Full Text Journal Articles by
Author Megan E McPhee

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Alterations in pronociceptive and antinociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis.

Megan E McPhee, Henrik Bjarke Vaegter, Thomas Graven-Nielsen,

Altered pronociceptive and antinociceptive mechanisms are often implicated in painful conditions and have been increasingly studied over the past decade. For some painful conditions, alterations are well-established, but in populations with low back pain (LBP), there remains considerable debate whether these mechanisms are altered. The present systematic review aimed to ... Read more >>

Pain (Pain)
[2020, 161(3):464-475]

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Recurrent low back pain patients demonstrate facilitated pronociceptive mechanisms when in pain, and impaired antinociceptive mechanisms with and without pain.

Megan E McPhee, Thomas Graven-Nielsen,

Low back pain (LBP) has been inconsistently associated with enhanced pronociceptive and impaired antinociceptive mechanisms. It remains unknown whether alterations are causal, consequential, or coincidental to pain presence. This study investigated pronociceptive and antinociceptive mechanisms in recurrent LBP (RLBP) patients across painful and pain-free periods, compared with age/sex-matched asymptomatic controls. ... Read more >>

Pain (Pain)
[2019, 160(12):2866-2876]

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Alterations in pro-nociceptive and anti-nociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis.

Megan E McPhee, Henrik Bjarke Vaegter, Thomas Graven-Nielsen,

Altered pro-nociceptive and anti-nociceptive mechanisms are often implicated in painful conditions and have been increasingly studied over the past decade. For some painful conditions alterations are well-established, but in low back pain (LBP) populations there remains considerable debate whether these mechanisms are altered. The present systematic review aimed to address ... Read more >>

Pain (Pain)
[2019, :]

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Assessment of conditioned pain modulation in healthy participants and patients with chronic pain: manifestations and implications for pain progression.

Kristian K Petersen, Megan E McPhee, Morten S Hoegh, Thomas Graven-Nielsen,

PURPOSE OF REVIEW:The purpose of this review is to summarize recent findings on conditioned pain modulation (CPM) in humans with a focus on methodology, factors modulating CPM, and the potential for CPM as a clinical marker for pain progression. RECENT FINDINGS:CPM can be evoked by combining different stimulus modalities with ... Read more >>

Curr Opin Support Palliat Care (Current opinion in supportive and palliative care)
[2019, 13(2):99-106]

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