, Neill R Graff-Radford, Ryan J Uitti, Otto Pedraza, Melissa E Murray, Zbigniew K Wszolek, R Ross Reichard, Julie A Fields, Owen A Ross, David S Knopman, Ronald C Petersen, Dennis W Dickson,

<h4>Objective</h4>To determine whether Lewy body disease subgroups have different clinical profiles.<h4>Methods</h4>Participants had dementia, autopsy-confirmed transitional or diffuse Lewy body disease (TLBD or DLBD) (n = 244), or Alzheimer disease (AD) (n = 210), and were seen at least twice (mean follow-up 6.2 ± 3.8 years). TLBD and DLBD groups were ... Read more >>

Neurology (Neurology)
[2020, 95(2):e155-e165]

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Clinical and pathologic features of cognitive-predominant corticobasal degeneration.

Nobutaka Sakae, Octavio A Santos, Otto Pedraza, Irene Litvan, Melissa E Murray, Ranjan Duara, Ryan J Uitti, Zbigniew K Wszolek, Neill R Graff-Radford, Keith A Josephs, Dennis W Dickson,

<h4>Objective</h4>To describe clinical and pathologic characteristics of corticobasal degeneration (CBD) with cognitive predominant problems during the disease course.<h4>Methods</h4>In a series of autopsy-confirmed cases of CBD, we identified patients with cognitive rather than motor predominant features (CBD-Cog), including 5 patients thought to have Alzheimer disease (AD) and 10 patients thought to ... Read more >>

Neurology (Neurology)
[2020, 95(1):e35-e45]

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Utility of FDG-PET in diagnosis of Alzheimer-related TDP-43 proteinopathy.

Marina Buciuc, Hugo Botha, Melissa E Murray, Christopher G Schwarz, Matthew L Senjem, David T Jones, David S Knopman, Bradley F Boeve, Ronald C Petersen, Clifford R Jack, Leonard Petrucelli, Joseph E Parisi, Dennis W Dickson, Val Lowe, Jennifer L Whitwell, Keith A Josephs,

<h4>Objective</h4>To evaluate FDG-PET as an antemortem diagnostic tool for Alzheimer-related TAR DNA-binding protein of 43 kDa (TDP-43) proteinopathy.<h4>Methods</h4>We conducted a cross-sectional neuroimaging-histologic analysis of patients with antemortem FDG-PET and postmortem brain tissue from the Mayo Clinic Alzheimer's Disease Research Center and Study of Aging with Alzheimer spectrum pathology. TDP-43-positive status ... Read more >>

Neurology (Neurology)
[2020, 95(1):e23-e34]

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Pick's disease: clinicopathologic characterization of 21 cases.

Parichita Choudhury, Eugene L Scharf, Michael A Paolini, Jonathan Graff-Radford, Eva C Alden, Mary M Machulda, David T Jones, Julie A Fields, Melissa E Murray, Neill R Graff-Radford, Eleni Constantopoulos, Ross R Reichard, David S Knopman, Joseph R Duffy, Dennis W Dickson, Joseph E Parisi, Keith A Josephs, Ronald C Petersen, Bradley F Boeve,

BACKGROUND:Pick's disease (PiD) is a unique subtype of frontotemporal lobar degeneration characterized pathologically by aggregates of 3-Repeat tau. Few studies have examined the clinical variability and disease progression in PiD. We describe the clinical features, neuropsychological profiles and coexistent pathologies in 21 cases of autopsy-confirmed PiD. METHODS:This study was a ... Read more >>

J Neurol (Journal of neurology)
[2020, 267(9):2697-2704]

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Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies.

Xiaolai Zhou, Alexandra M Nicholson, Yingxue Ren, Mieu Brooks, Peizhou Jiang, Aamir Zuberi, Hung Nguyen Phuoc, Ralph B Perkerson, Billie Matchett, Tammee M Parsons, NiCole A Finch, Wenlang Lin, Wenhui Qiao, Monica Castanedes-Casey, Virginia Phillips, Ariston L Librero, Yan Asmann, Guojun Bu, Melissa E Murray, Cathleen Lutz, Dennis W Dickson, Rosa Rademakers,

Genetic variants that define two distinct haplotypes at the TMEM106B locus have been implicated in multiple neurodegenerative diseases and in healthy brain ageing. In frontotemporal dementia (FTD), the high expressing TMEM106B risk haplotype was shown to increase susceptibility for FTD with TDP-43 inclusions (FTD-TDP) and to modify disease penetrance in ... Read more >>

Brain (Brain : a journal of neurology)
[2020, 143(6):1905-1919]

Cited: 5 times

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Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes.

Ryan A Townley, Jonathan Graff-Radford, William G Mantyh, Hugo Botha, Angelina J Polsinelli, Scott A Przybelski, Mary M Machulda, Ahmed T Makhlouf, Matthew L Senjem, Melissa E Murray, Ross R Reichard, Rodolfo Savica, Bradley F Boeve, Daniel A Drubach, Keith A Josephs, David S Knopman, Val J Lowe, Clifford R Jack, Ronald C Petersen, David T Jones,

We report a group of patients presenting with a progressive dementia syndrome characterized by predominant dysfunction in core executive functions, relatively young age of onset and positive biomarkers for Alzheimer's pathophysiology. Atypical frontal, dysexecutive/behavioural variants and early-onset variants of Alzheimer's disease have been previously reported, but no diagnostic criteria exist ... Read more >>

Brain Commun (Brain communications)
[2020, 2(1):fcaa068]

Cited: 3 times

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Association between transactive response DNA-binding protein of 43 kDa type and cognitive resilience to Alzheimer's disease: a case-control study.

Marina Buciuc, Jennifer L Whitwell, Nirubol Tosakulwong, Stephen D Weigand, Melissa E Murray, Bradley F Boeve, David S Knopman, Joseph E Parisi, Ronald C Petersen, Dennis W Dickson, Keith A Josephs,

Association between the transactive response DNA-binding protein of 43 kDa (TDP-43), its newly described types (type α/type β), and resilience to Alzheimer's disease neuropathological change (ADNC) defined as preservation of normal cognitive functioning despite advanced ADNC has been evaluated in this case-control study of 63 older adults. Twenty-one resilient to ... Read more >>

Neurobiol Aging (Neurobiology of aging)
[2020, 92:92-97]

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Confirmation of 123I-FP-CIT SPECT Quantification Methods in Dementia with Lewy Bodies and Other Neurodegenerative Disorders.

Daniela D Maltais, Lennon G Jordan, Hoon-Ki Min, Toji Miyagawa, Scott A Przybelski, Timothy G Lesnick, Robert R Reichard, Dennis W Dickson, Melissa E Murray, Kejal Kantarci, Bradley F Boeve, Val J Lowe,

Our rationale was to conduct a retrospective study comparing 3 <sup>123</sup>I-<i>N</i>-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane (<sup>123</sup>I-FP-CIT) SPECT quantitative methods in patients with neurodegenerative syndromes as referenced to neuropathologic findings. <b>Methods:</b> <sup>123</sup>I-FP-CIT-SPECT and neuropathologic findings among patients with neurodegenerative syndromes from the Mayo Alzheimer Disease Research Center and Mayo Clinic Study of Aging were examined. ... Read more >>

J Nucl Med (Journal of nuclear medicine : official publication, Society of Nuclear Medicine)
[2020, 61(11):1628-1635]

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18F-fluorodeoxyglucose positron emission tomography in dementia with Lewy bodies.

Jonathan Graff-Radford, Timothy G Lesnick, Rodolfo Savica, Qin Chen, Tanis J Ferman, Scott A Przybelski, David T Jones, Matthew L Senjem, Jeffrey L Gunter, Walter K Kremers, Clifford R Jack, Val J Lowe, Ronald C Petersen, David S Knopman, Bradley F Boeve, Melissa E Murray, Dennis W Dickson, Kejal Kantarci,

Among individuals with dementia with Lewy bodies, pathologic correlates of clinical course include the presence and extent of coexisting Alzheimer's pathology and the presence of transitional or diffuse Lewy body disease. The objectives of this study are to determine (i) whether <sup>18</sup>F-fluorodeoxyglucose PET signature patterns of dementia with Lewy bodies ... Read more >>

Brain Commun (Brain communications)
[2020, 2(1):fcaa040]

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TDP-43 is associated with a reduced likelihood of rendering a clinical diagnosis of dementia with Lewy bodies in autopsy-confirmed cases of transitional/diffuse Lewy body disease.

Marina Buciuc, Jennifer L Whitwell, Bradley F Boeve, Tanis J Ferman, Jonathan Graff-Radford, Rodolfo Savica, Kejal Kantarci, Julie A Fields, David S Knopman, Ronald C Petersen, Joseph E Parisi, Melissa E Murray, Dennis W Dickson, Keith A Josephs,

<h4>Background</h4>Trans-active response DNA-binding protein of 43 kDa (TDP-43) can be detected in up to 63% of autopsy-confirmed Lewy body disease (LBD) cases. It is unclear whether TDP-43 is associated with a decreased likelihood of a clinical diagnosis of probable dementia with Lewy bodies (pDLB) during life.<h4>Methods</h4>In an autopsy cohort of 395 ... Read more >>

J Neurol (Journal of neurology)
[2020, 267(5):1444-1453]

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Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease.

Fadi S Hanna Al-Shaikh, Ranjan Duara, Julia E Crook, Elizabeth R Lesser, Jolien Schaeverbeke, Kelly M Hinkle, Owen A Ross, Nilufer Ertekin-Taner, Otto Pedraza, Dennis W Dickson, Neill R Graff-Radford, Melissa E Murray,

<h4>Importance</h4>Corticolimbic patterns of neurofibrillary tangle (NFT) accumulation define neuropathologic subtypes of Alzheimer disease (AD), which underlie the clinical heterogeneity observed antemortem. The cholinergic system, which is the target of acetylcholinesterase inhibitor therapy, is selectively vulnerable in AD.<h4>Objective</h4>To investigate the major source of cholinergic innervation, the nucleus basalis of Meynert (nbM), ... Read more >>

JAMA Neurol (JAMA neurology)
[2020, 77(2):225-233]

Cited: 6 times

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β-Amyloid PET and neuropathology in dementia with Lewy bodies.

Kejal Kantarci, Val J Lowe, Qin Chen, Scott A Przybelski, Timothy G Lesnick, Christopher G Schwarz, Matthew L Senjem, Jeffrey L Gunter, Clifford R Jack, Jonathan Graff-Radford, David T Jones, David S Knopman, Neill Graff-Radford, Tanis J Ferman, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Bradley F Boeve, Melissa E Murray,

<h4>Objective</h4>β-Amyloid (Aβ) pathology is common in patients with probable dementia with Lewy bodies (DLB). However, the pathologic basis and the differential diagnostic performance of Aβ PET are not established in DLB. Our objective was to investigate the pathologic correlates of <sup>11</sup>C-Pittsburgh compound B(PiB) uptake on PET in cases with antemortem ... Read more >>

Neurology (Neurology)
[2020, 94(3):e282-e291]

Cited: 4 times

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Tau-positron emission tomography correlates with neuropathology findings.

Val J Lowe, Emily S Lundt, Sabrina M Albertson, Hoon-Ki Min, Ping Fang, Scott A Przybelski, Matthew L Senjem, Christopher G Schwarz, Kejal Kantarci, Bradley Boeve, David T Jones, R Ross Reichard, Jessica F Tranovich, Fadi S Hanna Al-Shaikh, David S Knopman, Clifford R Jack, Dennis W Dickson, Ronald C Petersen, Melissa E Murray,

INTRODUCTION:Comparison of tau (flortaucipir) positron emission tomography (FTP-PET) to autopsy is important to demonstrate the relationship of FTP-PET to neuropathologic findings. METHODS:Autopsies were performed on 26 participants who had antemortem FTP-PET. FTP-PET standardized uptake value ratios (SUVRs) were compared to autopsy diagnoses and Braak tangle stage. Quantitative tau burden was ... Read more >>

Alzheimers Dement (Alzheimer's & dementia : the journal of the Alzheimer's Association)
[2020, 16(3):561-571]

Cited: 10 times

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Effect Modifiers of TDP-43-Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes.

Marina Buciuc, Alexandra M Wennberg, Stephen D Weigand, Melissa E Murray, Matthew L Senjem, Anthony J Spychalla, Bradley F Boeve, David S Knopman, Clifford R Jack, Kejal Kantarci, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Jennifer L Whitwell, Keith A Josephs,

BACKGROUND:Transactive response DNA-binding protein of 43 kDa (TDP-43) is associated with hippocampal atrophy in Alzheimer's disease (AD), but whether the association is modified by other factors is unknown. OBJECTIVE:To evaluate whether the associations between TDP-43 and hippocampal volume and atrophy rate are affected by age, gender, apolipoprotein E (APOE) ɛ4, Lewy ... Read more >>

J Alzheimers Dis (Journal of Alzheimer's disease : JAD)
[2020, 73(4):1511-1523]

Cited: 1 time

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Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration.

Alexandre Bejanin, Melissa E Murray, Peter Martin, Hugo Botha, Nirubol Tosakulwong, Christopher G Schwarz, Matthew L Senjem, Gael Chételat, Kejal Kantarci, Clifford R Jack, Bradley F Boeve, David S Knopman, Ronald C Petersen, Caterina Giannini, Joseph E Parisi, Dennis W Dickson, Jennifer L Whitwell, Keith A Josephs,

Over the past decade, the transactive response DNA-binding protein of 43 kDa (TDP-43) has been recognized as a major protein in normal and pathological ageing, increasing the risk of cognitive impairment and dementia. In conditions distinct from the frontotemporal lobar degenerations, TDP-43 appears to progress in a stereotypical pattern. In ... Read more >>

Brain (Brain : a journal of neurology)
[2019, 142(11):3621-3635]

Cited: 7 times

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Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers.

Dennis W Dickson, Matthew C Baker, Jazmyne L Jackson, Mariely DeJesus-Hernandez, NiCole A Finch, Shulan Tian, Michael G Heckman, Cyril Pottier, Tania F Gendron, Melissa E Murray, Yingxue Ren, Joseph S Reddy, Neill R Graff-Radford, Bradley F Boeve, Ronald C Petersen, David S Knopman, Keith A Josephs, Leonard Petrucelli, Björn Oskarsson, John W Sheppard, Yan W Asmann, Rosa Rademakers, Marka van Blitterswijk,

The majority of the clinico-pathological variability observed in patients harboring a repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) remains unexplained. This expansion, which represents the most common genetic cause of frontotemporal lobar degeneration (FTLD) and motor neuron disease (MND), results in a loss of C9orf72 expression and the generation ... Read more >>

Acta Neuropathol Commun (Acta neuropathologica communications)
[2019, 7(1):150]

Cited: 4 times

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