Full Text Journal Articles by
Author Matteo Gastaldi

Advertisement

Find full text journal articles






Isolated bulbar palsy after SARS-CoV-2 infection.

Massimiliano Todisco, Enrico Alfonsi, Sebastiano Arceri, Giulia Bertino, Carlo Robotti, Michele Albergati, Matteo Gastaldi, Cristina Tassorelli, Giuseppe Cosentino,

Lancet Neurol (The Lancet. Neurology)
[2021, 20(3):169-170]

Cited: 0 times

View full text PDF listing >>



NfL levels predominantly increase at disease onset in MOG-Abs-associated disorders.

Mariotto Sara, Gastaldi Matteo, Grazian Luisa, Mancinelli Chiara, Capra Ruggero, Marignier Romain, Alberti Daniela, Zanzoni Serena, Schanda Kathrin, Franciotta Diego, Calabria Francesca, Monaco Salvatore, Reindl Markus, Ferrari Sergio, Gajofatto Alberto,

The unpredictable course and uncertain impact of relapses make treatment strategies of anti-myelin oligodendrocyte glycoprotein antibodies associated disorders (MOGAD) challenging. We analysed neurofilament light chain levels (NfL) in onset and follow-up sera of 18 patients with MOGAD to clarify the timing of axonal damage. In comparison with disease onset values ... Read more >>

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2021, 50:102833]

Cited: 0 times

View full text PDF listing >>



Advertisement

Adoptive Transfer of JC Virus-Specific T Lymphocytes for the Treatment of Progressive Multifocal Leukoencephalopathy.

Giulia Berzero, Sabrina Basso, Luca Stoppini, Andrea Palermo, Anna Pichiecchio, Matteo Paoletti, Federica Lucev, Simonetta Gerevini, Andrea Rossi, Elisa Vegezzi, Luca Diamanti, Paola Bini, Matteo Gastaldi, Serena Delbue, Cesare Perotti, Elena Seminari, Maura Faraci, Mario Luppi, Fausto Baldanti, Marco Zecca, Enrico Marchioni, Patrizia Comoli,

<h4>Objective</h4>Progressive multifocal leukoencephalopathy (PML) is still burdened by high mortality in a subset of patients, such as those affected by hematological malignancies. The aim of this study was to analyze the safety and carry out preliminary evaluation of the efficacy of polyomavirus JC (JCPyV)-specific T cell therapy in a cohort ... Read more >>

Ann Neurol (Annals of neurology)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Comparison of N-methyl-D-aspartate receptor antibody assays using live or fixed substrates.

Anaïs Thouin, Matteo Gastaldi, Mark Woodhall, Leslie Jacobson, Angela Vincent,

The diagnostic criteria for N-methyl-D-aspartate receptor antibody (NMDAR-Ab) encephalitis require the presence of CSF antibodies against the NMDAR, whereas serum antibodies are considered specific only if accompanied by CSF antibodies. Current assays include in-house immunochemistry (IHC), or cell-based assays (CBA) which use live (L-CBA) or fixed cells (F-CBA), and commercially ... Read more >>

J Neurol (Journal of neurology)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Safety of disease-modifying treatments in SARS-CoV-2 antibody-positive multiple sclerosis patients.

Giulia Mallucci, Antonio Zito, Fausto Baldanti, Matteo Gastaldi, Beatrice Dal Fabbro, Diego Franciotta, Roberto Bergamaschi,

<h4>Background</h4>Coronavirus disease 2019 (COVID-19) raises particular concerns for people with multiple sclerosis (PwMS) on disease-modifying treatments (DMTs), and for physicians caring for them. The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on PwMS receiving DMTs that inhibit immune cell trafficking, such as natalizumab (NTZ) and fingolimod (FTY), ... Read more >>

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2021, 49:102754]

Cited: 0 times

View full text PDF listing >>



New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab.

Inmaculada Toboso, Amalia Tejeda-Velarde, Roberto Alvarez-Lafuente, Rafael Arroyo, Harald Hegen, Florian Deisenhammer, Susana Sainz de la Maza, José C Alvarez-Cermeño, Guillermo Izquierdo, Dolores Paramo, Pedro Oliva, Bonaventura Casanova, Eduardo Agüera-Morales, Diego Franciotta, Matteo Gastaldi, Oscar Fernández, Patricia Urbaneja, José M Garcia-Dominguez, Fernando Romero, Alicia Laroni, Antonio Uccelli, Angel Perez-Sempere, Albert Saiz, Yolanda Blanco, Daniela Galimberti, Elio Scarpini, Carmen Espejo, Xavier Montalban, Ludwig Rasche, Friedemann Paul, Inés González, Elena Álvarez, Cristina Ramo, Ana B Caminero, Yolanda Aladro, Carmen Calles, Pablo Eguía, Antonio Belenguer-Benavides, Lluis Ramió-Torrentà, Ester Quintana, José E Martínez-Rodríguez, Agustín Oterino, Carlos López de Silanes, Luis I Casanova, Lamberto Landete, Jette Frederiksen, Gabriel Bsteh, Patricia Mulero, Manuel Comabella, Miguel A Hernández, Mercedes Espiño, José M Prieto, Domingo Pérez, María Otano, Francisco Padilla, Juan A García-Merino, Laura Navarro, Alfonso Muriel, Lucienne Costa Frossard, Luisa M Villar,

<b>Overview:</b> We assessed the role of age and disease activity as new factors contributing to establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis patients treated with natalizumab in 36 University Hospitals in Europe. We performed the study in 1,307 multiple sclerosis patients (70.8% anti-John Cunninghan virus positive antibodies) ... Read more >>

Front Neurol (Frontiers in neurology)
[2020, 11:579438]

Cited: 0 times

View full text PDF listing >>



Levodopa-responsive progressive encephalomyelitis with rigidity and myoclonus associated with glycine receptor antibodies.

Andrea Sturchio, Matteo Gastaldi, Lucia Princiotta Cariddi, Daniela Biacchi, Alberto J Espay, Diego Franciotta, Maurizio Versino, Marco Mauri,

Parkinsonism Relat Disord (Parkinsonism & related disorders)
[2021, 82:7-9]

Cited: 0 times

View full text PDF listing >>



AQP4 autoantibodies in patients with idiopathic normal pressure hydrocephalus.

Matteo Gastaldi, Massimiliano Todisco, Giorgia Carlin, Silvia Scaranzin, Elisabetta Zardini, Brigida Minafra, Roberta Zangaglia, Anna Pichiecchio, Markus Reindl, Sven Jarius, Claudio Pacchetti, Diego Franciotta,

Idiopathic normal pressure hydrocephalus (iNPH) is a common neurological disorder with unknown etiology. A selective depletion of aquaporin 4 (AQP4) has been shown in iNPH patients. We collected serum and cerebrospinal fluid (CSF) from 43 iNPH patients and 35 with other neurodegenerative conditions, and serum from 43 healthy subjects. All ... Read more >>

J Neuroimmunol (Journal of neuroimmunology)
[2020, 349:577407]

Cited: 0 times

View full text PDF listing >>



Inter-center agreement in the interpretation of oligoclonal bands.

Sara Mariotto, Diana Ferraro, Fabio Soldani, Daniela Alberti, Roberta Bedin, Patrizia Sola, Matteo Gastaldi, Diego Franciotta, Sergio Ferrari,

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Kappa Index Versus CSF Oligoclonal Bands in Predicting Multiple Sclerosis and Infectious/Inflammatory CNS Disorders.

Diana Ferraro, Roberta Bedin, Patrizia Natali, Diego Franciotta, Krzysztof Smolik, Mario Santangelo, Paolo Immovilli, Valentina Camera, Francesca Vitetta, Matteo Gastaldi, Tommaso Trenti, Stefano Meletti, Patrizia Sola,

<h4>Background</h4>Cerebrospinal fluid (CSF) kappa free light chains (KFLC) are gaining increasing interest as markers of intrathecal immunoglobulin synthesis. The main aim of this study was to assess the diagnostic accuracy (AUC) of the kappa index (CSF/serum KFLC divided by the CSF/serum albumin ratio) compared to CSF oligoclonal IgG bands (OCB) ... Read more >>

Diagnostics (Basel) (Diagnostics (Basel, Switzerland))
[2020, 10(10):]

Cited: 0 times

View full text PDF listing >>



Primary central nervous system lymphoma mimicking autoimmune encephalitis: the role of autoantibody testing.

Eleonora Rigoni, Lisa Farina, Paola Bini, Patrizia Morbini, Diego Franciotta, Matteo Gastaldi,

Neurol Sci (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2021, 42(3):1193-1196]

Cited: 0 times

View full text PDF listing >>



COVID-19 and Guillain-Barré Syndrome: A Case Report and Review of Literature.

Antonio Zito, Enrico Alfonsi, Diego Franciotta, Massimiliano Todisco, Matteo Gastaldi, Matteo Cotta Ramusino, Mauro Ceroni, Alfredo Costa,

During the recent coronavirus disease 2019 (COVID-19) outbreak in Northern Italy, we observed a 57-year-old man developing acute motor-sensory axonal neuropathy, a variant of Guillain-Barré syndrome (GBS), 12 days after severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. Similarly to other bacterial and viral infections, dysregulation of the immune system due to ... Read more >>

Front Neurol (Frontiers in neurology)
[2020, 11:909]

Cited: 5 times

View full text PDF listing >>



Cell-based assays for the detection of MOG antibodies: a comparative study.

Matteo Gastaldi, Silvia Scaranzin, Sven Jarius, Brigitte Wildeman, Elisabetta Zardini, Giulia Mallucci, Eleonora Rigoni, Elisa Vegezzi, Thomas Foiadelli, Salvatore Savasta, Paola Banfi, Maurizio Versino, Luana Benedetti, Giovanni Novi, Margherita Maria Mancardi, Thea Giacomini, Pietro Annovazzi, Damiano Baroncini, Diana Ferraro, Vito Lampasona, Markus Reindl, Patrick Waters, Diego Franciotta,

BACKGROUND:The detection of antibodies to myelin oligodendrocyte glycoprotein (MOG) is fundamental for the identification of MOG antibody-associated disorders (MOGAD), and the differential diagnosis of acquired demyelinating syndromes of the CNS, among which multiple sclerosis (MS). We compared the diagnostic performance of four cell-based assays (CBAs) for their detection. METHODS:Consecutive sera ... Read more >>

J Neurol (Journal of neurology)
[2020, 267(12):3555-3564]

Cited: 1 time

View full text PDF listing >>



Acquisition of human immunodeficiency virus infection in a patient with multiple sclerosis: could these conditions positively influence each other's course?

Ilaria Mainardi, Maria Teresa Ferrò, Matteo Gastaldi, Diego Franciotta, Paola Cinque,

Patients with human immunodeficiency virus (HIV) infection have a decreased risk of developing multiple sclerosis (MS) and MS patients very rarely contract HIV infection. We report on a 35-year-old woman with relapsing-remitting MS, who acquired HIV infection 8 years after MS onset. During 7 years of follow-up without combined antiretroviral therapy (cART), ... Read more >>

J Neurovirol (Journal of neurovirology)
[2020, 26(6):957-960]

Cited: 0 times

View full text PDF listing >>



Seizures and myelin oligodendrocyte glycoprotein (MOG) antibodies: Two paradigmatic cases and a review of the literature.

Thomas Foiadelli, Matteo Gastaldi, Silvia Scaranzin, Diego Franciotta, Salvatore Savasta,

BACKGROUND:Myelin oligodendrocyte glycoprotein (MOG) antibodies (Abs) have been associated with a heterogeneous range of acquired CNS demyelinating disorders. More recently, increasing evidence correlates the presence of such Abs with seizures, occurring in concomitance with CNS demyelinating events, or even as isolated phenomena. In this scenario, the full clinical spectrum of ... Read more >>

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2020, 41:102011]

Cited: 1 time

View full text PDF listing >>



Pediatric optic neuritis and anti MOG antibodies: a cohort of Italian patients.

Thea Giacomini, Thomas Foiadelli, Pietro Annovazzi, Margherita Nosadini, Matteo Gastaldi, Diego Franciotta, Claudio Panarese, Paolo Capris, Paola Camicione, Paola Lanteri, Elisa De Grandis, Giulia Prato, Ramona Cordani, Lino Nobili, Giovanni Morana, Andrea Rossi, Angela Pistorio, Maria Cellerino, Antonio Uccelli, Stefano Sartori, Salvatore Savasta, Maria Margherita Mancardi,

BACKGROUND:recent studies reported that anti myelin oligodendrocyte glycoprotein (MOG) antibody (ab) related optic neuritis (ON) tend to have characteristics that differ from seronegative ones. The aim of our study was to investigate the clinical characteristics of pediatric anti-MOG ON by comparing anti MOG-ab-seropositive and seronegative patients with ON. METHODS:in this ... Read more >>

Mult Scler Relat Disord (Multiple sclerosis and related disorders)
[2019, 39:101917]

Cited: 1 time

View full text PDF listing >>



Antibodies to neurofascin, contactin-1, and contactin-associated protein 1 in CIDP: Clinical relevance of IgG isotype.

Andrea Cortese, Raffaella Lombardi, Chiara Briani, Ilaria Callegari, Luana Benedetti, Fiore Manganelli, Marco Luigetti, Sergio Ferrari, Angelo M Clerici, Girolama Alessandra Marfia, Andrea Rigamonti, Marinella Carpo, Raffaella Fazio, Massimo Corbo, Anna Mazzeo, Fabio Giannini, Giuseppe Cosentino, Elisabetta Zardini, Riccardo Currò, Matteo Gastaldi, Elisa Vegezzi, Enrico Alfonsi, Angela Berardinelli, Ludivine Kouton, Constance Manso, Claudia Giannotta, Pietro Doneddu, Patrizia Dacci, Laura Piccolo, Marta Ruiz, Alessandro Salvalaggio, Chiara De Michelis, Emanuele Spina, Antonietta Topa, Giulia Bisogni, Angela Romano, Sara Mariotto, Giorgia Mataluni, Federica Cerri, Claudia Stancanelli, Mario Sabatelli, Angelo Schenone, Enrico Marchioni, Giuseppe Lauria, Eduardo Nobile-Orazio, Jérôme Devaux, Diego Franciotta,

<h4>Objective</h4>To assess the prevalence and isotypes of anti-nodal/paranodal antibodies to nodal/paranodal proteins in a large chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) cohort, compare clinical features in seronegative vs seropositive patients, and gather evidence of their isotype-specific pathogenic role.<h4>Methods</h4>Antibodies to neurofascin-155 (Nfasc155), neurofascin-140/186 (Nfasc140/186), contactin-1 (CNTN1), and contactin-associated protein 1 (Caspr1) were ... Read more >>

Neurol Neuroimmunol Neuroinflamm (Neurology(R) neuroimmunology & neuroinflammation)
[2020, 7(1):]

Cited: 7 times

View full text PDF listing >>



Hippocampal epileptogenesis in autoimmune encephalitis.

Michele Romoli, Paraskevi Krashia, Arjune Sen, Diego Franciotta, Matteo Gastaldi, Annalisa Nobili, Andrea Mancini, Elena Nardi Cesarini, Pasquale Nigro, Nicola Tambasco, Nicola B Mercuri, Lucilla Parnetti, Massimiliano Di Filippo, Marcello D'Amelio, Sarosh R Irani, Cinzia Costa, Paolo Calabresi,

<h4>Objective</h4>Autoantibody-mediated forms of encephalitis (AE) include neurological disorders characterized by subacute memory loss, movement disorders, and, often, frequent, focal epileptic seizures. Yet, the electrophysiological effects of these autoantibodies on neuronal function have received little attention. In this study, we assessed the effects of CSF containing autoantibodies on intrinsic and extrinsic ... Read more >>

Ann Clin Transl Neurol (Annals of clinical and translational neurology)
[2019, 6(11):2261-2269]

Cited: 0 times

View full text PDF listing >>



Bortezomib-Responsive Refractory Anti-N-Methyl-d-Aspartate Receptor Encephalitis.

Ramona Cordani, Concetta Micalizzi, Thea Giacomini, Matteo Gastaldi, Diego Franciotta, Francesca Fioredda, Silvia Buratti, Giovanni Morana, Daniela Pirlo, Salvatore Renna, Elio Castagnola, Marco Risso, Paola Lanteri, Maria Stella Vari, Maria Margherita Mancardi,

BACKGROUND:Anti-N-methyl-d-aspartate receptor encephalitis is a central nervous system inflammatory autoimmune disease affecting adults and children. The use of first- and second-line immunotherapies is supported. Recent reports suggest the efficacy of bortezomib in severe anti-N-methyl-d-aspartate encephalitis in adult patients not responsive to second-line treatment; there are no data about pediatric patients. ... Read more >>

Pediatr Neurol (Pediatric neurology)
[2020, 103:61-64]

Cited: 1 time

View full text PDF listing >>



Placing CD20-targeted B cell depletion in multiple sclerosis therapeutic scenario: Present and future perspectives.

Emanuele D'Amico, Aurora Zanghì, Matteo Gastaldi, Francesco Patti, Mario Zappia, Diego Franciotta,

Multiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS) that traditionally has been considered to be mediated primarily by T cells. Increasing evidence, however, suggests the fundamental role of B cells in the pathogenesis and development of the disease. Recently, anti-CD20 B cell-based therapies have ... Read more >>

Autoimmun Rev (Autoimmunity reviews)
[2019, 18(7):665-672]

Cited: 3 times

View full text PDF listing >>



Management of antibody-mediated autoimmune encephalitis in adults and children: literature review and consensus-based practical recommendations.

Luigi Zuliani, Margherita Nosadini, Matteo Gastaldi, Marianna Spatola, Raffaele Iorio, Marco Zoccarato, Sara Mariotto, Piera De Gaspari, Francesco Perini, Sergio Ferrari, Amelia Evoli, Stefano Sartori, Diego Franciotta, Bruno Giometto,

Autoimmune encephalitis associated with antibodies against neuronal surface targets (NSAE) are rare but still underrecognized conditions that affect adult and pediatric patients. Clinical guidelines have recently been published with the aim of providing diagnostic clues regardless of antibody status. These syndromes are potentially treatable but the choice of treatment and ... Read more >>

Neurol Sci (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2019, 40(10):2017-2030]

Cited: 2 times

View full text PDF listing >>



Conventional brain MRI features distinguishing limbic encephalitis from mesial temporal glioma.

Marco Zoccarato, Silvia Valeggia, Luigi Zuliani, Matteo Gastaldi, Sara Mariotto, Diego Franciotta, Sergio Ferrari, Giuseppe Lombardi, Vittorina Zagonel, Piera De Gaspari, Mario Ermani, Alessio Signori, Anna Pichiecchio, Bruno Giometto, Renzo Manara,

<h4>Purpose</h4>Radiological hallmark of autoimmune limbic encephalitis (LE) is a hyperintense signal in MRI T2-weighted images of mesial temporal structures. We aimed to identify conventional magnetic resonance imaging (MRI) features that can help distinguish LE from temporal glioma.<h4>Methods</h4>Brain MRIs of 25 patients affected by antibody-positive autoimmune LE, 24 patients affected by ... Read more >>

Neuroradiology (Neuroradiology)
[2019, 61(8):853-860]

Cited: 2 times

View full text PDF listing >>



Serum and CSF neurofilament light chain levels in antibody-mediated encephalitis.

Sara Mariotto, Alberto Gajofatto, Luigi Zuliani, Marco Zoccarato, Matteo Gastaldi, Diego Franciotta, Gaetano Cantalupo, Francesca Piardi, Alberto Polo, Daniela Alberti, Stefano Sartori, Gianluigi Zanusso, Luigi Agrò, Rita Demurtas, GianPietro Sechi, Elia Sechi, Salvatore Monaco, Sergio Ferrari,

Circulating and cerebrospinal fluid (CSF) neurofilament light chain (NfL) levels represent a reliable indicator of disease activity and axonal damage in different neuroinflammatory conditions. Recently, high CSF NfL levels have been detected in active autoimmune encephalitis, as opposed to significant lower levels after clinical improvement. The aim of the present ... Read more >>

J Neurol (Journal of neurology)
[2019, 266(7):1643-1648]

Cited: 1 time

View full text PDF listing >>



Neurofilament light chain serum levels reflect disease severity in MOG-Ab associated disorders.

Sara Mariotto, Sergio Ferrari, Matteo Gastaldi, Diego Franciotta, Elia Sechi, Ruggero Capra, Chiara Mancinelli, Kathrin Schanda, Daniela Alberti, Riccardo Orlandi, Roberto Bombardi, Luigi Zuliani, Marco Zoccarato, Maria Donata Benedetti, Raffaella Tanel, Francesca Calabria, Francesca Rossi, Antonino Pavone, Luisa Grazian, GianPietro Sechi, Lucia Batzu, Noemi Murdeu, Francesco Janes, Vincenza Fetoni, Daniela Fulitano, Gianola Stenta, Lisa Federle, Gaetano Cantalupo, Markus Reindl, Salvatore Monaco, Alberto Gajofatto,

J Neurol Neurosurg Psychiatry (Journal of neurology, neurosurgery, and psychiatry)
[2019, 90(11):1293-1296]

Cited: 4 times

View full text PDF listing >>



Clinical, laboratory features, and prognostic factors in adult acute transverse myelitis: an Italian multicenter study.

Pasquale Annunziata, Gianni Masi, Chiara Cioni, Matteo Gastaldi, Enrico Marchioni, Emanuele D'amico, Francesco Patti, Alice Laroni, Gianluigi Mancardi, Francesca Vitetta, Patrizia Sola,

<h4>Objectives</h4>We compared the clinical, laboratory, and radiological features of different subgroups of acute transverse myelitis (ATM) diagnosed according to the criteria established by the Transverse Myelitis Consortium Working Group (TMCWG) as well as of non-inflammatory acute transverse myelopathies (NIATM) to identify possible short- and long-term prognostic factors.<h4>Methods</h4>A multicenter and retrospective ... Read more >>

Neurol Sci (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2019, 40(7):1383-1391]

Cited: 1 time

View full text PDF listing >>



Advertisement

Disclaimer
1.4157 s