Full Text Journal Articles by
Author Marry M van den Heuvel Eibrink

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Echocardiography protocol for early detection of cardiac dysfunction in childhood cancer survivors in the multicenter DCCSS LATER 2 CARD study: Design, feasibility, and reproducibility.

Remy Merkx, Jan M Leerink, Elisabeth Lieke A M Feijen, Leontien C M Kremer, Esmée C de Baat, Louise Bellersen, Elvira C van Dalen, Eline van Dulmen-den Broeder, Margriet van der Heiden-van der Loo, Marry M van den Heuvel-Eibrink, Chris L de Korte, Jacqueline Loonen, Marloes Louwerens, Angela H E M Maas, Yigal M Pinto, Cécile M Ronckers, Arco J Teske, Wim J E Tissing, Andrica C H de Vries, Annelies M C Mavinkurve-Groothuis, Helena J H van der Pal, Gert Weijers, Wouter E M Kok, Livia Kapusta, ,

<h4>Background</h4>Cardiotoxicity is a well-known side effect after anthracyclines and chest radiotherapy in childhood cancer survivors (CCS). The DCCSS LATER 2 CARD (cardiology) study includes evaluation of echocardiographic measurements for early identification of CCS at highest risk of developing heart failure. This paper describes the design, feasibility, and reproducibility of the ... Read more >>

Echocardiography (Echocardiography (Mount Kisco, N.Y.))
[2021, :]

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Vitamin D supplementation for children with cancer: A systematic review and consensus recommendations.

Jenneke E van Atteveld, Iris E Verhagen, Marry M van den Heuvel-Eibrink, Hanneke M van Santen, Inge M van der Sluis, Natascia Di Iorgi, Jill H Simmons, Leanne M Ward, Sebastian J C M M Neggers,

<h4>Background</h4>Prevalent vitamin D deficiency (VDD) and low bone mineral density (BMD) have led to vitamin D supplementation for children with cancer, regardless vitamin D status. However, it remains unsettled whether this enhances bone strength. We sought to address this issue by carrying out a systematic review of the literature.<h4>Methods</h4>We conducted ... Read more >>

Cancer Med (Cancer medicine)
[2021, :]

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Methodology of the DCCSS later fatigue study: a model to investigate chronic fatigue in long-term survivors of childhood cancer.

Adriaan Penson, Sylvia van Deuren, Ewald Bronkhorst, Ellen Keizer, Tom Heskes, Marieke J H Coenen, Judith G M Rosmalen, Wim J E Tissing, Helena J H van der Pal, Andrica C H de Vries, Marry M van den Heuvel-Eibrink, Sebastian Neggers, Birgitta A B Versluys, Marloes Louwerens, Margriet van der Heiden-van der Loo, Saskia M F Pluijm, Martha Grootenhuis, Nicole Blijlevens, Leontien C M Kremer, Eline van Dulmen-den Broeder, Hans Knoop, Jacqueline Loonen,

<h4>Background</h4>A debilitating late effect for childhood cancer survivors (CCS) is cancer-related fatigue (CRF). Little is known about the prevalence and risk factors of fatigue in this population. Here we describe the methodology of the Dutch Childhood Cancer Survivor Late Effect Study on fatigue (DCCSS LATER fatigue study). The aim of ... Read more >>

BMC Med Res Methodol (BMC medical research methodology)
[2021, 21(1):106]

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Estimated clinical benefit of combining highly conformal target volumes with Volumetric-Modulated Arc Therapy (VMAT) versus conventional flank irradiation in pediatric renal tumors.

Joeri Mul, Enrica Seravalli, Mirjam E Bosman, Cornelis P van de Ven, Annemieke S Littooij, Martine van Grotel, Marry M van den Heuvel-Eibrink, Geert O Janssens,

<h4>Background</h4>For decades, Anterior-Posterior/Posterior-Anterior (AP/PA) photon beams were standard-of-care for flank irradiation in children with renal cancer. Recently, highly conformal flank target volumes were defined correcting for postoperative organ shift and intra-fraction motion.By radiotherapy treatment plan comparison, this study aims to estimate the clinical benefits and potential risks of combining highly ... Read more >>

Clin Transl Radiat Oncol (Clinical and translational radiation oncology)
[2021, 29:20-26]

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Presence of viremia during febrile neutropenic episodes in patients undergoing chemotherapy for malignant neoplasms.

Klára Obrová, Silke Grumaz, Marlene Remely, Stefan Czurda, Isabella Krickl, Susanne Herndlhofer, Karoline V Gleixner, Wolfgang R Sperr, Lisa Größlinger, Tijana Frank, Nuno Andrade, Teresa Egger-Matiqi, Christina Peters, Gernot Engstler, Michael Dworzak, Andishe Attarbaschi, Martine van Grotel, Marry M van den Heuvel-Eibrink, Ivan S Moiseev, Yuliya Rogacheva, Ludmilla Zubarovskaya, Natalia Zubarovskaya, Herbert Pichler, Anita Lawitschka, Elisabeth Koller, Felix Keil, Peter Valent, Kai Sohn, Thomas Lion,

The importance of viral infections as a leading cause of morbidity and mortality is well documented in severely immunosuppressed patients undergoing allogeneic stem cell transplantation. By contrast, viral infections generally receive less attention in patients with malignant disorders undergoing chemotherapy, where the onset of neutropenic fever is mostly associated with ... Read more >>

Am J Hematol (American journal of hematology)
[2021, 96(6):719-726]

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Long-term neurodevelopmental outcome after prenatal exposure to maternal hematological malignancies with or without cytotoxic treatment.

Mathilde van Gerwen, Evangeline Huis In 't Veld, Martine van Grotel, Marry M van den Heuvel-Eibrink, Kristel Van Calsteren, Charlotte Maggen, Vit Drochytek, Giovanna Scarfone, Camilla Fontana, Robert Fruscio, Elyce Cardonick, Elisabeth M van Dijk-Lokkart, Frédéric Amant,

Data on the long-term neurodevelopmental outcomes of children exposed to hematological maternal cancer with or without treatment during pregnancy are lacking. A total of 57 children, of whom 33 males and 24 females, prenatally exposed to hematological malignancies and its treatment, were invited for neuropsychological and physical examinations at 18 months, ... Read more >>

Child Neuropsychol (Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence)
[2021, :1-12]

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Clinical characteristics of subsequent histologically confirmed meningiomas in long-term childhood cancer survivors: A Dutch LATER study.

Lisanne C Verbruggen, Judith L Kok, Jop C Teepen, Geert O Janssens, Charlotte M de Boer, Lukas J A Stalpers, Meike W Vernooij, Eline van Dulmen-den Broeder, Jacqueline J Loonen, Marry M van den Heuvel-Eibrink, Wim J E Tissing, Margriet van der Heiden-van der Loo, Anne Birgitta Versluys, Sebastian J C M M Neggers, Flora E van Leeuwen, Eelco W Hoving, Pieter Wesseling, Leontine C M Kremer, Cécile M Ronckers, Helena J H van der Pal, ,

<h4>Background</h4>Meningiomas are the most frequent brain tumours occurring after pediatric cranial radiotherapy (CrRT). Data on course of disease, to inform clinical management of meningiomas, are sparse. This study reports the clinical characteristics of histologically confirmed meningiomas in childhood cancer survivors (CCS) in the Netherlands.<h4>Methods</h4>In total, 6015 CCS from the Dutch ... Read more >>

Eur J Cancer (European journal of cancer (Oxford, England : 1990))
[2021, 150:240-249]

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Locoregional control using highly conformal flank target volumes and volumetric-modulated arc therapy in pediatric renal tumors: Results from the Dutch national cohort.

Joeri Mul, Martine van Grotel, Enrica Seravalli, Mirjam E Bosman, Harm van Tinteren, Prakriti Roy, Raquel Dávila Fajardo, Godelieve A M Tytgat, Annelies M C Mavinkurve-Groothuis, Cornelis P van de Ven, Marc H W A Wijnen, Ronald R de Krijger, Annemieke S Littooij, Marry M van den Heuvel-Eibrink, Geert O Janssens,

<h4>Background and purpose</h4>In pediatric renal tumors, conventional two opposing photon beams have been used to cover the postoperative flank target volume for decades. This single center study describes the locoregional outcome using highly conformal flank target volumes adjusted for postoperative changes and intra-fraction motion combined with Volumetric-Modulated Arc Therapy (VMAT).<h4>Materials ... Read more >>

Radiother Oncol (Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology)
[2021, 159:249-254]

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Risk factors for steroid-induced adverse psychological reactions and sleep problems in pediatric acute lymphoblastic leukemia: A systematic review.

Annelienke M van Hulst, Shosha H M Peersmann, Erica L T van den Akker, Linda J Schoonmade, Marry M van den Heuvel-Eibrink, Martha A Grootenhuis, Raphaële R L van Litsenburg,

<h4>Objective</h4>Steroids play an essential role in treating pediatric acute lymphoblastic leukemia (ALL). The downside is that these drugs can cause severe side effects, such as adverse psychological reactions (APRs) and sleep problems, which can compromise health-related quality of life. This study aimed to systematically review literature to identify risk factors ... Read more >>

Psychooncology (Psycho-oncology)
[2021, :]

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Inter-clinician delineation variation for a new highly-conformal flank target volume in children with renal tumors: A SIOP-Renal Tumor Study Group international multicenter exercise.

Joeri Mul, Patrick Melchior, Enrica Seravalli, Daniel Saunders, Stephanie Bolle, Alison L Cameron, Kristin Gurtner, Semi Harrabi, Yasmin Lassen-Ramshad, Naomi Lavan, Henriette Magelssen, Henry Mandeville, Tom Boterberg, Petra S Kroon, Alexis N T J Kotte, Bianca A W Hoeben, Peter S N van Rossum, Martine van Grotel, Norbert Graf, Marry M van den Heuvel-Eibrink, Christian Rübe, Geert O Janssens,

<h4>Background and purpose</h4>Recently, the SIOP-RTSG developed a highly-conformal flank target volume definition for children with renal tumors. The aims of this study were to evaluate the inter-clinician delineation variation of this new target volume definition in an international multicenter setting and to explore the necessity of quality assurance.<h4>Materials and methods</h4>Six ... Read more >>

Clin Transl Radiat Oncol (Clinical and translational radiation oncology)
[2021, 28:39-47]

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Effect of post-consolidation regimen on symptomatic osteonecrosis in three DCOG acute lymphoblastic leukemia protocols.

Jenneke E van Atteveld, Hester A de Groot-Kruseman, Marta Fiocco, Maarten H Lequin, Sebastian J C M M Neggers, Saskia M F Pluijm, Inge M van der Sluis, Rob Pieters, Marry M van den Heuvel-Eibrink,

Haematologica (Haematologica)
[2021, 106(4):1198-1201]

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Clinical Characteristics of Invasive Fungal Infections in Pediatric Oncology Patients With Solid Tumors.

Veerle J Ruijters, Natanja Oosterom, Madeleine E M van der Perk, Tom F W Wolfs, Annelot J M Meijer, Marry M van den Heuvel-Eibrink, Martine van Grotel,

Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in children with cancer. Studies on the clinical characteristics of IFI in children with solid tumors are limited. This Dutch retrospective cohort study reviewed the medical records of 61 children with solid tumors to analyze the clinical characteristics ... Read more >>

J Pediatr Hematol Oncol (Journal of pediatric hematology/oncology)
[2021, 43(3):e408-e413]

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Oncofertility care for newly diagnosed girls with cancer in a national pediatric oncology setting, the first full year experience from the Princess Máxima Center, the PEARL study.

M E Madeleine van der Perk, Anne-Lotte L F van der Kooi, Marianne D van de Wetering, Irene M IJgosse, Eline van Dulmen-den Broeder, Simone L Broer, Aart J Klijn, A Birgitta Versluys, Brigitte Arends, Ralph J A Oude Ophuis, Hanneke M van Santen, Alida F W van der Steeg, Margreet A Veening, Marry M van den Heuvel-Eibrink, Annelies M E Bos,

<h4>Background</h4>Childhood cancer patients often remain uninformed regarding their potential risk of gonadal damage. In our hospital we introduced a five step standard oncofertility care plan for all newly diagnosed female patients aiming to identify, inform and triage 100% of patients and counsel 100% of patients at high risk (HR) of ... Read more >>

PLoS One (PloS one)
[2021, 16(3):e0246344]

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Genetic variants associated with methotrexate-induced mucositis in cancer treatment: A systematic review and meta-analysis.

Hedy Maagdenberg, Natanja Oosterom, Jolanda Zanen, Donato Gemmati, Rachael E Windsor, Sandra G Heil, Patricia Esperón, Shakila Jabeen, Guillermo J Ruiz-Argüelles, Oliver Zolk, Susanne Hoerning, Charlotte Sleurs, Elixabet Lopéz-Lopéz, Mónica Moreno-Galván, Marry M van den Heuvel-Eibrink, Anke H Maitland-van der Zee, Bruce C Carleton,

Methotrexate (MTX), an important chemotherapeutic agent, is often accompanied with mucositis. The occurrence and severity are unpredictable and show large interindividual variability. In this study, we review and meta-analyze previously studied genetic variants in relation to MTX-induced mucositis. We conducted a systematic search in Medline and Embase. We included genetic ... Read more >>

Crit Rev Oncol Hematol (Critical reviews in oncology/hematology)
[2021, 161:103312]

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TRIM28 variants and Wilms' tumour predisposition.

Janna A Hol, Illja J Diets, Ronald R de Krijger, Marry M van den Heuvel-Eibrink, Marjolijn Cj Jongmans, Roland P Kuiper,

TRIM28 was recently identified as a Wilms' tumour (WT) predisposition gene, with germline pathogenic variants identified in around 1% of isolated and 8% of familial WT cases. TRIM28 variants are associated with epithelial WT, but the presence of other tumour components or anaplasia does not exclude the presence of a ... Read more >>

J Pathol (The Journal of pathology)
[2021, 254(4):494-504]

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Clinical and Molecular Characteristics and Outcome of Cystic Partially Differentiated Nephroblastoma and Cystic Nephroma: A Narrative Review of the Literature.

Sophie E van Peer, Corine J H Pleijte, Ronald R de Krijger, Marjolijn C J Jongmans, Roland P Kuiper, Marc R Lilien, Martine van Grotel, Norbert Graf, Marry M van den Heuvel-Eibrink, Janna A Hol,

In children presenting with a predominantly cystic renal tumor, the most likely diagnoses include cystic partially differentiated nephroblastoma (CPDN) and cystic nephroma (CN). Both entities are rare and limited information on the clinical and molecular characteristics, treatment, and outcome is available since large cohort studies are lacking. We performed an ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(5):]

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Clinical value of a screening tool for tumor predisposition syndromes in childhood cancer patients (TuPS): a prospective, observational, multi-center study.

Floor A M Postema, Saskia M J Hopman, Corianne A J M de Borgie, Cora M Aalfs, Jakob K Anninga, Lieke P V Berger, Fonnet E Bleeker, Charlotte J Dommering, Natasha K A van Eijkelenburg, Peter Hammond, Marry M van den Heuvel-Eibrink, Janna A Hol, Wijnanda A Kors, Tom G W Letteboer, Jan L C M Loeffen, Lisethe Meijer, Maran J W Olderode-Berends, Anja Wagner, Raoul C Hennekam, Johannes H M Merks,

Recognizing a tumor predisposition syndrome (TPS) in a child with cancer is of clinical relevance. Earlier we developed a screening tool to increase diagnostic accuracy and clinical efficiency of identifying TPSs in children with cancer. Here we report on the value of this tool in clinical practice. TuPS is a ... Read more >>

Fam Cancer (Familial cancer)
[2021, :]

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Maternal and Neonatal Outcome after the Use of G-CSF for Cancer Treatment during Pregnancy.

Claudia Berends, Charlotte Maggen, Christianne A R Lok, Mathilde van Gerwen, Ingrid A Boere, Vera E R A Wolters, Kristel Van Calsteren, Heidi Segers, Marry M van den Heuvel-Eibrink, Rebecca C Painter, Mina Mhallem Gziri, Frédéric Amant,

Data on the use of Granulocyte colony-stimulating factor (G-CSF) in pregnant cancer patients are scarce. The International Network of Cancer, Infertility and Pregnancy (INCIP) reviewed data of pregnant patients treated with chemotherapy and G-CSF, and their offspring. Among 2083 registered patients, 42 pregnant patients received G-CSF for the following indications: ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(6):]

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Possible modification of BRSK1 on the risk of alkylating chemotherapy-related reduced ovarian function.

Anne-Lotte L F van der Kooi, Marloes van Dijk, Linda Broer, Marleen H van den Berg, Joop S E Laven, Flora E van Leeuwen, Cornelis B Lambalk, Annelies Overbeek, Jacqueline J Loonen, Helena J van der Pal, Wim J Tissing, Birgitta Versluys, Dorine Bresters, Catharina C M Beerendonk, Cécile R Ronckers, Margriet van der Heiden-van der Loo, Gertjan L Kaspers, Andrica C H de Vries, Leslie L Robison, Melissa M Hudson, Wassim Chemaitilly, Julianne Byrne, Claire Berger, Eva Clemens, Uta Dirksen, Jeanette Falck Winther, Sophie D Fosså, Desiree Grabow, Riccardo Haupt, Melanie Kaiser, Tomas Kepak, Jarmila Kruseova, Dalit Modan-Moses, Saskia M F Pluijm, Claudia Spix, Oliver Zolk, Peter Kaatsch, Jesse H Krijthe, Leontien C Kremer, Yutaka Yasui, Russell J Brooke, André G Uitterlinden, Marry M van den Heuvel-Eibrink, Eline van Dulmen-den Broeder,

<h4>Study question</h4>Do genetic variations in the DNA damage response pathway modify the adverse effect of alkylating agents on ovarian function in female childhood cancer survivors (CCS)?<h4>Summary answer</h4>Female CCS carrying a common BR serine/threonine kinase 1 (BRSK1) gene variant appear to be at 2.5-fold increased odds of reduced ovarian function after ... Read more >>

Hum Reprod (Human reproduction (Oxford, England))
[2021, 36(4):1120-1133]

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Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.

Lars Custers, Eleonora Khabirova, Tim H H Coorens, Thomas R W Oliver, Camilla Calandrini, Matthew D Young, Felipe A Vieira Braga, Peter Ellis, Lira Mamanova, Heidi Segers, Arie Maat, Marcel Kool, Eelco W Hoving, Marry M van den Heuvel-Eibrink, James Nicholson, Karin Straathof, Liz Hook, Ronald R de Krijger, Claire Trayers, Kieren Allinson, Sam Behjati, Jarno Drost,

Malignant rhabdoid tumour (MRT) is an often lethal childhood cancer that, like many paediatric tumours, is thought to arise from aberrant fetal development. The embryonic root and differentiation pathways underpinning MRT are not firmly established. Here, we study the origin of MRT by combining phylogenetic analyses and single-cell mRNA studies ... Read more >>

Nat Commun (Nature communications)
[2021, 12(1):1407]

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Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group.

Renée L Mulder, Anna Font-Gonzalez, Eline van Dulmen-den Broeder, Gwendolyn P Quinn, Jill P Ginsberg, Erik A H Loeffen, Melissa M Hudson, Karen C Burns, Hanneke M van Santen, Claire Berger, Tamara Diesch, Uta Dirksen, Aleksander Giwercman, Clarisa Gracia, Sarah E Hunter, Joanne F Kelvin, James L Klosky, Joop S E Laven, Barbara A Lockart, Sebastian J C M M Neggers, Michelle Peate, Bob Phillips, Damon R Reed, Eva Maria E Tinner, Julianne Byrne, Margreet Veening, Marleen van de Berg, Chris M Verhaak, Antoinette Anazodo, Kenny Rodriguez-Wallberg, Marry M van den Heuvel-Eibrink, Ogechukwu A Asogwa, Alexandra Brownsdon, W Hamish Wallace, Daniel M Green, Roderick Skinner, Riccardo Haupt, Lisa B Kenney, Jennifer Levine, Marianne D van de Wetering, Wim J E Tissing, Norbert W Paul, Leontien C M Kremer, Julia Inthorn, ,

Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-related infertility risk and procedures for fertility preservation does not always happen. The PanCareLIFE Consortium and the ... Read more >>

Lancet Oncol (The Lancet. Oncology)
[2021, 22(2):e68-e80]

Cited: 3 times

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Outcome of Stage IV Completely Necrotic Wilms Tumour and Local Stage III Treated According to the SIOP 2001 Protocol.

Raquel Dávila Fajardo, Rhoikos Furtwängler, Martine van Grotel, Harm van Tinteren, Claudia Pasqualini, Kathy Pritchard-Jones, Reem Al-Saadi, Beatriz de Camargo, Gema L Ramírez Villar, Norbert Graf, Xavier Muracciole, Patrick Melchior, Daniel Saunders, Christian Rübe, Marry M van den Heuvel-Eibrink, Geert O Janssens, Arnauld C Verschuur,

<h4>Objective</h4>Wilms tumour (WT) patients with a localised completely necrotic nephroblastoma after preoperative chemotherapy are a favourable outcome group. Since the introduction of the SIOP 2001 protocol, the SIOP- Renal Tumour Study Group (SIOP-RTSG) has omitted radiotherapy for such patients with low-risk, local stage III in an attempt to reduce treatment ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(5):]

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Health-Related Quality of Life in European Childhood Cancer Survivors: Protocol for a Study Within PanCareLIFE.

Gabriele Calaminus, Katja Baust, Claire Berger, Julianne Byrne, Harald Binder, Leonie Casagranda, Desiree Grabow, Martha Grootenhuis, Peter Kaatsch, Melanie Kaiser, Tomas Kepak, Kateřina Kepáková, Leontien C M Kremer, Jarmila Kruseova, Ales Luks, Claudia Spix, Marleen van den Berg, Marry M M van den Heuvel-Eibrink, Eline van Dulmen-den Broeder, Rahel Kuonen, Grit Sommer, Claudia Kuehni,

<h4>Background</h4>Survival after childhood cancer has improved to more than 80% during the last few years, leading to an increased number of childhood cancer survivors. Cancer itself, or its treatment, may cause chronic health conditions, including somatic and mental sequelae, which may affect survivors' health-related quality of life (HRQoL).<h4>Objective</h4>The project PanCareLIFE ... Read more >>

JMIR Res Protoc (JMIR research protocols)
[2021, 10(1):e21851]

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Fatigue among children with a chronic disease: a cross-sectional study.

Merel M Nap-van der Vlist, Geertje W Dalmeijer, Martha A Grootenhuis, Kors van der Ent, Marry M van den Heuvel-Eibrink, Joost F Swart, Elise M van de Putte, Sanne L Nijhof,

<h4>Objective</h4>To determine: (1) which biological/lifestyle, psychological and/or social factors are associated with fatigue among children with a chronic disease and (2) how much each of these factors contributes to explaining variance in fatigue.<h4>Design and setting</h4>This was a cross-sectional study across two children's hospitals.<h4>Patients</h4>We included children aged 8-18 years who visited the ... Read more >>

BMJ Paediatr Open (BMJ paediatrics open)
[2021, 5(1):e000958]

Cited: 1 time

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Fertility preservation for male patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group.

Renée L Mulder, Anna Font-Gonzalez, Daniel M Green, Erik A H Loeffen, Melissa M Hudson, Jacqueline Loonen, Richard Yu, Jill P Ginsberg, Rod T Mitchell, Julianne Byrne, Roderick Skinner, Antoinette Anazodo, Louis S Constine, Andrica de Vries, Kirsi Jahnukainen, Armando Lorenzo, Andreas Meissner, Leena Nahata, Marij Dinkelman-Smit, Herman Tournaye, Riccardo Haupt, Marry M van den Heuvel-Eibrink, Hanneke M van Santen, Ans M M van Pelt, Uta Dirksen, Jaap den Hartogh, Eline van Dulmen-den Broeder, W Hamish Wallace, Jennifer Levine, Wim J E Tissing, Leontien C M Kremer, Lisa B Kenney, Marianne D van de Wetering, ,

Male patients with childhood, adolescent, and young adult cancer are at an increased risk for infertility if their treatment adversely affects reproductive organ function. Future fertility is a primary concern of patients and their families. Variations in clinical practice are barriers to the timely implementation of interventions that preserve fertility. ... Read more >>

Lancet Oncol (The Lancet. Oncology)
[2021, 22(2):e57-e67]

Cited: 2 times

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