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Author Martina Mosing

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Assessment of Postnatal Pulmonary Adaption in Bovine Neonates Using Electric Impedance Tomography (EIT).

Ulrich Bleul, Corina Wey, Carolina Meira, Andreas Waldmann, Martina Mosing,

Several aspects of postnatal pulmonary adaption in the bovine neonate remain unclear, particularly the dynamics and regional ventilation of the lungs. We used electric impedance tomography (EIT) to measure changes in ventilation in the first 3 weeks of life in 20 non-sedated neonatal calves born without difficulty in sternal recumbency. ... Read more >>

Animals (Basel) (Animals : an open access journal from MDPI)
[2021, 11(11):]

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Electrical impedance tomography to measure lung ventilation distribution in healthy horses and horses with left-sided cardiac volume overload.

Muriel Sacks, David P Byrne, Nicolas Herteman, Cristy Secombe, Andy Adler, Giselle Hosgood, Anthea L Raisis, Martina Mosing,

<h4>Background</h4>Left-sided cardiac volume overload (LCVO) can cause fluid accumulation in lung tissue changing the distribution of ventilation, which can be evaluated by electrical impedance tomography (EIT).<h4>Objectives</h4>To describe and compare EIT variables in horses with naturally occurring compensated and decompensated LCVO and compare them to a healthy cohort.<h4>Animals</h4>Fourteen adult horses, including ... Read more >>

J Vet Intern Med (Journal of veterinary internal medicine)
[2021, 35(5):2511-2523]

Cited: 2 times

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Exercise-induced airflow changes in horses with asthma measured by electrical impedance tomography.

Nicolas Herteman, Martina Mosing, Andreas D Waldmann, Vinzenz Gerber, Angelika Schoster,

<h4>Background</h4>Equine asthma (EA) causes airflow impairment, which increases in severity with exercise. Electrical impedance tomography (EIT) is an imaging technique that can detect airflow changes in standing healthy horses during a histamine provocation test.<h4>Objectives</h4>To explore EIT-calculated flow variables before and after exercise in healthy horses and horses with mild-to-moderate (MEA) ... Read more >>

J Vet Intern Med (Journal of veterinary internal medicine)
[2021, 35(5):2500-2510]

Cited: 1 time

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Use of Electrical Impedance Tomography (EIT) to Estimate Tidal Volume in Anaesthetized Horses Undergoing Elective Surgery.

Benedetta Crivellari, Anthea Raisis, Giselle Hosgood, Andreas D Waldmann, David Murphy, Martina Mosing,

This study explores the application of electric impedance tomography (EIT) to estimate tidal volume (VT) by measuring impedance change per breath (∆Z<sub>breath</sub>). Seventeen healthy horses were anaesthetised and mechanically ventilated for elective procedures requiring dorsal recumbency. Spirometric VT (VT<sub>SPIRO</sub>) and ∆Z<sub>breath</sub> were recorded periodically; up to six times throughout anaesthesia. ... Read more >>

Animals (Basel) (Animals : an open access journal from MDPI)
[2021, 11(5):]

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Can bronchoconstriction and bronchodilatation in horses be detected using electrical impedance tomography?

Cristy Secombe, Andy Adler, Giselle Hosgood, Anthea Raisis, Martina Mosing,

<h4>Background</h4>Electrical impedance tomography (EIT) generates images of the lungs based on impedance change and was able to detect changes in airflow after histamine challenge in horses.<h4>Objectives</h4>To confirm that EIT can detect histamine-provoked changes in airflow and subsequent drug-induced bronchodilatation. Novel EIT flow variables were developed and examined for changes in ... Read more >>

J Vet Intern Med (Journal of veterinary internal medicine)
[2021, 35(4):2035-2044]

Cited: 2 times

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Comparison of pulmonary function in isoflurane anaesthetized ventilated sheep (Ovis aries) following administration of intravenous xylazine versus medetomidine.

Anthea L Raisis, Giselle L Hosgood, Nicholas Crawford, Sabine Kästner, Gabrielle C Musk, Peter Herrmann, Martina Mosing,

Alpha<sub>2</sub> receptor agonists (alpha<sub>2</sub>-agonists) are useful sedative and analgesic agents in sheep, but have adverse pulmonary effects, which are reportedly similar between different alpha<sub>2</sub>-agonists. This randomized crossover study compared pulmonary function after intravenous administration of an alpha<sub>2</sub>-agonist, either xylazine or an equipotent dose of medetomidine in 34 female sheep anaesthetized ... Read more >>

Lab Anim (Laboratory animals)
[2021, 55(5):443-452]

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What hinders pulmonary gas exchange and changes distribution of ventilation in immobilized white rhinoceroses (Ceratotherium simum) in lateral recumbency?

Martina Mosing, Andreas D Waldmann, Muriel Sacks, Peter Buss, Jordyn M Boesch, Gareth E Zeiler, Giselle Hosgood, Robin D Gleed, Michele Miller, Leith C R Meyer, Stephan H Böhm,

This study used electrical impedance tomography (EIT) measurements of regional ventilation and perfusion to elucidate the reasons for severe gas exchange impairment reported in rhinoceroses during opioid-induced immobilization. EIT values were compared with standard monitoring parameters to establish a new monitoring tool for conservational immobilization and future treatment options. Six ... Read more >>

J Appl Physiol (1985) (Journal of applied physiology (Bethesda, Md. : 1985))
[2020, 129(5):1140-1149]

Cited: 2 times

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Evaluation of histamine-provoked changes in airflow using electrical impedance tomography in horses.

Cristy Secombe, Andreas D Waldmann, Giselle Hosgood, Martina Mosing,

<h4>Background</h4>Electrical impedance tomography (EIT) generates thoracic impedance images of the lungs and has been used to assess ventilation in horses. This technique may have application in the detection of changes in airflow associated with equine asthma.<h4>Objectives</h4>The objective was to determine if histamine-induced airflow changes observed with flowmetric plethysmography (Δflow) could also ... Read more >>

Equine Vet J (Equine veterinary journal)
[2020, 52(4):556-563]

Cited: 4 times

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Thoracic EIT in 3D: experiences and recommendations.

Bartłomiej Grychtol, Johannes Peter Schramel, Fabian Braun, Thomas Riedel, Ulrike Auer, Martina Mosing, Christina Braun, Andreas D Waldmann, Stephan H Böhm, Andy Adler,

<h4>Objective</h4>In EIT applications to the thorax, a single electrode plane has typically been used to reconstruct a transverse 2D 'slice'. However, such images can be misleading as EIT is sensitive to contrasts above and below the electrode plane, and ventilation and aeration inhomogeneities can be distributed in complex ways. Using ... Read more >>

Physiol Meas (Physiological measurement)
[2019, 40(7):074006]

Cited: 4 times

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Cardiovascular effects of two adenosine constant rate infusions in anaesthetized dogs.

Fabiola B Joerger, Mathias Dennler, Carolina Meira, Martina Mosing, Henning Richter, Simone K Ringer,

<h4>Objective</h4>Adenosine induces vasodilatation. The aim of this study was to investigate cardiovascular effects of two adenosine constant rate infusion (CRI) doses in dogs.<h4>Study design</h4>Experimental, longitudinal repeated measure design.<h4>Animals</h4>Ten healthy purpose-bred Beagle dogs.<h4>Methods</h4>Each dog was sedated with butorphanol. Anaesthesia was induced with propofol intravenously and maintained with sevoflurane (inspired oxygen fraction = ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2019, 46(3):289-298]

Cited: 1 time

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Monitoring changes in distribution of pulmonary ventilation by functional electrical impedance tomography in anaesthetized ponies.

Ulrike Auer, J Peter Schramel, Yves P Moens, Martina Mosing, Christina Braun,

OBJECTIVE:To assess changes in the distribution in pulmonary ventilation in anaesthetized ponies using electrical impedance tomography (EIT). STUDY DESIGN:Prospective experimental study. ANIMALS:A group of eight adult pony geldings. METHODS:General anaesthesia was induced and maintained using isoflurane in oxygen with volume-controlled ventilation [tidal volume (VT) (10 mL kg-1), respiratory rate (8-12 ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2019, 46(2):200-208]

Cited: 0 times

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Impact of Trendelenburg (head down) and reverse Trendelenburg (head up) position on respiratory and cardiovascular function in anaesthetized horses.

Anna Binetti, Martina Mosing, Muriel Sacks, Luc Duchateau, Frank Gasthuys, Stijn Schauvliege,

<h4>Objective</h4>To describe the cardiorespiratory effects of a change in table position in anaesthetized horses.<h4>Study design</h4>Prospective, crossover, randomized, experimental study.<h4>Animals</h4>Six adult horses (mean body weight 621 ± 59 kg, aged 13 ± 4 years).<h4>Methods</h4>The horses were anaesthetized twice in dorsal recumbency. They were either placed in the Trendelenburg position (head down; ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2018, 45(6):760-771]

Cited: 2 times

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Agreement between invasive blood pressure measured centrally and peripherally in anaesthetized horses.

Keely At Wilson, Anthea L Raisis, Eleanor A Drynan, Martina Mosing, Guy D Lester, Jemma Hayman, Giselle L Hosgood,

<h4>Objective</h4>To determine the agreement of invasive blood pressure measured in the facial, metatarsal and carotid arteries, and evaluate the effects of two haemodynamic conditions on agreement.<h4>Study design</h4>Prospective randomized study.<h4>Animals</h4>A group of eight horses aged 7 (4-23) years with a body weight of 493 ± 33 kg.<h4>Methods</h4>Horses were anaesthetized and positioned in dorsal recumbency. ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2018, 45(4):467-476]

Cited: 1 time

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Physiologic Factors Influencing the Arterial-To-End-Tidal CO2 Difference and the Alveolar Dead Space Fraction in Spontaneously Breathing Anesthetised Horses.

Martina Mosing, Stephan H Böhm, Anthea Rasis, Giselle Hoosgood, Ulrike Auer, Gerardo Tusman, Regula Bettschart-Wolfensberger, Johannes P Schramel,

The arterial to end-tidal CO<sub>2</sub> difference (P<sub>(a-ET)</sub>CO<sub>2</sub>) and alveolar dead space fraction (VDalv<sub>frac</sub> = P<sub>(a-ET)</sub>CO<sub>2</sub>/PaCO<sub>2</sub>), are used to estimate Enghoff's "pulmonary dead space" (V/Q<sub>Eng</sub>), a factor which is also influenced by venous admixture and other pulmonary perfusion abnormalities and thus is not just a measure of dead space as the name suggests. ... Read more >>

Front Vet Sci (Frontiers in veterinary science)
[2018, 5:58]

Cited: 4 times

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Comparison of three continuous positive airway pressure (CPAP) interfaces in healthy Beagle dogs during medetomidine-propofol constant rate infusions.

Carolina Meira, Fabiola B Joerger, Annette P N Kutter, Andreas Waldmann, Simone K Ringer, Stephan H Böehm, Samuel Iff, Martina Mosing,

To compare the efficacy of three continuous positive airway pressure (CPAP) interfaces in dogs on gas exchange, lung volumes, amount of leak during CPAP and rebreathing in case of equipment failure or disconnection.Randomized, prospective, crossover, experimental trial.Ten purpose-bred Beagle dogs.Dogs were in dorsal recumbency during medetomidine-propofol constant rate infusions, breathing ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2018, 45(2):145-157]

Cited: 1 time

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Ventilatory incidents monitored by electrical impedance tomography in an anaesthetized orangutan (Pongo abelii).

Martina Mosing, Muriel Sacks, Stamatios A Tahas, Elisabeth Ranninger, Stephan H Böhm, Ivo Campagnia, Andreas D Waldmann,

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2017, 44(4):973-976]

Cited: 0 times

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Evaluation of three tidal volumes (10, 12 and 15 mL kg-1) in dogs for controlled mechanical ventilation assessed by volumetric capnography: a randomized clinical trial.

Seline Bumbacher, Johannes P Schramel, Martina Mosing,

<h4>Objective</h4>To evaluate three routinely used tidal volumes (V<sub>T</sub>; 10, 12 and 15 mL kg<sup>-1</sup>) for controlled mechanical ventilation (CMV) in lung-healthy anaesthetized dogs by assessing alveolar ventilation (VT<sub>alv</sub>) and dead space (DS).<h4>Study design</h4>Prospective, randomized clinical trial.<h4>Animals</h4>A total of 36 client-owned dogs.<h4>Methods</h4>Dogs were randomly allocated to a V<sub>T</sub> of 10 (G<sub>10</sub>), 12 (G<sub>12</sub>) ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2017, 44(4):775-784]

Cited: 6 times

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Regional ventilation distribution and dead space in anaesthetized horses treated with and without continuous positive airway pressure: novel insights by electrical impedance tomography and volumetric capnography.

Martina Mosing, Ulrike Auer, Paul MacFarlane, David Bardell, Johannes P Schramel, Stephan H Böhm, Regula Bettschart-Wolfensberger, Andreas D Waldmann,

The aim of this study was to evaluate the effect of continuous positive airway pressure (CPAP) on regional distribution of ventilation and dead space in anaesthetized horses.Randomized, experimental, crossover study.A total of eight healthy adult horses.Horses were anaesthetized twice with isoflurane in 50% oxygen and medetomidine as continuous infusion in ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2018, 45(1):31-40]

Cited: 5 times

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Experimental evaluation of four airway devices in anaesthetized New Zealand White rabbits.

Sandra Wenger, Désirée Müllhaupt, Stefanie Ohlerth, Sarah Prasse, Karina Klein, Bianca da Silva Valente, Martina Mosing,

<h4>Objective</h4>To compare airway management during induction of anaesthesia, spontaneous ventilation (SV) and controlled mechanical ventilation (CMV), using an endotracheal tube (ETT), laryngeal mask (LM), rabbit-specific supraglottic airway device (v-gel) or facemask (FM).<h4>Study design</h4>Prospective randomized crossover experiment.<h4>Animals</h4>Ten New Zealand White rabbits.<h4>Methods</h4>After premedication, rabbits were randomly allocated to four groups: 1) ETT; ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2017, 44(3):529-537]

Cited: 3 times

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Regional distribution of ventilation in horses in dorsal recumbency during spontaneous and mechanical ventilation assessed by electrical impedance tomography: a case series.

Martina Mosing, Charlotte Marly-Voquer, Paul MacFarlane, David Bardell, Stephan H Böhm, Regula Bettschart-Wolfensberger, Andreas D Waldmann,

<h4>Objective</h4>To evaluate the regional distribution of ventilation in horses during spontaneous breathing and controlled mechanical ventilation (CMV) using electrical impedance tomography (EIT).<h4>Study design</h4>Prospective, experimental case series.<h4>Animals</h4>Four anaesthetized experimental horses.<h4>Methods</h4>Horses were anaesthetized with isoflurane in an oxygen-air mixture and medetomidine continuous rate infusion, placed in dorsal recumbency with an EIT belt ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2017, 44(1):127-132]

Cited: 7 times

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Volumetric capnography to diagnose venous air embolism in an anaesthetised horse.

Muriel Sacks, Martina Mosing,

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2017, 44(1):189-190]

Cited: 3 times

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Horses Auto-Recruit Their Lungs by Inspiratory Breath Holding Following Recovery from General Anaesthesia.

Martina Mosing, Andreas D Waldmann, Paul MacFarlane, Samuel Iff, Ulrike Auer, Stephan H Bohm, Regula Bettschart-Wolfensberger, David Bardell,

This study evaluated the breathing pattern and distribution of ventilation in horses prior to and following recovery from general anaesthesia using electrical impedance tomography (EIT). Six horses were anaesthetised for 6 hours in dorsal recumbency. Arterial blood gas and EIT measurements were performed 24 hours before (baseline) and 1, 2, ... Read more >>

PLoS One (PloS one)
[2016, 11(6):e0158080]

Cited: 6 times

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Continuous positive airway pressure (CPAP) decreases pulmonary shunt in anaesthetized horses.

Martina Mosing, Paul MacFarlane, David Bardell, Laura Lüthi, Peter J Cripps, Regula Bettschart-Wolfensberger,

<h4>Objective</h4>To evaluate the effects of continuous positive airway pressure (CPAP) on intrapulmonary shunt, cardiac output and oxygen delivery in horses subjected to a 6 hour period of general anaesthesia.<h4>Study design</h4>Randomized, experimental, crossover study.<h4>Animals</h4>Ten healthy adult horses.<h4>Methods</h4>Following medetomidine, diazepam and ketamine administration, orotracheal intubation was performed and horses positioned in dorsal recumbency. ... Read more >>

Vet Anaesth Analg (Veterinary anaesthesia and analgesia)
[2016, 43(6):611-622]

Cited: 6 times

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Effects of contrast medium injection technique on attenuation values of adrenal glands in healthy dogs during contrast-enhanced computed tomography.

Alexandra Blaser, Matthias Dennler, Martina Mosing, Thomas C Gent, Guido Santner, Sandro Imhasly, Felicitas S Boretti, Claudia E Reusch, Patrick Kircher, Nadja S Sieber-Ruckstuhl,

<h4>Objective</h4>To assess the effects of 3 contrast medium injection techniques on attenuation values for canine adrenal glands during contrast-enhanced CT.<h4>Animals</h4>9 healthy Beagles.<h4>Procedures</h4>3 protocols were evaluated in a randomized cross-over design study: 700 mg of iodine/kg at a constant injection rate over 20 seconds (full-dose constant rate), the same dose at ... Read more >>

Am J Vet Res (American journal of veterinary research)
[2016, 77(2):144-150]

Cited: 2 times

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The influence of acute pulmonary hypertension on cardiac output measurements: calibrated pulse contour analysis, transpulmonary and pulmonary artery thermodilution against a modified Fick method in an animal model.

Annette P N Kutter, Martina Mosing, Sonja Hartnack, Joanna Raszplewicz, Martina Renggli, Jacqueline Y Mauch, Christoph K Hofer,

<h4>Background</h4>In critically ill patients with significant pulmonary hypertension (PH), close perioperative cardiovascular monitoring is mandatory, considering the increased morbidity and mortality in this patient group. Although the pulmonary artery catheter is still the standard for the diagnosis of PH, its use to monitor cardiac output (CO) in patients with PH ... Read more >>

Anesth Analg (Anesthesia and analgesia)
[2015, 121(1):99-107]

Cited: 2 times

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