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Author Matthew Ziegelmann

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Long-term Success With Diminished Opioid Prescribing After Implementation of Standardized Postoperative Opioid Prescribing Guidelines: An Interrupted Time Series Analysis.

Bridget L Findlay, Cameron J Britton, Amy E Glasgow, Matthew T Gettman, Mark D Tyson, Raymond W Pak, Boyd R Viers, Elizabeth B Habermann, Matthew J Ziegelmann,

<h4>Objective</h4>To assess longitudinal prescribing patterns for patients undergoing urologic surgery in the nearly 2-year time frame before and after implementation of an evidence-based opioid prescribing guideline to accurately characterize the impact on postoperative departmental practices.<h4>Patients and methods</h4>Historical prescribing data for adults who underwent 21 urologic procedures at 3 academic institutions ... Read more >>

Mayo Clin Proc (Mayo Clinic proceedings)
[2021, 96(5):1135-1146]

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EDITORIAL COMMENTS.

Matthew J Ziegelmann,

Urology (Urology)
[2021, 152:23]

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Amir Toussi, Matthew Ziegelmann, David Yang, Madeleine Manka, Igor Frank, Stephen A Boorjian, Matthew Tollefson, Tobias Köhler, Landon Trost,

J Urol (The Journal of urology)
[2021, :101097JU000000000000179203]

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Efficacy of a Novel Penile Traction Device in Improving Penile Length and Erectile Function Post Prostatectomy: Results from a Single-Center Randomized, Controlled Trial.

Amir Toussi, Matthew Ziegelmann, David Yang, Madeleine Manka, Igor Frank, Stephen A Boorjian, Matthew Tollefson, Tobias Köhler, Landon Trost,

<h4>Purpose</h4>RestoreX is a novel penile traction therapy device, with randomized, controlled data demonstrating improvements in penile length and erectile function after 30 to 90 minutes of daily use in men with Peyronie's disease. We sought to determine if similar improvements could be achieved post prostatectomy.<h4>Materials and methods</h4>Men post prostatectomy were ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001792]

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Continuing Collagenase Clostridium Histolyticum Injections Among Initial Nonresponders Results in Significant Curvature Improvements in the Majority of Peyronie's Disease Men.

Manaf Alom, Holli Burgon, Matthew Ziegelmann, Tobias Köhler, Sevann Helo, Landon Trost,

<h4>Background</h4>It is currently unclear if men with Peyronie's Disease (PD) who achieve minimal benefits with the first 2 series of Collagenase Clostridium Histolyticum (CCH) injections should continue with additional injections.<h4>Aim</h4>To analyze curvature improvements from the final two series of CCH injections based on amount of improvement during the first 2 ... Read more >>

J Sex Med (The journal of sexual medicine)
[2021, :]

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Current practices regarding corporotomy localization during penoscrotal inflatable penile implant surgery: a multicenter cohort study.

Koenraad van Renterghem, Brecht Jacobs, Faysal Yafi, Daniar Osmonov, David Ralph, Luca Venturino, John Taylor Barnard, Matthew Ziegelmann, Run Wang, Chris Kannady, Aaron Lentz, Enrique Lledo Garcia, Robert Andrianne, Carlo Bettochi, George Hatzichristodoulou, Martin Gross, Antoine Faix, Javier Romero Otero, Juan Ignacio Martinez Salamanca, Omidreza Sedigh, Maarten Albersen, Marij Dinkelman-Smit, Ioannis Mykoniatis,

Literature concerning corporotomy location in multicomponent inflatable penile prosthetic surgery via a penoscrotal approach is scarce if not nonexistent. Aim of our study was to report practices in low-, moderate-, and high-volume penile implant centers regarding corporotomy location and evaluate its potential impact on intraoperative and short-term postoperative complications. Data ... Read more >>

Int J Impot Res (International journal of impotence research)
[2021, :]

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Patient Attitudes Towards Surgical Management of Peyronie's Disease Prior to Men's Health Consultation.

Raevti Bole, Masaya Jimbo, Niki Parikh, Cameron Britton, Ajay Gopalakrishna, David Yang, Landon Trost, Sevann Helo, Tobias Kohler, Matthew Ziegelmann,

<h4>Objective</h4>To evaluate clinical characteristics associated with patient attitudes toward surgical treatment of Peyronie's disease (PD) prior to consultation in a high-volume male sexual health clinic.<h4>Methods</h4>From 2014-2018 a prospective database was created of patients presenting to the sexual health clinic at our institution. Multivariable regression analysis was conducted to determine factors ... Read more >>

Urology (Urology)
[2021, :]

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Vascular Necrosis of the Upper Extremity After Self-Treatment for Peyronie's Disease.

David Yang, Joshua Savage, Tobias Köhler, Sevann Helo, Landon Trost, Matthew Ziegelmann,

Peyronie's disease (PD) is associated with significant psychosocial distress, including anxiety, depression, and negative effects on interpersonal relationships. We report outcomes in a patient who researched an enzymatic supplement intended for oral administration for treatment of PD and subsequently self-injected it intravascularly. The enzyme, a combination of serrapeptase and nattokinase, ... Read more >>

Sex Med (Sexual medicine)
[2021, 9(1):100282]

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Comparing and Contrasting Peyronie's Disease Guidelines: Points of Consensus and Deviation.

Madeleine G Manka, Lindsay A White, Faysal A Yafi, John P Mulhall, Laurence A Levine, Matthew J Ziegelmann,

<h4>Background</h4>Peyronie's disease (PD) is a challenging clinical entity. To assist clinicians with diagnosis and management, four separate organizations have published PD guidelines over the past five years, but there remains a lack of consensus and data-driven recommendations for many aspects of diagnosis and treatment.<h4>Aim</h4>To compare and contrast PD guidelines, highlighting ... Read more >>

J Sex Med (The journal of sexual medicine)
[2021, 18(2):363-375]

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Chronic Scrotal Content Pain: a Review of the Literature and Management Schemes.

Paul J Oh, Petar Bajic, Scott D Lundy, Matthew Ziegelmann, Laurence A Levine,

<h4>Purpose of review</h4>Chronic scrotal content pain (CSCP) is a complex condition with multiple etiologies that requires a thorough understanding of its pathophysiology, workup, and treatment options. We performed a comprehensive and contemporary review to augment our current understanding of CSCP.<h4>Recent findings</h4>We discuss new advances in CSCP-specific pain questionnaires, modern studies ... Read more >>

Curr Urol Rep (Current urology reports)
[2021, 22(2):12]

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Long-acting liposomal bupivacaine and postoperative opioid use after Peyronie's disease surgery: a pilot study.

Cameron J Britton, Bridget L Findlay, Niki Parikh, Tobias Kohler, Sevann Helo, Matthew J Ziegelmann,

<h4>Background</h4>Novel strategies have been proposed to minimize postoperative opioid use, yet many patients experience significant pain after penile surgery. Our objective was to evaluate postoperative opioid use in patients undergoing penile ring block with long-acting liposomal bupivacaine (LB; Exparel) during surgery for Peyronie's disease (PD).<h4>Methods</h4>We identified patients who underwent tunica ... Read more >>

Transl Androl Urol (Translational andrology and urology)
[2021, 10(1):174-183]

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Conservative management of suspected fractures in men undergoing collagenase clostridium histolyticum for Peyronie's Disease is not associated with worsening of erectile function.

Kiran L Sharma, Raevti Bole, David Yang, Manaf Alom, Joshua Savage, Matthew Ziegelmann, Landon Trost,

The optimal management of suspected penile fractures post collagenase clostridium histolyticum (CCH) remains indeterminate, with some advocating for observation and others surgical repair. To address this issue, the current study sent surveys to 158 men with Peyronie's Disease (PD) who completed four CCH injection series. The survey included the Erectile ... Read more >>

Int J Impot Res (International journal of impotence research)
[2020, :]

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Outcomes of RestoreX Penile Traction Therapy in Men With Peyronie's Disease: Results From Open Label and Follow-up Phases.

Jason Joseph, Matthew J Ziegelmann, Manaf Alom, Joshua Savage, Tobias S Köhler, Landon Trost,

<h4>Background</h4>A randomized, controlled clinical trial evaluating the efficacy of RestoreX traction therapy in men with Peyronie's disease (PD) has been completed, with the 3-month results previously reported. The present study presents outcomes from the open-label and follow-up phases of the original trial.<h4>Aim</h4>To report 6-month (open-label phase) and 9-month (follow-up phase) ... Read more >>

J Sex Med (The journal of sexual medicine)
[2020, 17(12):2462-2471]

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Peyronie's Disease and the Female Sexual Partner: A Comparison of the Male and Female Experience.

M Ryan Farrell, Matthew J Ziegelmann, Petar Bajic, Laurence A Levine,

<h4>Background</h4>Peyronie's disease (PD) is characterized by penile pain, deformity, and sexual dysfunction, often resulting in an impaired sexual experience and significant psychological bother for the patient. However, there are limited data on the impact of PD on female sexual partners (FSPs).<h4>Aim</h4>To compare the psychosexual experience of men with PD and ... Read more >>

J Sex Med (The journal of sexual medicine)
[2020, 17(12):2456-2461]

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Predictors of Patient Willingness to Consider Surgery Prior to Consultation at Sexual Health Clinic.

Raevti Bole, Matthew Ziegelmann, Ajay Gopalakrishna, Charles Scott Collins, Manaf Alom, Landon Trost, Sevann Helo, Tobias S Köhler,

<h4>Objective</h4>To identify factors associated with patient willingness to consider surgical treatment for erectile dysfunction (ED) prior to urologic consultation.<h4>Methods</h4>A prospective database of patients presenting to the sexual health clinic at our institution was created from 2014 to 2018, consisting of previsit patient questionnaires and clinical information. Univariable and multivariable logistic ... Read more >>

Urology (Urology)
[2021, 147:172-177]

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Malpractice Litigation in Iatrogenic Ureteral Injury: a Legal Database Review.

Raevti Bole, Brian J Linder, Ajay Gopalakrishna, Ruby Kuang, Ashton L Boon, Elizabeth B Habermann, Matthew J Ziegelmann, Matthew T Gettman, Douglas A Husmann, Boyd R Viers, ,

<h4>Objective</h4>To examine the factors associated with iatrogenic ureteral injury litigation and outcomes.<h4>Methods</h4>The Westlaw legal database was queried for all iatrogenic ureteral injury cases. Variables extracted included available clinical factors, method of settlement, and litigation outcomes. Linear regression analysis was conducted to examine factors associated with award amount.<h4>Results</h4>A total of 522 ... Read more >>

Urology (Urology)
[2020, 146:19-24]

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Safety and Efficacy of Collagenase Clostridium histolyticum in the Treatment of Acute Phase Peyronie's Disease: A Multi-institutional Analysis.

Hoang Minh Tue Nguyen, Ayad Yousif, Amanda Chung, Ramón Virasoro, Ashley Tapscott, Matthew Ziegelmann, Landon Trost, Martin Gelbard, Wayne J G Hellstrom,

OBJECTIVE:To study, in a multi-institutional setting, the efficacy/safety outcomes in acute phase Peyronie's disease (PD) of multiple high-volume centers employing CCH to treat PD, which is defined as the abnormal formation of fibrous plaque(s) in the tunica albuginea of the penis. It is a chronic condition that afflicts 3%-13% of ... Read more >>

Urology (Urology)
[2020, 145:147-151]

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Discrepancy between Post-Vasectomy Semen Analysis Recommendation and Practice Patterns in the Post-2012 American Urological Association Guideline Era.

Madeleine G Manka, Adam Miller, Vidit Sharma, Mohit Butaney, Landon Trost, Matthew Ziegelmann,

PURPOSE:In 2012 the American Urological Association published vasectomy guidelines to promote best practices, including when to obtain post-vasectomy semen analyses. In this study we assessed practice patterns of post-vasectomy semen analysis since this guideline publication. MATERIALS AND METHODS:We retrospectively analyzed a database of men who underwent post-vasectomy semen analysis between ... Read more >>

J Urol (The Journal of urology)
[2020, 204(6):1312-1317]

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Opioid prescribing after urologic surgery: we are part of the problem and part of the solution-an invited commentary on "an opioid prescription for men undergoing minor urologic surgery is associated with an increased risk of new persistent opioid use".

Matthew J Ziegelmann, Bridget L Findlay, Cameron J Britton, Elizabeth B Habermann,

Transl Androl Urol (Translational andrology and urology)
[2020, 9(3):997-1000]

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A Review of Treatment-Related Outcomes in Female Partners of Men With Peyronie's Disease-An Opportunity for Improved Assessment.

Niki N Parikh, Daniel L Heslop, Petar Bajic, Raevti Bole, Michael R Farrell, Laurence A Levine, Matthew J Ziegelmann,

<h4>Introduction</h4>Peyronie's disease (PD) is a disorder of the penile tunica albuginea, causing penile deformity, shortening, pain, and sexual dysfunction. While studies have shown treatment efficacy for patients, research on treatment-related outcomes for sexual partners is lacking.<h4>Objectives</h4>We sought to review the literature on clinical characteristics and treatment-related outcomes from the perspective ... Read more >>

Sex Med Rev (Sexual medicine reviews)
[2020, 8(4):548-560]

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Amphetamine/Dextroamphetamine Salts for Delayed Orgasm and Anorgasmia in Men: A Pilot Study.

Laurence A Levine, Hannah K Betcher, Matthew J Ziegelmann, Petar Bajic,

OBJECTIVE:To describe our experience with amphetamine/dextroamphetamine salts (AMP) as a treatment for delayed orgasm/anorgasmia (DO/AO). METHODS:We identified patients with DO/AO from September 2017 to September 2019. Baseline characteristics and patient-reported orgasmic latency time (OLT) were recorded. After extensive screening, patients were treated with AMP. Validated questionnaires were administered including International ... Read more >>

Urology (Urology)
[2020, 142:141-145]

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Comparative Postoperative Outcomes of Rezūm Prostate Ablation in Patients with Large Versus Small Glands.

Raevti Bole, Ajay Gopalakrishna, Ruby Kuang, Jamal Alamiri, David Y Yang, Sevann Helo, Matthew J Ziegelmann, Tobias S Köhler,

<b><i>Introduction:</i></b> Rezūm water vapor thermal ablation is a new minimally invasive technique used to treat benign prostatic hyperplasia. Major advantages include minimal anesthesia and recovery time, low rate of sexual side effects, and durable clinical improvement. However, data are lacking regarding use of Rezūm in prostate glands >80 cc. Here ... Read more >>

J Endourol (Journal of endourology)
[2020, 34(7):778-781]

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Characteristics of men who are bothered by rapid ejaculation: results from clinical intake surveys.

Ajay Gopalakrishna, Raevti Bole, Manaf Alom, Yifan Meng, Masaya Jimbo, Landon Trost, Sevann Helo, Tobias Kohler, Matthew Ziegelmann,

The objective of this study is to identify factors associated with bother with rapid ejaculation in a cohort of men presenting to a sexual dysfunction clinic, independent of a diagnosis of PE. A prospective institutional database has been maintained on patients completing an 89-item intake questionnaire querying various areas of ... Read more >>

Int J Impot Res (International journal of impotence research)
[2021, 33(3):369-375]

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Use of Nitrous Oxide in Office-based Urologic Procedures: A Review.

Ajay Gopalakrishna, Raevti Bole, Roy Lipworth, Masaya Jimbo, Sevann Helo, Tobias Kohler, Matthew Ziegelmann,

Nitrous oxide (N2O) is underutilized in ambulatory urology. Here, we review available data regarding application, efficacy, and side effect profile of N2O in ambulatory urologic procedures. Data were available from 11 studies. N2O has been described in the setting of transrectal ultrasound-guided prostate biopsies, flexible cystoscopy, ureteral stent placement, and ... Read more >>

Urology (Urology)
[2020, 143:33-41]

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A modern review of penile traction monotherapy and combination therapy for the treatment of peyronie's disease.

Raevti Bole, Lindsay White, Niki Parikh, Sevann Helo, Tobias Kohler, Matthew Ziegelmann,

Peyronie's disease (PD)-related penile deformity is managed with multiple treatment modalities including oral medications, intralesional injections, and surgery. Penile traction therapy (PTT) is one such modality with purported benefits, albeit with notable differences in the characteristics of available traction devices and published study protocols. We provide a comprehensive review of ... Read more >>

Int J Impot Res (International journal of impotence research)
[2021, 33(3):251-258]

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