Full Text Journal Articles by
Author Matthew D Robson

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Magnetic resonance phase contrast velocity mapping for flow quantification in irregular heart rhythms using radial k-space ultrashort echo time imaging.

Michaela M Hell, Jane M Francis, Joanna d'Arcy, Matthew D Robson, Stefan Neubauer, Stephan Achenbach, Saul G Myerson,

BACKGROUND:Phase contrast velocity mapping sequences utilising ultrashort echo time (UTE) radial k-space sequences have been used to reduce intravoxel dephasing at high velocities. We evaluated the accuracy of the UTE flow sequence for mitral regurgitation (MR) quantification, including patients with atrial fibrillation. METHODS:Forty patients underwent cardiac MRI for indirect MR ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2020, :]

Cited: 0 times

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Constraints in estimating the proton density fat fraction.

Mark Bydder, Vahid Ghodrati, Yu Gao, Matthew D Robson, Yingli Yang, Peng Hu,

The study evaluates four physically motivated constraints in the estimation of the proton density fat fraction (PDFF). Least squares approaches were developed for constraining the parameters in PDFF quantification based on the physics of magnetic resonance imaging. These were smooth fieldmap, smooth initial phase, nonnegative proton density and moderate R2∗ ... Read more >>

Magn Reson Imaging (Magnetic resonance imaging)
[2020, 66:1-8]

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Navigator-based reacquisition and estimation of motion-corrupted data: Application to multi-echo spin echo for carotid wall MRI.

Robert Frost, Luca Biasiolli, Linqing Li, Katherine Hurst, Mohammad Alkhalil, Robin P Choudhury, Matthew D Robson, Aaron T Hess, Peter Jezzard,

PURPOSE:To assess whether artifacts in multi-slice multi-echo spin echo neck imaging, thought to be caused by brief motion events such as swallowing, can be corrected by reacquiring corrupted central k-space data and estimating the remainder with parallel imaging. METHODS:A single phase-encode line (ky = 0, phase-encode direction anteroposterior) navigator echo ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2020, 83(6):2026-2041]

Cited: 1 time

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Non-invasive assessment of portal hypertension by multi-parametric magnetic resonance imaging of the spleen: A proof of concept study.

Christina Levick, Jane Phillips-Hughes, Jane Collier, Rajarshi Banerjee, Jeremy F Cobbold, Lai Mun Wang, Stefan K Piechnik, Matthew D Robson, Stefan Neubauer, Eleanor Barnes, Michael Pavlides,

BACKGROUND AND AIMS:Non-invasive assessment of portal hypertension is an area of unmet need. This proof of concept study aimed to evaluate the diagnostic accuracy of a multi-parametric magnetic resonance technique in the assessment of portal hypertension. Comparison to other non-invasive technologies was a secondary aim. METHODS:T1 and T2* maps through ... Read more >>

PLoS ONE (PloS one)
[2019, 14(8):e0221066]

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Scattering matrix imaging pulse design for real-time respiration and cardiac motion monitoring.

Sven H F Jaeschke, Matthew D Robson, Aaron T Hess,

PURPOSE:The scattering matrix (S-matrix) of a parallel transmit (pTx) coil is sensitive to physiological motion but requires additional monitoring RF pulses to be measured. In this work, we present and evaluate pTx RF pulse designs that simultaneously excite for imaging and measure the S-matrix to generate real-time motion signals without ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2019, 82(6):2169-2177]

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Identification of Myocardial Disarray in Patients With Hypertrophic Cardiomyopathy and Ventricular Arrhythmias.

Rina Ariga, Elizabeth M Tunnicliffe, Sanjay G Manohar, Masliza Mahmod, Betty Raman, Stefan K Piechnik, Jane M Francis, Matthew D Robson, Stefan Neubauer, Hugh Watkins,

BACKGROUND:Myocardial disarray is a likely focus for fatal arrhythmia in hypertrophic cardiomyopathy (HCM). This microstructural abnormality can be inferred by mapping the preferential diffusion of water along cardiac muscle fibers using diffusion tensor cardiac magnetic resonance (DT-CMR) imaging. Fractional anisotropy (FA) quantifies directionality of diffusion in 3 dimensions. The authors ... Read more >>

J. Am. Coll. Cardiol. (Journal of the American College of Cardiology)
[2019, 73(20):2493-2502]

Cited: 1 time

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Magnitude-intrinsic water-fat ambiguity can be resolved with multipeak fat modeling and a multipoint search method.

Alexandre Triay Bagur, Chloe Hutton, Benjamin Irving, Michael L Gyngell, Matthew D Robson, Michael Brady,

PURPOSE:To develop a postprocessing algorithm for multiecho chemical-shift encoded water-fat separation that estimates proton density fat fraction (PDFF) maps over the full dynamic range (0-100%) using multipeak fat modeling and multipoint search optimization. To assess its accuracy, reproducibility, and agreement with state-of-the-art complex-based methods, and to evaluate its robustness to ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2019, 82(1):460-475]

Cited: 1 time

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Measuring inorganic phosphate and intracellular pH in the healthy and hypertrophic cardiomyopathy hearts by in vivo 7T 31P-cardiovascular magnetic resonance spectroscopy.

Ladislav Valkovič, William T Clarke, Albrecht I Schmid, Betty Raman, Jane Ellis, Hugh Watkins, Matthew D Robson, Stefan Neubauer, Christopher T Rodgers,

BACKGROUND:Cardiovascular phosphorus MR spectroscopy (31P-CMRS) is a powerful tool for probing energetics in the human heart, through quantification of phosphocreatine (PCr) to adenosine triphosphate (ATP) ratio. In principle, 31P-CMRS can also measure cardiac intracellular pH (pHi) and the free energy of ATP hydrolysis (ΔGATP). However, these require determination of the ... Read more >>

J Cardiovasc Magn Reson (Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance)
[2019, 21(1):19]

Cited: 2 times

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Feasibility of absolute quantification for 31 P MRS at 7 T.

Lucian A B Purvis, Ladislav Valkovič, Matthew D Robson, Christopher T Rodgers,

PURPOSE:Phosphorus spectroscopy can differentiate among liver disease stages and types. To quantify absolute concentrations of phosphorus metabolites, sensitivity calibration and transmit field ( B1+ ) correction are required. The trend toward ultrahigh fields (7 T) and the use of multichannel RF coils makes this ever more challenging. We investigated the ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2019, 82(1):49-61]

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Automated localization and quality control of the aorta in cine CMR can significantly accelerate processing of the UK Biobank population data.

Luca Biasiolli, Evan Hann, Elena Lukaschuk, Valentina Carapella, Jose M Paiva, Nay Aung, Jennifer J Rayner, Konrad Werys, Kenneth Fung, Henrike Puchta, Mihir M Sanghvi, Niall O Moon, Ross J Thomson, Katharine E Thomas, Matthew D Robson, Vicente Grau, Steffen E Petersen, Stefan Neubauer, Stefan K Piechnik,

INTRODUCTION:Aortic distensibility can be calculated using semi-automated methods to segment the aortic lumen on cine CMR (Cardiovascular Magnetic Resonance) images. However, these methods require visual quality control and manual localization of the region of interest (ROI) of ascending (AA) and proximal descending (PDA) aorta, which limit the analysis in large-scale ... Read more >>

PLoS ONE (PloS one)
[2019, 14(2):e0212272]

Cited: 1 time

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Mapping tissue water T1 in the liver using the MOLLI T1 method in the presence of fat, iron and B0 inhomogeneity.

Ferenc E Mozes, Elizabeth M Tunnicliffe, Ahmad Moolla, Thomas Marjot, Christina K Levick, Michael Pavlides, Matthew D Robson,

Modified Look-Locker inversion recovery (MOLLI) T1 mapping sequences can be useful in cardiac and liver tissue characterization, but determining underlying water T1 is confounded by iron, fat and frequency offsets. This article proposes an algorithm that provides an independent water MOLLI T1 (referred to as on-resonance water T1 ) that ... Read more >>

NMR Biomed (NMR in biomedicine)
[2019, 32(2):e4030]

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T2 mapping MRI technique quantifies carotid plaque lipid, and its depletion after statin initiation, following acute myocardial infarction.

Mohammad Alkhalil, Luca Biasiolli, Naveed Akbar, Francesca Galassi, Joshua T Chai, Matthew D Robson, Robin P Choudhury,

BACKGROUND & AIMS:A recently-validated, highly-sensitive T2 mapping magnetic resonance (MRI) technique accurately quantifies carotid plaque lipid. The aims of this study were to determine: (i) the extent of carotid plaque lipid in patients with acute coronary syndromes (ACS); (ii) the effects of initiation of high-intensity statin on plaque lipid content ... Read more >>

Atherosclerosis (Atherosclerosis)
[2018, 279:100-106]

Cited: 1 time

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Anti-TNF modulation reduces myocardial inflammation and improves cardiovascular function in systemic rheumatic diseases.

Ntobeko A B Ntusi, Jane M Francis, Emily Sever, Alexander Liu, Stefan K Piechnik, Vanessa M Ferreira, Paul M Matthews, Matthew D Robson, Paul B Wordsworth, Stefan Neubauer, Theodoros D Karamitsos,

BACKGROUND:Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are common disorders associated with increased rates of cardiovascular disease (CVD), but the contribution of cytokine-induced inflammation to impaired cardiovascular function in these conditions remains poorly understood. OBJECTIVES:We assessed the effect of anti-TNF therapy on myocardial and vascular function, myocardial ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2018, 270:253-259]

Cited: 0 times

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The relationship of perivascular adipose tissue and atherosclerosis in the aorta and carotid arteries, determined by magnetic resonance imaging.

Mohammad Alkhalil, Evan Edmond, Laurienne Edgar, Janet E Digby, Omar Omar, Matthew D Robson, Robin P Choudhury,

BACKGROUND AND AIMS:Imaging studies have relied on the 'overall' volumetric quantification of perivascular adipose tissue. We sought to assess the relationship of circumferential distribution between perivascular adipose tissue and adjacent wall thickness of carotid and aortic arteries using dedicated magnetic resonance imaging sequences. METHODS:Vessel wall and perivascular adipose tissue were ... Read more >>

Diab Vasc Dis Res (Diabetes & vascular disease research)
[2018, 15(4):286-293]

Cited: 1 time

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Cardiac gating using scattering of an 8-channel parallel transmit coil at 7T.

Sven H F Jaeschke, Matthew D Robson, Aaron T Hess,

PURPOSE:To establish a cardiac signal from scattering matrix or scattering coefficient measurements made on a 7T 8-channel parallel transmit (pTx) system, and to evaluate its use for cardiac gating. METHODS:Measurements of the scattering matrix and scattering coefficients were acquired using a monitoring pulse sequence and during a standard cine acquisition, ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2018, 80(2):633-640]

Cited: 2 times

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Using a whole-body 31P birdcage transmit coil and 16-element receive array for human cardiac metabolic imaging at 7T.

Ladislav Valkovič, Iulius Dragonu, Salam Almujayyaz, Alex Batzakis, Liam A J Young, Lucian A B Purvis, William T Clarke, Tobias Wichmann, Titus Lanz, Stefan Neubauer, Matthew D Robson, Dennis W J Klomp, Christopher T Rodgers,

Cardiac phosphorus magnetic resonance spectroscopy (31P-MRS) provides unique insight into the mechanisms of heart failure. Yet, clinical applications have been hindered by the restricted sensitivity of the surface radiofrequency-coils normally used. These permit the analysis of spectra only from the interventricular septum, or large volumes of myocardium, which may not ... Read more >>

PLoS ONE (PloS one)
[2017, 12(10):e0187153]

Cited: 4 times

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OXSA: An open-source magnetic resonance spectroscopy analysis toolbox in MATLAB.

Lucian A B Purvis, William T Clarke, Luca Biasiolli, Ladislav Valkovič, Matthew D Robson, Christopher T Rodgers,

In vivo magnetic resonance spectroscopy provides insight into metabolism in the human body. New acquisition protocols are often proposed to improve the quality or efficiency of data collection. Processing pipelines must also be developed to use these data optimally. Current fitting software is either targeted at general spectroscopy fitting, or ... Read more >>

PLoS ONE (PloS one)
[2017, 12(9):e0185356]

Cited: 8 times

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Highly trabeculated structure of the human endocardium underlies asymmetrical response to low-energy monophasic shocks.

Adam Connolly, Matthew D Robson, Jürgen Schneider, Rebecca Burton, Gernot Plank, Martin J Bishop,

Novel low-energy defibrillation therapies are thought to be driven by virtual-electrodes (VEs), due to the interaction of applied monophasic electric shocks with fine-scale anatomical structures within the heart. Significant inter-species differences in the cardiac (micro)-anatomy exist, however, particularly with respect to the degree of endocardial trabeculations, which may underlie important ... Read more >>

Chaos (Chaos (Woodbury, N.Y.))
[2017, 27(9):093913]

Cited: 1 time

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CMR Native T1 Mapping Allows Differentiation of Reversible Versus Irreversible Myocardial Damage in ST-Segment-Elevation Myocardial Infarction: An OxAMI Study (Oxford Acute Myocardial Infarction).

Dan Liu, Alessandra Borlotti, Dafne Viliani, Michael Jerosch-Herold, Mohammad Alkhalil, Giovanni Luigi De Maria, Gregor Fahrni, Sam Dawkins, Rohan Wijesurendra, Jane Francis, Vanessa Ferreira, Stefan Piechnik, Matthew D Robson, Adrian Banning, Robin Choudhury, Stefan Neubauer, Keith Channon, Rajesh Kharbanda, Erica Dall'Armellina,

BACKGROUND:CMR T1 mapping is a quantitative imaging technique allowing the assessment of myocardial injury early after ST-segment-elevation myocardial infarction. We sought to investigate the ability of acute native T1 mapping to differentiate reversible and irreversible myocardial injury and its predictive value for left ventricular remodeling. METHODS AND RESULTS:Sixty ST-segment-elevation myocardial ... Read more >>

Circ Cardiovasc Imaging (Circulation. Cardiovascular imaging)
[2017, 10(8):]

Cited: 18 times

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Diaphragm position can be accurately estimated from the scattering of a parallel transmit RF coil at 7 T.

Aaron T Hess, Elizabeth M Tunnicliffe, Christopher T Rodgers, Matthew D Robson,

PURPOSE:To evaluate the use of radiofrequency scattering of a parallel transmit coil to track diaphragm motion. METHODS:Measurements made during radiofrequency excitation on an 8-channel parallel transmit coil by the directional couplers of the radiofrequency safety monitor were combined and converted into diaphragm position. A 30-s subject-specific calibration with an MRI ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2018, 79(4):2164-2169]

Cited: 5 times

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Multiparametric magnetic resonance imaging for the assessment of non-alcoholic fatty liver disease severity.

Michael Pavlides, Rajarshi Banerjee, Elizabeth M Tunnicliffe, Catherine Kelly, Jane Collier, Lai Mun Wang, Kenneth A Fleming, Jeremy F Cobbold, Matthew D Robson, Stefan Neubauer, Eleanor Barnes,

The diagnosis of non-alcoholic steatohepatitis and fibrosis staging are central to non-alcoholic fatty liver disease assessment. We evaluated multiparametric magnetic resonance in the assessment of non-alcoholic steatohepatitis and fibrosis using histology as standard in non-alcoholic fatty liver disease.Seventy-one patients with suspected non-alcoholic fatty liver disease were recruited within 1 month of ... Read more >>

Liver Int. (Liver international : official journal of the International Association for the Study of the Liver)
[2017, 37(7):1065-1073]

Cited: 21 times

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Phosphodiester content measured in human liver by in vivo 31 P MR spectroscopy at 7 tesla.

Lucian A B Purvis, William T Clarke, Ladislav Valkovič, Christina Levick, Michael Pavlides, Eleanor Barnes, Jeremy F Cobbold, Matthew D Robson, Christopher T Rodgers,

Phosphorus (31 P) metabolites are emerging liver disease biomarkers. Of particular interest are phosphomonoester and phosphodiester (PDE) "peaks" that comprise multiple overlapping resonances in 31 P spectra. This study investigates the effect of improved spectral resolution at 7 Tesla (T) on quantifying hepatic metabolites in cirrhosis.Five volunteers were scanned to ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2017, 78(6):2095-2105]

Cited: 6 times

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Adiabatic excitation for 31 P MR spectroscopy in the human heart at 7 T: A feasibility study.

Ladislav Valkovič, William T Clarke, Lucian A B Purvis, Benoit Schaller, Matthew D Robson, Christopher T Rodgers,

PURPOSE:Phosphorus magnetic resonance spectroscopy (31 P-MRS) provides a unique tool for assessing cardiac energy metabolism, often quantified using the phosphocreatine (PCr)/adenosine triphosphate (ATP) ratio. Surface coils are typically used for excitation for 31 P-MRS, but they create an inhomogeneous excitation field across the myocardium, producing undesirable, spatially varying partial saturation. ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2017, 78(5):1667-1673]

Cited: 3 times

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Reply to: "Multiparametric magnetic resonance imaging to predict clinical outcomes in patients with chronic liver disease: A cautionary note on a promising technique".

Michael Pavlides, Rajarshi Banerjee, Catherine J Kelly, Matthew D Robson, Stefan Neubauer, Eleanor Barnes,

J. Hepatol. (Journal of hepatology)
[2017, 66(2):457-458]

Cited: 0 times

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A look-locker acquisition scheme for quantitative myocardial perfusion imaging with FAIR arterial spin labeling in humans at 3 tesla.

Graeme A Keith, Christopher T Rodgers, Michael A Chappell, Matthew D Robson,

A novel method for quantitative measurement of myocardial blood flow (MBF) using arterial spin labeling (ASL) in a single breath-hold is presented, evaluated by simulations, phantom studies and in vivo studies and tested for reproducibility and variability.A flow-sensitive alternating inversion recovery (FAIR) ASL method with Look-Locker readout (LL-FAIR-ASL) was implemented ... Read more >>

Magn Reson Med (Magnetic resonance in medicine)
[2017, 78(2):541-549]

Cited: 3 times

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