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Author Maurizio Viecca

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Arrhythmogenic Risk and Mechanisms of QT Prolonging Drugs to Treat COVID-19

Marco Schiavone, Alessio Gasperetti, Elisa Gherbesi, Luca Bergamaschi, Roberto Arosio, Gianfranco Mitacchione, Maurizio Viecca, Giovanni B. Forleo,

While looking for a “magic bullet” to treat COVID-19, the massive off-label use of several of drugs in COVID-19, including repurposed antimalarial drugs, immunosuppressive agents, anti-virals and antibacterial agents, have generated concerns in the early phase of the pandemic due a possible arrhythmogenic effects in relation to QTc interval prolongation. ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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Micra-AV leadless pacemaker and atrioventricular (dys)synchrony: A stepwise process.

Gianfranco Mitacchione, Marco Schiavone, Alessio Gasperetti, Diego Ruggiero, Marialessia Denora, Maurizio Viecca, Giovanni Battista Forleo,

Leadless pacemakers have become a major breakthrough in the management of bradyarrhythmia as an attractive alternative to the standard transvenous pacemakers, but safety and long-term outcomes of the new Micra-AV, which is capable guarantee atrioventricular (AV) synchrony, have been poorly described. Hence, we describe how we managed a 57-year-old patient ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2021, 44(10):1738-1742]

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Second-generation laser balloon ablation for the treatment of atrial fibrillation assessed by continuous rhythm monitoring: the LIGHT-AF study.

Giovanni Rovaris, Giuseppe Ciconte, Marco Schiavone, Gianfranco Mitacchione, Alessio Gasperetti, Elena Piazzi, Gabriele Negro, Elisabetta Montemerlo, Roberto Rondine, Mattia Pozzi, Mirko Casiraghi, Sergio De Ceglia, Daniele Giacopelli, Maurizio Viecca, Gabriele Vicedomini, Giovanni B Forleo, Carlo Pappone,

<h4>Aims</h4>Balloon-based technologies have been developed to simplify catheter ablation of atrial fibrillation (AF), to improve the clinical outcome of the procedure and to achieve durable pulmonary vein isolation (PVI). The objective of this study is to evaluate the safety and efficacy of second-generation laser balloon (LB2) ablation in the treatment ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2021, 23(9):1380-1390]

Cited: 1 time

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Subcutaneous implantable cardioverter-defibrillator and defibrillation testing: A propensity-matched pilot study.

Giovanni B Forleo, Alessio Gasperetti, Alexander Breitenstein, Mikael Laredo, Marco Schiavone, Matteo Ziacchi, Julia Vogler, Danilo Ricciardi, Pietro Palmisano, Agostino Piro, Paolo Compagnucci, Xavier Waintraub, Gianfranco Mitacchione, Gianmarco Carrassa, Giulia Russo, Silvana De Bonis, Andrea Angeletti, Antonio Bisignani, Francesco Picarelli, Michela Casella, Edoardo Bressi, Giovanni Rovaris, Leonardo Calò, Luca Santini, Carlo Pignalberi, Carlo Lavalle, Maurizio Viecca, Ennio Pisanò, Iacopo Olivotto, Antonio Curnis, Antonio Dello Russo, Claudio Tondo, Charles J Love, Luigi Di Biase, Jan Steffel, Roland Tilz, Nicolas Badenco, Mauro Biffi,

<h4>Background</h4>To date, only a few comparisons between subcutaneous implantable cardioverter-defibrillator (S-ICD) patients undergoing and those not undergoing defibrillation testing (DT) at implantation (DT+ vs DT-) have been reported.<h4>Objective</h4>The purpose of this study was to compare long-term clinical outcomes of 2 propensity-matched cohorts of DT+ and DT- patients.<h4>Methods</h4>Among consecutive S-ICD patients ... Read more >>

Heart Rhythm (Heart rhythm)
[2021, 18(12):2072-2079]

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Atrioventricular synchronous leadless pacemaker: state of art and broadened indications.

Gianfranco Mitacchione, Marco Schiavone, Alessio Gasperetti, Maurizio Viecca, Antonio Curnis, Giovanni B Forleo,

Leadless pacemakers (LLPMs) have become a major breakthrough in the management of bradyarrhythmia as an attractive alternative to the standard transvenous pacemakers (TV-PMs). Recently, the introduction of a second-generation LLPMs (Micra AV-MC1AVR1) has expanded pacing modes to obtain atrioventricular (AV) synchronous pacing, providing an interesting alternative in the actual scenario ... Read more >>

Rev Cardiovasc Med (Reviews in cardiovascular medicine)
[2021, 22(2):395-401]

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Factors affecting signal quality in implantable cardiac monitors with long sensing vector.

Giovanni B Forleo, Claudia Amellone, Riccardo Sacchi, Leonida Lombardi, Maria Teresa Lucciola, Valentina Scotti, Maurizio Viecca, Marco Schiavone, Daniele Giacopelli, Massimo Giammaria,

<h4>Purpose</h4>Electrical artefacts are frequent in implantable cardiac monitors (ICMs). We analyzed the subcutaneous electrogram (sECG) provided by an ICM with a long sensing vector and factors potentially affecting its quality.<h4>Methods</h4>Consecutive ICM recipients underwent a follow-up where demographics, body mass index (BMI), implant location, and surface ECG were collected. The sECG ... Read more >>

J Arrhythm (Journal of arrhythmia)
[2021, 37(4):1061-1068]

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Response to: COVID-19 re-infection. Vaccinated individuals as a potential source of transmission.

Marco Schiavone, Alessio Gasperetti, Gianfranco Mitacchione, Maurizio Viecca, Giovanni Battista Forleo,

Eur J Clin Invest (European journal of clinical investigation)
[2021, 51(6):e13544]

Cited: 2 times

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HEART FAILURE HOSPITALIZATION RATE REDUCTION DURING COVID-19 PANDEMIC

Andrea D’Amato, Paolo Severino, Andrea Saglietto, Fabrizio D’Ascenzo, Claudia Marini, Marco Schiavone, Nicolò Ghionzoli, Filippo Pirrotta, Francesca Troiano, Margherita Cannillo, Marco Mennuni, Andrea Rognoni, Francesco Rametta, Alessandro Galluzzo, Gianluca Agnes, Fabio Infusino, Mariateresa Pucci, Carlo Lavalle, Luca Cacciotti, Paul Mather, Walter Grosso Marra, Fabrizio Ugo, Giovanni Forleo, Maurizio Viecca, Nuccia Morici, Giuseppe Patti, Gaetano Maria De Ferrari, Alberto Palazzuoli, Massimo Mancone, Francesco Fedele,

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2021, 77(18):791-791]

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[A case of concomitant aortic stenosis and aortic arch aneurysm: a combined endovascular approach].

Maurizio Di Biasi, Vincenzo Vizzi, Guido Gelpi, Alessandro Colombo, Giuseppe Alessandrino, Federica Sabato, Alessio Galli, Maurizio Viecca,

Aortic valve stenosis and aortic aneurysmal disease are increasingly prevalent with advancing age. When associated, their treatment is very challenging. A female patient with previous Tirone-David procedure presented to our hospital with acute heart failure. She was diagnosed with severe aortic stenosis, aneurysm of the aortic arch and the descending ... Read more >>

G Ital Cardiol (Rome) (Giornale italiano di cardiologia (2006))
[2021, 22(5):397-400]

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Impact of prior statin use on clinical outcomes in COVID-19 patients: data from tertiary referral hospitals during COVID-19 pandemic in Italy.

Gianfranco Mitacchione, Marco Schiavone, Antonio Curnis, Marcello Arca, Spinello Antinori, Alessio Gasperetti, Giosuè Mascioli, Paolo Severino, Federica Sabato, Maria M Caracciolo, Gianmarco Arabia, Laura D'Erasmo, Maurizio Viecca, Massimo Mancone, Massimo Galli, Giovanni B Forleo,

<h4>Background</h4>Epidemiological evidence suggests that anti-inflammatory and immunomodulatory properties of statins may reduce the risk of infections and infection-related complications.<h4>Objective</h4>We aimed to assess the impact of prior statin use on coronavirus disease (COVID-19) severity and mortality.<h4>Methods</h4>In this observational multicenter study, consecutive patients hospitalized for COVID-19 were enrolled. In-hospital mortality and severity ... Read more >>

J Clin Lipidol (Journal of clinical lipidology)
[2021, 15(1):68-78]

Cited: 17 times

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QT Interval Monitoring and Drugs Management During COVID-19 Pandemic.

Alessio Gasperetti, Marco Schiavone, Claudio Tondo, Gianfranco Mitacchione, Maurizio Viecca, Massimo Galli, Piercarlo Sarzi-Puttini, Giovanni B Forleo,

While facing potentially high morbidity from COVID-19 without known effective therapies, the off-label use of several non-specific drugs has been advocated, including re-purposed anti- viral (e.g., remdesivir or the lopinavir/ritonavir combination), biologic agents (e.g., tocilizumab), and antimalarial drugs such as chloroquine and hydroxychloroquine, in association with or without azithromycin. Data ... Read more >>

Curr Rev Clin Exp Pharmacol (Current reviews in clinical and experimental pharmacology)
[2021, 16(4):306-317]

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Reduction in heart failure hospitalization rate during coronavirus disease 19 pandemic outbreak.

Paolo Severino, Andrea D'Amato, Andrea Saglietto, Fabrizio D'Ascenzo, Claudia Marini, Marco Schiavone, Nicolò Ghionzoli, Filippo Pirrotta, Francesca Troiano, Margherita Cannillo, Marco Mennuni, Andrea Rognoni, Francesco Rametta, Alessandro Galluzzo, Gianluca Agnes, Fabio Infusino, Mariateresa Pucci, Carlo Lavalle, Luca Cacciotti, Paul J Mather, Walter Grosso Marra, Fabrizio Ugo, Giovanni Forleo, Maurizio Viecca, Nuccia Morici, Giuseppe Patti, Gaetano M De Ferrari, Alberto Palazzuoli, Massimo Mancone, Francesco Fedele,

<h4>Aims</h4>The recent coronavirus disease 19 (COVID-19) pandemic outbreak forced the adoption of restraint measures, which modified the hospital admission patterns for several diseases. The aim of the study is to investigate the rate of hospital admissions for heart failure (HF) during the early days of the COVID-19 outbreak in Italy, ... Read more >>

ESC Heart Fail (ESC heart failure)
[2020, :]

Cited: 10 times

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Redefining the Prognostic Value of High-Sensitivity Troponin in COVID-19 Patients: The Importance of Concomitant Coronary Artery Disease.

Marco Schiavone, Alessio Gasperetti, Massimo Mancone, Aaron V Kaplan, Cecilia Gobbi, Giosuè Mascioli, Mattia Busana, Ardan M Saguner, Gianfranco Mitacchione, Andrea Giacomelli, Gennaro Sardella, Maurizio Viecca, Firat Duru, Spinello Antinori, Stefano Carugo, Antonio L Bartorelli, Claudio Tondo, Massimo Galli, Francesco Fedele, Giovanni B Forleo,

<h4>Background</h4>Although studies assessing cardiovascular comorbidities and myocardial injury in Coronavirus disease 2019 (COVID-19) patients have been published, no reports focused on clinical outcomes of myocardial injury in patients with and without chronic coronary syndromes (CCS) are currently available.<h4>Methods</h4>In this study, consecutive COVID-19 patients admitted to four different institutions were screened ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(10):]

Cited: 11 times

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Neglected lead tip erosion: An unusual case of S-ICD inappropriate shock.

Gianfranco Mitacchione, Marco Schiavone, Alessio Gasperetti, Maurizio Viecca, Antonio Curnis, Giovanni B Forleo,

A 52-year-old man experienced a subcutaneous implantable cardioverter-defibrillator (S-ICD) inappropriate shock due to electrode tip decubitus. The device, implanted two years before with a three-incision technique, was extracted, and a new electrode was implanted along the contralateral parasternal line with a two-incision technique, in a one-stage procedure. One-year follow-up was ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2020, 31(12):3322-3325]

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Acute Coronary Syndromes and Covid-19: Exploring the Uncertainties.

Marco Schiavone, Cecilia Gobbi, Giuseppe Biondi-Zoccai, Fabrizio D'Ascenzo, Alberto Palazzuoli, Alessio Gasperetti, Gianfranco Mitacchione, Maurizio Viecca, Massimo Galli, Francesco Fedele, Massimo Mancone, Giovanni Battista Forleo,

Since an association between myocardial infarction (MI) and respiratory infections has been described for influenza viruses and other respiratory viral agents, understanding possible physiopathological links between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and acute coronary syndromes (ACS) is of the greatest importance. The initial data suggest an underestimation of ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(6):]

Cited: 27 times

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Enhanced platelet inhibition treatment improves hypoxemia in patients with severe Covid-19 and hypercoagulability. A case control, proof of concept study.

Maurizio Viecca, Dejan Radovanovic, Giovanni Battista Forleo, Pierachille Santus,

Patients affected by severe coronavirus induced disease-2019 (Covid-19) often experience hypoxemia due to alveolar involvement and endothelial dysfunction, which leads to the formation of micro thrombi in the pulmonary capillary vessels. Both hypoxemia and a prothrombotic diathesis have been associated with more severe disease and increased risk of death. To ... Read more >>

Pharmacol Res (Pharmacological research)
[2020, 158:104950]

Cited: 49 times

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Impact of multipoint pacing on projected battery longevity in cardiac resynchronization therapy. An IRON-MPP study sub-analysis.

Giovanni B Forleo, Alessio Gasperetti, Danilo Ricciardi, Antonio Curnis, Emanuele Bertaglia, Leonardo Calò, Carlo Pignalberi, Vittorio Calzolari, Valentina Ribatti, Carlo Lavalle, Domenico Potenza, Lara Tondi, Veronica Natale, Pasquale Notarstefano, Maurizio Viecca, Giovanni Morani, Mauro Biffi, Massimo Giammaria, Francesco Zanon, Luca Santini,

<h4>Background</h4>Multipoint pacing (MPP) may improve clinical outcomes in patients with cardiac resynchronization therapy defibrillators (CRT-D), but its impact on battery longevity in a real-world population has not been investigated in large trials.<h4>Objective</h4>Compare projected battery longevity in CRT-D patients with and without MPP during long-term follow-up.<h4>Methods</h4>The Italian registry on multipoint left ... Read more >>

J Cardiovasc Electrophysiol (Journal of cardiovascular electrophysiology)
[2019, 30(12):2885-2891]

Cited: 2 times

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Left atrial appendage occlusion in high-risk patients: doing it is better than nothing.

Vincenzo Vizzi, Maurizio Di Biasi, Giuseppe Alessandrino, Alessandro Colombo, Paolo Danna, Maurizio Viecca,

Heart (Heart (British Cardiac Society))
[2018, 104(7):625]

Cited: 0 times

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Aortic dilatation in Marfan syndrome: role of arterial stiffness and fibrillin-1 variants.

Paolo Salvi, Andrea Grillo, Susan Marelli, Lan Gao, Lucia Salvi, Maurizio Viecca, Anna Maria Di Blasio, Renzo Carretta, Alessandro Pini, Gianfranco Parati,

<h4>Objective</h4>Marfan syndrome (MFS) is an autosomal dominant genetic disorder characterized by aortic root dilation and dissection and an abnormal fibrillin-1 synthesis. In this observational study, we evaluated aortic stiffness in MFS and its association with ascending aorta diameters and fibrillin-1 genotype.<h4>Methods</h4>A total of 116 Marfan adult patients without history of ... Read more >>

J Hypertens (Journal of hypertension)
[2018, 36(1):77-84]

Cited: 8 times

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The Striking Interplay of Hiccup and Patent Foramen Ovale.

Alessandro Colombo, Paolo Danna, Alessandro Cialfi, Davide Sala, Maurizio Viecca,

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2017, 10(10):1063-1065]

Cited: 0 times

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Primary PCI is associated with different cardiac autonomic patterns in relation to the site of myocardial infarction.

Eleonora Tobaldini, Elisa M Fiorelli, Marta Prado, Maddalena A Wu, Andreia Queiroz, Tomas Kara, Giorgio Costantino, Armando Belloni, Lorenzo Campi, Paolo Danna, Roberto Sala, Maurizio Viecca, Nicola Montano,

Reflex alterations of cardiac autonomic modulation have been described after acute myocardial infarction (AMI). The non-homogeneous autonomic innervation of the heart gives reason of different patterns of autonomic modulation depending upon the site of AMI. Conflicting data are available on cardiac autonomic modifications after primary percutaneous coronary intervention (pPCI). We ... Read more >>

Eur J Intern Med (European journal of internal medicine)
[2015, 26(10):792-797]

Cited: 2 times

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A multicenter observational study on the management of hyperglycemia in patients with acute coronary syndrome.

F Avanzini, A Mafrici, E Riva, M G Franzosi, V Milani, V Giudici, G Marelli, G Mariani, P M Piatti, M C Roncaglioni, ,

<h4>Aim</h4>To assess the prevalence, risk and management of hyperglycemia in patients with acute coronary syndrome (ACS).<h4>Methods and results</h4><h4>Design</h4>a multicenter prospective observational study of a representative sample of patients with ACS consecutively admitted to intensive cardiac care units (ICCU).<h4>Setting</h4>31 out of 61 ICCUs in Lombardy, the most heavily populated Italian region. ... Read more >>

Nutr Metab Cardiovasc Dis (Nutrition, metabolism, and cardiovascular diseases : NMCD)
[2015, 25(10):916-923]

Cited: 3 times

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[Interatrial block: an under-recognized electrocardiographic diagnosis with important clinical-therapeutic implications].

Riccardo Proietti, Vincenzo Russo, Antonio Sagone, Maurizio Viecca, David H Spodick,

Interatrial blocks, characterized by P-wave duration ≥120 ms, are a well described but poorly recognized cardiac rhythm disorder. They are caused by a conduction delay between the right and left atria and occur in pandemic proportions in unselected patients. Interatrial blocks correlate with atrial dysfunction and are a predictor of ... Read more >>

G Ital Cardiol (Rome) (Giornale italiano di cardiologia (2006))
[2014, 15(10):561-568]

Cited: 2 times

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Novel nonpharmacologic approaches for stroke prevention in atrial fibrillation: results from clinical trials.

Riccardo Proietti, Jacqueline Joza, Andrea Arensi, Michael Levi, Vincenzo Russo, Apostolos Tzikas, Paolo Danna, Antonio Sagone, Maurizio Viecca, Vidal Essebag,

Atrial fibrillation (AF), the most common cardiac arrhythmia, confers a 5-fold risk of stroke that increases to 17-fold when associated with mitral stenosis. At this time, the most effective long-term solution to protect patients from stroke and thromboembolism is oral anticoagulation, either with vitamin K antagonists (VKAs) or a novel ... Read more >>

Med Devices (Auckl) (Medical devices (Auckland, N.Z.))
[2015, 8:103-114]

Cited: 5 times

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Areal bone mineral density in children and adolescents with Marfan syndrome: evidence of an evolving problem.

Giuliana Trifirò, Susan Marelli, Maurizio Viecca, Stefano Mora, Alessandro Pini,

Marfan syndrome (MFS), an autosomal dominant disorder of connective tissue, is due to defective fibrillin-1. Defects involve the cardiovascular system, the eye, the lungs, and the skeleton. The aim of the current study was to characterize the bone mineral status in children and adolescents with MFS. We performed an observational ... Read more >>

Bone (Bone)
[2015, 73:176-180]

Cited: 4 times

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