Full Text Journal Articles by
Author Mehmet Tarakcioglu

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Effect of periodontitis on oxidative stress parameters in patients with rheumatic heart valve disease.

Aysegul Sari, Vedat Davutoglu, Emrullah Bozkurt, Mehmet Tarakcioglu, Kamile Erciyas,

OBJECTIVE:The aim of this study was to evaluate the effects of periodontitis on oxidative stress parameters by investigating serum and gingival crevicular fluid (GCF) total antioxidant capacity (TAOC), total oxidant status (TOS), and oxidative stress index (OSI) values in patients with rheumatic heart valve disease (RHVD). MATERIALS AND METHODS:The study ... Read more >>

Arch Oral Biol (Archives of oral biology)
[2020, 121:104961]

Cited: 0 times

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Nigella sativa oil and thymoquinone reduce oxidative stress in the brain tissue of rats exposed to total head irradiation.

Elif Demir, Seyithan Taysi, Hasan Ulusal, Davut Sinan Kaplan, Kadir Cinar, Mehmet Tarakcioglu,

Purpose: To evaluate the antioxidant and radio-protective effects of Nigella sativa oil (NSO) and thymoquinone (TQ) on radiation-induced oxidative stress in brain tissue.Materials and methods: Fifty-four Sprague-Dawley rats were divided into six groups to test the radio-protective effectiveness of Nigella sativa oil and thymoquine administered by either orogastric tube or ... Read more >>

Int J Radiat Biol (International journal of radiation biology)
[2020, 96(2):228-235]

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Idarubicin-bromelain combination sensitizes cancer cells to conventional chemotherapy.

Abdullah Taşkın, Mehmet Tarakçıoğlu, Hasan Ulusal, Mustafa Örkmez, Seyithan Taysı,

Objectives:The primary cytotoxic effects of anticancer drugs like idarubicin, a chemotherapeutic agent, are not limited to neoplastic cells; they also produce similar effects in normal cells. In this study, we hypothesized that the combination of idarubicin-bromelain could make cancer cells more susceptible to cytotoxicity and genotoxicity. Materials and Methods:To test ... Read more >>

Iran J Basic Med Sci (Iranian journal of basic medical sciences)
[2019, 22(10):1172-1178]

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Urinary angiotensinogen level is increased in renal transplant recipients with masked hypertension and is correlated with left ventricular mass index and albuminuria in these patients.

Ozlem Tiryaki, Celalettin Usalan, Seval Kul, Mehmet Tarakcioglu, Murat Sucu, Fahrettin Yildiz, Sacit Coban,

Activation of the local renin-angiotensin system (RAS) is an independent risk factor for the development of proteinuria and left ventricular hypertrophy (LVH) more commonly seen in masked hypertensives. It has been reported that urinary angiotensinogen (UAGT) level provides a specific index of the intrarenal RAS status. The aim of this ... Read more >>

Clin Transplant (Clinical transplantation)
[2018, 32(9):e13375]

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Urinary angiotensinogen level is correlated with blood pressure level and proteinuria in patients with masked hypertension.

Ozlem Tiryaki, Celalettin Usalan, Mehmet Tarakcioglu,

Urinary <AQ: Please check whether all the edits made in this paper convey your intended meaning, and correct if necessary.>angiotensinogen (UAGT) level is an index of the intrarenal-renin angiotensin system status and is significantly correlated with blood pressure (BP) and proteinuria in patients with hypertension (HT). We aimed to investigate ... Read more >>

Clin Exp Hypertens (Clinical and experimental hypertension (New York, N.Y. : 1993))
[2018, 40(7):644-649]

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The acute effects of interval exercise on oxidative stress and antioxidant status in volleyball players.

Ramazan Kocabaş, Emine S Namiduru, Adnan M Bagçeci, Ali K Erenler, Önder Karakoç, Mustafa Örkmez, Müslüm Akan, Hacı K Erdemli, Seyithan Taysi, Mehmet Tarakçioglu,

Volleyball is briefly described as an "interval" sport with both aerobic and anaerobic components. Exercise may influence antioxidant/prooxidant balance, which leads to differences in oxidative stress status between athletes in different sport disciplines, but the results of the previous studies are inconsistent. In this study, we aimed to determine the ... Read more >>

J Sports Med Phys Fitness (The Journal of sports medicine and physical fitness)
[2018, 58(4):421-427]

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The effects of Nigella sativa oil, thymoquinone, propolis, and caffeic acid phenethyl ester on radiation-induced cataract.

Elif Demir, Seyithan Taysi, Behcet Al, Tuncer Demir, Seydi Okumus, Oguzhan Saygili, Edibe Saricicek, Ahmet Dirier, Muslum Akan, Mehmet Tarakcioglu, Cahit Bagci,

The aim of this study was to investigate the antioxidant and radioprotective effects of propolis, caffeic acid phenethyl ester (CAPE), Nigella sativa oil (NSO), and thymoquinone (TQ) against ionizing radiation-induced cataracts in lens after total cranium irradiation of rats with single dose of 5-Gy cobalt-60 gamma rays.A total of 74 ... Read more >>

Wien. Klin. Wochenschr. (Wiener klinische Wochenschrift)
[2016, 128(Suppl 8):587-595]

Cited: 1 time

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The effect of vitamin E and L-carnitine against methotrexate-induced injury in rat testis.

Mehmet Yüncü, Nezahat Bükücü, Nuray Bayat, Leman Sencar, Mehmet Tarakçioğlu,

BACKGROUND/AIM:Methotrexate (MTX), used commonly as an antimetabolite drug in cancer therapy, leads to acute toxic side effects in tissues or organs containing rapidly dividing cells, such as bone marrow, gastrointestinal mucosa, and seminiferous tubules. In this study, we investigated the protective effects of vitamin E and L-carnitine against MTX-induced injury ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2015, 45(3):517-525]

Cited: 2 times

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The radio-protective effects of caffeic acid phenethyl ester and thymoquinone in rats exposed to total head irradiation.

Oztekin Cikman, Seyithan Taysi, Murat Taner Gulsen, Elif Demir, Muslum Akan, Halit Diril, Hasan Ali Kiraz, Muammer Karaayvaz, Mehmet Tarakcioglu,

Many cancer patients treated with radiotherapy suffer severe side effects during and after their treatment. The aim of this study was to investigate the effects of irradiation and the addition of caffeic acid phenethyl ester (CAPE) and thymoquinone (TQ) on the oxidant/antioxidant system in the liver tissue of irradiated rats.A ... Read more >>

Wien. Klin. Wochenschr. (Wiener klinische Wochenschrift)
[2015, 127(3-4):103-108]

Cited: 5 times

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The radioprotective effect of Nigella sativa on nitrosative stress in lens tissue in radiation-induced cataract in rat.

Seyithan Taysi, Zainab Khaleel Abdulrahman, Seydi Okumus, Elif Demir, Tuncer Demir, Muslum Akan, Edibe Saricicek, Vahap Saricicek, Adnan Aksoy, Mehmet Tarakcioglu,

The aim of this study was to investigate the antioxidant and radioprotective effects of Nigella sativa oil (NSO) and thymoquinone (TQ) against ionizing radiation-induced cataracts in lens after total cranium irradiation (IR) of rats with a single dose of 5 gray (Gy).Seventy-four Sprague-Dawley rats were used for the experiment. The ... Read more >>

Cutan Ocul Toxicol (Cutaneous and ocular toxicology)
[2015, 34(2):101-106]

Cited: 4 times

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Radiation-modifying abilities of Nigella sativa and thymoquinone on radiation-induced nitrosative stress in the brain tissue.

Adem Ahlatci, Abdurahman Kuzhan, Seyithan Taysi, Omer Can Demirtas, Hilal Eryigit Alkis, Mehmet Tarakcioglu, Ali Demirci, Derya Caglayan, Edibe Saricicek, Kadir Cinar,

To investigate Nigella sativa oil (NSO) and Thymoquinone (TQ) for their antioxidant effects on the brain tissue of rats exposed to ionizing radiation. Fifty-four male albino Wistar rats, divided into six groups, were designed as group I (normal control group) did not receive NSO, TQ or irradiation; group II (control ... Read more >>

Phytomedicine (Phytomedicine : international journal of phytotherapy and phytopharmacology)
[2014, 21(5):740-744]

Cited: 9 times

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Effects of Leptin on Intestinal Ischemia-Reperfusion Injury.

Sevgi Buyukbese Sarsu, Bulent Hayri Ozokutan, Mehmet Tarakcioglu, Ibrahim Sarı, Cahit Bağcı,

Many clinical conditions such as shock, sepsis, mesenteric thrombosis, necrotizing enterocolitis, and bowel transplantation can cause intestinal ischemia-reperfusion (IR) injury. This study was designed to determine the effects of leptin on intestinal IR injury. Thirty rats were divided into three groups, each containing ten rats: group A (IR group), group ... Read more >>

Indian J Surg (The Indian journal of surgery)
[2015, 77(Suppl 2):351-355]

Cited: 0 times

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Zinc administration modulates radiation-induced oxidative injury in lens of rat.

Seyithan Taysi, Seydi Okumus, Mehmet Akyuz, Naim Uzun, Adnan Aksoy, Elif Demir, Mustafa Orkmez, Mehmet Tarakcioglu, Mustafa Adli,

BACKGROUND:The aim of this study was to evaluate the antioxidant role of zinc (Zn) against radiation-induced cataract in the rat lens after total cranial irradiation with a single 5 Gray (Gy) dose of gamma irradiation. MATERIALS AND METHODS:Twenty-one Sprague-Dawley rats were used for the experiment. The control group did not ... Read more >>

(Pharmacognosy magazine)
[2012, 8(32):245-249]

Cited: 8 times

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Serum leptin, resistin and TNF-α levels in patients with systemic sclerosis: the role of adipokines in scleroderma.

Yavuz Pehlivan, Ahmet Mesut Onat, Nurdan Ceylan, Ibrahim Halil Turkbeyler, Hakan Buyukhatipoglu, Gazi Comez, Taner Babacan, Mehmet Tarakcioglu,

AIM: Systemic sclerosis (SSc) is a chronic fibrotic collagen tissue disease. Leptin's role in regulating immune and inflammatory response has become increasingly evident. Resistin has pro-inflammatory properties and also is associated with inflammatory markers in some rheumatologic diseases. The purpose of this study was to determine serum leptin, resistin and ... Read more >>

Int J Rheum Dis (International journal of rheumatic diseases)
[2012, 15(4):374-379]

Cited: 21 times

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Visfatin levels in Behcet's disease.

Hatice Sezen, Seydi Okumus, Yavuz Pehlivan, Ismail Dilli, Mehmet Tarakcioğlu, Ahmet Mesut Onat,

The aim of our study is to determine the serum visfatin levels of patients with Behcet's disease and to investigate the relationship between visfatin, an adipokine released from adipose tissue, levels and activity of Behcet's disease. Fifty-eight patients with Behcet's disease were enrolled to the study. Nineteen of the patients ... Read more >>

Inflammation (Inflammation)
[2012, 35(2):405-408]

Cited: 5 times

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Effect of chronic periodontitis on oxidative status in patients with rheumatoid arthritis.

Ufuk Sezer, Kamile Erciyas, Kemal Ustün, Yavuz Pehlivan, Süleyman Ziya Şenyurt, Nurten Aksoy, Mehmet Tarakçıoğlu, Seyithan Taysı, Ahmet Mesut Onat,

BACKGROUND: Rheumatoid arthritis (RA) and chronic periodontitis (CP) are the most common chronic inflammatory diseases and have remarkable similar pathologies. The aim of this study is to investigate the impact of periodontal status on oxidative stress in patients with RA by evaluating serum oxidative parameters and prolidase levels. METHODS: For ... Read more >>

J. Periodontol. (Journal of periodontology)
[2013, 84(6):785-792]

Cited: 13 times

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Levels of malondialdehyde, myeloperoxidase and nitrotyrosine in patients with chronic viral hepatitis B and C.

Emine S Namiduru, Mustafa Namiduru, Mehmet Tarakçioğlu, Mustafa Tanriverdi,

OBJECTIVES: Oxidative stress is one of the potential biochemical mechanisms involved in the pathogenesis of chronic viral hepatitis. The aim of the present study was to determine levels of oxidative stress in a large group of chronic viral hepatitis (CVH) patients who had not received antiviral treatment, and to assess ... Read more >>

Adv Clin Exp Med (Advances in clinical and experimental medicine : official organ Wroclaw Medical University)
[2012, 21(1):47-53]

Cited: 3 times

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The relation between serum cytokeratin 18 and acute pancreatitis: can it be a serological predictive marker?

İrfan Koruk, Hakan Özdemır, Musa Aydinli, Neslihan Bekmen, Mehmet Tarakçioğlu, Mehmet Koruk,

BACKGROUND/AIMS:Acute pancreatitis is well defined as pancreatic inflammation due to the activation of pancreatic enzymes secondary to several etiological factors. In the majority of patients, the clinical symptoms are self-limited, but it can also cause tissue necrosis and severe organ failures. In experimental animal models, it has been shown that ... Read more >>

Turk J Gastroenterol (The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology)
[2012, 23(6):759-763]

Cited: 1 time

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Protective effects of Y-27632 on hypoxia/reoxygenation-induced intestinal injury in newborn rats.

Gül Balyemez, Ercan Sivasli, Haluk Ceylan, Ediz Tutar, Sule Ekiz, Mehmet Tarakcioglu, Abdullah T Demiryurek, M Yavuz Coskun,

Necrotizing enterocolitis (NEC) is a major cause of mortality in neonates and is associated with a disruption in the protective intestinal barrier. The precise cause of NEC is elusive. However, ischemia/reperfusion injury of the intestine has been considered a major contributing factor. We examined the role of Y-27632, a selective ... Read more >>

J Pediatr Surg (Journal of pediatric surgery)
[2011, 46(8):1490-1494]

Cited: 6 times

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Increased urotensin-II activity in patients with Raynaud's phenomenon and systemic lupus erythematosus.

Hakan Buyukhatipoglu, Hasan Buyukaslan, Yavuz Pehlivan, Nurdan Ceylan, Turgay Ulas, Mehmet Tarakcioglu, Ahmet M Onat,

AIM:Raynaud's phenomenon (RP) commonly co-exists with systemic lupus erythematosus (SLE). The obvious pathophysiological mechanism in RP is vasoconstriction. Although the roles of certain vasoconstrictor substances, like endothelin-1, have been identified in RP, underlying mechanisms remain unclear. METHODS:In this pilot study, we researched a relatively recently identified, very potent vasoconstrictor peptide, ... Read more >>

Int J Rheum Dis (International journal of rheumatic diseases)
[2011, 14(3):276-281]

Cited: 1 time

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Prognostic value of pleural effusion, CA-125 and NT-proBNP in patients with acute decompensated heart failure.

Vedat Davutoglu, Cuma Yildirim, Hasan Kucukaslan, Murat Yuce, Ibrahim Sari, Mehmet Tarakcioglu, Murat Akcay, Musa Cakici, Nurdan Ceylan, Behcet Al,

BACKGROUND: Acute decompensated heart failure (HF) is a serious complication associated with significant morbidity and mortality. The CA-125 and NT-proBNP levels have been shown in some studies to predict the outcome, however, the prognostic value of other simple clinical parameters such as pleural effusion has not been established yet. AIM: ... Read more >>

Kardiol Pol (Kardiologia polska)
[2010, 68(7):771-778]

Cited: 10 times

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Protective effects of dexpanthenol and y-27632 on stricture formation in a rat model of caustic esophageal injury.

Haluk Ceylan, Sefa Yapici, Ediz Tutar, Nurdan Ozlu Ceylan, Mehmet Tarakçıoğlu, A Tuncay Demiryurek,

BACKGROUND: This experimental study was conducted to investigate the effect of dexpanthenol (converted in the body to pantothenic acid) and Y-27632 (a selective Rho-kinase inhibitor) on stricture formation after caustic (alkaline) esophageal injury in rats. MATERIALS AND METHODS: Sixty male Wistar albino rats were randomly allocated into six groups. In ... Read more >>

J. Surg. Res. (The Journal of surgical research)
[2011, 171(2):517-523]

Cited: 9 times

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Antioxidant defense in patients with chronic viral hepatitis B and C type.

Emine Siber Namiduru, Mustafa Namiduru, Mehmet Tarakçioğlu, Armağan Toy,

BACKGROUND: The aim of the present study was to determine erythrocyte glutathione, superoxide dismutase, catalase, glutathione peroxidase, and serum total antioxidant response levels in a large chronic viral hepatitis group who had no antiviral treatment, and also the relationship of these parameters with viral load, fibrosis score, and necro-inflammation of ... Read more >>

Clin Lab (Clinical laboratory)
[2010, 56(5-6):207-213]

Cited: 2 times

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Formulation of effects of atropine, pralidoxime and magnesium sulfate on cardiac tissue levels of nitric oxide, malondialdehyde and glutathione in organophosphate poisoning using artificial neural network.

Necla Togun, Ataman Kose, Nurullah Gunay, Mehmet Tarakcioglu, Abdullah T Demiryurek,

Anticholinesterase poisoning is an important health problem in our country, and a complete understanding of its underlying mechanisms is essential for the emergency physician. So, this study focused on two purposes. First one was aimed to investigate the biochemical analysis to determine the tissue levels of malondialdehyde (MDA), glutathione and ... Read more >>

Comput Biol Med (Computers in biology and medicine)
[2010, 40(1):29-36]

Cited: 0 times

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Cardiac damage in acute organophosphate poisoning in rats: effects of atropine and pralidoxime.

Ataman Kose, Nurullah Gunay, Cuma Yildirim, Mehmet Tarakcioglu, Ibrahim Sari, Abdullah T Demiryurek,

Anticholinesterase poisoning is an important health problem in our country, and a complete understanding of its underlying mechanisms is essential for the emergency physician. Thus, we aimed to investigate the cardiac biochemical parameters and mortality in dichlorvos-induced poisoning in rats. Rats were randomly divided into 5 groups as control (corn ... Read more >>

Am J Emerg Med (The American journal of emergency medicine)
[2009, 27(2):169-175]

Cited: 9 times

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