Full Text Journal Articles by
Author Matti Karppelin

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Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements.

Juha Rannikko, Ville Holmberg, Matti Karppelin, Pertti Arvola, Reetta Huttunen, Eero Mattila, Niina Kerttula, Teija Puhto, Ülle Tamm, Irma Koivula, Risto Vuento, Jaana Syrjänen, Ulla Hohenthal,

Emerg Infect Dis (Emerging infectious diseases)
[2021, 27(8):]

Cited: 0 times

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Major Amputation Profoundly Increases Mortality in Patients With Diabetic Foot Infection.

Miska Vuorlaakso, Juha Kiiski, Tapani Salonen, Matti Karppelin, Mika Helminen, Ilkka Kaartinen,

<b>Introduction:</b> An acute diabetic foot infection (DFI) is a serious condition and a leading cause of hospitalization and major amputation in patients with diabetes. Aim of this study was to evaluate the long term survival and risk factors for death and amputation after the DFI requiring hospital treatment. <b>Materials and ... Read more >>

Front Surg (Frontiers in surgery)
[2021, 8:655902]

Cited: 0 times

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Pathogens Causing Diabetic Foot Infection and the Reliability of the Superficial Culture.

Miska Laakso, Juha Kiiski, Matti Karppelin, Mika Helminen, Ilkka Kaartinen,

<b><i>Background:</i></b> Diabetic foot infection (DFI) is a severe complication of diabetes and a leading cause of hospitalization in the population with diabetes. Empirical intravenous antibiotic agents are initiated according to guidelines based on previously published data on typical pathogens. Therefore, regular evaluation of the pathogens in DFI and their resistance ... Read more >>

Surg Infect (Larchmt) (Surgical infections)
[2021, 22(3):334-339]

Cited: 1 time

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Periprosthetic Joint Infections as a Consequence of Bacteremia.

Meeri Honkanen, Esa Jämsen, Matti Karppelin, Reetta Huttunen, Antti Eskelinen, Jaana Syrjänen,

<h4>Background</h4>The risk for developing a periprosthetic joint infection (PJI) during bacteremia is unclear, except for <i>Staphylococcus aureus</i> bacteremia. The aim of this study was to examine the risk for developing a PJI during bacteremia and to identify possible risk factors leading to it.<h4>Methods</h4>Patients with a primary knee or hip joint ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(6):ofz218]

Cited: 3 times

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Concordance between the old and new diagnostic criteria for periprosthetic joint infection.

Meeri Honkanen, Esa Jämsen, Matti Karppelin, Reetta Huttunen, Outi Lyytikäinen, Jaana Syrjänen,

<h4>Purpose</h4>There is no uniform definition for periprosthetic joint infection (PJI). New diagnostic criteria were formulated in an international consensus meeting in 2013 and adopted by Centers for Disease Control (CDC) in 2016. The purpose of this study is to compare the new diagnostic criteria with the old CDC criteria from ... Read more >>

Infection (Infection)
[2017, 45(5):637-643]

Cited: 6 times

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Predictors of recurrent cellulitis in five years. Clinical risk factors and the role of PTX3 and CRP.

Matti Karppelin, Tuula Siljander, Janne Aittoniemi, Mikko Hurme, Reetta Huttunen, Heini Huhtala, Juha Kere, Jaana Vuopio, Jaana Syrjänen,

<h4>Objectives</h4>To identify risk factors for recurrence of cellulitis, and to assess the predictive value of pentraxin 3 (PTX3) and C-reactive protein (CRP) measured at baseline.<h4>Methods</h4>A follow up study of 90 hospitalised patients with acute non-necrotising cellulitis was conducted. Clinical risk factors were assessed and PTX3 and CRP values were measured ... Read more >>

J Infect (The Journal of infection)
[2015, 70(5):467-473]

Cited: 4 times

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Response to Agilli and Aydin.

Matti Karppelin, Jaana Syrjänen,

J Infect (The Journal of infection)
[2015, 70(5):547-549]

Cited: 0 times

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Genetic susceptibility to non-necrotizing erysipelas/cellulitis.

Katariina Hannula-Jouppi, Satu Massinen, Tuula Siljander, Siru Mäkelä, Katja Kivinen, Rasko Leinonen, Hong Jiao, Päivi Aitos, Matti Karppelin, Jaana Vuopio, Jaana Syrjänen, Juha Kere,

<h4>Background</h4>Bacterial non-necrotizing erysipelas and cellulitis are often recurring, diffusely spreading infections of the skin and subcutaneous tissues caused most commonly by streptococci. Host genetic factors influence infection susceptibility but no extensive studies on the genetic determinants of human erysipelas exist.<h4>Methods</h4>We performed genome-wide linkage with the 10,000 variant Human Mapping Array ... Read more >>

PLoS One (PloS one)
[2013, 8(2):e56225]

Cited: 4 times

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Acquisition of complement factor H is important for pathogenesis of Streptococcus pyogenes infections: evidence from bacterial in vitro survival and human genetic association.

Karita Haapasalo, Jaana Vuopio, Jaana Syrjänen, Jari Suvilehto, Satu Massinen, Matti Karppelin, Irma Järvelä, Seppo Meri, Juha Kere, T Sakari Jokiranta,

Streptococcus pyogenes (or group A streptococcus [GAS]) is a major human pathogen causing infections, such as tonsillitis, erysipelas, and sepsis. Several GAS strains bind host complement regulator factor H (CFH) via its domain 7 and, thereby, evade complement attack and C3b-mediated opsonophagocytosis. Importance of CFH binding for survival of GAS ... Read more >>

J Immunol (Journal of immunology (Baltimore, Md. : 1950))
[2012, 188(1):426-435]

Cited: 25 times

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Acute bacterial, nonnecrotizing cellulitis in Finland: microbiological findings.

Tuula Siljander, Matti Karppelin, Susanna Vähäkuopus, Jaana Syrjänen, Maija Toropainen, Juha Kere, Risto Vuento, Tapio Jussila, Jaana Vuopio-Varkila,

<h4>Background</h4>Bacterial, nonnecrotizing cellulitis is a localized and often recurrent infection of the skin. The aim of this study was to identify the beta-hemolytic streptococci that cause acute nonnecrotizing cellulitis infection in Finland.<h4>Methods</h4>A case-control study of 90 patients hospitalized for acute cellulitis and 90 control subjects was conducted during the period ... Read more >>

Clin Infect Dis (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2008, 46(6):855-861]

Cited: 28 times

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An outbreak of Streptococcus equi subspecies zooepidemicus associated with consumption of fresh goat cheese.

Markku Kuusi, Elina Lahti, Anni Virolainen, Maija Hatakka, Risto Vuento, Leila Rantala, Jaana Vuopio-Varkila, Eija Seuna, Matti Karppelin, Marjaana Hakkinen, Johanna Takkinen, Veera Gindonis, Kyosti Siponen, Kaisa Huotari,

<h4>Background</h4>Streptococcus equi subspecies zooepidemicus is a rare infection in humans associated with contact with horses or consumption of unpasteurized milk products. On October 23, 2003, the National Public Health Institute was alerted that within one week three persons had been admitted to Tampere University Central Hospital (TaYS) because of S. ... Read more >>

BMC Infect Dis (BMC infectious diseases)
[2006, 6:36]

Cited: 32 times

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