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Author Marta Torrens

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Managing dual disorders: a statement by the Informal Scientific Network, UN Commission on Narcotic Drugs.

Nora D Volkow, Marta Torrens, Vladimir Poznyak, Elizabeth Sáenz, Anja Busse, Wataru Kashino, Dzmitry Krupchanka, Devora Kestel, Giovanna Campello, Gilberto Gerra,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2020, 19(3):396-397]

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Traumatic Events in Dual Disorders: Prevalence and Clinical Characteristics.

Laura Blanco, Albert Sió, Bridget Hogg, Ricard Esteve, Joaquim Radua, Aleix Solanes, Itxaso Gardoki-Souto, Rosa Sauras, Adriana Farré, Claudio Castillo, Alicia Valiente-Gómez, Víctor Pérez, Marta Torrens, Benedikt L Amann, Ana Moreno-Alcázar,

Psychological trauma has been identified in substance use disorders (SUD) as a major etiological risk factor. However, detailed and systematic data about the prevalence and types of psychological trauma in dual disorders have been scarce to date. In this study, 150 inpatients were recruited and cross-sectionally screened on their substance ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(8):]

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Sex-specific Associations of Alcohol Withdrawal in Patients Admitted for the Treatment of Alcohol Use Disorder.

Arantza Sanvisens, Paola Zuluaga, Antoni Short, Gabriel Rubio, Antoni Gual, Marta Torrens, Daniel Fuster, Ferran Bolao, Fernando Rodríguez de Fonseca, Roberto Muga, ,

OBJECTIVES:There are sex differences in the pattern of alcohol consumption and in the complications of alcohol use disorder (AUD). We aimed to identify sex-specific differences in the factors associated with alcohol withdrawal syndrome (AWS) among patients that requested a first treatment for AUD. METHODS:We enrolled 313 patients (75% men) with ... Read more >>

J Addict Med (Journal of addiction medicine)
[2020, :]

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Alcohol Induced Depression: Clinical, Biological and Genetic Features.

Adriana Farré, Judit Tirado, Nino Spataro, María Alías-Ferri, Marta Torrens, Francina Fonseca,

BACKGROUND:In clinical practice, there is the need to have clinical and biological markers to identify induced depression. The objective was to investigate clinical, biological and genetic differences between Primary Major Depression (Primary MD) and Alcohol Induced MD (AI-MD). METHODS:Patients, of both genders, were recruited from psychiatric hospitalisation units. The PRISM ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(8):]

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Personality Disorders in the ICD-11: Spanish Validation of the PiCD and the SASPD in a Mixed Community and Clinical Sample.

Fernando Gutiérrez, Anton Aluja, José Ruiz, Luis F García, Miguel Gárriz, Alfonso Gutiérrez-Zotes, David Gallardo-Pujol, Maria V Navarro-Haro, Miquel Alabèrnia-Segura, Joan Ignasi Mestre-Pintó, Marta Torrens, Josep M Peri, Bárbara Sureda, Joaquim Soler, Juan Carlos Pascual, Gemma Vall, Natalia Calvo, Marc Ferrer, Joshua R Oltmanns, Thomas A Widiger,

The International Classification of Diseases-11th revision (ICD-11) classification of personality disorders is the official diagnostic system that is used all over the world, and it has recently been renewed. However, as yet very few data are available on its performance. This study examines the Personality Inventory for ICD-11 (PiCD), which ... Read more >>

Assessment (Assessment)
[2020, :1073191120936357]

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Oral Administration of Cannabis and Δ-9-tetrahydrocannabinol (THC) Preparations: A Systematic Review.

Lourdes Poyatos, Ana Pilar Pérez-Acevedo, Esther Papaseit, Clara Pérez-Mañá, Soraya Martin, Olga Hladun, Adrià Siles, Marta Torrens, Francesco Paolo Busardo, Magí Farré,

BACKGROUND AND OBJECTIVE:Changes in cannabis legalization regimes in several countries have influenced the diversification of cannabis use. There is an ever-increasing number of cannabis forms available, which are gaining popularity for both recreational and therapeutic use. From a therapeutic perspective, oral cannabis containing Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) is a ... Read more >>

Medicina (Kaunas) (Medicina (Kaunas, Lithuania))
[2020, 56(6):]

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Clinical-Based and Expert Selection of Terms Related to Depression for Twitter Streaming and Language Analysis.

Angela Leis, Miguel-Angel Mayer, Francesco Ronzano, Marta Torrens, Claudio Castillo, Laura I Furlong, Ferran Sanz,

People use language to express their thoughts and feelings, unveiling important aspects of their psychological traits and social interactions. Although there are several studies describing methodologies to create a collection of words in English related to depression and other conditions, in most of them the selection of words is not ... Read more >>

Stud Health Technol Inform (Studies in health technology and informatics)
[2020, 270:921-925]

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Cannabis research: Risks of recreational use and potential medical applications.

Rafael Maldonado, Marta Torrens,

Eur Neuropsychopharmacol (European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology)
[2020, 36:167-168]

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Abstinent patients with alcohol use disorders show an altered plasma cytokine profile: Identification of both interleukin 6 and interleukin 17A as potential biomarkers of consumption and comorbid liver and pancreatic diseases.

Nuria García-Marchena, Rosa Maza-Quiroga, Antonia Serrano, Vicente Barrios, Nerea Requena-Ocaña, Juan Suárez, Julie Ann Chowen, Jesús Argente, Gabriel Rubio, Marta Torrens, Meritxell López-Gallardo, Eva María Marco, Estela Castilla-Ortega, Luis Javier Santín, Fernando Rodríguez de Fonseca, Francisco Javier Pavón, Pedro Araos,

BACKGROUND:Recent studies have demonstrated that alcohol consumption can modulate the immune system by directly activating natural immunity and triggering inflammatory processes in the central nervous system and in peripheral organs, such as the liver and pancreas. Patients with alcohol use disorders have an elevated frequency of comorbid mental disorders and ... Read more >>

J. Psychopharmacol. (Oxford) (Journal of psychopharmacology (Oxford, England))
[2020, :269881120928176]

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Professional perception of clozapine use in patients with dual psychosis.

Lara Grau-López, Nestor Szerman, Marta Torrens, Ignacio Basurte, Pablo Vega, José Martínez-Raga, Miguel Casas, Carlos Roncero,

INTRODUCTION:Patients with psychotic disorders often have substance use disorders and other addictions. The objective of this study was to know the current treatment situation of these patients focusing on clozapine, which was proposed in most consensus as antipsychotic of first choice in this indication. MATERIAL AND METHODS:A survey with 14 ... Read more >>

Actas Esp Psiquiatr (Actas espanolas de psiquiatria)
[2020, 48(3):99-105]

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Effects of cannabis exposure in the prenatal and adolescent periods: Preclinical and clinical studies in both sexes.

Judith Tirado-Muñoz, Ana Belen Lopez-Rodriguez, Francina Fonseca, Magi Farré, Marta Torrens, Maria-Paz Viveros,

Cannabis is the most commonly used illicit drug among adolescents and young adults, including pregnant women. There is substantial evidence for a significant association between prenatal cannabis exposure and lower birth weight in offspring, and mixed results regarding later behavioural outcomes in the offspring. Adolescent cannabis use, especially heavy use, ... Read more >>

Front Neuroendocrinol (Frontiers in neuroendocrinology)
[2020, 57:100841]

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MDMA interactions with pharmaceuticals and drugs of abuse.

Esther Papaseit, Clara Pérez-Mañá, Marta Torrens, Adriana Farré, Lourdes Poyatos, Olga Hladun, Arantza Sanvisens, Roberto Muga, Magi Farré,

Introduction: MDMA (3,4-methylenedioxymethamphetamine), a synthetic ring-substituted amphetamine, has become one of the most widely used recreational psychostimulant drugs in the world. Among recreational ecstasy/MDMA users, polydrug use is a phenomenon whose common purpose is to experience the synergistic effect of the combined drugs, moderate MDMA effects, prevent potential toxicity, enhance ... Read more >>

Expert Opin Drug Metab Toxicol (Expert opinion on drug metabolism & toxicology)
[2020, 16(5):357-369]

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Acute Effects of 2C-E in Humans: An Observational Study.

Esther Papaseit, Eulalia Olesti, Clara Pérez-Mañá, Marta Torrens, Marc Grifell, Mireia Ventura, Oscar J Pozo, Elizabeth B de Sousa Fernandes Perna, Johannes G Ramaekers, Rafael de la Torre, Magí Farré,

2,5-Dimethoxy-4-ethylphenethylamine (2C-E) is psychedelic phenylethylamine, with a chemical structure similar to mescaline, used as new psychoactive substance (NPS). It inhibits norepinephrine and serotonin uptake and, more relevant, acts as a partial agonist of the serotonin 2A (5-HT2 A), 2B (5-HT2 B), and (5-HT2 C) receptors. Consumers have reported that 2C-E ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2020, 11:233]

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Cocaine and depressive disorders: When standard clinical diagnosis is insufficient.

Maria Alías-Ferri, Nuria García-Marchena, Joan Ignasi Mestre-Pintó, Pedro Araos, Esperanza Vergara-Moragues, Francina Fonseca, Francisco González-Saiz, Fernando Rodríguez de Fonseca, Marta Torrens, Neurodep Group,

BACKGROUND:Cocaine use is a growing global health problem and patients with cocaine use disorders (CUD) present several complications, including high rates of major depression. These subjects present two types of major depressive disorder (MDD): primary major depressive disorder (P-MDD) and cocaine-induced major depressive disorder (CI-MDD). To improve treatment, it is ... Read more >>

Adicciones (Adicciones)
[2020, 0(0):1321]

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Drug-related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (slamsex): Data from the U-SEX GESIDA 9416 Study.

Helen Dolengevich-Segal, Alicia Gonzalez-Baeza, Jorge Valencia, Eulalia Valencia-Ortega, Alfonso Cabello, Maria Jesus Tellez-Molina, Maria Jesus Perez-Elias, Regino Serrano, Leire Perez-Latorre, Luz Martin-Carbonero, Sari Arponen, Jose Sanz-Moreno, Sara De la Fuente, Otilia Bisbal, Ignacio Santos, Jose Luis Casado, Jesus Troya, Miguel Cervero-Jimenez, Sara Nistal, Guillermo Cuevas, Javier Correas-Lauffer, Marta Torrens, Pablo Ryan, ,

OBJECTIVES:Sexualized intravenous drug use, also known as slamsex, seems to be increasing among HIV-positive men who have sex with men (MSM). Physical and psychopathological symptoms have previously been reported in this population, although research on the subject of slamsex is scarce. The objectives of our study were to describe the ... Read more >>

PLoS One (PloS one)
[2019, 14(12):e0220272]

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Integration of harm reduction and treatment into care centres for substance use: The Barcelona model.

Oleguer Parés-Badell, Gabriela Barbaglia, Natanya Robinowitz, Xavier Majó, Marta Torrens, Albert Espelt, Montse Bartroli, Mercè Gotsens, Maria Teresa Brugal,

Int. J. Drug Policy (The International journal on drug policy)
[2020, 76:102614]

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Responding to global stimulant use: challenges and opportunities.

Michael Farrell, Natasha K Martin, Emily Stockings, Annick Bórquez, Javier A Cepeda, Louisa Degenhardt, Robert Ali, Lucy Thi Tran, Jürgen Rehm, Marta Torrens, Steve Shoptaw, Rebecca McKetin,

We did a global review to synthesise data on the prevalence, harms, and interventions for stimulant use, focusing specifically on the use of cocaine and amphetamines. Modelling estimated the effect of cocaine and amphetamine use on mortality, suicidality, and blood borne virus incidence. The estimated global prevalence of cocaine use ... Read more >>

Lancet (Lancet (London, England))
[2019, 394(10209):1652-1667]

Cited: 2 times

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Drug related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (Slamsex): Data from the U-SEX GESIDA 9416 Study

Helen Dolengevich-Segal, Alicia Gonzalez-Baeza, Jorge Valencia, Eulalia Valencia-Ortega, Alfonso Cabello, Maria Jesus Tellez Molina, Maria Jesus Perez Elias, Regino Serrano, Leire Perez Latorre, Luz Martín-Carbonero, Sari Arponen, Jose Sanz Moreno, Sara De La Fuente, Otilia Bisbal, Ignacio Santos, Jose Luis Casado, Jesus Troya, Miguel Cervero Jimenez, Sara Nistal, Guillermo Cuevas, Javier Correas Lauffer, Marta Torrens, Pablo Ryan, ,

ABSTRACT Objectives Intravenous sexualized drug use also known as slamsex seems to be increasing among HIV-positive men who have sex with men (MSM). This practice may entail severe consequences for physical and mental health in this population. Research on the subject is scarce. The aim of our study was to ... Read more >>

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Relationship between craving and impulsivity in patients with alcohol dependence with or without dual disorders in an outpatient treatment center: a descriptive study.

María Robles-Martínez, Miguel Ángel García-Carretero, Juan Gibert Rahola, Laia Rodríguez-Cintas, Raúl Felipe Palma-Álvarez, Alfonso Carlos Abad, Marta Sorribes, Marta Torrens, Carlos Roncero,

OBJECTIVES:To compare alcohol and other drugs abuse, state impulsivity, craving and the relationship between craving and impulsivity in alcohol-dependent patients with or without dual disorder attending to an alcohol treatment center in Cadiz town. METHOD:An observational, descriptive and transversal study performed on 112 alcohol dependent patient sample who were seeking ... Read more >>

Actas Esp Psiquiatr (Actas espanolas de psiquiatria)
[2019, 47(3):88-96]

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A Multicenter Phase II Rater-Blinded Randomized Controlled Trial to Compare the Effectiveness of Eye Movement Desensitization Reprocessing Therapy vs. Treatment as Usual in Patients With Substance Use Disorder and History of Psychological Trauma: A Study Design and Protocol.

Alicia Valiente-Gómez, Ana Moreno-Alcázar, Joaquim Radua, Bridget Hogg, Laura Blanco, W Lupo, Víctor Pérez, Maria Robles-Martínez, Marta Torrens, Benedikt L Amann,

Background: Psychological trauma has a strong negative impact on the onset, course and prognosis of substance use disorders (SUD). Few trauma-oriented treatment approaches have been trialed, but preliminary evidence exists of the efficacy of Eye Movement Desensitization and Reprocessing (EMDR) therapy in improving clinical symptoms in SUD patients. Objective: To ... Read more >>

(Frontiers in psychiatry)
[2019, 10:108]

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DSM-5 in patients seeking their first treatment for alcohol use disorder. Sex differences in the multicenter CohRTA study.

Arantza Sanvisens, Paola Zuluaga, Gabriel Rubio, Antoni Short, Antoni Gual, Francisco Javier Álvarez, Marta Torrens, Fernando Rodríguez de Fonseca, Roberto Muga, - Estudio CohRTA,

OBJECTIVE:We aimed to analyze sex differences in the DSM-5 criteria among patients admitted to  their first treatment of alcohol use disorder (AUD). METHODS:Assessment of AUD was carried out using DSM-5 diagnostic criteria in a multicenter study (CohRTA) within the Spanish Network on Addictive Disorders. Further, baseline questionnaires including socio-demographics, family ... Read more >>

Adicciones (Adicciones)
[2020, 32(2):136-144]

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Dose-Response Pharmacological Study of Mephedrone and Its Metabolites: Pharmacokinetics, Serotoninergic Effects, and Impact of CYP2D6 Genetic Variation.

Eulàlia Olesti, Magí Farré, Marcel Lí Carbó, Esther Papaseit, Clara Perez-Mañá, Marta Torrens, Samanta Yubero-Lahoz, Mitona Pujadas, Óscar J Pozo, Rafael de la Torre,

Mephedrone (MEPH), the most widely consumed synthetic cathinone, has been associated with acute toxicity episodes. The aim of this report was to study its metabolic disposition and the impact of genetic variation of CYP2D6 on MEPH metabolism, in a dose range compatible with its recreational use. A randomized, crossover, phase ... Read more >>

Clin. Pharmacol. Ther. (Clinical pharmacology and therapeutics)
[2019, 106(3):596-604]

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Soy Isoflavone Extract Does Not Increase the Intoxicating Effects of Acute Alcohol Ingestion in Human Volunteers.

Roser Martínez-Riera, Clara Pérez-Mañá, Esther Papaseit, Francina Fonseca, Rafael de la Torre, Nieves Pizarro, Marta Torrens, Magí Farré,

Soy beans contain isoflavones, including daidzein and genistein, with biological activities related to therapeutic effects in reducing osteoporosis, decreasing adverse menopausal manifestations, providing protection from cardiovascular diseases, and reducing hormone-dependent cancers and age-related cognitive-decline. Daidzein has been described as inhibiting the aldehyde-dehydrogenase-2 enzyme (ALDH2), and reducing alcohol use in clinical ... Read more >>

(Frontiers in pharmacology)
[2019, 10:131]

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Inflammatory mediators and dual depression: Potential biomarkers in plasma of primary and substance-induced major depression in cocaine and alcohol use disorders.

Nuria García-Marchena, Marta Barrera, Joan Ignasi Mestre-Pintó, Pedro Araos, Antonia Serrano, Clara Pérez-Mañá, Esther Papaseit, Francina Fonseca, Juan Jesús Ruiz, Fernando Rodríguez de Fonseca, Magí Farré, Francisco Javier Pavón, Marta Torrens,

Major depressive disorder (MDD) is the most prevalent comorbid mental disorder among people with substance use disorders. The MDD can be both primary and substance-induced and its accurate diagnosis represents a challenge for clinical practice and treatment response. Recent studies reported alterations in the circulating expression of inflammatory mediators in ... Read more >>

PLoS One (PloS one)
[2019, 14(3):e0213791]

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Therapeutic Use of LSD in Psychiatry: A Systematic Review of Randomized-Controlled Clinical Trials.

Juan José Fuentes, Francina Fonseca, Matilde Elices, Magí Farré, Marta Torrens,

Lysergic acid diethylamide (LSD) was studied from the 1950s to the 1970s to evaluate behavioral and personality changes, as well as remission of psychiatric symptoms in various disorders. LSD was used in the treatment of anxiety, depression, psychosomatic diseases and addiction. However, most of the studies were not performed under ... Read more >>

Front Psychiatry (Frontiers in psychiatry)
[2019, 10:943]

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