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AusTraits, a curated plant trait database for the Australian flora.

Daniel Falster, Rachael Gallagher, Elizabeth H Wenk, Ian J Wright, Dony Indiarto, Samuel C Andrew, Caitlan Baxter, James Lawson, Stuart Allen, Anne Fuchs, Anna Monro, Fonti Kar, Mark A Adams, Collin W Ahrens, Matthew Alfonzetti, Tara Angevin, Deborah M G Apgaua, Stefan Arndt, Owen K Atkin, Joe Atkinson, Tony Auld, Andrew Baker, Maria von Balthazar, Anthony Bean, Chris J Blackman, Keith Bloomfield, David M J S Bowman, Jason Bragg, Timothy J Brodribb, Genevieve Buckton, Geoff Burrows, Elizabeth Caldwell, James Camac, Raymond Carpenter, Jane A Catford, Gregory R Cawthray, Lucas A Cernusak, Gregory Chandler, Alex R Chapman, David Cheal, Alexander W Cheesman, Si-Chong Chen, Brendan Choat, Brook Clinton, Peta L Clode, Helen Coleman, William K Cornwell, Meredith Cosgrove, Michael Crisp, Erika Cross, Kristine Y Crous, Saul Cunningham, Timothy Curran, Ellen Curtis, Matthew I Daws, Jane L DeGabriel, Matthew D Denton, Ning Dong, Pengzhen Du, Honglang Duan, David H Duncan, Richard P Duncan, Marco Duretto, John M Dwyer, Cheryl Edwards, Manuel Esperon-Rodriguez, John R Evans, Susan E Everingham, Claire Farrell, Jennifer Firn, Carlos Roberto Fonseca, Ben J French, Doug Frood, Jennifer L Funk, Sonya R Geange, Oula Ghannoum, Sean M Gleason, Carl R Gosper, Emma Gray, Philip K Groom, Saskia Grootemaat, Caroline Gross, Greg Guerin, Lydia Guja, Amy K Hahs, Matthew Tom Harrison, Patrick E Hayes, Martin Henery, Dieter Hochuli, Jocelyn Howell, Guomin Huang, Lesley Hughes, John Huisman, Jugoslav Ilic, Ashika Jagdish, Daniel Jin, Gregory Jordan, Enrique Jurado, John Kanowski, Sabine Kasel, Jürgen Kellermann, Belinda Kenny, Michele Kohout, Robert M Kooyman, Martyna M Kotowska, Hao Ran Lai, Etienne Laliberté, Hans Lambers, Byron B Lamont, Robert Lanfear, Frank van Langevelde, Daniel C Laughlin, Bree-Anne Laugier-Kitchener, Susan Laurance, Caroline E R Lehmann, Andrea Leigh, Michelle R Leishman, Tanja Lenz, Brendan Lepschi, James D Lewis, Felix Lim, Udayangani Liu, Janice Lord, Christopher H Lusk, Cate Macinnis-Ng, Hannah McPherson, Susana Magallón, Anthony Manea, Andrea López-Martinez, Margaret Mayfield, James K McCarthy, Trevor Meers, Marlien van der Merwe, Daniel J Metcalfe, Per Milberg, Karel Mokany, Angela T Moles, Ben D Moore, Nicholas Moore, John W Morgan, William Morris, Annette Muir, Samantha Munroe, Áine Nicholson, Dean Nicolle, Adrienne B Nicotra, Ülo Niinemets, Tom North, Andrew O'Reilly-Nugent, Odhran S O'Sullivan, Brad Oberle, Yusuke Onoda, Mark K J Ooi, Colin P Osborne, Grazyna Paczkowska, Burak Pekin, Caio Guilherme Pereira, Catherine Pickering, Melinda Pickup, Laura J Pollock, Pieter Poot, Jeff R Powell, Sally A Power, Iain Colin Prentice, Lynda Prior, Suzanne M Prober, Jennifer Read, Victoria Reynolds, Anna E Richards, Ben Richardson, Michael L Roderick, Julieta A Rosell, Maurizio Rossetto, Barbara Rye, Paul D Rymer, Michael A Sams, Gordon Sanson, Hervé Sauquet, Susanne Schmidt, Jürg Schönenberger, Ernst-Detlef Schulze, Kerrie Sendall, Steve Sinclair, Benjamin Smith, Renee Smith, Fiona Soper, Ben Sparrow, Rachel J Standish, Timothy L Staples, Ruby Stephens, Christopher Szota, Guy Taseski, Elizabeth Tasker, Freya Thomas, David T Tissue, Mark G Tjoelker, David Yue Phin Tng, Félix de Tombeur, Kyle Tomlinson, Neil C Turner, Erik J Veneklaas, Susanna Venn, Peter Vesk, Carolyn Vlasveld, Maria S Vorontsova, Charles A Warren, Nigel Warwick, Lasantha K Weerasinghe, Jessie Wells, Mark Westoby, Matthew White, Nicholas S G Williams, Jarrah Wills, Peter G Wilson, Colin Yates, Amy E Zanne, Graham Zemunik, Kasia Ziemińska,

We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance ... Read more >>

Sci Data (Scientific data)
[2021, 8(1):254]

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Evolving Chest Pain in a Young Male.

Matthew White, Anthony M Reginato, Joanne S Cunha,

A 33-year-old Hispanic male with a history of recent orchiectomy for suspected testicular cancer presented to the emergency department with worsening exertional chest pain and dyspnea in the setting of a 2-month history of diffuse myalgias and symmetric polyarthralgias. ... Read more >>

Arthritis Care Res (Hoboken) (Arthritis care & research)
[2021, :]

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Asymmetric organelle positioning during epithelial polarization of C. elegans intestinal cells.

James N Brandt, Laura Voss, Fiona M Rambo, Katelyn Nicholson, Jackson R Thein, Lydia Fairchild, Laurence Seabrook, Danielia Lewis, Lali Guevara-Hernandez, Matthew L White, Luca Sax, Victoria Eichten, Logan Harper, Greg J Hermann,

While the epithelial cell cortex displays profound asymmetries in protein distribution and morphology along the apico-basal axis, the extent to which the cytoplasm is similarly polarized within epithelial cells remains relatively unexplored. We show that cytoplasmic organelles within C. elegans embryonic intestinal cells develop extensive apico-basal polarity at the time ... Read more >>

Dev Biol (Developmental biology)
[2021, :]

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Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol.

Gregory G Schwartz, Michael Szarek, Vera A Bittner, Rafael Diaz, Shaun G Goodman, J Wouter Jukema, Ulf Landmesser, Patricio López-Jaramillo, Garen Manvelian, Robert Pordy, Michel Scemama, Peter R Sinnaeve, Harvey D White, Ph Gabriel Steg, ,

<h4>Background</h4>Guidelines recommend nonstatin lipid-lowering agents in patients at very high risk for major adverse cardiovascular events (MACE) if low-density lipoprotein cholesterol (LDL-C) remains ≥70 mg/dL on maximum tolerated statin treatment. It is uncertain if this approach benefits patients with LDL-C near 70 mg/dL. Lipoprotein(a) levels may influence residual risk.<h4>Objectives</h4>In a post hoc analysis ... Read more >>

J Am Coll Cardiol (Journal of the American College of Cardiology)
[2021, 78(5):421-433]

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A proteomic survival predictor for COVID-19 patients in intensive care

Vadim Demichev, Pinkus Tober-Lau, Tatiana Nazarenko, Simran Kaur Aulakh, Harry Whitwell, Oliver Lemke, Annika Röhl, Anja Freiwald, Mirja Mittermaier, Lukasz Szyrwiel, Daniela Ludwig, Clara Correia-Melo, Lena Lippert, Elisa Helbig, Paula Stubbemann, Nadine Olk, Charlotte Thibeault, Nana-Maria Grüning, Oleg Blyuss, Spyros Vernardis, Matthew White, Christoph Messner, Michael Joannidis, Thomas Sonnweber, Sebastian Klein, Alex Pizzini, Yvonne Wohlfarter, Sabina Sahanic, Richard Hilbe, Benedikt Schaefer, Sonja Wagner, Felix Machleidt, Carmen Garcia, Christoph Ruwwe-Glösenkamp, Tilman Lingscheid, Laure Bosquillon de Jarcy, Miriam Stegemann, Moritz Pfeiffer, Linda Jürgens, Sophy Denker, Daniel Zickler, Claudia Spies, Andreas Edel, Nils Müller, Philipp Enghard, Aleksej Zelezniak, Rosa Bellmann-Weiler, Günter Weiss, Archie Campbell, Caroline Hayward, David Porteous, Riccardo Marioni, Alexander Uhrig, Heinz Zoller, Judith Löffler-Ragg, Markus Keller, Ivan Tancevski, John Timms, Alexey Zaikin, Stefan Hippenstiel, Michael Ramharter, Holger Müller-Redetzky, Martin Witzenrath, Norbert Suttorp, Kathryn Lilley, Michael Mülleder, Leif Erik Sander, Florian Kurth, Markus Ralser, ,

Global healthcare systems are challenged by the COVID-19 pandemic. There is a need to optimize allocation of treatment and resources in intensive care, as clinically established risk assessments such as SOFA and APACHE II scores show only limited performance for predicting the survival of severely ill COVID-19 patients. Comprehensively capturing ... Read more >>

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Effect of Sotagliflozin on Total Hospitalizations in Patients With Type 2 Diabetes and Worsening Heart Failure : A Randomized Trial.

Michael Szarek, Deepak L Bhatt, Ph Gabriel Steg, Christopher P Cannon, Lawrence A Leiter, Darren K McGuire, Julia B Lewis, Matthew C Riddle, Adriaan A Voors, Marco Metra, Lars H Lund, Michel Komajda, Jeffrey M Testani, Christopher S Wilcox, Piotr Ponikowski, Renato D Lopes, Phillip Banks, Eshetu Tesfaye, Justin A Ezekowitz, Subodh Verma, Bertram Pitt, ,

<h4>Background</h4>In the SOLOIST-WHF (Effect of Sotagliflozin on Cardiovascular Events in Patients With Type 2 Diabetes Post Worsening Heart Failure) trial, sotagliflozin, a sodium-glucose cotransporter-1 and sodium-glucose cotransporter-2 inhibitor, reduced total occurrences of cardiovascular deaths, hospitalizations for heart failure, and urgent visits for heart failure relative to placebo by 33%.<h4>Objective</h4>To determine ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2021, 174(8):1065-1072]

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Peripheral neuropathy linked mRNA export factor GANP reshapes gene regulation in human motor neurons

Rosa Woldegebriel, Jouni Kvist, Matthew White, Matilda Sinkko, Satu Hänninen, Markus Sainio, Rubén Torregrosa-Munumer, Sandra Harjuhaahto, Nadine Huber, Sanna-Kaisa Herukka, Annakaisa Haapasalo, Olli Carpen, Andrew Bassett, Emil Ylikallio, Jemeen Sreedharan, Henna Tyynismaa,

<h4>SUMMARY</h4> Loss-of-function of the mRNA export protein GANP ( MCM3AP gene) cause early-onset sensorimotor neuropathy, characterised by axonal degeneration in long peripheral nerves. GANP functions as a scaffold at nuclear pore complexes, contributing to selective nuclear export of mRNAs. Here, we aimed to identify motor neuron specific transcripts that are ... Read more >>

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MRI-guided histology of TDP-43 knock-in mice implicates parvalbumin interneuron loss, impaired neurogenesis and aberrant neurodevelopment in amyotrophic lateral sclerosis-frontotemporal dementia.

Ziqiang Lin, Eugene Kim, Mohi Ahmed, Gang Han, Camilla Simmons, Yushi Redhead, Jack Bartlett, Luis Emiliano Pena Altamira, Isobel Callaghan, Matthew A White, Nisha Singh, Stephen Sawiak, Tara Spires-Jones, Anthony C Vernon, Michael P Coleman, Jeremy Green, Christopher Henstridge, Jeffrey S Davies, Diana Cash, Jemeen Sreedharan,

Amyotrophic lateral sclerosis and frontotemporal dementia are overlapping diseases in which MRI reveals brain structural changes in advance of symptom onset. Recapitulating these changes in preclinical models would help to improve our understanding of the molecular causes underlying regionally selective brain atrophy in early disease. We therefore investigated the translational ... Read more >>

Brain Commun (Brain communications)
[2021, 3(2):fcab114]

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Exploring the process of information sharing in an adult intensive care unit: an ethnographic study.

Emily M Boltey, Nathan Wright, Elizabeth A Mosley, Matthew R White, Theodore J Iwashyna, Milisa Manojlovich, Deena Kelly Costa,

Information sharing, a component of patient and family engagement (PFE), is an important process that may contribute to intensive care unit (ICU) quality of care. Yet, virtually no studies explore how the process of information sharing unfolds in the ICU from the interprofessional team and family member perspectives. To better ... Read more >>

J Interprof Care (Journal of interprofessional care)
[2021, :1-8]

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Characterization of higher harmonic modes in Fabry-Pérot microcavity organic light emitting diodes.

Ekraj Dahal, David Allemeier, Benjamin Isenhart, Karen Cianciulli, Matthew S White,

Encasing an OLED between two planar metallic electrodes creates a Fabry-Pérot microcavity, resulting in significant narrowing of the emission bandwidth. The emission from such microcavity OLEDs depends on the overlap of the resonant cavity modes and the comparatively broadband electroluminescence spectrum of the organic molecular emitter. Varying the thickness of ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):8456]

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Single-Component Organic Solar Cells Based on Intramolecular Charge Transfer Photoabsorption.

Ken-Ichi Nakayama, Tatsuya Okura, Yuki Okuda, Jun Matsui, Akito Masuhara, Tsukasa Yoshida, Matthew Schuette White, Cigdem Yumusak, Phillip Stadler, Markus Scharber, Niyazi Serdar Sariciftci,

Conjugated donor-acceptor molecules with intramolecular charge transfer absorption are employed for single-component organic solar cells. Among the five types of donor-acceptor molecules, the strong push-pull structure of DTDCPB resulted in solar cells with high <i>J</i><sub>SC</sub>, an internal quantum efficiency exceeding 20%, and high <i>V</i><sub>OC</sub> exceeding 1 V with little photon ... Read more >>

Materials (Basel) (Materials (Basel, Switzerland))
[2021, 14(5):]

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Development of a convolutional neural network to differentiate among the etiology of similar appearing pathological B lines on lung ultrasound: a deep learning study.

Robert Arntfield, Blake VanBerlo, Thamer Alaifan, Nathan Phelps, Matthew White, Rushil Chaudhary, Jordan Ho, Derek Wu,

<h4>Objectives</h4>Lung ultrasound (LUS) is a portable, low-cost respiratory imaging tool but is challenged by user dependence and lack of diagnostic specificity. It is unknown whether the advantages of LUS implementation could be paired with deep learning (DL) techniques to match or exceed human-level, diagnostic specificity among similar appearing, pathological LUS ... Read more >>

BMJ Open (BMJ open)
[2021, 11(3):e045120]

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Inhibiting glycogen synthase kinase 3 suppresses TDP-43-mediated neurotoxicity in a caspase-dependant manner

Matthew White, Francesca Massenzio, Xingli Li, Michael Coleman, Sami Barmada, Jemeen Sreedharan,

Amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD) is a progressive and ultimately fatal disease spectrum characterised by 43-kDa TAR DNA-binding protein (TDP-43) pathology. Current disease modifying drugs have modest effects and novel therapies are sorely needed. We previously showed that deletion of glycogen synthase kinase-3 (GSK3) suppresses TDP-43-mediated motor neuron degeneration in ... Read more >>

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Protection against oxaliplatin-induced mechanical and thermal hypersensitivity in Sarm1-/- mice.

Stacey Anne Gould, Matthew White, Anna L Wilbrey, Erzsébet Pór, Michael Philip Coleman, Robert Adalbert,

Chemotherapy-induced peripheral neuropathy (CIPN) is a common dose-limiting side effect of cancer treatment, often associated with degeneration of sensory axons or their terminal regions. Presence of the slow Wallerian degeneration protein (WLD<sup>S</sup>), or genetic deletion of sterile alpha and TIR motif containing protein 1 (SARM1), which strongly protect axons from ... Read more >>

Exp Neurol (Experimental neurology)
[2021, 338:113607]

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AusTraits – a curated plant trait database for the Australian flora

Daniel Falster, Rachael Gallagher, Elizabeth Wenk, Ian Wright, Dony Indiarto, Caitlan Baxter, Samuel Andrew, James Lawson, Stuart Allen, Anne Fuchs, Mark Adams, Collin Ahrens, Matthew Alfonzetti, Tara Angevin, Owen Atkin, Tony Auld, Andrew Baker, Anthony Bean, Chris Blackman, Keith Bloomfield, David Bowman, Jason Bragg, Timothy Brodribb, Genevieve Buckton, Geoff Burrows, Elizabeth Caldwell, James Camac, Raymond Carpenter, Jane Catford, Gregory Cawthray, Lucas Cernusak, Gregory Chandler, Alex Chapman, David Cheal, Alexander Cheesman, Si-Chong Chen, Brendan Choat, Brook Clinton, Peta Clode, Helen Coleman, William Cornwell, Meredith Cosgrove, Michael Crisp, Erika Cross, Kristine Crous, Saul Cunningham, Ellen Curtis, Matthew Daws, Jane DeGabriel, Matthew Denton, Ning Dong, Honglang Duan, David Duncan, Richard Duncan, Marco Duretto, John Dwyer, Cheryl Edwards, Manuel Esperon-Rodriguez, John Evans, Susan Everingham, Jennifer Firn, Carlos Roberto Fonseca, Ben French, Doug Frood, Jennifer Funk, Sonya Geange, Oula Ghannoum, Sean Gleason, Carl Gosper, Emma Gray, Philip Groom, Caroline Gross, Greg Guerin, Lydia Guja, Amy Hahs, Matthew Tom Harrison, Patrick Hayes, Martin Henery, Dieter Hochuli, Jocelyn Howell, Guomin Huang, Lesley Hughes, John Huisman, Jugoslav Ilic, Ashika Jagdish, Daniel Jin, Gregory Jordan, Enrique Jurado, Sabine Kasel, Jürgen Kellermann, Michele Kohout, Robert Kooyman, Martyna Kotowska, Hao Ran Lai, Etienne Laliberté, Hans Lambers, Byron Lamont, Robert Lanfear, Frank van Langevelde, Daniel Laughlin, Bree-Anne Laugier-Kitchener, Caroline Lehmann, Andrea Leigh, Michelle Leishman, Tanja Lenz, Brendan Lepschi, James Lewis, Felix Lim, Udayangani Liu, Janice Lord, Christopher Lusk, Cate Macinnis-Ng, Hannah McPherson, Anthony Manea, Margaret Mayfield, James McCarthy, Trevor Meers, Marlien van der Merwe, Daniel Metcalfe, Per Milberg, Karel Mokany, Angela Moles, Ben Moore, Nicholas Moore, John Morgan, William Morris, Annette Muir, Samantha Munroe, Áine Nicholson, Dean Nicolle, Adrienne Nicotra, Ülo Niinemets, Tom North, Andrew O’Reilly-Nugent, Odhran O’Sullivan, Brad Oberle, Yusuke Onoda, Mark Ooi, Colin Osborne, Grazyna Paczkowska, Burak Pekin, Caio Guilherme Pereira, Catherine Pickering, Melinda Pickup, Laura Pollock, Pieter Poot, Jeff Powell, Sally Power, Iain Colin Prentice, Lynda Prior, Suzanne Prober, Jennifer Read, Victoria Reynolds, Anna Richards, Ben Richardson, Michael Roderick, Julieta Rosell, Maurizio Rossetto, Barbara Rye, Paul Rymer, Michael Sams, Gordon Sanson, Susanne Schmidt, Ernst-Detlef Schulze, Kerrie Sendall, Steve Sinclair, Benjamin Smith, Renee Smith, Fiona Soper, Ben Sparrow, Rachel Standish, Timothy Staples, Guy Taseski, Freya Thomas, David Tissue, Mark Tjoelker, David Yue Phin Tng, Kyle Tomlinson, Neil Turner, Erik Veneklaas, Susanna Venn, Peter Vesk, Carolyn Vlasveld, Maria Vorontsova, Charles Warren, Lasantha Weerasinghe, Mark Westoby, Matthew White, Nicholas Williams, Jarrah Wills, Peter Wilson, Colin Yates, Amy Zanne, Kasia Ziemińska,

We introduce the AusTraits database - a compilation of measurements of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 375 traits across 29230 taxa from field campaigns, published literature, taxonomic monographs, and individual taxa descriptions. Traits vary in scope from physiological measures of performance ... Read more >>

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Evaluating survival in subjects with astrocytic brain tumors by dynamic susceptibility-weighted perfusion MR imaging.

Matthew L White, Yan Zhang, Syed A Jaffar Kazmi, Michele Aizenberg, Nicole Shonka, Fang Yu, Adams Kusi Appiah,

<h4>Purpose</h4>Studies have evaluated the application of perfusion MR for predicting survival in patients with astrocytic brain tumors, but few of them statistically adjust their results to reflect the impact of the variability of treatment administered in the patients. Our aim was to analyze the association between the perfusion values and ... Read more >>

PLoS One (PloS one)
[2021, 16(1):e0244275]

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Introducing 'holistic psychology' for life qualities: A theoretical model for consideration.

Huy P Phan, Bing H Ngu, Matthew O White,

<i>Positive psychology</i> has attracted extensive interests from educators, researchers, and organizations. Many would recognize the work of Martin Seligman (e.g., Seligman, 2010) and Mihaly Csikszentmihalyi (e.g.,Csíkszentmihályi, 2014b). In its summarized form, positive psychology is concerned with a person's state of flourishing, his/her perceived sense of resilience and inner virtues, and ... Read more >>

Heliyon (Heliyon)
[2021, 7(1):e05843]

Cited: 2 times

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Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study.

David Adams, Michael Polydefkis, Alejandra González-Duarte, Jonas Wixner, Arnt V Kristen, Hartmut H Schmidt, John L Berk, Inés Asunción Losada López, Angela Dispenzieri, Dianna Quan, Isabel M Conceição, Michel S Slama, Julian D Gillmore, Theodoros Kyriakides, Senda Ajroud-Driss, Márcia Waddington-Cruz, Michelle M Mezei, Violaine Planté-Bordeneuve, Shahram Attarian, Elizabeth Mauricio, Thomas H Brannagan, Mitsuharu Ueda, Emre Aldinc, Jing Jing Wang, Matthew T White, John Vest, Erhan Berber, Marianne T Sweetser, Teresa Coelho, ,

<h4>Background</h4>Hereditary transthyretin-mediated amyloidosis is a rare, inherited, progressive disease caused by mutations in the transthyretin (TTR) gene. We assessed the safety and efficacy of long-term treatment with patisiran, an RNA interference therapeutic that inhibits TTR production, in patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy.<h4>Methods</h4>This multicentre, open-label extension (OLE) trial enrolled ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2021, 20(1):49-59]

Cited: 5 times

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Coexistence of perseveration and apathy in the TDP-43Q331K knock-in mouse model of ALS-FTD.

Eosu Kim, Matthew A White, Benjamin U Phillips, Laura Lopez-Cruz, Hyunjeong Kim, Christopher J Heath, Jong Eun Lee, Lisa M Saksida, Jemeen Sreedharan, Timothy J Bussey,

Perseveration and apathy are two of the most common behavioural and psychological symptoms of dementia (BPSDs) in amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD). Availability of a validated and behaviourally characterised animal model is crucial for translational research into BPSD in the FTD context. We behaviourally evaluated the male TDP-43<sup>Q331K</sup> mouse, an ... Read more >>

Transl Psychiatry (Translational psychiatry)
[2020, 10(1):377]

Cited: 1 time

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Effects of Interval-Training Exercise on People Who Have Had Persistent Post-Concussive Symptoms for Less Than One Year: A Pilot Study.

Yi-Ning Wu, Caroline Stark, Jessica Gravel, Matthew White, Josh Avery, Terrie Enis, Robert C Cantu,

This study is to examine the effects of a 12-session moderate intensity-interval-training program with blood flow restriction (BFR) and body cooling (BC) on people who have had persistent post-concussive symptoms (PPCS) for <1 year. A single-blind randomized controlled trial of interval-training exercise with BFR and BC was conducted. Twenty-five adults ... Read more >>

J Neurotrauma (Journal of neurotrauma)
[2021, 38(5):573-581]

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Arachnoid Cysts

Matthew L. White, Joe M Das,

Arachnoid cysts are common incidentally found lesions in the brain when imaging is being performed.[1][2][3] The majority of arachnoid cysts are in the anterior/middle cranial fossa or in a retrocerebellar location. The etiology of most arachnoid cysts is unknown, but very likely the majority occur during development. These cysts occur as ... Read more >>

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Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure.

Deepak L Bhatt, Michael Szarek, P Gabriel Steg, Christopher P Cannon, Lawrence A Leiter, Darren K McGuire, Julia B Lewis, Matthew C Riddle, Adriaan A Voors, Marco Metra, Lars H Lund, Michel Komajda, Jeffrey M Testani, Christopher S Wilcox, Piotr Ponikowski, Renato D Lopes, Subodh Verma, Pablo Lapuerta, Bertram Pitt, ,

<h4>Background</h4>Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure or death from cardiovascular causes among patients with stable heart failure. However, the safety and efficacy of SGLT2 inhibitors when initiated soon after an episode of decompensated heart failure are unknown.<h4>Methods</h4>We performed a multicenter, double-blind trial in ... Read more >>

N Engl J Med (The New England journal of medicine)
[2021, 384(2):117-128]

Cited: 101 times

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Stable knockout of lanthionine synthase C-like protein-1 (LanCL1) from HeLa cells indicates a role for LanCL1 in redox regulation of deubiquitinating enzymes.

Aaron Downey, Melissa Olcott, Daniel Spector, Kayla Bird, Amanda Ter Doest, Zachary Pierce, Evan Quach, Sawyer Sparks, Christa Super, Jefferey Naifeh, Andrea Powers, Matthew White, Kenneth Hensley,

Lanthionine synthase C-like protein-1 (LanCL1) is a glutathione (GSH)-binding protein of uncertain function, widely expressed in mammalian cells. Recent data suggests that LanCL1 has glutathione S-transferase (GST)-like activity, while other reports claim that LanCL1 suppresses mitogen-activated kinase (MAPK) phosphorylation. In the present study, recombinant human LanCL1 had less than 10% ... Read more >>

Free Radic Biol Med (Free radical biology & medicine)
[2020, 161:115-124]

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Spatial conservation action planning in heterogeneous landscapes

Jim Thomson, Tracey J Regan, Tracey Hollings, Nevil Amos, William L Geary, David Parkes, Cindy E Hauser, Matthew White,

A key challenge in conservation is the efficient allocation of limited resources to maximise benefits for biodiversity. Decision-support tools that account for landscape heterogeneity are needed to identify spatially-explicit actions that will achieve the greatest biodiversity benefits with available resources. We developed a raster-based, landscape-scale, spatial conservation action planning tool ... Read more >>

Biol Conserv (Biological conservation.)
[2020, 250:Not Available]

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A biomechanical comparison of powered robotic exoskeleton gait with normal and slow walking: An investigation with able-bodied individuals.

Stephen Clive Hayes, Matthew White, Hollie Samantha Forbes White, Natalie Vanicek,

<h4>Background</h4>Overground lower-limb robotic exoskeletons are assistive devices used to facilitate ambulation and gait rehabilitation. Our understanding of how closely they resemble comfortable and slow walking is limited. This information is important to maximise the effects of gait rehabilitation. The aim was to compare the 3D gait parameters of able-bodied individuals ... Read more >>

Clin Biomech (Bristol, Avon) (Clinical biomechanics (Bristol, Avon))
[2020, 80:105133]

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